MDoloris Medical Systems
MDoloris Medical Systems designs and manufactures ECG-derived parasympathetic tone monitoring devices (ANI, NIPE, PTA) for objective pain and nociception assessment in surgical, ICU, NICU, and veterinary settings across 53 countries.
- Company typePrivate
- Founded2010
- HeadquartersLoos, France
- Headcount11–50
- GTM typeB2B
- OfferingHardware or Manufacturing
What MDoloris Medical Systems does
MDoloris Medical Systems is a France-based medical device company founded in 2010, headquartered in Lille (with locations referenced in Loos), that designs, manufactures, and commercializes non-invasive monitoring devices measuring parasympathetic tone — the balance of the autonomic nervous system — from ECG signals to assess pain and nociception in patients who cannot self-report. The underlying MDoloris Technology platform computes the Analgesia Nociception Index (ANI) for adults and pediatrics (from 2 years old), the Newborn Infant Parasympathetic Evaluation (NIPE) index for neonates, and the Parasympathetic Tone Activity (PTA) index for veterinary surgery, together with an "Energy" metric representing total autonomic nervous system activity. The current product portfolio comprises the ANI Monitor V1 and the next-generation ANI Monitor V2 (standalone OR/ICU/ER nociception monitors), the NIPE Monitor V1 for NICU applications, the PTA Monitor for veterinary surgery, the ANI Guardian next-generation wearable ANI solution, and OEM modules (ANI MOC-9 integrated into Masimo root devices and ANI-MR integrated into Mindray Benevision monitors). The business model combines direct hardware sales of standalone devices to hospitals, surgical centers, ICUs/PICUs, NICUs, and veterinary clinics with OEM technology licensing into third-party monitoring platforms; pricing is quote-based, multi-year contracting with healthcare procurement, and the company markets exclusively to healthcare professionals, including via a separate US entity (mdoloris-inc.us). Distribution spans 53 countries with 8,000 devices used daily and a cumulative 800,000+ patients treated, supported by over 240 independent international scientific publications and referenced KOL endorsements from European and North American anesthesiologists; the company is private with no disclosed institutional investors other than the funding history described below, and is led by founder and chief executive officer Fabien Pagniez, with Ignacio Gonzalez serving as chief medical officer.
MDoloris Medical Systems firmographics
Firmographics- Name
- MDoloris Medical Systems
- Legal name
- MDoloris Medical Systems
- Website
- https://mdoloris.com
- Company type
- Private
- Founded year
- 2010
- Operating status
- Operating
- Headcount range
- 11–50 employees
- Short description
- MDoloris Medical Systems designs and manufactures ECG-derived parasympathetic tone monitoring devices (ANI, NIPE, PTA) for objective pain and nociception assessment in surgical, ICU, NICU, and veterinary settings across 53 countries.
- Ownership category
- akta.pro rank
MDoloris Medical Systems industry classification
Industry- Product category
- Medical Monitoring Devices
- NAICS
- Electromedical and Electrotherapeutic Apparatus Manufacturing (334510), Medical Equipment and Supplies Manufacturing (3391)
- SIC
- Electromedical & Electrotherapeutic Apparatus (3845), Surgical & Medical Instruments & Apparatus (3841)
- akta.pro primary industry
- Vital Signs Monitoring (Multi-parameter, Spot-Check & Continuous) (HLAHACAA)
- akta.pro secondary industries
- Clinical-Grade Vital Signs Monitoring (ECG, SpO2, BP, Temp, Respiration) (HLACAPAI), Maternal, Fetal & Neonatal Monitoring (CTG, Infant Wearables) (HLAHACAF)
Keywords
Where MDoloris Medical Systems is headquartered
LocationHeadquarters
- HQ city
- Loos
- HQ country
- France
- HQ region
- Europe
Offices1 record
Markets served
MDoloris Medical Systems business model
Business model- GTM type
- B2B
- Offering type
- Hardware or Manufacturing
- Cost components
- Technology or R&D, Supply Chain, Personnel, Marketing or Sales, Operations
Revenue model
- Medical Device Sales: Sale of stand-alone medical monitoring devices including ANI Monitor V1, ANI Monitor V2, NIPE Monitor V1, PTA Monitor, and ANI Guardian wearable solution. Revenue generated from hardware sales to hospitals, clinics, and veterinary practices.
- OEM Technology Licensing: Integration of ANI technology into third-party medical monitoring platforms (Masimo root devices, Mindray Benevision monitors) through OEM partnerships, generating licensing and integration revenue.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| One time/ perpetual license | Multi-year contract | Medical monitoring devices for healthcare facilities |
Go-to-market motion2 records
Distribution channels4 records
Marketing channels4 records
MDoloris Medical Systems product offering
Product offeringCore offering
MDoloris Medical Systems designs, manufactures and commercializes proprietary medical monitoring devices that measure the parasympathetic tone of the autonomic nervous system from ECG signals to objectively assess pain and nociception in hospitalized patients. Its portfolio includes standalone ANI monitors (V1, V2), NIPE monitor for neonates, PTA monitor for veterinary use, ANI Guardian wearable, plus OEM modules integrated into Masimo and Mindray patient monitoring platforms. The technology is used in operating rooms, ICUs, NICUs, and veterinary clinics across 53 countries.
Product overview
MDoloris Medical Systems offers a portfolio of medical monitoring devices based on proprietary technology measuring parasympathetic tone through ECG-derived heart rate variability. The product line includes: standalone ANI monitors (V1 and V2) for adult and pediatric nociception monitoring in operating rooms and ICUs; OEM integrations with Masimo (ANI MOC-9) and Mindray (ANI-MR) platforms; NIPE Monitor V1 for neonatal NICU applications; PTA Monitor for veterinary surgery; and ANI Guardian as a next-generation wearable solution. All products share the core MDoloris Technology platform delivering ANI/NIPE/PTA indexes (measuring parasympathetic activity) and Energy metrics (global ANS activity) to assess pain, nociception, and patient comfort across the care continuum from neonatal to adult patients.
Differentiator
Problem solved
Functional benefit
Brands
- MDoloris Technology: The core technology platform for assessing parasympathetic tone and monitoring pain/nociception in patients
- ANI (Analgesia Nociceptor Index)
- NIPE (Newborn Infant Parasympathetic Evaluation)
- PTA (Parasympathetic Tone Activity)
Products and services
- ANI Monitor V2 Stand-alone nociception monitoring device for adult and pediatric patients (from 2 years old) providing ANIm (4-minute averaged) and ANIi (2-minute instantaneous) parasympathetic tone measurements, Energy metric, Quality Signal indicator, ECG monitoring, and respiratory pattern visualization. Used by anesthesiologists and perioperative teams in OR, ICU and PICU settings.
- ANI Monitor V1 Classic stand-alone nociception monitoring solution providing ANI (Analgesia Nociceptor Index) measurements for assessing pain and nociception in hospitalized adult and pediatric patients.
- NIPE Monitor V1 Neonatal intensive care unit (NICU) monitoring solution evaluating and monitoring the parasympathetic part of the Autonomic Nervous System of newborns and premature infants to ensure total comfort and control nociception at critical early ages.
- PTA Monitor Veterinary monitoring solution using PTA (Parasympathetic Tone Activity) index for optimal analgesia management during animal surgery, enabling better revival and recovery for animals that cannot verbally communicate pain.
- ANI Guardian Next Generation wearable ANI solution providing nociception monitoring in a wearable format for flexible monitoring applications across various clinical settings.
- ANI MOC-9 OEM partnership product integrating MDoloris ANI measurement technology into Masimo root devices for seamless nociception monitoring within the Masimo patient monitoring ecosystem.
- ANI-MR OEM partnership product integrating MDoloris ANI technology with Benevision Mindray monitors, enabling nociception monitoring within Mindray's patient monitoring platform.
Quantifiable outcome
- 34% reduction in opioids used during treatment
- +4 more outcomes
Companies that use MDoloris Medical Systems
Customer profileNamed customers4 records
Segments5 records
Ideal customer profiles5 records
MDoloris Medical Systems technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Integration2 records
AI capability2 records
Feature6 records
MDoloris Medical Systems partnerships and signals
Strategic signalPartnerships
Two partnerships are on record, tiered core.
- MasimocoreOEM Partnership through which MDoloris integrated its ANI measurement technology (ANI MOC-9) into the Masimo root device platform. This partnership enables Masimo's extensive hospital monitoring customer base to access ANI nociception monitoring capabilities through their existing Masimo infrastructure.
- MindraycoreOEM Partnership integrating ANI-MR technology with Benevision Mindray monitors. This integration brings ANI nociception monitoring to Mindray's patient monitoring platform serving hospitals worldwide.
Scale indicators7 records
Recent moves6 records
Expansion highlights6 records
MDoloris Medical Systems competitors and assessment
Company assessmentBroad incumbents
- Nihon Kohden: Japanese patient monitoring OEM with strong installed base in OR and ICU; comparable as a multi-parameter monitor vendor whose platforms overlap MDoloris's hospital customer base.
- Masimo: Global patient monitoring incumbent and MDoloris's OEM partner; overlapping through SedLine (PSI) for anesthesia depth and broader multi-parameter monitoring, with both partnership and competitive overlap.
- Mindray: One of the world's largest patient monitor OEMs and MDoloris's other OEM partner; comparable in hosting ANI on Benevision monitors while also offering its own depth-of-anesthesia and hemodynamic monitoring portfolio.
- Drägerwerk: German anesthesia workstation and patient monitoring incumbent with integrated depth-of-anesthesia monitoring; comparable as a comprehensive OR/ICU monitoring supplier whose platforms could host or compete with ANI.
- GE HealthCare: Major patient monitoring and anesthesia delivery OEM serving hospitals globally; relevant as a large incumbent whose monitoring platforms intersect MDoloris's OR/ICU/NICU use cases.
- Philips: Global patient monitoring and ICU solutions incumbent; comparable in serving the same hospital monitoring customers MDoloris targets, with broader portfolio depth.
- Medtronic: Large medical device incumbent with patient monitoring and perioperative care offerings; comparable as an established player whose scale and R&D could pressure MDoloris in hospital monitoring markets.
Emerging players
- CNSystems: Austrian developer of non-invasive hemodynamic monitoring (CNAP, Task Force Monitor); comparable as a smaller European specialist in continuous, non-invasive perioperative patient monitoring.
Direct peers
- Medasense Biometrics: Israel-based developer of the NOL (Nociception Level) index and PMD-200 monitor, the closest direct competitor to MDoloris in ECG/photoplethysmography-based nociception monitoring for surgical anesthesia.
- Quantium Medical: Spanish developer of qNOX and qCON indices for analgesia and hypnosis monitoring based on EEG—comparable as a dedicated anesthesia-depth/nociception monitoring company competing for the same OR clinical workflow.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat6 records
Key risks6 records
Key highlights6 records
Customer concentration
MDoloris Medical Systems social profiles
Digital presenceMDoloris Medical Systems financial estimates
Financial estimateRevenue estimate
Valuation estimate
MDoloris Medical Systems leadership team
Management profileNumber of profiles
Profiles2 records
MDoloris Medical Systems funding detail
Funding detailFunding overview
Funding rounds3 records
Investors5 records
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
MDoloris Medical Systems M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about MDoloris Medical Systems
What does MDoloris Medical Systems do?
MDoloris Medical Systems designs, manufactures and commercializes proprietary medical monitoring devices that measure the parasympathetic tone of the autonomic nervous system from ECG signals to objectively assess pain and nociception in hospitalized patients. Its portfolio includes standalone ANI monitors (V1, V2), NIPE monitor for neonates, PTA monitor for veterinary use, ANI Guardian wearable, plus OEM modules integrated into Masimo and Mindray patient monitoring platforms. The technology is used in operating rooms, ICUs, NICUs, and veterinary clinics across 53 countries.
Is MDoloris Medical Systems a public or private company?
MDoloris Medical Systems is a private company. It is classified as venture growth investor backed and is currently operating.
When was MDoloris Medical Systems founded?
MDoloris Medical Systems was founded in 2010. It employs 11 to 50 people.
Where is MDoloris Medical Systems based?
MDoloris Medical Systems is headquartered in Loos, France, in the Europe region.
How does MDoloris Medical Systems make money?
Two revenue lines are on record. Medical Device Sales are the primary driver. The others are OEM Technology Licensing.
Who are MDoloris Medical Systems's main competitors?
Broad incumbents on record are Nihon Kohden, Masimo, Mindray, Drägerwerk, GE HealthCare, Philips and Medtronic. CNSystems is listed as an emerging player. Direct peers are Medasense Biometrics and Quantium Medical.
Does MDoloris Medical Systems have an API?
No public API is recorded for MDoloris Medical Systems.
What industry is MDoloris Medical Systems in?
MDoloris Medical Systems's product category is Medical Monitoring Devices. Its primary akta.pro industry code is HLAHACAA, Vital Signs Monitoring (Multi-parameter, Spot-Check & Continuous), with a secondary code of HLACAPAI, Clinical-Grade Vital Signs Monitoring (ECG, SpO2, BP, Temp, Respiration). Its NAICS code is 334510 and its SIC code is 3845.