y prime
YPrime provides a unified eClinical technology platform—eCOA, IRT, eConsent, and patient engagement—for global clinical trials. It serves pharmaceutical sponsors, CROs, and emerging biotechs across 19+ therapeutic areas and 100+ countries via enterprise SaaS subscriptions.
- Company typePrivate
- Founded2009
- HeadquartersMalvern, United States
- Headcount51–100
- GTM typeB2B
- OfferingSoftware
What y prime does
YPrime (legally Y-Prime, LLC) is a Malvern, Pennsylvania-based provider of eClinical technology solutions for clinical trials, operating in the space for 16+ years since its founding in 2009. The company offers a unified Clinical Trial Technology Platform comprising four core products: eCOA (electronic Clinical Outcome Assessment), IRT (Interactive Response Technology), eConsent, and Patient Engagement, supplemented by Consulting Services. The platform is built on configurable, no-code architecture with pre-validated code and integrated data flows across the three core modules, and is delivered globally across 100+ countries with a 24/7/365 in-house help desk staffed by eClinical experts.
The company serves three primary customer segments: large pharmaceutical sponsors, contract research organizations (CROs), and emerging biotechnology companies, targeting complex global clinical trials across 19+ therapeutic areas including oncology, rare disease, CNS, cardiometabolic, vaccines, and ophthalmology. YPrime has implemented approximately 1,000 clinical studies and its solutions have engaged 125,000+ patients. The firm claims that its enterprise-grade eCOA accelerates study startup timelines by approximately 50% and that its IRT platform supports complex trial designs and rapid protocol amendments without operational bottlenecks. The platform is sold via direct enterprise sales with RFP and Demo CTAs as primary engagement mechanisms, with no evidence of channel or reseller distribution in the available data.
YPrime operates on a subscription-based enterprise SaaS revenue model with quote-based pricing for its technology platform, complemented by professional services revenue from consulting engagements on process optimization, system integration, and inspection readiness. The firm is privately held and PE-backed, having received equity and debt capital from Ballast Point Ventures ($5M, 2013), Square 1 Bank ($5M, 2016), and Flexpoint Ford (2019), and acquired patient engagement specialist Tryl in February 2022 to bolster its participant engagement capabilities. Revenue, valuation, ownership percentages, and the identity of the PE sponsor are not publicly disclosed.
y prime firmographics
Firmographics- Name
- y prime
- Legal name
- Y-Prime, LLC
- Website
- https://y-prime.com
- Company type
- Private
- Founded year
- 2009
- Operating status
- Operating
- Headcount range
- 51–100 employees
- Short description
- YPrime provides a unified eClinical technology platform—eCOA, IRT, eConsent, and patient engagement—for global clinical trials. It serves pharmaceutical sponsors, CROs, and emerging biotechs across 19+ therapeutic areas and 100+ countries via enterprise SaaS subscriptions.
- Ownership category
- akta.pro rank
y prime industry classification
Industry- Product category
- Clinical Trial Technology (eClinical)
- NAICS
- Custom Computer Programming Services (541511), Other Computer Related Services (541519)
- SIC
- Services-Commercial Physical & Biological Research (8731), Services-Computer Programming Services (7371)
- akta.pro primary industry
- Randomization & Trial Supply Management (RTSM/IRT/IVRS/IWRS) (HLACAOAC)
- akta.pro secondary industry
- Decentralized/Hybrid Trial Enablement (DCT) Platforms (HLACAOAL)
Keywords
Where y prime is headquartered
LocationHeadquarters
- HQ city
- Malvern
- HQ country
- United States
- HQ region
- North America
Markets served
y prime business model
Business model- GTM type
- B2B
- Offering type
- Software
- Cost components
- Personnel, Technology or R&D, Operations, Marketing or Sales, Infrastructure
Revenue model
- eClinical Technology Platform: Subscription-based access to eCOA, IRT, and eConsent platforms for clinical trials with configurable architecture and global delivery
- Consulting Services: Expert guidance services extending the clinical trial technology platform including process optimization, regulatory alignment, system integration, and data workflow optimization
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| Subscription | Annual | Enterprise platform pricing |
Go-to-market motion1 record
Distribution channels1 record
Marketing channels6 records
y prime product offering
Product offeringCore offering
YPrime provides eClinical technology solutions for clinical trials, including electronic Clinical Outcome Assessment (eCOA), Interactive Response Technology (IRT), electronic Consent (eConsent), and patient engagement tools, supporting pharmaceutical sponsors and CROs in accelerating study startup, managing protocol amendments, and ensuring data quality across global clinical trials.
Product overview
YPrime offers a unified Clinical Trial Technology Platform comprising four core integrated solutions—eCOA (electronic Clinical Outcome Assessment), IRT (Interactive Response Technology), eConsent, and Patient Engagement—supplemented by Consulting Services. The platform is designed for global scale and complex clinical trial protocols across oncology, rare disease, CNS, cardiometabolic, vaccines, and ophthalmology therapeutic areas. Built with configurable architecture and integrated data flows, it enables sponsors and CROs to accelerate study startup, adapt to protocol changes, and maintain data integrity and regulatory oversight throughout trial execution.
Differentiator
Problem solved
Functional benefit
Products and services
- eCOA (Electronic Clinical Outcome Assessment) Electronic clinical outcome assessment solution for capturing patient-reported outcomes and clinical endpoint data in regulated clinical trials, intended for pharmaceutical sponsors and CROs.
- IRT (Interactive Response Technology) Interactive response technology system for randomization, patient and drug assignment, and trial supply management in clinical trials, intended for pharmaceutical sponsors and CROs.
- eConsent Electronic informed consent solution for capturing and managing participant consent in clinical trials, intended for pharmaceutical sponsors and CROs.
- Participant Engagement Patient engagement platform for clinical trial participants, supporting participant interaction, reminders, and engagement workflows across global trials, intended for pharmaceutical sponsors and CROs.
Quantifiable outcome
- ~50% acceleration in clinical trial startup timelines
- +2 more outcomes
Companies that use y prime
Customer profileNamed customers3 records
Segments3 records
Ideal customer profiles1 record
y prime technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Feature5 records
y prime partnerships and signals
Strategic signalPartnerships
One partnership is on record.
- TrylminorYPrime acquired Tryl, a company specializing in patient engagement solutions. The acquisition enhances YPrime's patient engagement capabilities within its clinical trial technology platform. PE-backed YPrime completed the acquisition, though specific transaction details were not disclosed.
Scale indicators6 records
Recent moves6 records
Expansion highlights6 records
y prime competitors and assessment
Company assessmentDirect peers
- Clario: Clario (formed from the merger of Bioclinica and ERT) provides eCOA, IRT, cardiac safety, and imaging solutions for clinical trials. Its eCOA franchise competes head-to-head with YPrime's configurable eCOA platform for global, regulated studies.
- Signant Health: Signant Health (formerly CRF Health and Bracket) specializes in eCOA, eConsent, patient engagement, and clinical rater training. Its focus on patient-centric trial technology directly mirrors YPrime's eCOA + eConsent + patient engagement offering.
- Veeva Systems: Veeva's Vault CDB and Vault EDC extend into eCOA, IRT, and eConsent functionality, sold primarily to large pharma sponsors. Its deep CRM and content-management penetration into the same top-15 pharma accounts makes it a directly comparable competitor in enterprise eClinical RFPs.
- Medidata Solutions (Dassault Systèmes): Medidata is the market-leading eClinical platform, offering Rave EDC, eCOA, RTSM/IRT, and eConsent across global clinical trials. It is the most direct large-scale competitor to YPrime's integrated eCOA/IRT/eConsent stack, with substantially greater scale and a broader sponsor footprint.
Emerging players
- Castor: Castor offers a configurable, cloud-based EDC and eCOA platform aimed at academic and emerging biotech sponsors. It competes with YPrime in the lower-end and mid-market where configurability and speed-to-startup are key buying criteria.
- ArisGlobal: ArisGlobal's LifeSphere Clinical platform includes EDC, RTSM, safety, and trial management modules competing for the same mid-tier sponsor RFPs as YPrime. Its broader suite approach mirrors how YPrime competes against larger bundled platforms.
- Advarra: Advarra combines clinical technology (including eRegulatory and eConsent) with IRB and biosafety services for research sites and sponsors. Its eConsent capability partially overlaps with YPrime's offering and is often co-sold with broader technology stacks.
- Medrio: Medrio provides cloud-based EDC, eCOA, and eConsent for clinical trials, with a strong footprint among emerging biotechs and CROs. Its eCOA and eConsent overlap with YPrime's core products for smaller and mid-sized sponsors.
Broad incumbents
- IQVIA: IQVIA combines CRO services with the Orchestrated Clinical Trials platform (ECT) that includes EDC, RTSM, and eCOA. Its full-service CRO-plus-technology model competes with YPrime for sponsor budgets where services and technology are procured jointly.
- Oracle Health Sciences (Clinical One): Oracle's Clinical One platform unifies EDC, RTSM, eCOA, and supply management within Oracle's broader life sciences cloud. As a broad incumbent with deep enterprise IT relationships, Oracle competes in the same eClinical RFPs from a much larger platform footprint.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat5 records
Key risks6 records
Key highlights7 records
Customer concentration
y prime social profiles
Digital presencey prime financial estimates
Financial estimateRevenue estimate
Valuation estimate
y prime leadership team
Management profileNumber of profiles
y prime subsidiaries and ownership
Company hierarchySubsidiaries1 record
y prime funding detail
Funding detailFunding overview
Funding rounds4 records
Investors3 records
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
y prime M&A and investment
M&A and investmentM&A1 record
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about y prime
What does y prime do?
YPrime provides eClinical technology solutions for clinical trials, including electronic Clinical Outcome Assessment (eCOA), Interactive Response Technology (IRT), electronic Consent (eConsent), and patient engagement tools, supporting pharmaceutical sponsors and CROs in accelerating study startup, managing protocol amendments, and ensuring data quality across global clinical trials.
Is y prime a public or private company?
y prime is a private company. It is classified as private equity controlled and is currently operating.
When was y prime founded?
y prime was founded in 2009. It employs 51 to 100 people.
Where is y prime based?
y prime is headquartered in Malvern, United States, in the North America region.
How does y prime make money?
Two revenue lines are on record. eClinical Technology Platform is the primary driver. The others are consulting Services.
Who are y prime's main competitors?
Direct peers on record are Clario, Signant Health, Veeva Systems and Medidata Solutions (Dassault Systèmes). Emerging players are Castor, ArisGlobal, Advarra and Medrio. Broad incumbents are IQVIA and Oracle Health Sciences (Clinical One).
Does y prime have an API?
No public API is recorded for y prime.
What industry is y prime in?
y prime's product category is Clinical Trial Technology (eClinical). Its primary akta.pro industry code is HLACAOAC, Randomization & Trial Supply Management (RTSM/IRT/IVRS/IWRS), with a secondary code of HLACAOAL, Decentralized/Hybrid Trial Enablement (DCT) Platforms. Its NAICS code is 541511 and its SIC code is 8731.