Calice

What Calice does

Calice is a Buenos Aires-based computational agricultural science company founded in 2021 that operates as "The Virtual Field Trials Company." It has developed an Environmental Engine that simulates how agricultural products—seeds, biologicals, and crop protection chemicals—perform across thousands of environments by modeling Product × Environment × Management (P×E×M) interactions from biological first principles rather than statistical correlations. The platform generates Performance Probability Maps and Environmental Fingerprint Analysis outputs, enabling R&D and portfolio teams to identify optimal product placement zones and stress scenarios before committing to physical field trials. Its core technical architecture combines systems biology, AI, and chronobiology to produce robust predictions even with noisy, incomplete, or heterogeneous agricultural data, and the company positions this as differentiated versus traditional statistical agronomy models.

Calice delivers its Environmental Engine through three modalities: a web-based Platform for direct access, Decision-Ready Reports for customized R&D pipeline integration, and an API for embedding environmental intelligence into customer software stacks. Its GTM is enterprise field sales targeting seed companies, biologicals developers, crop protection companies, and commodities players globally, with named enterprise customers spanning Syngenta, Corteva, BASF, Nufarm, GDM, TMG, Nuseed, Boortmalt, Puna.bio, CIMMYT, and CoverCress. Pricing is custom and quote-based; revenue streams are subscription/recurring for platform and reports plus usage-based for API. The company maintains offices in Buenos Aires (headquarters), San Francisco, and São Paulo, with active projects across Argentina, Brazil, Mexico, the USA, France, Belgium, Greece, Turkey, and Australia.

The company is venture-backed with $3.5M in total disclosed funding across rounds in 2022, 2024, and 2025, with investors including Astanor Ventures, Draper Cygnus, GrainCorp Ventures, Xperiment Ventures, AIR Capital, and Innventure. It operates with a team of approximately 25 experts led by four co-founders—Ramiro Olivera (CEO, prior CSO at Kheiron), Esteban Hernando (CSO, PhD Molecular Biology, 10 years at CONICET/Instituto Leloir), Pablo Romero (COO/CFO, former Operations Lead at Mercado Libre), and Andres Rabinovich (CTO, PhD Physics and Systems Biology)—alongside a CCO with 11 years at Monsanto. The company is recognized as one of the "10 Rising AI Startups in Latin America 2026" by Latam Republic.

Name

Calice

Legal name

Calice

Website

https://calice.ai

Company type

Private

Founded year

2021

Operating status

Operating

Headcount range

11–50 employees

Short description

Calice is an Argentine AgTech company that runs virtual field trials through its proprietary Environmental Engine, serving R&D and portfolio teams at seed, biologicals, and crop protection enterprises across Latin America, North America, Europe, and Australia.

Ownership category

akta.pro rank

Product category

Agricultural R&D Analytics Software

NAICS

Support Activities for Crop Production (11511)

SIC

Agricultural Services (700)

akta.pro primary industry

Farm Management & Decision Support Software (FMIS, ERP, Recordkeeping) (AFAGALAA)

akta.pro secondary industries

Farm Data Management & Decision Support Services (FMIS Setup, Data Integration, Analytics) (AFACACAC), Interoperability & Data Connectivity Services (API/ETL, ISOXML/AgGateway, Equipment Data Sync) (AFACACAL)

Keywords

• Virtual field trials
• Computational agronomy
• Agricultural R&D analytics
• Crop performance modeling
• Agricultural decision intelligence

Headquarters

HQ city

San Martin

HQ country

Argentina

HQ region

Latin America

Offices3 records

Markets served

GTM type

B2B

Offering type

Software

Cost components

Personnel, Technology or R&D, Operations, Marketing or Sales, Others

Revenue model

1. Platform Access: Web-based platform access for R&D and portfolio teams to evaluate agricultural product performance across multiple environments. Delivered as Software-as-a-Service with subscription or usage-based pricing.
2. Decision-Ready Reports: Custom reports providing insights integrated into existing R&D and portfolio pipelines for agricultural decision-making.
3. API Integration: API-based integration allowing agricultural companies to embed Calice's environmental intelligence into their own systems and workflows.

Go-to-market motion1 record

Distribution channels3 records

Marketing channels4 records

Core offering

Calice provides a computational agricultural science platform called the Environmental Engine that runs Virtual Field Trials, simulating how agricultural products (seeds, biologicals, crop protection) perform across thousands of environments by modeling Product × Environment × Management interactions from biological first principles. It is sold to enterprise agricultural R&D and portfolio teams through a web-based Platform, customized Decision-Ready Reports, and an API integration, generating Performance Probability Maps and Environmental Fingerprint Analysis outputs to support product placement and breeding decisions before committing to physical trials.

Product overview

Calice is a computational agricultural science company that operates as 'The Virtual Field Trials Company.' Its core offering is the Environmental Engine, which powers virtual field trials through three delivery methods: a web-based Platform, Decision-Ready Reports, and API Integration. The platform generates Performance Probability Maps and Environmental Fingerprint Analysis as its primary analytical outputs, enabling R&D and portfolio teams to evaluate agricultural products across thousands of simulated environments before committing to physical field trials. The system models Product × Environment × Management (P×E×M) interactions from biological first principles to produce Decision-Ready Outputs integrated into existing R&D pipelines.

Differentiator

Problem solved

Functional benefit

Products and services

• Environmental Engine (Virtual Field Trials Platform) Core computational agricultural science platform that runs Virtual Field Trials, simulating how agricultural products (seeds, biologicals, crop protection) perform across thousands of environments by modeling Product × Environment × Management interactions from biological first principles. Delivered to enterprise agricultural R&D and portfolio teams via web access, with outputs including Performance Probability Maps and Environmental Fingerprint Analysis.
• Decision-Ready Reports Customized, pre-formatted decision-ready reports delivering virtual field trial insights and Environmental Fingerprint Analysis for agricultural R&D and portfolio teams. Insights are integrated into existing R&D and portfolio pipelines without requiring restructuring of workflows.
• API Integration API-based integration that enables enterprise agricultural companies to embed Calice's environmental intelligence and virtual field trial capabilities directly into their own R&D software systems and workflows.

Quantifiable outcome

• Reduced import dependency and improved portfolio resilience for barley sourcing under climate variability
• +4 more outcomes

Named customers11 records

Segments4 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

Yes

API docs

API detail

Core technology

AI maturity

App detail

AI capability2 records

Feature4 records

Scale indicators4 records

Recent moves8 records

Expansion highlights6 records

Broad incumbents

• Bayer Climate LLC (Climate FieldView): Bayer-owned digital agriculture platform combining field data collection, predictive modeling, and decision support for farmers and agribusiness. Most directly comparable incumbent to Calice on environmental modeling and field-trial analytics, though embedded within Bayer's broader seed-and-chemical portfolio rather than sold independently.
• Syngenta Cropwise: Syngenta's digital agriculture platform offering predictive analytics, field insights, and recommendation tools to growers and enterprise users. Directly comparable as a competitor in environmental/decision intelligence sold into the same ag-input R&D ecosystem, but owned and operated by one of Calice's named customers.
• Corteva Agrimine / Granular: Corteva's digital agriculture suite (combining Granular farm management and agronomy analytics) targeting enterprise R&D and grower decision support. Comparable to Calice in the analytics layer but embedded within a major ag-input conglomerate and focused more on farm operations than on virtual product-trial simulation.
• Indigo Ag: Digital agriculture and biologicals company combining microbial products with agronomic data analytics and Marketplace commerce. Comparable to Calice in the agronomic analytics layer and as a partner/customer to biologicals companies, though Indigo operates a vertically integrated biologicals business rather than a pure software model.
• Proagrica (Lexagri / AgSolutions): Global agricultural data and analytics business (part of Lexagri/RELX group) providing data infrastructure, agronomic insights, and supply-chain traceability to ag-input and agribusiness customers. Comparable to Calice as an enterprise-grade analytics vendor targeting seed and crop-protection R&D organizations.

Direct peers

• Taranis: AI-powered precision agriculture intelligence platform delivering crop insights, field-level analytics, and predictive recommendations to ag-input companies and growers. Closest independent competitor to Calice on AI-driven agronomic decision support sold to enterprise agribusiness customers.
• CropX: Precision agriculture analytics company combining soil sensing, weather data, and AI to deliver decision-support recommendations for irrigation, nutrition, and crop protection. Directly comparable to Calice as an independent ag-analytics vendor using modeling to optimize product/environment interactions, though more on-farm-centric than product-trial-centric.
• Semios: Data-driven agriculture platform using IoT sensors, weather data, and predictive models to support decisions across pest management, irrigation, and crop protection. Directly comparable to Calice as an independent precision-ag decision-support vendor with enterprise ag-input customers and a focus on environmental modeling.
• aWhere: Provider of agronomic intelligence combining satellite weather, crop modeling, and analytics for agribusiness and development-sector clients. Directly comparable to Calice's environmental modeling capabilities and enterprise customer base, with longer operating history in the same decision-support category.

Emerging players

• Solvi (formerly Aluma / Intelinair): AI-powered crop analytics platform combining aerial imagery, computer vision, and field-level analytics for ag-input companies and growers. Comparable emerging competitor to Calice on AI-driven agronomic insights, with stronger imagery-centric capability and similar enterprise go-to-market into seed/crop-protection R&D.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks3 records

Key highlights7 records

Customer concentration

• Xx.com/caliceai
• LinkedInlinkedin.com/company/calice-ai
• Instagraminstagram.com/calice.ai

Revenue estimate

Valuation estimate

Number of profiles

Profiles8 records

Funding overview

Funding rounds3 records

Investors7 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Calice