Advarra
Advarra is a Columbia, Maryland-based clinical research technology company providing central IRB review, enterprise CTMS (OnCore, Clinical Conductor), and the Study Collaboration site platform for pharma sponsors, CROs, and 3,500+ academic and research institutions worldwide.
- Company typePrivate
- Founded1993
- HeadquartersColumbia, United States
- Headcount501–1,000
- GTM typeB2B
- OfferingSoftware
What Advarra does
Advarra is a Columbia, Maryland-based clinical research technology company serving sponsors, CROs, academic medical centers, and investigator sites across the drug development lifecycle. Founded in 1993 and operating with 501-1,000 employees, it provides AAHRPP-accredited central IRB review services (CIRBI), enterprise CTMS platforms (OnCore for academic medical centers, Clinical Conductor for sites), an investigator community covering 50,000+ investigators, complementary offerings in IBC review, eSource, eRegulatory, DMC oversight, and GxP services, plus the Study Collaboration protocol site-portal product (formerly Longboat). The company reports 3,500+ institutions on its networks, 12,000+ open protocols annually, 3M+ patient visits, and $4B+ in trial invoice value flowing through its systems, with claimed penetration of 88% of NCI-designated cancer centers and 100% of top-10 pharma sponsors and CROs for IRB services.
Revenue mechanics combine multi-year subscription licenses for CTMS and Study Collaboration, per-protocol IRB and IBC review fees, ancillary compliance services, and enterprise contracts with major sponsors and CROs. Recent commercial activity in 2025-2026 — including the launch of the Braid AI and analytics platform and an AI-powered Study Design product, the appointment of a CTO, the addition of five eClinical partner integrations, an EHR-to-EDC interoperability partnership with IgniteData, and a site-network partnership with ICON plc — points to an explicit strategy to extend Advarra from review and workflow systems into an AI-enabled data and protocol design layer for the broader clinical research stack.
Advarra firmographics
Firmographics- Name
- Advarra
- Legal name
- Advarra, Inc.
- Website
- https://advarra.com
- Company type
- Private
- Founded year
- 1993
- Operating status
- Operating
- Headcount range
- 501–1,000 employees
- Short description
- Advarra is a Columbia, Maryland-based clinical research technology company providing central IRB review, enterprise CTMS (OnCore, Clinical Conductor), and the Study Collaboration site platform for pharma sponsors, CROs, and 3,500+ academic and research institutions worldwide.
- Ownership category
- akta.pro rank
Advarra industry classification
Industry- Product category
- Clinical Trial Management Software
- NAICS
- Custom Computer Programming Services (541511)
- SIC
- Services-Prepackaged Software (7372), Services-Computer Programming Services (7371)
- akta.pro primary industry
- Clinical CROs (Phase I–IV) (HLAGAAAA)
- akta.pro secondary industries
- Patient Recruitment, Site Feasibility & Trial Enablement CROs (HLAGAAAI), Electronic Data Capture (EDC) Platforms (HLACAOAA)
Keywords
Where Advarra is headquartered
LocationHeadquarters
- HQ city
- Columbia
- HQ country
- United States
- HQ region
- North America
Offices1 record
Markets served
Advarra business model
Business model- GTM type
- B2B
- Offering type
- Software
- Cost components
- Personnel, Technology or R&D, Operations, Marketing or Sales, Infrastructure
Revenue model
- CTMS Platform Subscriptions: Annual or multi-year subscription licensing for OnCore and Clinical Conductor CTMS platforms, typically sold as enterprise agreements to research sites, academic medical centers, and health systems.
- Study Collaboration Platform: Subscription-based access to connected site network and eClinical integrations for sponsors and CROs, with per-seat or site-based licensing models.
- IRB Review Services: Regulatory review services for clinical trials, providing independent oversight with speed and transparency. Revenue from review fees and service agreements.
- AI and Data Platform (Braid): AI-powered insights and operational intelligence services, likely bundled with platform subscriptions or offered as add-on capabilities.
- Professional Services: Consulting and professional services including study startup, coverage analysis, budget negotiation, and CTMS configuration services.
Go-to-market motion2 records
Distribution channels4 records
Marketing channels9 records
Advarra product offering
Product offeringCore offering
Advarra provides clinical research technology and regulatory oversight products, including IRB review services through its CIRBI platform, enterprise CTMS solutions (OnCore and Clinical Conductor), eSource and eRegulatory document systems for research sites, and a Study Collaboration platform that connects sponsors, CROs, and sites via single sign-on to integrated eClinical technologies. Its Braid AI and data engine adds operational intelligence across the protocol lifecycle.
Product overview
Advarra is a clinical research technology platform combining IRB oversight, operational intelligence, and collaborative trial management. The core offerings include CIRBI for IRB services and the Braid AI and data engine platform. For research sites, Advarra provides OnCore (enterprise CTMS for academic medical centers and cancer centers) and Clinical Conductor (CTMS for sites, networks, and health systems), along with eReg (regulatory document management) and eSource (electronic data capture). For sponsors and CROs, the Study Collaboration platform integrates AI-powered Study Design, Site Identification & Feasibility, Study Startup, Site Collaboration & Training, and Enrollment Planning & Tracking. Additional offerings include IBC, DMC, and GxP compliance services. The Braid platform weaves operational intelligence from Advarra's IRB and clinical trial systems throughout the entire protocol lifecycle.
Differentiator
Problem solved
Functional benefit
Brands
- CIRBI: IRB platform for managing institutional review board submissions and reviews
- OnCore
- Clinical Conductor
- Braid
- Study Collaboration
- eReg
- eSource
- IBC Services
- DMC Services
Products and services
- CIRBI (Center for IRB Intelligence) Advarra's IRB platform providing independent, rigorous oversight with speed, expertise and transparency for ethical review of clinical research protocols, used by 100% of the top 10 pharmaceutical sponsors and CROs.
- Braid Advarra's AI and data engine platform that weaves operational intelligence into the protocol lifecycle, powering Study Collaboration and providing actionable insights for smarter study design, faster decisions, and AI-automated workflows.
- OnCore Enterprise CTMS designed for academic medical centers and cancer centers, managing all operational aspects of clinical trials from study startup to closeout. Used by 88% of NCI-designated cancer centers.
- Clinical Conductor CTMS for research sites, site networks, hospitals, and health systems to manage research operations, study conduct, financial management, billing, and regulatory compliance.
- eReg Electronic regulatory document management and exchange system for efficient regulatory compliance at research sites.
- eSource Integrated data capture and oversight system enabling electronic source documentation for clinical trials.
- Study Collaboration (formerly Longboat) Study collaboration solution providing sponsors, CROs, and research sites a single access point for clinical trial systems with single sign-on, credential management, and integrated eClinical technology partners.
- IBC (Institutional Biosafety Committee) Services Review and audit services for institutional biosafety committee oversight of gene therapy, cell therapy, and biologics research.
- DMC (Data Monitoring Committee) Services Data monitoring committee services providing independent oversight of clinical trial safety data.
- GxP Compliance Intelligence Compliance intelligence services for GxP regulatory requirements in clinical research.
Quantifiable outcome
- 88% of NCI-designated cancer centers use Advarra technology
- +6 more outcomes
Companies that use Advarra
Customer profileNamed customers8 records
Segments3 records
Ideal customer profiles3 records
Advarra technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- Yes
- API docs
- API detail
Core technology
AI maturity
App detail
Integration13 records
AI capability6 records
Feature8 records
Advarra partnerships and signals
Strategic signalPartnerships
Seven partnerships are on record, tiered core and secondary.
- ICON plccoreDefinitive partnership to introduce a 'research-ready' connected site network model for clinical trials globally. Integration of ICON's global clinical trial solutions with Advarra's site CTMSs, eISF, and eSource systems used by 50,000+ investigators. Aims to reduce administrative friction, accelerate study startup, and increase clinical trial participation.
- YPrimesecondaryeClinical technology partner integrated into Advarra's Study Collaboration solution. YPrime provides clinical trial technology solutions and is part of the expanded partner network providing single sign-on access through Advarra's platform.
- ScoutsecondaryeClinical technology partner integrated into Advarra's Study Collaboration solution. Scout's technology is accessible through single sign-on within Advarra's platform ecosystem.
- SuvodasecondaryeClinical technology partner integrated into Advarra's Study Collaboration solution. Suvoda's solutions are accessible through single sign-on within Advarra's platform.
- DatacubedsecondaryeClinical technology partner integrated into Advarra's Study Collaboration solution. Datacubed's technology is accessible through single sign-on within Advarra's platform.
- EndpointsecondaryeClinical technology partner integrated into Advarra's Study Collaboration solution. Endpoint's technology is accessible through single sign-on within Advarra's platform.
- IgniteDatacorePartnership to enhance clinical trial data transfer between research sites' EHR systems, Advarra's eSource and EDC systems, and sponsor EDC systems. Collaboration aims to improve data accuracy, reduce administrative burden, and accelerate clinical trial conduct.
Scale indicators8 records
Recent moves8 records
Expansion highlights5 records
Advarra competitors and assessment
Company assessmentDirect peers
- Veeva Systems: Veeva provides CTMS, eTMF, Vault Clinical, and a broad clinical operations suite for pharma sponsors and CROs, competing directly with Advarra's Study Collaboration and CTMS offerings for sponsor-side wallet share.
- Medidata (Dassault Systèmes): Medidata's Rave EDC, CTMS, eCOA, and RTSM platform competes with Advarra's eSource, Clinical Conductor, and integrated eClinical partners across sponsor and CRO customers.
- WCG (WIRB-Copernicus Group): WCG is Advarra's most direct IRB services competitor, providing independent review boards and clinical services to sponsors, CROs, and research sites across all therapeutic areas.
- Clario (formerly ERT): Clario provides eCOA, cardiac safety, respiratory, and imaging solutions integrated into clinical trials, directly competing with Advarra's eClinical partner ecosystem for sponsor eClinical spend.
- Signant Health: Signant Health offers eCOA, eConsent, RTSM, patient engagement, and clinical supply technology, overlapping with Advarra's Study Collaboration partner integrations and eSource offerings.
Broad incumbents
- Oracle Health Sciences (Clinical One): Oracle's Clinical One platform unifies EDC, RTSM, CTMS, and ePRO, competing with Advarra's integrated eClinical vision for large enterprise pharma customers.
- IQVIA Technologies: IQVIA combines CRO services with proprietary clinical trial technology (e.g., IQVIA Technologies, Digital Trial Solutions), positioning as a broader incumbent that overlaps with Advarra's sponsor-side offerings.
Emerging players
- Florence Healthcare: Florence provides eISF and site-focused clinical trial technology that directly competes with Advarra's eReg, eISF, and site CTMS offerings for academic and community research sites.
- Castor: Castor offers an EDC and eClinical platform with strong adoption among academic medical centers and emerging sponsors, competing with Advarra's Clinical Conductor and eSource offerings in the site segment.
Others
- ICON plc: ICON is both Advarra's strategic partner (connected site network) and a global CRO with proprietary technology. As a distribution partner, ICON extends Advarra's reach; as a CRO with competing site technology, it represents a complex peer relationship.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat6 records
Key risks6 records
Key highlights7 records
Customer concentration
Advarra social profiles
Digital presenceAdvarra compliance and trust
Trust signalCompliance7 records
Advarra financial estimates
Financial estimateRevenue estimate
Valuation estimate
Advarra leadership team
Management profileNumber of profiles
Profiles9 records
Advarra funding detail
Funding detailFunding overview
Funding rounds
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Advarra M&A and investment
M&A and investmentM&A6 records
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Advarra
What does Advarra do?
Advarra provides clinical research technology and regulatory oversight products, including IRB review services through its CIRBI platform, enterprise CTMS solutions (OnCore and Clinical Conductor), eSource and eRegulatory document systems for research sites, and a Study Collaboration platform that connects sponsors, CROs, and sites via single sign-on to integrated eClinical technologies. Its Braid AI and data engine adds operational intelligence across the protocol lifecycle.
Is Advarra a public or private company?
Advarra is a private company. It is classified as unknown and is currently operating.
When was Advarra founded?
Advarra was founded in 1993. It employs 501 to 1,000 people.
Where is Advarra based?
Advarra is headquartered in Columbia, United States, in the North America region.
How does Advarra make money?
Five revenue lines are on record. CTMS Platform Subscriptions are the primary driver. The others are study Collaboration Platform, IRB Review Services, AI and Data Platform (Braid) and professional Services.
Who are Advarra's main competitors?
Direct peers on record are Veeva Systems, Medidata (Dassault Systèmes), WCG (WIRB-Copernicus Group), Clario (formerly ERT) and Signant Health. Broad incumbents are Oracle Health Sciences (Clinical One) and IQVIA Technologies. Emerging players are Florence Healthcare and Castor. ICON plc is listed as an others.
Does Advarra have an API?
Yes. Advarra provides a Study Collaboration platform that connects sponsors, CROs, and research sites with integrated eClinical technologies. The platform offers single sign-on (SSO) access to multiple systems including EDC, eConsent, IRT/RTSM, eCOA, payments, and patient engagement tools. The platform is used by more than 225,000 study team members. The CTMS integrations support API connections for linking with various enterprise systems including eRegulatory, eIRB, EDC, and participant payments.
What industry is Advarra in?
Advarra's product category is Clinical Trial Management Software. Its primary akta.pro industry code is HLAGAAAA, Clinical CROs (Phase I–IV), with a secondary code of HLAGAAAI, Patient Recruitment, Site Feasibility & Trial Enablement CROs. Its NAICS code is 541511 and its SIC code is 7372.