CryoCloud
CryoCloud is a Dutch SaaS company offering cloud-based cryo-EM and X-ray crystallography data analysis for protein structure determination. It serves academic researchers, cryo-EM facilities, biotechs, CROs, and pharma clients across 25+ countries via a browser-based platform with proprietary GPU-accelerated algorithms and automated end-to-end workflows.
- Company typePrivate
- Founded2021
- HeadquartersUtrecht, Netherlands
- Headcount1–10
- GTM typeB2B
- OfferingSoftware
CryoCloud firmographics
Firmographics- Name
- CryoCloud
- Legal name
- CryoCloud B.V.
- Website
- https://cryocloud.io
- Company type
- Private
- Founded year
- 2021
- Operating status
- Operating
- Headcount range
- 1–10 employees
- Short description
- CryoCloud is a Dutch SaaS company offering cloud-based cryo-EM and X-ray crystallography data analysis for protein structure determination. It serves academic researchers, cryo-EM facilities, biotechs, CROs, and pharma clients across 25+ countries via a browser-based platform with proprietary GPU-accelerated algorithms and automated end-to-end workflows.
- Ownership category
- akta.pro rank
CryoCloud industry classification
Industry- Product category
- Cryo-EM Data Analysis Software
- NAICS
- Computer Systems Design and Related Services (5415)
- SIC
- Services-Prepackaged Software (7372)
- akta.pro primary industry
- Sample Preparation, Storage & Cryogenics (Freezers, Cryovials, Cryostats) (HLAGAIAJ)
Keywords
Where CryoCloud is headquartered
LocationHeadquarters
- HQ city
- Utrecht
- HQ country
- Netherlands
- HQ region
- Europe
Offices1 record
Markets served
CryoCloud business model
Business model- GTM type
- B2B
- Offering type
- Software
- Cost components
- Infrastructure, Technology or R&D, Personnel, Marketing or Sales, Operations
Revenue model
- SaaS Platform Subscription: CryoCloud operates as a biotech SaaS startup offering cloud-based cryo-EM data analysis on a subscription basis. Users pay for compute hours and storage usage on a flexible, pay-as-you-use model with plans starting from $800 per year. The platform includes free academic licenses with compute and storage quotas.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| Freemium | Monthly | Free Plan for Academia - Ideal for students and early-career researchers |
| Subscription | Annual | 30-Day Evaluation Trial - For organizations actively evaluating CryoCloud for purchase |
| Subscription | Annual | Standard Subscription - Starting price point |
Go-to-market motion2 records
Distribution channels3 records
Marketing channels7 records
CryoCloud product offering
Product offeringCore offering
CryoCloud provides a cloud-native SaaS platform for cryo-electron microscopy (cryo-EM) data analysis and high-resolution 3D protein structure determination. The platform offers proprietary ML-based algorithms for particle picking, GPU-accelerated motion correction, and automated end-to-end processing workflows, eliminating the need for on-premise HPC infrastructure. It is sold on a usage-based subscription model starting at $800 per year, with a free academic license tier and a 30-day evaluation trial.
Product overview
CryoCloud is a cloud-native SaaS biotech platform for cryo-EM data analysis, offering a unified platform with proprietary algorithms and streamlined workflows for determining 3D protein structures from data collection to high-resolution structure determination. The core CryoCloud Platform handles end-to-end processing including motion correction, particle picking, classification, and 3D refinement. Key add-on modules include CryoCloud MotionCorr (in-house GPU-accelerated motion correction), CC Up (stand-alone uploader for live data transfer), and X-ray Crystallography Workflows. The platform integrates a comprehensive suite of open-source scientific software (RELION, AlphaFold, ColabFold, Topaz, cryoDRGN, DeepEMhancer, and others) accessible within the web application. CryoCloud supports both cryo-EM single-particle analysis and X-ray crystallography workflows, serving academia, facilities, biotech, CROs, and pharma customers across 25+ countries.
Differentiator
Problem solved
Functional benefit
Products and services
- CryoCloud Platform Cloud-native SaaS platform for cryo-EM data analysis providing end-to-end workflows from data upload to high-resolution 3D protein structure determination, featuring proprietary algorithms, GPU acceleration, automated processing pipelines, and ISO 27001-certified security. Used by academic researchers, cryo-EM facilities, biotech companies, CROs, and pharmaceutical firms.
- Free Academic License Free tier of the CryoCloud platform designed for students and early-career researchers in academia, including 3 compute hours per month and 500 GB of storage for exploring features and running small datasets.
- Standard Subscription Plan Paid subscription tier of the CryoCloud platform starting from $800 per year, including instant setup, 30-day free trial option, access to dozens of GPUs and petabytes of storage on demand with flexible pay-as-you-use pricing.
- X-ray Crystallography Workflows X-ray Crystallography data processing pipeline integrated into CryoCloud, supporting automated XRC workflows with scalable parallel analyses using Global Phasing Pipedream, extending the platform beyond cryo-EM.
- CC Up (CryoCloud Uploader) Stand-alone OS-agnostic desktop application for uploading cryo-EM data, supporting live upload during microscope sessions on Windows, Linux, and Mac, syncing directly with CryoCloud datasets.
Quantifiable outcome
- 4x faster motion correction performance compared to Relion's CPU implementation
- +5 more outcomes
Companies that use CryoCloud
Customer profileNamed customers1 record
Segments5 records
Ideal customer profiles4 records
CryoCloud technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Integration16 records
AI capability6 records
Feature6 records
CryoCloud partnerships and signals
Strategic signalScale indicators4 records
Recent moves6 records
Expansion highlights6 records
CryoCloud competitors and assessment
Company assessmentBroad incumbents
- Schrödinger: Public computational chemistry and molecular simulation platform serving pharma/biotech drug discovery. Overlaps with CryoCloud in structural biology and structure-based drug design customers but operates much more broadly across molecular simulation, not narrowly in cryo-EM data processing.
- Benchling: Cloud-based R&D platform for biotech, serving lab data management and molecular biology workflows. Comparable SaaS model and biotech customer base, but much broader platform scope than CryoCloud's cryo-EM specialization.
- Dotmatics: Scientific R&D informatics platform for life sciences, providing data management and analytics across pharma and biotech R&D. Adjacent SaaS model and customer base but addresses broader R&D workflows rather than cryo-EM specifically.
- TetraScience: Cloud-native scientific data and AI platform for life sciences R&D, working with pharma/biotech on data lakes and AI workloads. Adjacent in life-sciences SaaS and pharma customer base, but serves broader lab-data rather than cryo-EM analysis.
- OpenEye / Cadence Molecular Sciences: Computational chemistry and molecular modeling SaaS platform for pharma drug discovery. Comparable SaaS economics and pharma/biotech customer base, though focused on ligand design rather than cryo-EM data analysis.
- Amazon Web Services HealthOmics: AWS managed cloud service for genomics and life-sciences data processing. Comparable cloud-based life-sciences data-processing model with enterprise scale; a potential competitive threat if AWS adds cryo-EM pipelines natively.
Direct peers
- Structura Biotechnology: Maker of cryoSPARC, the dominant cryo-EM single-particle analysis software used by most academic and pharma cryo-EM facilities. Closest direct competitor to CryoCloud in cloud-and-desktop cryo-EM processing, serving overlapping academia, facility, and pharma customers.
- Phenix / Adams Lab: Open-source computational crystallography and cryo-EM software suite widely adopted in structural biology. Competes with CryoCloud for the same end users (academic and pharma structural biologists) using a free, downloadable alternative model.
Emerging players
- BioSymetrics: AI-driven computational drug discovery platform serving pharma and biotech. Comparable SaaS-for-drug-discovery model targeting overlapping early-stage biotech and CRO customers, though focuses on phenotypic and ML prediction rather than cryo-EM.
- Google DeepMind (AlphaFold team): Creator of AlphaFold protein structure prediction, integrated into CryoCloud's platform. Not a direct cryo-EM competitor today, but a structural-biology frontier force that could either complement or partially substitute for experimental cryo-EM over time.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat5 records
Key risks5 records
Key highlights7 records
Customer concentration
CryoCloud social profiles
Digital presenceCryoCloud compliance and trust
Trust signalCompliance1 record
CryoCloud financial estimates
Financial estimateRevenue estimate
Valuation estimate
CryoCloud leadership team
Management profileNumber of profiles
Profiles4 records
CryoCloud funding detail
Funding detailFunding overview
Funding rounds2 records
Investors4 records
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
CryoCloud M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about CryoCloud
What does CryoCloud do?
CryoCloud provides a cloud-native SaaS platform for cryo-electron microscopy (cryo-EM) data analysis and high-resolution 3D protein structure determination. The platform offers proprietary ML-based algorithms for particle picking, GPU-accelerated motion correction, and automated end-to-end processing workflows, eliminating the need for on-premise HPC infrastructure. It is sold on a usage-based subscription model starting at $800 per year, with a free academic license tier and a 30-day evaluation trial.
Is CryoCloud a public or private company?
CryoCloud is a private company. It is classified as venture growth investor backed and is currently operating.
When was CryoCloud founded?
CryoCloud was founded in 2021. It employs 1 to 10 people.
Where is CryoCloud based?
CryoCloud is headquartered in Utrecht, Netherlands, in the Europe region.
How does CryoCloud make money?
One revenue line is on record: saaS Platform Subscription.
Who are CryoCloud's main competitors?
Broad incumbents on record are Schrödinger, Benchling, Dotmatics, TetraScience, OpenEye / Cadence Molecular Sciences and Amazon Web Services HealthOmics. Direct peers are Structura Biotechnology and Phenix / Adams Lab. Emerging players are BioSymetrics and Google DeepMind (AlphaFold team).
Does CryoCloud have an API?
No public API is recorded for CryoCloud.
What industry is CryoCloud in?
CryoCloud's product category is Cryo-EM Data Analysis Software. Its primary akta.pro industry code is HLAGAIAJ, Sample Preparation, Storage & Cryogenics (Freezers, Cryovials, Cryostats). Its NAICS code is 5415 and its SIC code is 7372.