What Endo Tools Therapeutics does

Endo Tools Therapeutics S.A. (ETT) is a Belgian medical device company founded in 2008 and headquartered in Gosselies, Belgium, with a U.S. subsidiary in Garden City, New York. The company develops the endomina® system, an endoscopic triangulation platform that attaches to standard endoscopes and provides a bendable therapeutic channel moving independently from the endoscope axis, combined with TAPES (Tissue Approximation and Piercing Suture) suturing instruments. This enables gastroenterologists to perform incisionless gastrointestinal suturing through a natural orifice (the mouth), comparable to laparoscopic interventions but without external incisions. The next-generation endomina® EZFuse™ system received FDA 510(k) clearance on March 17, 2026, with single-movement tightening that reduces total procedure time by up to 50% versus the prior generation.

ETT's core customers are gastroenterologists and endoscopists at hospitals and ambulatory surgery centers, with the primary use cases being endoscopic gastroplasty for obesity treatment and soft tissue approximation in the gastrointestinal tract. Documented clinical outcomes include a serious adverse event rate below 1%, an average procedure time of approximately 25 minutes, and 42.7% excess weight loss at 12 months post-procedure for the obesity indication. Over 1,500 procedures have been performed across Europe, select Middle East countries, and the United States.

The company's revenue model is primarily hardware sales of the triangulation platform and TAPES suture devices to healthcare facilities on a quote-based model, supplemented by professional training and certification services for physicians and nurses. Distribution occurs through direct sales with Field Clinical Specialists deployed in Italy, Spain, France, and Belgium, and through Dawa Medical LLC as the initial U.S. importer. The company has raised approximately $18.7 million across four funding rounds between 2013 and 2021, with support from the Walloon Region (DGO6) and investors including White Fund, Chagral Invest, Epimède, and SFPI-FPIM. Both devices are CE marked in Europe and FDA cleared in the U.S.

Name

Endo Tools Therapeutics

Legal name

Endo Tools Therapeutics S.A.

Website

https://endotools.be

Company type

Private

Founded year

2008

Operating status

Operating

Headcount range

11–50 employees

Short description

Endo Tools Therapeutics is a Belgian medical device company developing the endomina® endoscopic triangulation and suturing system for incisionless gastrointestinal procedures. It serves gastroenterologists and hospitals in Europe, the Middle East, and the U.S., with primary applications in obesity treatment and soft tissue approximation.

Ownership category

akta.pro rank

Product category

Endoscopic Medical Devices

NAICS

Surgical and Medical Instrument Manufacturing (339112), Surgical Appliance and Supplies Manufacturing (339113)

SIC

Surgical & Medical Instruments & Apparatus (3841)

akta.pro primary industry

Endoscopic Therapeutic & Access Devices (Trocars, dilators, biopsy/ablation tools) (HLAHADAN)

akta.pro secondary industries

Endoscopy Systems & Accessories (Scopes, Cameras, Light Sources, Insufflation) (HLAHADAB), Advanced Endoscopy (ERCP/EUS/Interventional) (HLAKAEAC)

Keywords

• Endoscopic suturing devices
• Medical device manufacturing
• Incisionless gastroplasty
• Endoscopic tissue approximation
• Gastroenterology medical devices

Headquarters

HQ city

Gosselies

HQ country

Belgium

HQ region

Europe

Offices2 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Technology or R&D, Supply Chain, Personnel, Marketing or Sales, Operations

Revenue model

1. Medical Device Sales: Sale of endoscopic suturing devices (endomina system) to healthcare facilities including hospitals and ambulatory surgery centers. The company sells both the triangulation platform and suturing units (TAPES).
2. Professional Training Services: Best-in-class training programs for healthcare professionals including physicians and nurses, with structured training leading to certification for endoscopic gastroplasty procedures.

Go-to-market motion2 records

Distribution channels3 records

Marketing channels5 records

Core offering

Endo Tools Therapeutics develops and manufactures the endomina system, an endoscopic triangulation platform combined with TAPES (Tissue Piercing and Approximation) suturing units, enabling gastroenterologists to perform incisionless gastrointestinal suturing through natural orifices. The next-generation endomina EZFuse system provides enhanced suturing efficiency with single-movement tightening and securing. The devices are CE marked for endoscopic gastroplasty in Europe and FDA 510(k) cleared for soft tissue approximation in the United States, used in procedures for obesity treatment and gastrointestinal tissue approximation.

Product overview

Endo Tools Therapeutics offers a portfolio of advanced endoscopic medical devices for incisionless gastrointestinal procedures. The core offering consists of the endomina® system, comprising a triangulation platform and TAPES suturing unit, which together enable endoscopists to perform suturing similar to laparoscopic interventions through a natural orifice (the mouth). The next-generation endomina® EZFuse™ system enhances this platform with improved suturing efficiency and workflow. The devices are CE marked for endoscopic gastroplasty in Europe and FDA cleared for tissue approximation in the United States, with over 1,500 procedures performed globally.

Differentiator

Problem solved

Functional benefit

Products and services

• endomina® triangulation platform A triangulation platform that attaches to standard endoscopes, providing a bendable therapeutic channel that moves independently from the endoscope. It is the only triangulation technology that can be assembled and disassembled inside the stomach, enabling enhanced maneuverability and degrees of freedom comparable to a surgeon's hands. Designed for gastroenterologists performing endoscopic gastrointestinal procedures.
• TAPES (Tissue Piercing and Approximation Suture) A suturing unit used with the endomina triangulation platform for tissue piercing and approximation. Enables full-thickness suturing for creating plications and stitching tissue pairs together for endoscopic gastroplasty procedures. Used by gastroenterologists for gastrointestinal tissue approximation.
• endomina® EZFuse™ system Next-generation endoscopic suturing system combining the endomina triangulation platform with an enhanced suture device. Features a single-movement tightening and securing mechanism delivering faster suturing with up to 50% reduction in total procedure time. FDA 510(k) cleared for soft tissue approximation in the GI tract. Designed for gastroenterologists performing incisionless gastrointestinal procedures.

Quantifiable outcome

• Total procedure time reduction up to 50% with EZFuse system
• +3 more outcomes

Named customers1 record

Segments3 records

Ideal customer profiles2 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature3 records

Scale indicators5 records

Recent moves6 records

Expansion highlights5 records

Direct peers

• Apollo Endosurgery (Boston Scientific): Acquired by Boston Scientific in 2023, Apollo's OverStitch endoscopic suturing system is the closest direct competitor to endomina, used by gastroenterologists for tissue approximation and bariatric endoscopic procedures in the same US and European call points.
• USGI Medical: Develops incisionless endoscopic suturing and tissue-anchoring devices (g-Cath, g-Lix) for GI procedures including endoscopic gastroplasty — directly overlapping with endomina's therapeutic focus and target physician base.
• Medigus: Israel-based developer of the MUSE (Medigus Ultrasonic Surgical Endostapler) system for incisionless fundoplication and related endoscopic procedures — competing with endomina in the same transoral, incisionless GI surgery niche.

Broad incumbents

• Olympus: Global leader in endoscopy systems and therapeutic accessories; sells the endoscopes that endomina attaches to and offers competing therapeutic devices targeting the same gastroenterology customers.
• Pentax Medical (HOYA): Manufactures flexible endoscopes and therapeutic accessories used by the same gastroenterology call points; potential future overlap if Pentax expands into therapeutic endoscopic suturing.
• Fujifilm Healthcare: Major endoscopy systems and accessories competitor serving the same gastroenterology hospitals and ASCs where endomina is positioned.
• Karl Storz: Established endoscopy and minimally invasive surgery vendor with therapeutic accessories and integration partnerships relevant to ETT's gastroenterology customers.
• Ethicon (Johnson & Johnson): Surgical endoscopy and suturing franchise with deep gastroenterology relationships; relevant incumbent competitor for hospital and ASC contracts.
• Ambu: Single-use endoscopy pioneer with GI, pulmonology, and ENT presence; key customer/employer reference (CCO Kevin Krose previously VP Sales at Ambu) and broader competitive set in flexible endoscopy.

Others

• Boston Scientific: Major medtech incumbent with broad GI/endoscopy portfolio (including Apollo Endosurgery's OverStitch) and a large US sales force targeting the same gastroenterology accounts as ETT.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat4 records

Key risks6 records

Key highlights6 records

Customer concentration

• LinkedInlinkedin.com/company/endo-tools-therapeutics
• Xx.com/endotools

Compliance2 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles6 records

Funding overview

Funding rounds5 records

Investors6 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Endo Tools Therapeutics