What Leinco Technologies does

Leinco Technologies is a privately held biotechnology company founded in 1992 and headquartered in Fenton (St. Louis), Missouri, specializing in the manufacture of early discovery research products — primarily monoclonal and polyclonal antibodies, recombinant proteins, cytokines, ELISA kits, and IVD raw materials — alongside custom CDMO services for life science researchers, IVD manufacturers, and biopharmaceutical companies. The company's core technology stack includes proprietary hybridoma development (mouse, rat, rabbit), mammalian transient expression using HEK293 and CHO systems, BriClone/BriClone-SF hybridoma cloning platforms, and purification methods spanning Protein A/G affinity and ion-exchange chromatography. It operates from an ISO 9001:2015 and ISO 13485:2016 certified facility under cGMP conditions, supporting production of in vivo functional grade antibodies (PLATINUM™ and GOLD™), custom conjugations (FITC, PE, biotin, HRP, NIR-SHIELD™), and a growing portfolio in spatial biology (PhenoCycler-Fusion/CODEX® validated and barcoded antibodies).

The company generates revenue through three streams: catalog antibody and protein product sales (publicly listed unit pricing from ~$75 to $3,375 with tiered bulk discounts and a 'mAb Advantage Pricing' program), quote-based custom CDMO services spanning hybridoma development through cGMP manufacturing, and IVD raw materials supply (matched pair antibodies, antigens, conjugates, assay buffers). GTM is primarily direct-to-customer via leinco.com e-commerce with phone/email support, supplemented by a global network of authorized distributors. Leinco is backed by private equity firm Ampersand Capital Partners, completed acquisitions of QED Biosciences and the Genovis antibody business in 2024, and announced a strategic collaboration with CellCarta in April 2026 to integrate its antibody portfolio into immuno-oncology proteomics workflows.

Name

Leinco Technologies

Legal name

Leinco Technologies, Inc.

Website

https://leinco.com

Company type

Private

Founded year

1992

Operating status

Operating

Headcount range

51–100 employees

Short description

Leinco Technologies is a St. Louis-based, PE-backed manufacturer of antibodies, recombinant proteins, and IVD raw materials founded in 1992, serving life science researchers, IVD manufacturers, and biopharmaceutical companies with catalog products and custom CDMO services.

Ownership category

akta.pro rank

Product category

Life Science Research Reagents (Antibodies and Proteins)

NAICS

Biological Product (except Diagnostic) Manufacturing (325414)

SIC

In Vitro & In Vivo Diagnostic Substances (2835)

akta.pro primary industry

Reagents, Chemicals & Assay Kits (Buffers, Antibodies, ELISA, Enzymes) (HLAGAIAI)

Keywords

• Monoclonal antibodies
• Recombinant proteins
• Antibody manufacturing
• IVD raw materials
• Custom antibody services

Headquarters

HQ city

Fenton

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Personnel, Operations, Supply Chain, Technology or R&D, Infrastructure, Marketing or Sales

Revenue model

1. Catalog Antibody and Protein Products: Leinco generates revenue from the sale of catalog monoclonal and polyclonal antibodies, recombinant proteins, ELISA kits, assay buffers, and reagents. Products are sold in various sizes with tiered pricing (e.g., 1mg to 100mg quantities) at publicly listed prices. The company also offers conjugated formats (FITC, PE, biotin, HRP) and isotype controls.
2. Custom CDMO Services: Leinco provides contract development and manufacturing services including custom antibody development, monoclonal antibody manufacturing, recombinant protein production, cell banking, conjugation services, and immunoassay development. These services are quote-based and typically involve multi-step processes from planning through cGMP manufacturing.
3. IVD Raw Materials: Leinco supplies IVD antibodies, matched pair antibodies, antigens, and conjugates for use in diagnostic immunoassays including lateral flow tests and ELISA, positioned as raw materials for further manufacturing.

Pricing tiers

Go-to-market motion1 record

Distribution channels3 records

Marketing channels5 records

Core offering

Leinco Technologies manufactures and sells catalog monoclonal and polyclonal antibodies, recombinant proteins, cytokines, ELISA kits, IVD raw materials (matched pair antibodies, antigens, conjugates, assay buffers), and specialized research tools including PLATINUM™/GOLD™ functional grade antibodies and PhenoCycler-Fusion (CODEX)® validated antibodies. The company also provides custom CDMO services covering antibody development, mammalian protein production, conjugation, purification, cell banking, gene synthesis, and immunoassay development through cGMP manufacturing.

Product overview

Leinco Technologies is a biotechnology company founded in 1992 specializing in early discovery research products and custom manufacturing services for the life sciences and IVD markets. The company offers a comprehensive portfolio of antibodies (primary monoclonal, secondary, in vivo functional grade PLATINUM™ and GOLD™, isotype controls, chimeric mAbMods™, and biosimilars), recombinant proteins, cytokines, and ELISA kits. For diagnostics, Leinco provides IVD raw materials including matched pair antibodies, antigens, conjugates, and assay buffers. The portfolio also includes spatial biology products validated for PhenoCycler-Fusion (CODEX)® platforms, novel technologies like the ADAPT-3D Tissue Clearing Kit and NIR-SHIELD™ conjugation, and bispecific antibodies. Custom services span the entire development pipeline from gene synthesis, antibody development (hybridoma, B-cell sequencing, rabbit monoclonal), protein production (HEK293/CHO expression), conjugation services, purification, cell banking, through to immunoassay development and cGMP manufacturing. Products are manufactured in the company's ISO 9001:2015 and ISO 13485:2016 certified St. Louis, Missouri facility.

Differentiator

Problem solved

Functional benefit

Products and services

• Primary Monoclonal Antibodies Extensive range of primary monoclonal antibodies for research enabling scientists to generate reliable, publication-quality data across multiple applications including flow cytometry, IHC, Western Blot, ELISA, and functional studies. Intended for life science researchers.
• In Vivo Functional Grade Antibodies (PLATINUM™ and GOLD™) High-purity functional grade preclinical antibodies manufactured in animal-free facilities using in vitro protein-free cell culture techniques. PLATINUM™ grade features endotoxin levels <0.5 EU/mg and IDEXX IMPACT I pathogen testing; GOLD™ grade features endotoxin levels <1.0 EU/mg. Used by researchers for in vivo preclinical studies.
• Secondary Antibodies Secondary polyclonal antibodies and streptavidin products absorbed to minimize species cross-reactivity, optimally conjugated for assay-specific performance. Includes IgG Affinity Purified Antibodies, Normal Serums and Gamma Globulins, and Secondary Antibodies for Non-Human Primates. For research use.
• Isotype Control Antibodies Isotype-matched negative control antibodies for flow cytometry and in vivo studies, available in multiple formats including purified, conjugated (FITC, PE, APC, biotin, PerCP, DyLight conjugates), and functional grades. For research applications.
• mAbMods™ Chimeric Antibodies Engineered chimeric antibodies combining constant regions from one species with variable regions from another, designed for specific research applications requiring modified effector functions. Proprietary brand offered by Leinco Technologies.
• Biosimilar Antibodies High-quality recombinant human biosimilar antibodies for research use only, providing reliable tools to support therapeutic development and comparative studies.
• IVD Raw Materials (Matched Pair Antibodies, Antigens & Conjugates, Assay Buffers) High-quality, low cross-reactivity IVD antibodies for use in diagnostic immunoassays supporting disease detection, therapeutic monitoring, and drug screening. Includes Matched Pair Antibodies, Antigens & Conjugates, and Assay Buffers. Intended for IVD manufacturers and diagnostic kit developers.
• Recombinant Proteins, Growth Factors & Cytokines Ultra-pure recombinant proteins tested for optimal biological activity and reproducibility, including Type I & Type II Interferons, inflammatory cytokines, and ELISA kits. For research use.
• PhenoCycler-Fusion (CODEX)® Validated Antibodies Antibodies validated for use with the PhenoCycler-Fusion spatial biology platform, enabling multiplexed single-cell analysis of tissue samples through cyclic immunofluorescence imaging. For spatial biology researchers.
• PhenoCycler-Fusion (CODEX)® Barcoded Antibodies Barcoded antibodies for use with the PhenoCycler-Fusion workflow, allowing sequential staining and imaging of multiple targets on the same tissue section. For spatial biology researchers.
• ADAPT-3D Tissue Clearing Kit Novel tissue clearing technology for rapid whole-mount tissue labeling, enabling 3D visualization and analysis of intact tissue samples. For research applications.
• NIR-SHIELD™ Conjugation Products and Services Near-infrared fluorescent dye conjugation services and products for antibody labeling, enabling detection and imaging applications in the NIR spectrum. For research and diagnostic use.
• Bispecific Antibodies Dual-targeting therapeutic molecules for research applications, enabling simultaneous binding to two different antigens. For therapeutic discovery research.
• IHC Antibodies & Reagents Validated immunohistochemistry antibodies and reagents for precise protein visualization in tissue samples, supporting disease research and diagnostics on fresh frozen or formalin-fixed paraffin-embedded tissues.
• ELISA Kits Ready-to-use ELISA development kits and components for biomarker detection and quantification in research applications.
• TMB Substrates Enzyme substrates for ELISA and immunoassay development providing colorimetric detection of target analytes.
• Streptavidin and UltraAvidin™ Streptavidin-based detection reagents with high binding affinity for biotinylated antibodies, optimized for various assay formats. Includes proprietary UltraAvidin™ brand products.
• Custom Antibody Development Services Comprehensive custom antibody services including B-Cell Sequencing, Hybridoma Development, Rabbit Monoclonal Antibody Development, CHO Cell Bioproduction, Recombinant Antibody Production, Polyclonal Antibody Production, and Pilot-Scale Production. Quote-based CDMO service.
• Conjugation Services Custom conjugation services including Antibody Conjugation for IVD, Antibody Oligonucleotide Conjugation, Biotinylation, Fluorescent Reporter Conjugation, NIR-SHIELD™ Conjugation, and Synthetic Nanoparticle Conjugation. Quote-based service.
• Immunoassay Development Services Full-service immunoassay development from planning through cGMP manufacturing, including antibody pairing, assay optimization, performance verification, validation, and scale-up for ELISA and lateral flow platforms. Quote-based CDMO service.
• Protein Production Services Recombinant protein production using mammalian cell expression systems (HEK293 and CHO) with transient or stable expression capabilities. Quote-based CDMO service.
• Protein & Antibody Purification Services Purification services including custom affinity chromatography, Protein A & G affinity chromatography, aseptic/low endotoxin purification, IgM purification, and ion-exchange chromatography with comprehensive bio-analytical testing. Quote-based service.
• Cell Banking Services Master Cell Bank (MCB) and Working Cell Bank (WCB) preparation with mycoplasma testing, sterility testing, biosafety testing, and cell line authentication for consistent manufacturing. Quote-based service.
• Transient Antibody Expression Mammalian transient protein expression using proprietary HEK293 and CHO expression systems for rapid production of highly biologically active antibodies and proteins. Quote-based service.
• Gene Synthesis Custom gene synthesis services for generating DNA sequences for recombinant protein and antibody production. Quote-based service.
• Lateral Flow Assay Development Rapid point-of-care lateral flow assay development from planning through validation phase, providing high-quality components and assay development services for IVD diagnostic and research needs. Quote-based service.

Quantifiable outcome

• Products used to generate data published in high-impact, peer-reviewed scientific journals
• +1 more outcomes

Segments3 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

AI capability1 record

Feature5 records

Partnerships

One partnership is on record.

• CellCartacoreStrategic or Co-development Partner · 23 April 2026Leinco Technologies and CellCarta announced a strategic collaboration to advance proteomics solutions for drug development in immuno-oncology and targeted therapeutic modalities. The partnership integrates Leinco's validated antibody portfolio for immunohistochemistry and spatial biology platforms with CellCarta's Immuno-MRM assays and CPTAC antibody library. This combined offering aims to enhance sensitivity and specificity of proteomic analyses to accelerate biomarker discovery and support personalized medicine approaches.

Scale indicators3 records

Recent moves5 records

Expansion highlights5 records

Broad incumbents

• Abcam (Danaher): Global leader in research antibodies and life science reagents, acquired by Danaher in 2023. Directly comparable as a catalog antibody supplier but with substantially greater catalog breadth, geographic reach, and scale than Leinco.
• Bio-Techne: Large publicly traded life sciences tools company with the R&D Systems, Novus Biologicals, Tocris, and ProteinSimple brands. Directly comparable as a manufacturer of research antibodies, recombinant proteins, cytokines, and ELISA kits serving the same academic and biopharma customer base.
• Thermo Fisher Scientific (Life Sciences Solutions): Diversified life sciences tools giant offering antibodies, reagents, and CDMO services through Invitrogen, Gibco, and Thermo Scientific brands. Competes broadly with Leinco across antibodies, recombinant proteins, and custom services with vastly greater scale.

Direct peers

• GenScript: Global biotechnology company offering gene synthesis, peptide/protein production, antibody development, and CDMO services. Directly comparable to Leinco's custom antibody and protein production service offering with overlapping technology platforms.
• Sino Biological: China-based reagent manufacturer specializing in recombinant proteins, antibodies, and CDMO services. Directly comparable as an antibody/protein manufacturer competing globally on price-performance with overlapping IVD and research customer segments.
• Jackson ImmunoResearch: Specialty manufacturer of secondary antibodies, affinity-purified immunoglobulins, and conjugation reagents. Directly comparable to Leinco's secondary antibody and UltraAvidin™ product lines serving research and IVD markets.
• Santa Cruz Biotechnology: Long-established catalog antibody and reagent supplier serving academic researchers. Directly comparable as a specialty antibody provider competing for similar research customers, though with a different distribution model and brand positioning.
• OriGene Technologies: Specialty antibody and recombinant protein manufacturer offering catalog products and custom services including HEK293/CHO expression. Directly comparable to Leinco's technology platforms and customer base in research antibodies and CDMO services.
• Cell Signaling Technology (CST): Specialty manufacturer of high-quality primary antibodies with deep coverage in cell signaling, cancer biology, and immunology. Closely comparable to Leinco in catalog antibody focus, validation standards, and academic/biopharma customer orientation.
• Rockland Immunochemicals: Privately held manufacturer of antibodies, assay reagents, and custom services for life science and IVD applications. Closely comparable to Leinco in scale, business model, and customer mix including IVD raw materials and custom antibody services.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat4 records

Key risks5 records

Key highlights6 records

Customer concentration

• Xx.com/LeincoSTL
• Facebookfacebook.com/Leinco

Compliance2 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Subsidiaries1 record

Funding overview

Funding rounds1 record

Investors1 record

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A2 records

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Leinco Technologies