What VB-Tech does

VB Tech S.A.S., headquartered in Aix-en-Provence, France, develops patient-specific digital brain twin technology for neurological and neurosurgical applications. The company's flagship product, BrainXplore, is a browser-based platform that ingests multimodal neuroimaging data (MRI, DTI, EEG, MEG, SEEG) and produces biophysically grounded whole-brain simulations using its exclusively licensed core engine, The Virtual Brain (TVB). Its lead clinical module, VEP (Virtual Epileptic Patient), provides clinical decision support for drug-resistant epilepsy by identifying epileptogenic zones with a 29% improvement over standard of care and enabling virtual surgery planning; the technology is currently being validated in the EPINOV trial, the largest epilepsy-surgery clinical study to date (13 centers, 356 patients), with an FDA submission in progress.

The company operates a Hub-model distribution strategy: leading academic medical centers (APHM Marseille as Hub #0, UPMC Pittsburgh as Hub #1, UC Davis as Hub #3) install BrainXplore on-premises, receive training, and serve as clinical reference sites for research and investigational use. The current revenue posture is largely pre-commercial: Hubs receive free research access, monetizable streams are expected to come from software subscriptions, clinical module licensing (VEP), pharma partnership services for Alzheimer/Parkinson's/M/S/schizophrenia, and the BrainXplore Clinical Fellowship Program. Leadership combines academic founders (CSO Prof. Viktor Jirsa, EPINOV lead Prof. Fabrice Bartolomei) with industrial scale-up operators (CEO Serge De Senti from January 2026, Deputy CEO Jean-Marc Ferrier, CTO Eric Guiffard, CGO Philippe Schulz), and the company has only one disclosed external capital event — a $519,167 round from Rise Partners in January 2025.

Name

VB-Tech

Legal name

VB Tech S.A.S.

Website

https://virtualbraintech.com

Company type

Private

Founded year

2021

Operating status

Operating

Headcount range

1–10 employees

Short description

VB Tech (VB Tech S.A.S.) is a French deep-tech company developing patient-specific digital brain twins via its BrainXplore platform, serving academic neurosurgery centers and pharmaceutical partners — initially targeting drug-resistant epilepsy through its clinically validated VEP module.

Ownership category

akta.pro rank

Product category

Computational Neuroscience Software

NAICS

Computer Systems Design and Related Services (54151)

SIC

Services-Computer Integrated Systems Design (7373)

akta.pro primary industry

Behavioral Health & Neurocognitive Therapeutics (Digital) (HLACANAI)

Keywords

• Digital brain twin
• Neurological simulation software
• Epilepsy surgery planning
• Computational neuroscience platform
• Patient-specific brain modeling

Headquarters

HQ city

Marseille

HQ country

France

HQ region

Europe

Offices4 records

Markets served

GTM type

B2B

Offering type

Software

Cost components

Personnel, Technology or R&D, Marketing or Sales, Operations, Infrastructure

Revenue model

1. Software Platform Licensing (BrainXplore): BrainXplore platform offered for research, education, and investigational clinical studies. Hubs receive free access for research. Revenue model likely centers on software licensing/subscription for clinical deployment post-regulatory validation.
2. Clinical Module Licensing (VEP Module): VEP (Virtual Epileptic Patient) module designed as a clinical decision-support tool for neurosurgical planning in drug-resistant epilepsy. Expected to generate revenue through clinical licensing as regulatory approval is obtained.
3. Pharmaceutical Industry Partnerships: Clinical modules for other brain diseases (Alzheimer's, Parkinson's, M/S, Schizophrenia) to be developed in partnership with pharmaceutical industry to support precision drug development.
4. Clinical Fellowship Program: BrainXplore Clinical Fellowship Program — an immersive experience for neurologists, neurosurgeons, and researchers, with 5 fellowship slots remaining through end of 2026.

Go-to-market motion2 records

Distribution channels1 record

Marketing channels7 records

Core offering

VB Tech provides the BrainXplore platform, a browser-based system that generates patient-specific digital brain twins from multimodal neuroimaging data (MRI, DTI, EEG, SEEG, MEG) to simulate whole-brain dynamics. The platform's first clinical module, the Virtual Epileptic Patient (VEP), supports surgical planning for drug-resistant epilepsy by identifying epileptogenic zones and enabling virtual testing of resection strategies before surgery. Additional clinical modules for Alzheimer's, Parkinson's, multiple sclerosis, and schizophrenia are in development in partnership with pharmaceutical companies.

Product overview

VB Tech provides a modular brain simulation platform centered on BrainXplore, a browser-based platform that generates patient-specific digital brain twins from multimodal neuroimaging data. The core Virtual Brain Twin technology simulates whole-brain dynamics. The VEP (Virtual Epileptic Patient) module targets drug-resistant epilepsy for surgical planning. Additional modules for Alzheimer's, Parkinson's, M/S, and schizophrenia are in development in partnership with pharmaceutical industry for precision drug development.

Differentiator

Problem solved

Functional benefit

Brands

• VEP – Virtual Epileptic Patient™: Clinical decision-support module for patients with drug-resistant epilepsy that simulates the propagation of epileptic activity across the brain network using patient-specific neuroimaging and intracranial EEG data.
• BrainXplore™

Products and services

• BrainXplore Platform Browser-based digital brain twin platform that generates patient-specific virtual brain models from multimodal neuroimaging data. Provides automated preprocessing, personalized whole-brain simulations, advanced inference modules, and an interactive 3-D viewer for clinicians and researchers in neurology and neuroscience.
• VEP - Virtual Epileptic Patient Module Clinical decision-support module for drug-resistant epilepsy patients that uses patient-specific neuroimaging and intracranial EEG (SEEG) data to simulate epileptic activity propagation across the brain network. Identifies epileptogenic zones by comparing simulated seizure dynamics to recorded data and enables virtual testing of resection strategies before surgery.

Quantifiable outcome

• 29% improvement in identification of epileptogenic zones vs standard methods (retrospective study on 53 patients)
• +4 more outcomes

Named customers1 record

Segments5 records

Ideal customer profiles2 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration1 record

AI capability4 records

Feature9 records

Partnerships

Eleven partnerships are on record, tiered core, secondary and minor.

• UPMC (University of Pittsburgh Medical Center)coreChannel Partner/ Reseller/ Distributor · 7 March 2025UPMC Pittsburgh is Hub #1, an official BrainXplore ambassador. VB Tech installed the BrainXplore platform and trained clinicians and researchers to use it in daily workflows. Led by Jorge A. González-Martínez, MD, PhD. Represents VB Tech's US market entry.
• UC DaviscoreChannel Partner/ Reseller/ Distributor · 7 March 2025UC Davis is Hub #3, an official BrainXplore ambassador. VB Tech installed the BrainXplore platform and trained clinicians and researchers to use it in daily workflows. Led by Nigel Paul Pedersen, MD. Second US-based clinical hub.
• Aix-Marseille UniversitécoreStrategic or Co-development Partner · 1 January 2021Aix-Marseille Université is VB Tech's primary academic research partner. The university hosts the Institut de Neurosciences des Systèmes (INS), where The Virtual Brain technology was developed. CEO Serge De Senti is an associate professor at the university, and Lisa Otten serves at the interface of research and VB Tech. The university provides scientific talent, research infrastructure, and institutional credibility.
• Institut de Neurosciences des Systèmes (INS)coreStrategic or Co-development PartnerINS is a research center within Inserm and Aix-Marseille University focused on brain dynamics and disorders like epilepsy. The Virtual Brain Technologies are based on research conducted at INS. Director Viktor Jirsa leads the institute, and Jan-Paul Triebkorn collaborates with VB Tech as INS personnel.
• Assistance Publique-Hôpitaux de Marseille (APHM)coreStrategic or Co-development PartnerThe public hospital system of Marseille provides clinical research infrastructure and patient access. Prof. Fabrice Bartolomei leads the Epileptology department at APHM and co-founded VB Tech. APHM serves as Hub #0, the primary clinical reference center. APHM sponsors the EPINOV clinical trial.
• CodemartcoreTechnology or IntegrationCodemart is a software engineering firm based in Cluj-Napoca, Romania, specializing in neuroscience applications and open-source brain simulators. Lia Domide, Codemart's managing partner, leads all product development at VB Tech and developed The Virtual Brain platform.
• Centre national de la recherche scientifique (CNRS)secondaryStrategic or Co-development PartnerCNRS is France's largest public research organization. Listed as a partner with VB Tech, contributing to the scientific ecosystem supporting Virtual Brain technology development.
• Institut National de la Santé et de la Recherche Médicale (INSERM)secondaryStrategic or Co-development PartnerINSERM is a French public research institute dedicated to human health and medical science. INS hosts the Institut de Neurosciences des Systèmes where Virtual Brain research is conducted, and co-founder Viktor Jirsa serves as director.
• Hospices Civils de Lyon (HCL)secondaryStrategic or Co-development PartnerHCL of Lyon, represented by Prof. Sylvain Rheims, collaborates on the EPINOV clinical trial alongside APHM. One of 13 clinical centers participating in the largest epilepsy surgery clinical trial to date.
• EPINOV Consortium (13 Clinical Centers)coreStrategic or Co-development PartnerEPINOV is the largest clinical trial in epilepsy surgery to date, coordinated by Prof. Fabrice Bartolomei (APHM) and Prof. Sylvain Rheims (HCL Lyon), involving 13 leading clinical centers and 356 drug-resistant epilepsy patients. Validates VB Tech's VEP technology clinically.
• Human Brain Project / EBRAINSminorStrategic or Co-development PartnerViktor Jirsa is a key figure in EU flagships Human Brain Project and EBRAINS, which bridge neuroscience research and clinical application. These EU initiatives support the broader ecosystem of brain research that underpins VB Tech's technology.

Scale indicators13 records

Recent moves6 records

Expansion highlights6 records

Emerging players

• Pixyl: Pixyl is an emerging AI neuroimaging vendor focused on multiple sclerosis and brain MRI analysis — overlapping with VB Tech's planned multiple sclerosis module and relevant as a focused AI-imaging competitor pursuing similar neurology indications.

Direct peers

• Surgical Theater: Surgical Theater provides VR/3D surgical planning and visualization software used in neurosurgery — directly comparable to VB Tech's Virtual Surgery Simulation capability for pre-operative epilepsy resection planning and neurosurgical decision support.
• Perspectum: Perspectum builds quantitative MRI-based decision-support tools (e.g., LiverMultiScan, CoverScan) used in research and clinical care — a strong direct peer to VB Tech in multi-modal neuroimaging analytics for high-unmet-need neurological and chronic disease markets.
• Nicolab: Nicolab (Stroke Viewer) is an AI imaging platform for time-critical neurovascular workflows — a relevant direct peer for VB Tech in clinical decision-support software that ingests multimodal neuroimaging (CT/MRI/EEG-style inputs) to inform acute treatment decisions.
• RapidAI: RapidAI is an AI-based clinical decision-support platform for stroke and other neurovascular conditions, processing multimodal imaging to identify lesions and recommend interventions — directly comparable to VB Tech's positioning as imaging-driven SaMD for neurology.
• Omniscient Neurotechnology: Omniscient Neurotechnology (o8t / BrainKey) builds AI-powered brain mapping and connectomics software for clinical and research use — the closest direct competitor to VB Tech's Virtual Brain Twin and BrainXplore platform in patient-specific brain network modeling.

Broad incumbents

• Brainlab: Brainlab is an established incumbent in surgical planning, image-guided neurosurgery and radiotherapy software — a broader incumbent peer whose neurosurgery planning tools compete for hospital wallet alongside VB Tech's VEP module.
• Siemens Healthineers: Siemens Healthineers is a global incumbent in neuroimaging scanners, PACS and AI imaging analytics (e.g., AI-Rad Companion) — relevant as the broader incumbent whose data, scanner and imaging AI footprint competes for the same hospital decision-makers VB Tech sells into.
• GE HealthCare: GE HealthCare is a broad incumbent in MRI, PET, and AI-powered imaging analytics — comparable to VB Tech as an integrated imaging/imaging-AI provider selling into the same neurology and neurosurgery hospital customers.

Others

• Codemart: Codemart, VB Tech's core software development partner led by Lia Domide, is the external engineering organization building the Virtual Brain platform — included as an ecosystem peer because any investor should treat Codemart's bandwidth and VB Tech's reliance on it as a key vendor relationship.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks5 records

Key highlights6 records

Customer concentration

• LinkedInlinkedin.com/company/vb-tech-virtual-brain-technologies

Compliance2 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles13 records

Funding overview

Funding rounds1 record

Investors1 record

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about VB-Tech