UT Southwestern Medical Center

What UT Southwestern Medical Center does

UT Southwestern Medical Center is a public academic medical center headquartered in Dallas, Texas, and part of the University of Texas System. Founded in 1943, it operates William P. Clements Jr. University Hospital as its primary inpatient facility alongside more than 40 outpatient and specialty clinic locations across the Dallas-Fort Worth metroplex and broader North Texas. The institution has been ranked the #1 hospital in DFW by U.S. News & World Report for nine consecutive years and holds 12 nationally ranked specialties — the most in Texas — including cardiology, neurology/neurosurgery, cancer, and transplant services. It is the only NCI-designated Comprehensive Cancer Center in North Texas (Simmons Comprehensive Cancer Center, with 277 faculty across 37 departments) and performs high-acuity procedures such as 458 organ transplants in 2025 (121 liver, 212 kidney, 69 lung, 56 heart). Customer segments span general North Texas residents, cardiovascular and transplant patients, oncology patients, and professional/collegiate sports organizations via institutional healthcare partnerships.

The institution's technology base spans clinical care, translational research, and education, with in-house capabilities including ex vivo lung perfusion (one of fewer than two dozen U.S. centers), osseointegration for amputees (one of two Texas hospitals), SORT nanoparticles for organ-specific CRISPR delivery (licensed to ReCode Therapeutics), the ReMiTT spatial-transcriptomics tool, and a multimodal AI grading system (Jamieson Lab) that replaces over 91% of human OSCE grading. Revenue derives from clinical services billed to commercial insurers, Medicare/Medicaid, and self-pay; federal and state research grants (NIH, NCI, CPRIT, ARPA-H, Cancer Grand Challenges); philanthropy (multi-hundred-million-dollar gifts from Stephens Greth, Moody, Pogue, and Rees-Jones Foundations); industry-sponsored and investigator-initiated clinical trials; and exclusive licensing agreements with biotech firms such as InterAct Therapeutics and ReCode Therapeutics. Recent strategic capital projects include a $5 billion joint pediatric campus with Children's Health (4.9 million sq ft, 552 beds, completion 2031) and the newly opened 292-bed Texas Behavioral Health Center, both funded through a mix of state appropriations and philanthropy. The institution's AI infrastructure was recently upgraded via one of the first IBM Fusion implementations of the NVIDIA AI Data Platform, supporting research and clinical AI workloads at scale.

Name

UT Southwestern Medical Center

Legal name

The University of Texas Southwestern Medical Center

Website

https://utswmed.org

Company type

Public

Founded year

1943

Operating status

Operating

Headcount range

5,001–10,000 employees

Short description

UT Southwestern Medical Center is a public academic medical center in Dallas, Texas, operating William P. Clements Jr. University Hospital and 40+ outpatient locations across North Texas. It serves as the #1-ranked DFW hospital for nine consecutive years with 12 nationally ranked specialties and the only NCI-designated Comprehensive Cancer Center in North Texas.

Ownership category

akta.pro rank

Product category

Academic Medical Center

NAICS

General Medical and Surgical Hospitals (62211), General Medical and Surgical Hospitals (6221), Diagnostic Imaging Centers (621512)

SIC

Services-General Medical & Surgical Hospitals, Nec (8062), Services-Hospitals (8060)

akta.pro primary industry

Community & Regional General Hospitals (HLAFAAAB)

akta.pro secondary industries

Advanced Imaging & Specialty Radiology Centers (PET/CT, Nuclear Medicine, Interventional Radiology) (HLAFAKAB), Hospital-Integrated Cancer Centers (Acute Oncology Programs) (HLAFAAAM)

Keywords

• Academic medical center
• Clinical healthcare services
• Organ transplant services
• Oncology treatment programs
• Medical research services

Headquarters

HQ city

Dallas

HQ country

United States

HQ region

North America

Offices14 records

Markets served

GTM type

B2B and B2C

Offering type

Services

Cost components

Personnel, Operations, Technology or R&D, Infrastructure, Marketing or Sales, Supply Chain

Revenue model

1. Clinical Healthcare Services: Revenue generated from patient care services across hospital, outpatient, and specialty clinics, including transplant, cardiac, cancer, neuroscience, and surgical services. Billed through insurance, Medicare, Medicaid, and self-pay. UT Southwestern accepts a broad range of insurance plans including Aetna, Blue Cross Blue Shield, Cigna, Humana, United Healthcare, and various Texas Medicaid managed care plans.
2. Federal and State Research Grants: Funding from agencies including NIH, NCI, CPRIT, and ARPA-H supporting basic, translational, and clinical research. CPRIT has invested over $250 million in grants to UT Southwestern since 2009. ARPA-H awards have provided up to $25 million for specific projects such as the VITAL bioengineered liver program.
3. Philanthropy and Foundation Donations: Major gifts and donations from foundations and individuals supporting capital projects and research programs. The Stephens Greth Foundation contributed $100 million toward the $5 billion pediatric campus. Moody Foundation, Pogue Foundation, and Rees-Jones Foundation have each contributed nine-figure donations.
4. Clinical Trials: Revenue from industry-sponsored and investigator-initiated clinical trials conducted across cancer, cardiovascular, neuroscience, and other specialty areas. Hundreds of active clinical trials are ongoing.
5. Licensing and Commercialization Agreements: Exclusive licensing agreements with biotech companies such as InterAct Therapeutics for gene therapy platforms and computational tools developed at UT Southwestern. Daniel Siegwart's SORT nanoparticle technology was licensed to ReCode Therapeutics.

Pricing tiers

Go-to-market motion1 record

Distribution channels5 records

Marketing channels8 records

Core offering

UT Southwestern Medical Center delivers comprehensive clinical care across all major specialties (transplant, cardiology, oncology, neuroscience, spine, vascular, thoracic, allergy/immunology, and behavioral health) through its university hospital and 40+ outpatient locations. The center combines patient care with biomedical research, medical education, and clinical trials, generating revenue through insurance reimbursement, federal/state grants (NIH, CPRIT, ARPA-H), philanthropy, and licensing of internally developed therapies and technologies.

Product overview

UT Southwestern Medical Center is an academic medical center offering a broad portfolio of clinical care programs, digital patient engagement tools, and specialized medical and surgical services. Its primary patient-facing digital product is the UTSWMyCare mobile app, which integrates MyChart for electronic health record access and connects with Uber and Lyft for appointment transportation. The medical center operates major clinical programs including a comprehensive Transplant Program (heart, lung, kidney, liver, pancreas, and living-donor transplantation), a Spine Center (offering minimally invasive, endoscopic, and robotic spine surgery), LVAD Surgery for advanced heart failure, Ex Vivo Lung Perfusion for donor lung repair, Thoracic Surgery, Vascular Surgery, and an Allergy, Immunology, and Pulmonary Clinic. Key institutes include the O'Donnell Brain Institute and the NCI-designated Simmons Comprehensive Cancer Center. Flagship facilities include William P. Clements Jr. University Hospital, with over 40 locations across the Dallas-Fort Worth area.

Differentiator

Problem solved

Functional benefit

Brands

• Simmons Comprehensive Cancer Center: NCI-designated Comprehensive Cancer Center providing comprehensive cancer care and research
• O'Donnell Brain Institute
• Clements University Hospital
• Texas Behavioral Health Center
• UTSWMyCare

Products and services

• Transplant Program Comprehensive solid organ transplant program offering heart, lung, kidney, liver, and pancreas transplants, including living-donor kidney and liver transplantation. Performed 458 organ transplants in 2025 and over 2,000 kidney transplants since 1964.
• LVAD Surgery Program Left Ventricular Assist Device (LVAD) implantation program for patients with advanced heart failure, serving as bridge-to-transplant or destination therapy. UT Southwestern is one of an exclusive group of U.S. hospitals approved for LVAD destination therapy and is Joint Commission-certified for ventricular assist devices.
• Ex Vivo Lung Perfusion (EVLP) Technology that assesses, repairs, and restores donor lungs outside the body for transplantation, enabling evaluation beyond the standard six-hour window and expanding the pool of usable donor lungs. UT Southwestern is one of fewer than two dozen U.S. centers using EVLP and performs over 60 lung transplantations annually.
• Spine Center Multidisciplinary spine care program offering minimally invasive spinal surgery, interventional spine care, endoscopic spinal surgery, spine surgery, scoliosis and spinal deformity treatment, and complex revision spinal surgery using advanced technologies including robotic-assisted procedures. Rated High Performing for back surgery (spinal fusion) by U.S. News & World Report.
• Thoracic Surgery Program General thoracic surgery program providing comprehensive care for diseases of the chest and upper gastrointestinal system, including esophageal cancer, lung cancer, mediastinal tumors, and tracheal conditions, using minimally invasive procedures such as VATS and robotic-assisted technology.
• Vascular Surgery Program Vascular surgery program offering advanced interventional therapies and surgical procedures for all forms of vascular disease, including abdominal aortic aneurysm, carotid artery disease, deep vein thrombosis, peripheral vascular disease, and varicose veins, backed by an accredited noninvasive vascular ultrasound laboratory (IAC accredited since 1993).
• Allergy, Immunology, and Pulmonary Clinic Specialized clinic providing care for lung disorders, allergic disorders, asthma, and immunodeficiency disorders, featuring general pulmonology, an Interstitial Lung Disease and Pulmonary Fibrosis Program designated as a Pulmonary Fibrosis Foundation Care Center Site (the first in North Texas, one of 50 nationwide), and an Allergy and Immunology program offering the latest biologic therapies.
• Simmons Comprehensive Cancer Center NCI-designated Comprehensive Cancer Center (one of 57 in the U.S. and the only one in North Texas) with 277 faculty members across 37 departments, hundreds of active clinical trials, and research programs in immunotherapy, gene therapy, and computational oncology.
• O'Donnell Brain Institute Integrated brain institute at UT Southwestern conducting research and clinical care across neuroscience disciplines, including participation in the TRANSCEND clinical trial for deep brain stimulation in treatment-resistant depression.
• Video Visits (Virtual Care) Telemedicine service integrated into the UTSWMyCare app allowing patients to have video consultations with UT Southwestern providers from any location, covering a broad spectrum of primary and specialty services with the same quality of care as in-person visits.
• UTSWMyCare App Patient care mobile application that enables patients to find physicians, access medical records, get lab results, request prescription refills, message providers, schedule appointments, conduct video visits, navigate campus with turn-by-turn directions, and access shuttle and ride-sharing services. Connects to MyChart.
• Clinical Trials Program Hundreds of active clinical trials across cancer, cardiovascular, neuroscience, and other specialty areas, including industry-sponsored and investigator-initiated trials. Patients gain access to experimental therapies and research-based treatments not available elsewhere.
• Texas Behavioral Health Center New 292-bed psychiatric hospital in Dallas operated by UT Southwestern, funded by the state of Texas as part of a $2.5 billion statewide mental health infrastructure investment. Provides inpatient psychiatric care including a pediatric wing operated in conjunction with Children's Health.
• Osseointegration Surgery (Bone-Anchored Prosthesis) Innovative osseointegration procedure allowing amputees to have prosthetic limbs directly attached to titanium implants inserted into bone, providing more natural mobility. UT Southwestern is one of only two hospitals in Texas offering this procedure.

Quantifiable outcome

• 458 total organ transplants performed in 2025, including 121 liver transplants (7th consecutive year as highest volume in North Texas), 212 kidney transplants, 69 lung transplants, and 56 heart transplants
• +6 more outcomes

Named customers10 records

Segments6 records

Ideal customer profiles7 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration3 records

AI capability12 records

Feature6 records

Partnerships

15 partnerships are on record, tiered minor and core.

• IdefineminorStrategic or Co-development Partner · 4 June 2026Idefine and The Kleefstra Syndrome Foundation announced a collaboration with UT Southwestern to advance gene therapy development for Kleefstra syndrome, a rare neurodevelopmental disorder caused by changes or loss of the EHMT1 gene.
• Dallas PulseminorStrategic or Co-development Partner · 6 May 2026UT Southwestern is partnering with Dallas Pulse for sports medicine support, providing healthcare services to the professional sports organization.
• InterAct TherapeuticscoreStrategic or Co-development Partner · 24 March 2026Exclusive licensing agreement to develop and commercialize a computational platform and gene therapy pipeline targeting cancer metastasis. Lead asset IAT-S2 is a first-in-class AAV8-based gene therapy for breast cancer liver metastasis. InterAct was selected for the Charles River Incubator Program and is advancing toward clinical trials following FDA discussions.
• Pennsylvania State UniversitycoreStrategic or Co-development Partner · 13 January 2026Collaborating with UT Southwestern on the ARPA-H VITAL project, a five-year initiative to bioengineer fully functional, patient-specific artificial livers using 3D bioprinting techniques. Human testing potentially beginning in approximately five years.
• University of California, DaviscoreStrategic or Co-development Partner · 13 January 2026Collaborating with UT Southwestern on the ARPA-H VITAL project for bioengineering artificial livers using patient-specific cells and 3D bioprinting techniques.
• IBM (NVIDIA AI Data Platform)coreTechnology or Integration · 4 November 2025IBM Fusion implemented NVIDIA AI Data Platform for UT Southwestern, marking one of the industry's first deployments of this reference design, enhancing large-scale AI training, inference, and complex data processing for research and clinical applications.
• March of DimesminorStrategic or Co-development Partner · 29 October 2025UT Southwestern partnered with UTMB and March of Dimes on the Texas Collaborative Prematurity Research Center in Arlington, Texas, utilizing large patient cohorts and AI and pregnancy-on-a-chip technologies to study and develop treatments for preterm birth.
• Signify BiominorStrategic or Co-development Partner · 5 June 2025Dallas-based biotech company co-founded by UT Southwestern's Daniel J. Siegwart, focused on harnessing the human body for in situ protein therapeutics. Launched with $15 million oversubscribed financing round.
• Pfizer Inc.coreStrategic or Co-development Partner · 1 February 2024Collaboration between UT Southwestern Medical Center and Pfizer to advance RNA-enhanced delivery methods for genetic medicine therapies, as noted in a market assessment report on the RNA-targeted small molecules sector.
• ReCode TherapeuticscoreOEM/ Whitelabel/ Licensing PartnerDaniel Siegwart's SORT nanoparticle technology for organ-specific CRISPR delivery, developed at UT Southwestern, was licensed to ReCode Therapeutics for clinical development.
• Penn StateminorStrategic or Co-development PartnerPenn State is a sub-awardee on ARPA-H research teams under the PRINT program, with field testing planned at UT Southwestern facilities alongside other medical centers, schools, and daycare facilities.
• UT DallascoreStrategic or Co-development PartnerCollaborating institution for the North Texas Alzheimer's Disease Research Center, funded by the National Institute on Aging (NIH) with $23 million over five years. UT Dallas contributes AI and machine learning capabilities including voice analysis and digital twin technology.
• UT ArlingtoncoreStrategic or Co-development PartnerCollaborating institution for the North Texas Alzheimer's Disease Research Center, funded by the National Institute on Aging with $23 million over five years.
• University of SheffieldminorStrategic or Co-development PartnerCollaborated with UT Southwestern scientists on research identifying HSF1 stress-response protein that could protect healthy cells from chemotherapy side effects. Study published in Molecular Cell.
• GE HealthCarecoreTechnology or IntegrationUT Southwestern is an early evaluator site for GE HealthCare's CareIntellect Oncology platform, a cloud-based generative AI application integrating radiology, pathology, and genomics data for cancer care. Early pilots reported 80% reduction in information hunting time and chart review time dropping from 45 to 9 minutes.

Scale indicators14 records

Recent moves6 records

Expansion highlights7 records

Direct peers

• Baylor Scott & White Health: Largest not-for-profit health system in North Texas; UT Southwestern's primary competitor for complex and specialty referrals in the Dallas-Fort Worth market, with overlapping transplant, oncology, and cardiovascular programs.
• Parkland Health: Dallas County's public safety-net hospital and major trauma center; directly competes with UT Southwestern for emergency, complex, and uninsured populations in the same Dallas Medical District footprint.
• Texas Children's Hospital: Houston-based pediatric academic medical center with which UT Southwestern/Children's Health joint pediatric campus will directly compete for high-acuity pediatric cases statewide and across the Southwestern U.S.
• Children's Health (Dallas): Joint venture partner on the $5B, 552-bed pediatric campus; UT Southwestern provides the academic medical/clinical backbone for the new pediatric hospital, making them operationally and financially linked rather than purely competitive.
• Dell Seton Medical Center (UT Health Austin): Sister UT System academic medical campus; shares UT System governance, medical school training pipelines, and translational research orientation, providing a comparable academic operating model in a different Texas metro.
• UT MD Anderson Cancer Center: Fellow UT System NCI-designated Comprehensive Cancer Center focused exclusively on oncology; comparable in research intensity and translational pipeline, and the natural destination for the highest-acuity oncology cases that Simmons Cancer Center escalates.

Broad incumbents

• Houston Methodist: Texas-based, research-integrated academic hospital system with nationally ranked specialties; comparable size, research funding footprint, and complex-care orientation, providing a benchmark for UT Southwestern's national ambition.
• Texas Health Resources: Large regional health system headquartered in Arlington, Texas; several UT Southwestern specialty clinics are physically located on Texas Health Dallas (Texas Health Presbyterian) campuses, creating both partnership overlap and competitive proximity for general and specialty volumes.
• Mayo Clinic: National reference academic medical center with integrated research-clinical model and deep philanthropic engine; UT Southwestern benchmarks against Mayo Clinic for translational research productivity and national specialty rankings.

Regional players

• Medical City Healthcare (HCA): Operates Medical City Dallas and a large DFW-area hospital network; competes for elective specialty surgical volumes and ambulatory cases in the same North Texas geography.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat7 records

Key risks5 records

Key highlights7 records

Customer concentration

• Xx.com/utswnews
• YouTubeyoutube.com/user/UTSWMed
• Facebookfacebook.com/utswmed
• LinkedInlinkedin.com/company/simmons-comprehensive-cancer-center

Compliance4 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles8 records

Subsidiaries3 records

Funding overview

Funding rounds3 records

Investors4 records

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M&A

Investments

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Frequently asked questions about UT Southwestern Medical Center