TriAltus Bioscience

What TriAltus Bioscience does

TriAltus Bioscience, LLC is a Birmingham, Alabama-based specialty biotechnology company that develops and sells recombinant protein enzymes and custom protein production services to academic and industrial life-science customers. The company was founded in 2017 and operates with an 11–50 person team, serving research teams working in drug discovery, genomics, diagnostics, synthetic biology, and standard molecular biology workflows.

Name

TriAltus Bioscience

Legal name

Trialtus Bioscience, LLC

Website

https://trialtusbioscience.com

Company type

Private

Founded year

2017

Operating status

Operating

Headcount range

11–50 employees

Short description

TriAltus Bioscience is a Birmingham, Alabama-based biotech company that sells recombinant enzymes and custom protein production services for academic and industrial life-science research, powered by its proprietary CLīM single-step purification platform.

Ownership category

akta.pro rank

Product category

Life Sciences Reagents

NAICS

Biological Product (except Diagnostic) Manufacturing (325414), Scientific Research and Development Services (5417), In-Vitro Diagnostic Substance Manufacturing (325413)

SIC

Biological Products, (No Disgnostic Substances) (2836), Services-Commercial Physical & Biological Research (8731)

akta.pro primary industry

Reagents, Chemicals & Assay Kits (Buffers, Antibodies, ELISA, Enzymes) (HLAGAIAI)

akta.pro secondary industry

Protein Engineering & Directed Evolution Platforms (enzyme/therapeutic protein optimization) (HLAAAIAC)

Keywords

• Recombinant enzyme reagents
• Protein purification technology
• Affinity chromatography systems
• CRISPR enzyme products
• Custom protein production

Headquarters

HQ city

Birmingham

HQ country

United States

HQ region

North America

Offices2 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Personnel, Technology or R&D, Operations, Supply Chain, Marketing or Sales

Revenue model

1. Catalog Enzyme Products: Sale of pre-formulated recombinant enzyme products including CRISPR nucleases (Cas9, Cas12a, Cas12b), polymerases, proteases, transposases, and other molecular biology enzymes. Products are sold in various sizes with volume-based pricing.
2. Custom Protein Production Services: Development of custom proteins using proprietary CLīM system for projects with clear paths to scalable production. Includes Pilot2Partnership program offering free pilots for qualifying projects.
3. Contract Manufacturing: ISO 13485-compliant production of research- or diagnostic-grade enzymes with batch-to-batch consistency and flexible supply options.

Pricing tiers

Go-to-market motion2 records

Distribution channels2 records

Marketing channels4 records

Core offering

TriAltus Bioscience manufactures and sells recombinant enzyme products (CRISPR nucleases, polymerases, proteases, transposases, recombinases) and offers custom protein production services under its proprietary CLīM™ (CL7/Im7) single-step affinity-purification platform. Catalog enzymes are sold via self-serve e-commerce with publicly listed unit prices, while custom and ISO 13485-grade diagnostic protein work is delivered through a Pilot2Partnership program with 4–6 week turnaround.

Differentiator

Problem solved

Functional benefit

Brands

• CLīM: Proprietary purification technology platform delivering ultra-pure, high-performance proteins in a single purification step using CL7/Im7 affinity system.
• Pilot2Partnership

Products and services

• Recombinant Enzyme Catalog A catalog of pre-formulated recombinant enzymes — including CRISPR nucleases (Cas9, Cas12a, Cas12b), polymerases (Phi29), proteases (SUMO, PreScission), transposases (Tn5), TAT-Cre recombinase, and Sortase A heptamutant — produced using the CLīM platform and sold in unit-based sizes (e.g., 3,000 or 10,000 units) via the company's e-commerce site. Targeting life-science research and diagnostics teams needing ultra-pure, high-activity specialty enzymes.
• Custom Protein Production Services (Pilot2Partnership) Custom recombinant protein development service using the proprietary CLīM system for projects with a clear path to scalable production. Includes a no-cost pilot phase for qualifying projects, after which customers transition to bulk or recurring production with a 4–6 week turnaround. Targeting research labs and biotech companies that need to outsource enzyme production without sacrificing quality or scalability.
• Contract Manufacturing (ISO 13485) ISO 13485-compliant contract manufacturing of research- or diagnostic-grade enzymes with batch-to-batch consistency, flexible supply options, and full QC data packages. Targeting diagnostics manufacturers and assay developers that require regulatory documentation and traceability for clinical-grade reagents.

Quantifiable outcome

• 15% lower average cost vs conventional suppliers
• +3 more outcomes

Named customers1 record

Segments4 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature4 records

Partnerships

Eleven partnerships are on record, tiered core and minor.

• Dr. Jennifer Doudna's Lab at UC BerkeleycoreStrategic or Co-development Partner · 1 January 2021Scientists in Dr. Doudna's lab (Nobel Prize in Chemistry 2020, co-inventor of CRISPR-Cas9) have produced 100+ CRISPR enzymes using TriAltus' CLīM purification system since 2021. This collaboration has generated peer-reviewed publications in Nature Biotechnology (2024) and Nucleic Acids Research (2025), validating the technology in high-profile academic research.
• The University of Alabama at Birmingham (UAB)coreTechnology or IntegrationTriAltus holds exclusive license agreement with UAB for CL7 tag technology, protected by US 10,759,830 B2 and additional patents pending. This intellectual property arrangement is foundational to the company's proprietary CLīM purification platform.
• AllisWell Bio Co., Ltd.minorChannel Partner/ Reseller/ DistributorRegional distributor for Taiwan market.
• American Research Products, Inc. (ARP)minorChannel Partner/ Reseller/ DistributorRegional distributor for United States market.
• AMS Biotechnology Europe Ltd (AMS BIO)minorChannel Partner/ Reseller/ DistributorRegional distributor for United Kingdom market.
• MilliporeSigma MPartner MarketplaceminorChannel Partner/ Reseller/ DistributorListed distributor through MilliporeSigma's partner marketplace platform.
• QuartzyminorChannel Partner/ Reseller/ DistributorRegional distributor partner for laboratory supplies.
• Nucleus Biotech GmbHminorChannel Partner/ Reseller/ DistributorRegional distributor for Germany market.
• CliniSciencesminorChannel Partner/ Reseller/ DistributorRegional distributor for France and Denmark markets.
• DakeweminorChannel Partner/ Reseller/ DistributorRegional distributor for China market.
• KyvobiominorChannel Partner/ Reseller/ DistributorRegional distributor for Belgium market.

Scale indicators3 records

Recent moves6 records

Expansion highlights6 records

Broad incumbents

• QIAGEN: Supplies molecular biology enzymes, sample preparation kits, and diagnostic-grade reagents, including CRISPR-related nucleases, making it a broad portfolio competitor to TriAltus' research and diagnostic enzyme offering.
• Bio-Techne: Portfolio of R&D Systems, Tocris, and ProteinSimple brands spans recombinant proteins, enzymes, and affinity purification tools, overlapping TriAltus' catalog and protein production positioning.
• Abcam: Research reagent manufacturer offering proteins, antibodies, and assay kits to academic and industrial life science buyers, with growing presence in engineered enzymes and CRISPR reagents that competes with TriAltus' catalog.
• MilliporeSigma (Sigma-Aldrich): The life science arm of Merck KGaA offering the broadest catalog of research enzymes, affinity purification resins, and bioprocessing consumables; TriAltus is even listed as a partner on the MPartner Marketplace, illustrating the supplier-cum-distributor relationship.
• Cytiva (Danaher): Provides affinity chromatography resins, ÄKTA systems, and bioprocess purification services directly relevant to TriAltus' resin-based CL7/Im7 purification business and downstream biopharma manufacturing.
• Thermo Fisher Scientific: Global life sciences platform selling Invitrogen/Thermo enzymes, protein purification resins, and custom protein services across nearly all of TriAltus' target segments at much greater scale.

Direct peers

• GenScript: Provides custom protein production, gene synthesis, and enzyme/reagent manufacturing for research and biotech customers, overlapping directly with TriAltus' Pilot2Partnership custom protein service and catalog reagents.
• New England Biolabs: Long-established molecular biology enzyme manufacturer with a catalog of restriction enzymes, polymerases, CRISPR nucleases, and protein purification reagents that directly overlaps TriAltus' product lines and target customers.
• Takara Bio: Specializes in molecular biology enzymes including CRISPR-Cas9/Cas12 reagents, NGS library prep tools, and protein expression/purification kits—directly competitive with TriAltus' CRISPR nucleases, Tn5, and CLīM purification offerings.
• Promega Corporation: Manufactures enzymes, purification reagents, and custom protein services for life science research and diagnostics, serving many of the same academic and pharma customers as TriAltus' CLīM-powered catalog.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks9 records

Key highlights6 records

Customer concentration

• LinkedInlinkedin.com/company/trialtusbioscience
• Xx.com/TriAltusBio
• Facebookfacebook.com/TriAltusBioscience

Revenue estimate

Valuation estimate

Number of profiles

Profiles2 records

Funding overview

Funding rounds2 records

Investors1 record

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about TriAltus Bioscience