Circle Cardiovascular Imaging

What Circle Cardiovascular Imaging does

Circle Cardiovascular Imaging (Circle CVI), founded in 2007 in Calgary, Canada, develops and markets cvi42, a vendor-agnostic post-processing software platform for cardiovascular and neurovascular imaging analysis. The platform is deployed across 1,700+ hospital sites in 90+ countries, including 70% of the world's top 50 hospitals (per Newsweek 2023 rankings), and processes 50,000+ cardiac scans daily. cvi42 spans cardiac MR, cardiac CT, vascular CT, interventional planning (TAVR/TMVR/WATCHMAN), electrophysiology, and acute stroke imaging (StrokeSENS), integrating with all major scanner vendors (GE, Siemens, Philips, Canon), PACS systems via DICOM, and reporting systems via HL7. The company is privately held under Thoma Bravo ownership following a 2022 growth investment, with 101-250 employees and wholly-owned subsidiaries in the UK, Netherlands, and USA.

The cvi42 platform is built around AI-powered image analysis using convolutional neural networks trained on multi-vendor, multi-center datasets including UK Biobank. AI capabilities include automated cardiac contouring and segmentation, zero-click calcium scoring, AI-enabled coronary plaque quantification (FDA-cleared cvi42 | Plaque), 4D Flow analysis, automated ASPECTS scoring, and LVO detection for stroke triage. AI models are frozen, encrypted, and run on-premise, ensuring patient data never leaves the institution. The company holds multiple FDA 510(k) clearances, EU MDR CE mark, ISO 13485:2016, MDSAP certification, and regulatory approvals in 20+ jurisdictions.

Circle CVI generates revenue through a hybrid model combining annual subscription licensing (including the cvi42 | Elevate flexible subscription and module-specific add-ons), usage-based per-case fees for AI-enabled plaque analysis (now reimbursable under new CPT code 75577 at ~$950-$1,012 per case), enterprise site licenses, and professional services for implementation and HL7 integration. Distribution combines direct enterprise sales, OEM integration with GE Healthcare and Siemens Healthineers, a 600+ OEM distributor network, and self-serve trial downloads. The company serves hospital systems, academic medical centers, cardiology and radiology departments, structural heart and EP programs, and rural/community hospitals globally.

Name

Circle Cardiovascular Imaging

Legal name

Circle Cardiovascular Imaging Inc.

Website

https://circlecvi.com

Company type

Private

Founded year

2007

Operating status

Operating

Headcount range

101–250 employees

Short description

Circle Cardiovascular Imaging develops cvi42, a vendor-agnostic AI-powered cardiovascular and neurovascular imaging post-processing platform. Deployed across 1,700+ hospital sites in 90+ countries, serving cardiology, radiology, and stroke programs globally.

Ownership category

akta.pro rank

Product category

Cardiovascular Imaging Software

NAICS

Software Publishers (513210)

SIC

Surgical & Medical Instruments & Apparatus (3841)

akta.pro primary industry

Imaging & Cardiac Safety Core Labs (ECOG/EEG/ECG) (HLAGAAAJ)

akta.pro secondary industry

Decentralized/Hybrid Trial Enablement (DCT) Platforms (HLACAOAL)

Keywords

• Cardiovascular imaging software
• Cardiac MR analysis
• Coronary plaque analysis
• Medical imaging AI
• Post-processing software

Headquarters

HQ city

Calgary

HQ country

Canada

HQ region

North America

Offices2 records

Markets served

GTM type

B2B

Offering type

Software

Cost components

Technology or R&D, Personnel, Marketing or Sales, Operations, Others

Revenue model

1. Software Licenses (Subscription): Annual subscription model for cvi42 platform access. Flexible subscription model (cvi42 | Elevate) provides scalable access to CMR and CCT functionalities with unlimited usage. Sites can subscribe to specific modules based on their needs.
2. Per-Use/Transaction Revenue: Usage-based pricing for plaque analysis processing. Sites pay for what they process at a per-case rate, particularly for cvi42 | Plaque workflow. Reimbursable under CPT code 75577 for AI-enabled coronary plaque analysis.
3. Professional Services: Implementation services, training, and technical support services. HL7 integration services available as additional purchase. Initial setup and configuration support for enterprise deployments.

Pricing tiers

Go-to-market motion4 records

Distribution channels5 records

Marketing channels6 records

Core offering

Circle Cardiovascular Imaging develops and markets cvi42, a vendor-agnostic AI-powered post-processing platform for cardiovascular and neurovascular imaging. The software provides automated quantification and analysis of cardiac MR, cardiac CT, vascular CT, structural heart interventional planning, electrophysiology, and acute stroke imaging, deployed at hospital systems and academic medical centers. It sells primarily through annual subscriptions, usage-based pricing for plaque analysis, and OEM integrations with GE Healthcare and Siemens Healthineers.

Product overview

Circle Cardiovascular Imaging offers cvi42, a unified, vendor-agnostic cardiovascular imaging platform. The platform is built around a core cvi42 software that supports all operating systems (Mac and Windows) and all scanner vendors, deployed as standalone workstation or Client/Server. The platform integrates modules for Cardiac MR (function, flow, tissue characterization, strain, 4D Flow, perfusion), Cardiac CT (CORE CT with coronaries/calcium/function/strain, Plaque analysis, PCAT), Vascular CT (via Astute Imaging), Interventional Planning (TruPlan, aortic/mitral valve), Electrophysiology (ADAS 3D), and Neuro CT (StrokeSENS for LVO and ASPECTS). The cvi42 platform serves over 1,700 hospitals in more than 90 countries and processes scans daily.

Differentiator

Problem solved

Functional benefit

Brands

• cvi42: The company's flagship cardiovascular imaging software platform providing quantitative and qualitative assessment of cardiac MR, cardiac CT, vascular CT, and neuro CT.
• StrokeSENS
• cvi42 | Plaque
• TruPlan
• cvi42 | Vascular CT

Products and services

• cvi42 Flagship vendor-agnostic cardiovascular imaging platform providing quantitative and qualitative assessment across cardiac MR, cardiac CT, vascular CT, and neuro CT. Supports all major scanner vendors and runs on Mac and Windows, deployed as a standalone workstation or Client/Server, and integrates with PACS, PowerScribe, and hospital reporting systems via HL7 and DICOM.
• cvi42 | Plaque FDA-cleared AI-enabled coronary plaque analysis module providing on-premise quantification of atherosclerotic burden from CCTA studies, including automated coronary lumen and wall segmentation, per-lesion and per-vessel analysis of calcified, non-calcified, and low-attenuation plaque, and remodeling index assessment for high-risk plaque identification.
• cvi42 | Vascular CT AI-enabled vascular CT analysis module for aortic (AAA, TAA), carotid, and peripheral artery assessment, powered by Astute Imaging technology. Features AI-powered segmentation of lumen, thrombus, calcium, and plaque, automated centerline extraction, virtual graft simulation with FEM analysis, and bilateral comparison for disease progression tracking. Licensed by Astute Imaging and distributed by Circle CVI.
• StrokeSENS AI-based stroke imaging software for front-line physicians. Includes StrokeSENS LVO for flagging and prioritizing suspected Large Vessel Occlusion on CT/CTA, and StrokeSENS ASPECTS for automatic Alberta Stroke Program Early CT Score scoring on non-contrast CT. FDA-cleared and CE-marked, and available via GE AW workstation/server, Siemens syngo.via, and Aidoc's aiOS platform.
• cvi42 | Interventional Planning (TruPlan) Pre-procedural planning module for structural heart interventions including WATCHMAN TruPlan for left atrial appendage closure (LAA assessment, fluoro/TEE/ICE simulation, follow-up PDL measurement), Aortic Valve planning (annulus measurements, cusp detection, virtual device visualization, femoral access planning), and Mitral Valve planning (annulus contouring, LVOT assessment, neo-LVOT, apical access planning, trans-septal measurements).
• cvi42 | Electrophysiology (ADAS 3D) Pre-procedural imaging tools for electrophysiologists, using ADAS 3D (licensed and manufactured by Adas3D Medical and distributed by Circle CVI). ADAS 3D LV visualizes and quantifies LV fibrosis (MR) and anatomical structures (CT) with myocardial layer display, while ADAS 3D LA visualizes fibrosis distribution in 3D from late enhancement MR with adjacent structure display.

Quantifiable outcome

• Customer Satisfaction Score (CSAT) of 4.9 out of 5 with 98% satisfaction rate
• +5 more outcomes

Named customers12 records

Segments4 records

Ideal customer profiles2 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration7 records

AI capability5 records

Feature8 records

Partnerships

Four partnerships are on record, tiered core and strategic.

• Astute ImagingcoreStrategic or Co-development Partner · 18 March 2026Strategic collaboration integrating Astute Imaging's AI-driven vascular analysis technology (aorta, carotid, peripheral arteries) into cvi42 platform. Enables comprehensive cardiovascular workflows including cardiac, vascular, and structural heart analysis in unified platform.
• AidocstrategicStrategic or Co-development Partner · 18 December 2025Strategic partnership integrating Circle's automated ASPECTS capabilities into Aidoc's aiOS enterprise operating system for neurosciences AI. Enhances Aidoc's stroke diagnosis portfolio with Circle's MR perfusion and automated ASPECTS tools.
• GE HealthcarecoreTechnology or Integrationcvi42 integrated into GE AW workstation and AW Server. Native integration enables seamless cardiac imaging workflow for GE customers. StrokeSENS also integrated into GE FastStroke software package.
• Siemens HealthineerscoreTechnology or Integrationcvi42 available on Siemens Healthineers syngo.via workstation. Seamless integration enables cardiac imaging analysis within existing Siemens clinical workflow. StrokeSENS also available on Siemens platforms.

Scale indicators10 records

Recent moves7 records

Expansion highlights6 records

Broad incumbents

• GE HealthCare: GE HealthCare's AW Workstation and AW Server bundle Circle's cvi42 alongside GE's own AI imaging portfolio (including FastStroke). GE is both a critical OEM distribution channel and a potential competitor as it expands proprietary AI capabilities.
• Siemens Healthineers: Siemens Healthineers' syngo.via is both an OEM distribution partner for Circle (cvi42 is integrated into syngo.via) and a direct competitor offering its own AI-powered cardiovascular and CT post-processing tools within the same enterprise accounts.
• Philips: Philips offers IntelliSpace Portal and a dedicated Cardiovascular Workspace for advanced MR/CT post-processing. It is a broad incumbent imaging vendor that competes head-to-head with cvi42 in hospital cardiology and radiology departments globally.

Direct peers

• RapidAI: RapidAI offers AI-powered stroke and vascular imaging analysis, directly competing with StrokeSENS in LVO detection, ASPECTS scoring, and CT/MR perfusion quantification across hospital systems.
• HeartFlow: HeartFlow provides AI-driven coronary CT analysis (FFR-CT) for coronary artery disease assessment. It directly competes with cvi42 | Plaque in the CCTA post-processing market and targets the same cardiology departments.
• Cleerly: Cleerly is an AI-native direct competitor to cvi42 | Plaque, focused exclusively on coronary plaque quantification and CAD risk stratification from CCTA. Both companies target the same CPT 75577 reimbursement-driven US opportunity.
• Medis Medical Imaging: Medis is a closely comparable niche cardiovascular imaging software vendor offering post-processing for cardiac MR, CT, and IVUS. It competes with Circle in academic medical centers and tertiary cardiac centers, particularly in Europe.
• Viz.ai: Viz.ai is the leading AI stroke detection and workflow platform, directly competing with Circle's StrokeSENS module for LVO detection and ASPECTS scoring in hospital neurology and stroke programs.
• Aidoc: Aidoc is both a Circle partner (Circle's stroke AI is integrated into Aidoc's aiOS) and a broader AI imaging competitor across neurology, cardiology, and radiology workflows. Its enterprise AI operating system overlaps with Circle's hospital penetration strategy.
• Elucid Bioimaging: Elucid provides AI-based cardiovascular imaging analysis with a focus on plaque characterization and histology-validated quantification. It competes with cvi42 | Plaque in the coronary CT analysis category.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat6 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/circlecvi

Compliance5 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles7 records

Subsidiaries3 records

Funding overview

Funding rounds5 records

Investors9 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A1 record

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Circle Cardiovascular Imaging