What Biotage does

Biotage AB is a Swedish life science technology company founded in 1969 and headquartered in Uppsala, with a regional headquarters in Boston. The company develops and sells instruments, proprietary consumables, and services for separation and purification workflows used in drug discovery, development, and analytical testing. Its offering spans five interconnected categories — synthesis (microwave synthesizers, peptide synthesizers including Initiator+, Initiator Alstra, and Syro), purification (flash chromatography systems such as Selekt and Isolera One, automated workstations, plasmid purification), evaporation (TurboVap and V-10 Touch systems), sample extraction and clean-up (bead-mill homogenizers, SPE workstations, ISOLUTE and EVOLUTE cartridges, QuEChERS products), and biomolecule purification (PhyPrep plasmid purification, PhyTip columns). The company also offers a custom oligonucleotide synthesis service.

Biotage's business model is a hybrid razor/blade: instrument sales (Biotage Selekt, Initiator+, Extrahera, PhyPrep, Lysera, TurboVap, Horizon 5000) generate one-time revenue, while proprietary consumables — ISOLUTE and EVOLUTE SPE cartridges, Sfär and Rening flash columns, PhyTip columns, ISOLUTE QuEChERS tubes and cSPE cartridges, supported reagents — produce recurring revenue tied to the installed base. Service revenue comes from custom oligonucleotide synthesis and, following the Astrea Bioseparations acquisition (2023), chromatography consumables for bioprocessing. Go-to-market is direct enterprise sales for instruments (quote-based pricing) combined with a self-service e-commerce storefront for accessories and consumables, supported by an extensive application-note and webinar library for product-led demand generation. Customers span pharmaceutical and biotech companies, food-safety and environmental testing laboratories, clinical and forensic labs, gene-therapy and vaccine developers, and academic and government research institutions.

The company is publicly traded in Sweden (AB designation) and has pursued an active acquisition strategy — Horizon Technology (2018), PhyNexus (2018), ATDBio (2021), Astrea Bioseparations (2023), and DPX Technologies (January 2025) — to expand its consumables franchise, enter bioprocessing, and broaden its sample-preparation footprint. Leadership includes Tomas Blomquist as CEO & President and Lars Bäckman as Chief Legal Officer.

Name

Biotage

Legal name

Biotage AB

Website

https://biotage.com

Company type

Public

Founded year

1969

Operating status

Operating

Headcount range

501–1,000 employees

Short description

Biotage AB is a Swedish life science technology company that develops and sells instruments, proprietary consumables, and services for separation and purification workflows serving pharmaceutical, biotech, food-safety, environmental, clinical, and academic laboratories worldwide.

Ownership category

akta.pro rank

Product category

Life Sciences Laboratory Instruments and Consumables

NAICS

Analytical Laboratory Instrument Manufacturing (334516)

SIC

Laboratory Analytical Instruments (3826)

akta.pro primary industry

Molecular Biology & Genomics Instruments (PCR/qPCR, Sequencing, Microarrays) (HLAGAIAF)

Keywords

• Sample preparation instruments
• Flash chromatography systems
• Peptide synthesis equipment
• Solid phase extraction consumables
• Plasmid purification systems

Headquarters

HQ city

Uppsala

HQ country

Sweden

HQ region

Europe

Offices2 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Personnel, Operations, Technology or R&D, Supply Chain, Marketing or Sales, Infrastructure

Revenue model

1. Scientific Instruments and Systems: Sale of chromatography systems, peptide synthesizers, sample preparation workstations, and evaporation systems. Instruments include Biotage Selekt, Initiator+, Extrahera, PhyPrep, Lysera, TurboVap, and related platforms. Revenue is one-time with recurring opportunities from accessories and upgrades.
2. Consumables and Disposables: High-margin consumables including ISOLUTE and EVOLUTE SPE cartridges, QuEChERS products, flash chromatography columns, frits, collection plates, and specialized plates. These form recurring revenue streams as customers repeatedly purchase consumables for their instruments.
3. Oligonucleotide Synthesis Service: Service offering for custom oligonucleotide synthesis as a value-added service complementing their synthesis equipment.
4. Bioprocessing Solutions: Through acquisition of Astrea Bioseparations, Biotage expands into chromatography solutions for biomanufacturing, adding higher-margin consumables for the bioprocessing segment.

Pricing tiers

Go-to-market motion3 records

Distribution channels2 records

Marketing channels7 records

Core offering

Biotage develops, manufactures, and sells scientific instruments and proprietary consumables used by laboratories for sample preparation, synthesis, purification, and evaporation workflows in drug discovery, development, and analytical testing. Its offering includes flash chromatography and peptide synthesis systems, automated SPE/SLE workstations, plasmid and protein purification platforms, solvent evaporators, bead mill homogenizers, and a large catalog of ISOLUTE/EVOLUTE SPE cartridges, QuEChERS products, and prepacked chromatography columns. It complements these with a custom oligonucleotide synthesis service.

Product overview

Biotage is a life sciences company offering a comprehensive portfolio of laboratory instruments and consumables for drug discovery, development, and analytical testing. The product portfolio spans five interconnected categories: Synthesis (including Biotage® Initiator+ microwave synthesizer, Biotage® Initiator Alstra peptide synthesizer, Syro parallel peptide synthesizers, and solid supported reagents); Purification (comprising Biotage® Selekt and Isolera™ One flash chromatography systems, Biotage® Extrahera™ automated workstations for peptide purification, and prepacked columns including Sfär Silica and Sfär C18 Duo); Evaporation (including TurboVap® series evaporators, Biotage® V-10 Touch vial evaporator, and Speed-Vap® systems); Sample Extraction and Clean-up (featuring Biotage® Lysera bead mill homogenizer, Biotage® PrepXpert-8 and Extrahera™ sample preparation workstations, solid-phase extraction cartridges and plates under the ISOLUTE® and EVOLUTE® brands, ISOLUTE® QuEChERS and ISOLUTE® cSPE products for food safety testing); and Biomolecule Purification (including Biotage® PhyPrep automated plasmid purification system and PhyTip® columns for protein and biomolecule purification). The platform architecture enables end-to-end workflows from synthesis through purification to analysis, with reusable instrument systems supported by a comprehensive range of proprietary consumables.

Differentiator

Problem solved

Functional benefit

Brands

• ISOLUTE: Brand for SPE cartridges, QuEChERS products, and extraction/solid-phase extraction solutions
• EVOLUTE
• Biotage Extrahera
• Biotage Selekt
• Biotage Initiator
• TurboVap
• Biotage PhyPrep
• Biotage Lysera
• Biotage VacMaster
• Biotage PRESSURE+
• Syro
• PhyTip

Products and services

• Biotage Initiator+ Microwave Synthesizer Microwave synthesizer for organic synthesis applications in pharmaceutical and chemical research laboratories.
• Biotage Initiator Alstra Peptide Synthesizer Peptide synthesizer designed for automated Fmoc-based solid-phase peptide synthesis.
• Syro I and II Parallel Peptide Synthesizers Parallel peptide synthesizers for high-throughput automated peptide synthesis.
• Biotage Selekt Flash Chromatography System Flash chromatography system for organic and peptide purification in laboratory settings.
• Isolera One Flash Chromatography System Flash chromatography system for small to medium-scale organic purification.
• Biotage Flash 400 Large-Scale Flash Chromatography System Large-scale flash chromatography system for industrial and pilot-plant purification.
• Biotage Flash 75 and 150 Large-Scale Flash Chromatography Systems Large-scale flash chromatography systems for industrial purification applications.
• Biotage Extrahera Classic Sample Preparation Workstation Multi-format automated sample preparation workstation for processing plates and cartridges, including parallel peptide purification.
• Biotage Extrahera LV-200 Sample Preparation Workstation Automated low-volume sample preparation workstation with precision dispensing and GLP compliance.
• Biotage Extrahera HV-5000 Sample Preparation Workstation High-volume automated sample preparation workstation with SMART pipetting for processing larger sample volumes.
• Biotage Horizon 5000 Disk Extraction System Disk extraction system for high-throughput solid-phase extraction processing.
• Biotage PrepXpert-8 Sample Preparation System Automated sample preparation system providing precision, flexibility, and throughput for modern laboratory workflows.
• Biotage PRESSURE+ Positive Pressure Manifold Positive pressure manifold providing consistent, uniform flow for processing 96-well plates and cartridge formats.
• Biotage VacMaster Vacuum Manifold Vacuum manifold system for SPE and filtration processing across formats from single disk to 96-well plates.
• Biotage PhyPrep Plasmid Purification System Automated plasmid purification system delivering high-purity, low-endotoxin, transfection-grade DNA across Maxi, Mega, and Giga scales.
• ME System Protein Purification System Protein purification system for automated biomolecule separation and purification workflows.
• TurboVap Automated Solvent Evaporation System Automated solvent evaporation system available in LV, II, EH, and P+ configurations for nitrogen evaporation in sample preparation.
• TurboVap 96 Dual Nitrogen Evaporator Dual-format automated nitrogen evaporator for high-throughput sample concentration.
• Biotage SPE Dry Sample Concentrator Sample concentrator for automated solvent evaporation and sample drying.
• Biotage V-10 Touch Vial Evaporation System Vial evaporation system for automated solvent removal from vial-based samples.
• Speed-Vap Solvent Evaporation System Solvent evaporation system for rapid sample concentration.
• DryDisk Solvent Drying System Solvent drying system using membrane technology for efficient solvent recovery and sample preparation.
• Biotage Lysera Bead Mill Homogenizer Bead mill homogenizer for automated grinding, lysing, and homogenizing of biological, food, and environmental samples.
• Biotage Sfär Silica Flash Chromatography Column Flash chromatography column packed with spherical silica sorbent for improved separation performance.
• Biotage Sfär C18 Duo Flash Chromatography Column Reversed-phase flash chromatography column for medium-polarity compound purification.
• Biotage Sfär Bio C18 Duo Flash Chromatography Column Bio-specific reversed-phase flash chromatography column for biomolecule purification.
• Biotage Rening Flash Chromatography Column Flash chromatography column with advanced silica for enhanced purification performance.
• ISOLUTE SCX-2 SPE Cartridges and Plates Strong cation exchange SPE cartridges for extraction of basic compounds from aqueous and non-aqueous matrices.
• ISOLUTE PE-AX SPE Cartridges Mixed-mode SPE cartridges combining reversed-phase and anion exchange properties for polar compound extraction.
• ISOLUTE SLE+ Supported Liquid Extraction Cartridges and Plates Supported liquid extraction plates and cartridges using load-wait-elute procedure for extraction of analytes from biological fluids.
• ISOLUTE QuEChERS Extraction and Clean-up Tubes Pre-weighed extraction and clean-up tubes conforming to AOAC and EN methodologies for pesticide residue analysis in food samples.
• ISOLUTE cSPE for QuEChERS Clean-up Cartridges Pre-packed cartridges designed to replace traditional dSPE step in QuEChERS procedures, enabling flow-through clean-up of pesticide residues in fruit and vegetables.
• ISOLUTE Myco SPE Columns Mycotoxin-specific SPE columns for extraction of patulin and other mycotoxins from foodstuffs.
• ISOLUTE PLD+ Protein and Phospholipid Removal Cartridges and Plates Protein and phospholipid removal cartridges and plates for biological sample clean-up.
• ISOLUTE PLD+ for PFAS Cartridges and Plates PFAS-specific protein and phospholipid removal cartridges for PFAS analysis in biological matrices.
• ISOLUTE PPT+ Protein Precipitation Plates Protein precipitation plates for simplified sample preparation in bioanalytical workflows.
• ISOLUTE FILTER+ Filtration Plate High-performance filtration plates for filtration of biological samples prior to UPLC-MS/MS analysis.
• EVOLUTE EXPRESS ABN SPE Cartridges and Plates Enhanced performance SPE cartridges for accelerated bioanalytical sample preparation.
• EVOLUTE PFAS SPE Cartridge PFAS-specific SPE cartridge for environmental and food PFAS analysis.
• Biotage Mikro Microelution SPE Plate Microelution SPE plate for minimal sample volume applications in bioanalytical testing.
• Biotage Oligo SPE Solid-Phase Extraction Plate Solid-phase extraction plate designed for oligonucleotide sample preparation and cleanup.
• PhyTip Columns and Kits for Biomolecule Purification Automated purification columns including gel filtration, glutathione, IMAC, and AAV formats for biomolecule purification workflows.
• Biotage PS-TBD Supported Reagent Supported reagent for nucleophilic catalysis and other organic synthesis transformations.
• Biotage PS-Triphenylphosphine Supported Reagent Polymer-supported triphenylphosphine for Mitsunobu reactions and other phosphine-mediated transformations.
• Oligonucleotide Synthesis Service Custom oligonucleotide synthesis service for research-grade synthetic DNA and RNA oligonucleotides.

Quantifiable outcome

• Cut prep time by up to 40% with automated plasmid purification
• +5 more outcomes

Named customers7 records

Segments5 records

Ideal customer profiles6 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature8 records

Partnerships

Four partnerships are on record, tiered core, major and minor.

• DPX TechnologiescoreStrategic or Co-development Partner · 5 January 2025Biotage acquired DPX Technologies, an industry-leading Pipette Tip Technology and Applications company. This acquisition enables Biotage to provide industry-leading Pipette Tip Technology and Applications, expanding their sample preparation portfolio.
• Gamma BiosciencesmajorStrategic or Co-development Partner · 15 February 2023Biotage announced agreement to acquire Astrea Bioseparations from Gamma Biosciences. Astrea provides chromatography solutions for biomanufacturing. The acquisition aims to expand Biotage's presence in the bioprocessing segment and boost revenue streams through new products and higher-margin consumables. Deal pending shareholder approval and customary closing conditions.
• Omni InternationalminorStrategic or Co-development PartnerCollaboration between Biotage and Omni International application laboratories for development and validation of bead mill homogenization methods. Application notes developed jointly to evaluate effectiveness of Biotage Lysera for pesticide extraction using QuEChERS methods.
• KTH Royal Institute of TechnologyminorStrategic or Co-development PartnerKTH researchers collaborated with Biotage to present a streamlined automated plasmid purification process that reduces labor time and increases titers for AAV production using Biotage PhyPrep.

Scale indicators10 records

Recent moves6 records

Expansion highlights5 records

Direct peers

• Phenomenex: Phenomenex (a Danaher operating company) supplies SPE cartridges, flash chromatography columns, and sample preparation consumables directly overlapping with Biotage's ISOLUTE/EVOLUTE and Sfär product lines for pharma, food safety, and environmental labs.
• Restek Corporation: Restek manufactures chromatography columns, sample preparation products (SPE, QuEChERS), and reference standards serving the same food safety, environmental, and clinical research customers as Biotage.

Broad incumbents

• Agilent Technologies: Agilent is a large incumbent in analytical instruments and chromatography consumables, overlapping with Biotage in SPE workflows, flash chromatography, and mass-spec sample prep for pharma and food safety.
• Waters Corporation: Waters is a leader in LC chromatography, SPE (Oasis), and sample preparation workflows, directly competitive with Biotage's flash chromatography and SPE consumable offerings in pharma and bioanalysis.
• Shimadzu Scientific Instruments: Shimadzu supplies analytical instruments, peptide synthesizers, and chromatography systems; named alongside Biotage as a top-6 global peptide synthesizer manufacturer, competing head-on in pharma and academic labs.
• Thermo Fisher Scientific: Thermo Fisher offers a broad portfolio of lab instruments, SPE consumables, and sample preparation automation that overlaps with Biotage's instruments and ISOLUTE/EVOLUTE workflows in pharma and food safety.
• Cytiva (Danaher): Cytiva provides chromatography solutions for biomanufacturing, directly overlapping with Biotage's newly acquired Astrea Bioseparations bioprocessing franchise and plasmid/AAV purification offerings.
• Sartorius AG: Sartorius supplies bioprocess chromatography, filtration, and fluid management solutions for biologics manufacturing, competing in the higher-margin bioprocessing segment Biotage entered via Astrea.
• Bio-Rad Laboratories: Bio-Rad provides life science research and clinical diagnostics instruments plus chromatography and protein purification products, overlapping with Biotage's protein purification, SPE, and laboratory workflow offerings.

Emerging players

• Repligen Corporation: Repligen specializes in bioprocessing chromatography and filtration consumables for biologics manufacturing, an emerging peer as Biotage expands into bioprocess via its Astrea acquisition.

Market position

Weaknesses4 records

Competitive moat5 records

Key risks5 records

Key highlights6 records

Customer concentration

• YouTubeyoutube.com/@biotagecompany
• Facebookfacebook.com/BiotageAB
• LinkedInlinkedin.com/company/biotage
• Xx.com/Biotage

Revenue estimate

Valuation estimate

Number of profiles

Profiles2 records

Subsidiaries2 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A4 records

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Biotage