PeptiSystems
PeptiSystems AB designs and manufactures flow-through column synthesis instruments and PeptiSoft software for solid-phase peptide and oligonucleotide therapeutics, serving pharmaceutical companies and CDMOs from lab to commercial GMP scale.
- Company typePrivate
- Founded2014
- HeadquartersUppsala, Sweden
- Headcount1–10
- GTM typeB2B
- OfferingHardware or Manufacturing
What PeptiSystems does
PeptiSystems AB is a Sweden-based privately held instrumentation company founded in 2014 in Uppsala that designs and manufactures flow-through column synthesis instruments for solid-phase peptide and oligonucleotide therapeutics. Its product portfolio covers the full development-to-manufacturing scale: PeptiPilot (0.1–12 mmol) and PeptiPro (10 mmol–10 mol per batch) for peptides, and OligoNavigator, OligoNavigator Plus, and OligoNavigator Pro (0.1 mmol–5 mol) for oligonucleotides, all controlled by PeptiSoft synthesis management software. The proprietary continuous-flow architecture allows linear scale-up without re-optimization from development to commercial GMP batches, claims 50–90% reduction in synthesis cycle time, 50–70% lower solvent consumption, ~15% improvement in purity/yield, and up to 50% CO2 reduction, with one PeptiPro reportedly displacing up to five traditional batch reactors.
The company sells customized instruments directly to pharmaceutical manufacturers and Contract Development and Manufacturing Organizations (CDMOs) for both GMP and non-GMP production, and supports customers in North/South America, China, and India through three regional channel partners (ATG Service USA, GENECO Service China, BioZed Engineering in India). Revenue mechanics are dominated by hardware sales with multi-year contracts, supplemented by PeptiSoft software (one-time license with 21 CFR Part 11 compliance features), proprietary stainless-steel columns and consumables, and IQ/OQ qualification services. Go-to-market is enterprise field sales layered with industry conference presence (TIDES, IOPC, OTS, RNA Leaders), targeted scientific publications, and an exclusive global co-development partnership with Asahi Kasei Bioprocess America for integrated peptide synthesis solutions. The company is pre-scale, with approximately 20 employees, and has raised capital from Sciety, ALMI Invest, and Rubicon Healthcare Partners (now largest shareholder as of November 2025).
PeptiSystems firmographics
Firmographics- Name
- PeptiSystems
- Legal name
- PeptiSystems AB
- Website
- https://peptisystems.com
- Company type
- Private
- Founded year
- 2014
- Operating status
- Operating
- Headcount range
- 1–10 employees
- Short description
- PeptiSystems AB designs and manufactures flow-through column synthesis instruments and PeptiSoft software for solid-phase peptide and oligonucleotide therapeutics, serving pharmaceutical companies and CDMOs from lab to commercial GMP scale.
- Ownership category
- akta.pro rank
PeptiSystems industry classification
Industry- Product category
- Peptide and Oligonucleotide Synthesis Instruments
- NAICS
- Analytical Laboratory Instrument Manufacturing (334516), Software Publishers (513210)
- SIC
- Laboratory Analytical Instruments (3826)
- akta.pro primary industry
- GMP Scale-Up, Tech Transfer & Process Validation (PPQ) (HLAGAHAL)
- akta.pro secondary industry
- CMC & Pharmaceutical Development (Formulation/Process/Analytical Development) (HLAIALAD)
Keywords
Where PeptiSystems is headquartered
LocationHeadquarters
- HQ city
- Uppsala
- HQ country
- Sweden
- HQ region
- Europe
Offices4 records
Markets served
PeptiSystems business model
Business model- GTM type
- B2B
- Offering type
- Hardware or Manufacturing
- Cost components
- Personnel, Technology or R&D, Supply Chain, Marketing or Sales, Operations
Revenue model
- Instrument Sales: Sale of peptide and oligonucleotide synthesizer instruments (PeptiPilot, PeptiPro, OligoNavigator, OligoNavigator Plus, OligoNavigator Pro). Instruments range from lab scale (0.1-12 mmol) to manufacturing scale (up to 10 mol).
- Software (PeptiSoft): Sale of PeptiSoft synthesis management software with 21 CFR Part 11 compliance. Includes real-time monitoring, synthesis control, and documentation features.
- Accessories and Consumables: Proprietary stainless steel columns (6 sizes), amidite and amino acid containers, and related accessories for the synthesizer instruments.
- Installation and Qualification Services: Installation and Operational Qualification (IQ/OQ) documentation available for GMP synthesis instruments.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| Other | Multi-year contract | Custom instrument pricing based on specifications |
| Other | Multi-year contract | PeptiPro Manufacturing Scale |
Go-to-market motion2 records
Distribution channels4 records
Marketing channels5 records
PeptiSystems product offering
Product offeringCore offering
PeptiSystems designs, manufactures, and supplies automated peptide and oligonucleotide synthesizer instruments based on proprietary flow-through column technology for solid-phase synthesis. The portfolio spans lab-scale process development (0.1 mmol) to large-scale GMP manufacturing (up to 10 mol per batch), and is targeted at pharmaceutical companies, CDMOs, and biotech firms producing peptide and oligonucleotide therapeutics. The instruments are paired with PeptiSoft synthesis management software and proprietary columns and consumables.
Product overview
PeptiSystems offers a portfolio of flow-through column synthesis instruments for peptide and oligonucleotide therapeutics, comprising three product lines organized by scale: PeptiPilot and PeptiPro for peptide synthesis (lab to manufacturing scale), and OligoNavigator, OligoNavigator Plus, and OligoNavigator Pro for oligonucleotide synthesis (lab to manufacturing scale). All instruments are controlled by PeptiSoft® synthesis management software, which provides unified process control and monitoring across the entire product range. Accessories include proprietary stainless steel columns in six sizes. The portfolio enables linear scale-up from development (0.1 mmol) to manufacturing scale (up to 10 mol for peptides, 5 mol for oligonucleotides) using the same synthesis parameters and software platform.
Differentiator
Problem solved
Functional benefit
Brands
- PeptiPilot: Lab scale peptide synthesizer for process development and small-scale synthesis (0.1-12 mmol scale) using flowthrough column technology.
- PeptiPro
- OligoNavigator
- OligoNavigator Plus
- OligoNavigator Pro
- PeptiSoft
Products and services
- PeptiPilot® Fully automated lab-scale peptide synthesizer using flow-through column technology, designed for process development and small-scale synthesis in the 0.1–12 mmol scale range. Features real-time monitoring, elevated temperature synthesis up to 70°C, and linear scalability to production-scale PeptiPro instruments. Targeted at pharma and biotech process development teams.
- PeptiPro® Fully automated large-scale peptide synthesizer covering 10 mmol to 10 mol per batch, enabling production of hundreds of kilograms to metric tons of peptides annually. Replaces up to five traditional batch reactor instruments with 50–90% reduction in synthesis time and supports both GMP and non-GMP production. Targeted at pharmaceutical manufacturers and CDMOs.
- OligoNavigator® Compact, pump-driven lab-scale oligonucleotide synthesizer for process development and small-scale synthesis in the 0.1–12 mmol range. Features five column positions, up to 14 amidite monomer inlets, and in-line monitoring with conductivity and diode-array detectors. Targeted at oligonucleotide process development teams.
- OligoNavigator® Plus Fully automated middle-scale oligonucleotide synthesizer for process development and small-scale manufacturing in the 1–30 mmol range. Features extended monitoring capabilities, elevated temperature synthesis up to 50°C, and seamless scale-up to OligoNavigator Pro. Targeted at oligonucleotide CDMOs and biotech manufacturers.
- OligoNavigator® Pro Fully automated large-scale oligonucleotide synthesizer covering 10 mmol to 5 mol per batch, enabling production of hundreds of kilos to tons annually. Features built-in heater/cooler (10–50°C), conductivity and UV/NIR monitoring, and supports both GMP and non-GMP grade synthesis. Targeted at oligonucleotide manufacturers and CDMOs.
- Columns and Accessories Proprietary stainless steel columns available in 6 sizes (6.25–200 mL volume) for solid-phase synthesis, along with amino acid and amidite containers compatible with 50 mL falcon tubes, 225 mL falcon tubes, and GL 45 threaded glass bottles. Sold alongside PeptiSystems synthesizer instruments.
- PeptiSoft® User-friendly synthesis management software designed specifically for peptide and oligonucleotide synthesis. Provides full control and monitoring over the synthesis process, real-time visualization of UV, pressure, temperature, conductivity and flow parameters, with 21 CFR Part 11 compliant features. Sold separately and bundled with PeptiSystems instruments.
Quantifiable outcome
- 50-90% reduction in synthesis time, completing peptide synthesis in 1-3 days instead of 3-4 weeks
- +6 more outcomes
Companies that use PeptiSystems
Customer profileNamed customers3 records
Segments3 records
Ideal customer profiles3 records
PeptiSystems technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Feature6 records
PeptiSystems partnerships and signals
Strategic signalPartnerships
Four partnerships are on record, tiered flagship and core.
- Asahi Kasei Bioprocess AmericaflagshipExclusive global partnership to develop an integrated peptide synthesis solution combining PeptiSystems' flow-through technology with AKBA's large-scale synthesis columns. Aims to improve efficiency, reduce changeover times, and support high-performance peptide manufacturing.
- ATG Service USAcoreSales and service partner for North and South America providing local support for PeptiSystems synthesizer instruments. Located in Providence, RI.
- GENECO Service ChinacoreSales and service partner for China providing distribution and support for PeptiSystems instruments in the Chinese market.
- BioZed Engineering Pvt LtdcoreSales and service partner for India providing distribution and support for PeptiSystems instruments in the Indian market.
Scale indicators6 records
Expansion highlights6 records
PeptiSystems competitors and assessment
Company assessmentDirect peers
- CEM Corporation: CEM is a direct competitor in peptide synthesis instruments, best known for its Liberty and Discover Bio microwave-assisted peptide synthesizers used by pharma and academic labs. PeptiSystems' flow-through column technology competes head-to-head with CEM's batch-based instruments on speed, purity, and scale-up.
- Gyros Protein Technologies: Gyros Protein Technologies (formerly Biotage peptide synthesis) sells peptide synthesis and purification instruments to pharma and CDMOs. Multiple PeptiSystems executives previously worked at Gyros, making it a closely watched former-employer competitor with overlapping customer base.
- Biotage: Biotage offers peptide synthesis workstations, reagents, and purification systems widely used in pharma R&D and manufacturing. It competes with PeptiSystems across both peptide synthesis and downstream workflows.
- CSBio: CSBio manufactures peptide synthesizers (CS936, CS146) and provides custom peptide synthesis services to pharmaceutical and biotech customers. It is a direct competitor in the large-scale peptide synthesizer market.
- AAPPTec: AAPPTec (American Peptide Company) provides peptide synthesis instruments, reagents, and custom peptide services to pharma and academic researchers. It competes with PeptiSystems in both lab-scale and production peptide synthesis.
- Activotec: Activotec offers peptide synthesis instruments and flow chemistry solutions, including the Activo-P11 synthesizer. It overlaps with PeptiSystems' flow-through synthesis approach and shares pharma and biotech customers.
- Asahi Kasei Bioprocess: Asahi Kasei Bioprocess is both an exclusive global partner and a competitor through its large-scale synthesis columns and bioprocess equipment. It serves the same peptide and oligonucleotide manufacturing customers with complementary hardware.
Broad incumbents
- Thermo Fisher Scientific: Thermo Fisher is a broad life sciences tools incumbent offering peptide and oligonucleotide synthesis reagents, instruments, and contract services. It does not focus on flow-through column synthesis but competes for the same pharma and CDMO budget allocations.
- Agilent Technologies: Agilent provides oligonucleotide synthesis columns, reagents, and analytical instruments used in therapeutic nucleic acid manufacturing. It is a broader incumbent competing with PeptiSystems' OligoNavigator product line in the nucleic acid synthesis market.
- LGC Biosearch Technologies: LGC Biosearch Technologies offers oligonucleotide synthesis reagents, columns, and instruments to pharma and CDMOs. It is a broader incumbent in the oligonucleotide manufacturing tools market where PeptiSystems' OligoNavigator products compete.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat5 records
Key risks6 records
Key highlights7 records
Customer concentration
PeptiSystems social profiles
Digital presencePeptiSystems financial estimates
Financial estimateRevenue estimate
Valuation estimate
PeptiSystems leadership team
Management profileNumber of profiles
Profiles19 records
PeptiSystems funding detail
Funding detailFunding overview
Funding rounds3 records
Investors4 records
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
PeptiSystems M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about PeptiSystems
What does PeptiSystems do?
PeptiSystems designs, manufactures, and supplies automated peptide and oligonucleotide synthesizer instruments based on proprietary flow-through column technology for solid-phase synthesis. The portfolio spans lab-scale process development (0.1 mmol) to large-scale GMP manufacturing (up to 10 mol per batch), and is targeted at pharmaceutical companies, CDMOs, and biotech firms producing peptide and oligonucleotide therapeutics. The instruments are paired with PeptiSoft synthesis management software and proprietary columns and consumables.
Is PeptiSystems a public or private company?
PeptiSystems is a private company. It is classified as venture growth investor backed and is currently operating.
When was PeptiSystems founded?
PeptiSystems was founded in 2014. It employs 1 to 10 people.
Where is PeptiSystems based?
PeptiSystems is headquartered in Uppsala, Sweden, in the Europe region.
How does PeptiSystems make money?
Four revenue lines are on record. Instrument Sales are the primary driver. The others are software (PeptiSoft), accessories and Consumables and installation and Qualification Services.
Who are PeptiSystems's main competitors?
Direct peers on record are CEM Corporation, Gyros Protein Technologies, Biotage, CSBio, AAPPTec, Activotec and Asahi Kasei Bioprocess. Broad incumbents are Thermo Fisher Scientific, Agilent Technologies and LGC Biosearch Technologies.
Does PeptiSystems have an API?
No public API is recorded for PeptiSystems.
What industry is PeptiSystems in?
PeptiSystems's product category is Peptide and Oligonucleotide Synthesis Instruments. Its primary akta.pro industry code is HLAGAHAL, GMP Scale-Up, Tech Transfer & Process Validation (PPQ), with a secondary code of HLAIALAD, CMC & Pharmaceutical Development (Formulation/Process/Analytical Development). Its NAICS code is 334516 and its SIC code is 3826.