EndoTheia
EndoTheia is a Nashville-based medical device company developing independently steerable flexible endoscopic tools — including kidney stone baskets, laser fiber guides, and millimeter-scale digital endoscopes — using proprietary micromachined concentric tube technology licensed from Vanderbilt University, targeting urology, gastroenterology, and ENT markets.
- Company typePrivate
- Founded2018
- HeadquartersNashville, United States
- Headcount11–50
- GTM typeB2B
- OfferingHardware or Manufacturing
What EndoTheia does
EndoTheia, Inc. is a privately held medical device company founded in August 2018 as a spinout of Vanderbilt University and headquartered in Nashville, Tennessee. The company develops next-generation flexible endoscopic devices based on proprietary micromachined concentric tube technology, which enables independently steerable tools at millimeter and sub-millimeter scales — capabilities the company describes as world-firsts in flexible endoscopy. EndoTheia serves the urology, gastroenterology, and otolaryngology markets, with primary clinical focus on ureteroscopic kidney stone treatment and laser lithotripsy.
The company's commercial product portfolio centers on three devices: the FlexStone Basket (the world's first independently steerable kidney stone retrieval basket, 2.1F tipless Nitinol design compatible with all third-party scopes), the FlexStone Fiber Guide (the world's first independently steerable laser fiber guide for stone dusting, popcorning, and fragmentation), and TheiaScope (a millimeter-scale steerable digital flexible endoscope with CMOS imaging, outer diameter down to 0.97mm and up to ±360° deflection). All three products leverage the same core micromachined concentric tube architecture, which the company licenses exclusively from Vanderbilt University CTTC (agreement August 2020). Patents protecting steerable sheath, stone capture, lithotripsy, and modular biliary platforms have been filed or granted.
EndoTheia is pre-commercial. Revenue is not disclosed and products are not yet FDA-cleared as of June 2026, though ISO 13485 certification was achieved that month and the company has FDA Breakthrough Device Designation plus a Q-Sub-aligned 510(k) pathway. Revenue mechanics are expected to be hardware sales of Class II medical devices via direct enterprise engagement with hospitals and surgical centers, supplemented by technology licensing. Go-to-market is executed through a strategic partnership with Nissha Medical Technologies (announced November 2023) for manufacturing and global commercial distribution, plus direct KOL engagement at conferences such as AUA, Digestive Disease Week, and the Hamlyn Symposium. Cumulative capital raised is approximately $12.4M+ across NIH/NIDDK/NIDCD/NIBIB grants (~$8.1M), LaunchTN SBIR matching ($600K), a $4.7M capital round (December 2023), and a subsequent $500K round (September 2024).
EndoTheia firmographics
Firmographics- Name
- EndoTheia
- Legal name
- EndoTheia, Inc.
- Website
- https://endotheia.com
- Company type
- Private
- Founded year
- 2018
- Operating status
- Operating
- Headcount range
- 11–50 employees
- Short description
- EndoTheia is a Nashville-based medical device company developing independently steerable flexible endoscopic tools — including kidney stone baskets, laser fiber guides, and millimeter-scale digital endoscopes — using proprietary micromachined concentric tube technology licensed from Vanderbilt University, targeting urology, gastroenterology, and ENT markets.
- Ownership category
- akta.pro rank
EndoTheia industry classification
Industry- Product category
- Flexible Endoscopic Medical Devices
- NAICS
- Surgical and Medical Instrument Manufacturing (339112), Electromedical and Electrotherapeutic Apparatus Manufacturing (334510)
- SIC
- Surgical & Medical Instruments & Apparatus (3841), Electromedical & Electrotherapeutic Apparatus (3845)
- akta.pro primary industry
- Endoscopy Systems & Accessories (Scopes, Cameras, Light Sources, Insufflation) (HLAHADAB)
- akta.pro secondary industries
- Endoscopic Therapeutic & Access Devices (Trocars, dilators, biopsy/ablation tools) (HLAHADAN), Endourology & Minimally Invasive Urologic Surgery (HLAKAOAF)
Keywords
Where EndoTheia is headquartered
LocationHeadquarters
- HQ city
- Nashville
- HQ country
- United States
- HQ region
- North America
Offices1 record
Markets served
EndoTheia business model
Business model- GTM type
- B2B
- Offering type
- Hardware or Manufacturing
- Cost components
- Personnel, Technology or R&D, Operations, Marketing or Sales, Supply Chain, Infrastructure
Revenue model
- Medical Device Hardware Sales: Revenue generated from sale of FDA-cleared medical devices including FlexStone Basket and FlexStone Fiber Guide for urological procedures. Company is progressing toward commercial rollout with ISO 13485 certification achieved in June 2026.
- Technology Licensing: Licensing of proprietary micromachined concentric tube technology to other medical device manufacturers for integration into their products. Exclusive license secured from Vanderbilt University CTTC in August 2020.
Go-to-market motion3 records
Distribution channels3 records
Marketing channels6 records
EndoTheia product offering
Product offeringCore offering
EndoTheia develops and manufactures flexible endoscopic medical devices that enable independent tool steering at millimeter and sub-millimeter scales using proprietary micromachined concentric tube technology. Its commercial product line consists of the FlexStone steerable kidney stone basket, the FlexStone steerable laser fiber guide for lithotripsy, and the TheiaScope steerable digital flexible endoscope, sold to hospitals, surgical centers, and specialist surgeons in urology, gastroenterology, and ENT.
Product overview
EndoTheia is a medical device company offering a portfolio of novel endoscopic steering technology products. The company's core technology separates tool motion from flexible endoscope motion, enabling independent tool steering at millimeter and sub-millimeter scales. The product portfolio includes three main offerings: the FlexStone Basket (the world's first independently steerable stone retrieval basket), the FlexStone Fiber Guide (the world's first independently steerable laser guide), and the TheiaScope (a millimeter-scale steerable digital endoscope). All products leverage EndoTheia's proprietary micromachined concentric tube/sheath technology to enable steerability in medical devices that historically could not be actively steered.
Differentiator
Problem solved
Functional benefit
Products and services
- FlexStone Basket The FlexStone Basket is the world's first independently steerable stone retrieval basket for kidney stone procedures, featuring independent tip steerability and a 2.1F tipless Nitinol basket design compatible with all third-party scopes. It enables precise navigation in challenging anatomies for difficult-to-reach bladder, ureteral, and renal stones and is intended for urologists performing ureteroscopy.
- FlexStone Fiber Guide The FlexStone Fiber Guide is the world's first independently steerable laser guide for laser lithotripsy, offering independent control of laser fibers for efficient stone dusting, popcorning, and fragmentation workflows. It is fully compatible with third-party scopes and laser fibers and is intended for urologists and endourologists performing laser lithotripsy.
- TheiaScope TheiaScope is a millimeter-sized steerable digital flexible endoscope for minimally invasive diagnostics, featuring proprietary EndoTheia technology for steerable digital visualization at millimeter and sub-millimeter scales with CMOS digital imaging, scope lengths up to 2m, and tunable tip deflection up to 270 degrees. It is intended for clinicians performing flexible endoscopy in ENT, biliary, and other anatomies requiring millimeter-scale access.
Quantifiable outcome
- Successful clinical trial completion with all primary and secondary endpoints met for biliary disease treatment
- +3 more outcomes
Companies that use EndoTheia
Customer profileNamed customers2 records
Segments5 records
Ideal customer profiles3 records
EndoTheia technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Feature6 records
EndoTheia partnerships and signals
Strategic signalPartnerships
Three partnerships are on record, tiered core.
- Robert Webster IIIcoreSurgical robotics pioneer with over 75 patents, inventor and engineer who has significantly advanced surgical robotics through two startups including EndoTheia. Collaborations aim to bring innovative medical devices from idea to market, enhancing patient care worldwide. In May 2025, his devices successfully removed tumors in six patients.
- Nissha Medical TechnologiescoreStrategic partnership with Nissha Medical Technologies (NMT) announced November 2023 to leverage NMT's extensive design, development, and manufacturing expertise in furthering EndoTheia's mission to improve standards of care in flexible endoscopy. NMT CEO Brandon Hoffman serves as EndoTheia Board Member, and CFO/COO Michael Memminger joined EndoTheia Board in December 2025. NMT provides commercial infrastructure including booth presence at MD&M West and joint panel presentations at DeviceTalks events.
- Vanderbilt University Center for Technology Transfer and CommercializationcoreExclusive license negotiated with Vanderbilt University CTTC to commercialize underlying micromachined concentric tube technology originally developed at Vanderbilt. Robert Webster III served as faculty at Vanderbilt. EndoTheia incubated at Vanderbilt University from 2018 to 2020 before formal operations began. Clinical trials conducted at Vanderbilt University Medical Center.
Scale indicators13 records
Recent moves8 records
Expansion highlights7 records
EndoTheia competitors and assessment
Company assessmentBroad incumbents
- Boston Scientific: Major medical device incumbent with substantial urology and endoscopy portfolios including stone management devices (LithoVue ureteroscope, Dakota stone retrieval devices). Direct competitive overlap with EndoTheia's FlexStone products in ureteroscopy and kidney stone management.
- Olympus Corporation: Global leader in flexible endoscopy with comprehensive GI, urological, and surgical endoscope platforms. Comparable to EndoTheia's TheiaScope digital endoscope and endoscopic accessory offerings across multiple specialties.
- Karl Storz: Premium endoscopy systems manufacturer offering flexible and rigid endoscopes across urology, gastroenterology, and ENT. Competes with EndoTheia's TheiaScope in miniaturized visualization and with steerable accessories in working-channel tools.
- Coloplast: Urology-focused medical device company with stone management products and surgical urology portfolio. Competitor in endourology space where EndoTheia's FlexStone products are commercialized.
- Stryker: Large diversified medical device company with endoscopy, surgical instruments, and urology offerings. Broad incumbent whose endoscopy division overlaps with EndoTheia's flexible endoscopic tools across multiple specialties.
- Hologic: Women's health and surgical medical device company with gynecology/surgical endoscopy products. Adjacent competitor in specialty endoscopic procedures where EndoTheia's technology could expand.
- Medtronic: Global medical device conglomerate with substantial GI, urology, and surgical portfolios. Broad incumbent whose GI endoscopy and endourology divisions overlap with multiple EndoTheia product lines.
Direct peers
- Cook Medical: Direct competitor in urological stone management with comprehensive portfolio of ureteroscopes, stone retrieval baskets, and laser lithotripsy accessories. Competes head-to-head with EndoTheia's FlexStone Basket and Fiber Guide in kidney stone procedures.
Emerging players
- Ambu: Single-use endoscopy innovator challenging reusable endoscope incumbents. Emerging player in flexible endoscopy with potential overlap to EndoTheia's TheiaScope digital visualization platform.
- Intuitive Surgical: Robotic surgery leader (da Vinci) extending into flexible and natural orifice procedures. Relevant as a longer-horizon competitor in robotic and digitally-enabled endoscopic surgery where EndoTheia's steerable technology could compete or partner.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat5 records
Key risks5 records
Key highlights7 records
Customer concentration
EndoTheia social profiles
Digital presenceEndoTheia compliance and trust
Trust signalCompliance2 records
EndoTheia financial estimates
Financial estimateRevenue estimate
Valuation estimate
EndoTheia leadership team
Management profileNumber of profiles
Profiles9 records
EndoTheia funding detail
Funding detailFunding overview
Funding rounds2 records
Investors2 records
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
EndoTheia M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about EndoTheia
What does EndoTheia do?
EndoTheia develops and manufactures flexible endoscopic medical devices that enable independent tool steering at millimeter and sub-millimeter scales using proprietary micromachined concentric tube technology. Its commercial product line consists of the FlexStone steerable kidney stone basket, the FlexStone steerable laser fiber guide for lithotripsy, and the TheiaScope steerable digital flexible endoscope, sold to hospitals, surgical centers, and specialist surgeons in urology, gastroenterology, and ENT.
Is EndoTheia a public or private company?
EndoTheia is a private company. It is classified as founder individual operated bootstrapped and is currently operating.
When was EndoTheia founded?
EndoTheia was founded in 2018. It employs 11 to 50 people.
Where is EndoTheia based?
EndoTheia is headquartered in Nashville, United States, in the North America region.
How does EndoTheia make money?
Two revenue lines are on record. Medical Device Hardware Sales are the primary driver. The others are technology Licensing.
Who are EndoTheia's main competitors?
Broad incumbents on record are Boston Scientific, Olympus Corporation, Karl Storz, Coloplast, Stryker, Hologic and Medtronic. Cook Medical is listed as a direct peer. Emerging players are Ambu and Intuitive Surgical.
Does EndoTheia have an API?
No public API is recorded for EndoTheia.
What industry is EndoTheia in?
EndoTheia's product category is Flexible Endoscopic Medical Devices. Its primary akta.pro industry code is HLAHADAB, Endoscopy Systems & Accessories (Scopes, Cameras, Light Sources, Insufflation), with a secondary code of HLAHADAN, Endoscopic Therapeutic & Access Devices (Trocars, dilators, biopsy/ablation tools). Its NAICS code is 339112 and its SIC code is 3841.