What Nucleus Biotech Gmbh does

Nucleus Biotech GmbH is a privately held German life science reagent distributor and service provider headquartered in Heidelberg (registered as GmbH at Mannheim HRB 735543), founded in 2020. The company operates a multi-brand e-commerce platform curating more than 1,500 genomics research products across nine major categories — CRISPR Tools, NGS, RNA Genomics, Lentiviral Systems, RNAi, Cell Barcoding, Sample Collection, Protein Expression, and Immunogenomics — sourced from partner manufacturers including YouSeq (PCR mastermixes and NGS library quantification), BioDynami (DNA quantification, library prep kits for Illumina and Ion Torrent, magnetic beads, multiplexing primers, DNA fragmentation reagents), and Phase Genomics (Proximo Hi-C Kits for genome scaffolding and haplotype phasing). Catalog products are sold via a self-serve online storefront with publicly listed EUR pricing (typically ~110 EUR to ~8,600 EUR per SKU), while high-value items and custom services (e.g., 5'UTR sequencing at ~20,000 EUR for an 8-service package) are offered on a quotation basis. The company does not develop proprietary core technology; instead, its value proposition rests on curated domain specialization across the full genomics workflow from sample collection through sequencing library preparation, supplemented by proprietary services such as DriverMap AIR for TCR/BCR immune repertoire profiling.

The primary customer segment is academic and research institution life science researchers conducting fundamental and applied genomics, molecular biology, and cell biology work; segment messaging addresses needs for high-quality reagents, comprehensive workflow coverage, and single-source procurement across genomics experiments. The go-to-market motion is direct-to-consumer e-commerce complemented by quotation-based consultative sales for high-value items, with digital marketing channels including the website (search-optimized product categories and partner brand content) and partner-brand co-marketing. Pricing is published publicly in EUR, billing cadence is predominantly pay-as-you-go for catalog items with multi-year contracts available for custom services and large-scale kits, and the company claims global shipping reach with operations concentrated in EMEA. The Managing Director is Dr. Michael Ehret, and the company is independently owned with no parent, subsidiaries, or institutional venture investment disclosed in the source material.

Revenue mechanics are transactional catalog sales plus service revenue, with no disclosed ARR, GMV, or enterprise contract metrics in the source data. The business model is asset-light distribution: Nucleus Biotech captures spread between wholesale sourcing from upstream brand partners and retail/quote pricing to research customers, with margin upside from value-added proprietary services (custom synthesis, DriverMap AIR TCR/BCR profiling) layered on top. Operating status is confirmed active via a live e-commerce platform with current pricing and full shopping-cart/checkout functionality.

Name

Nucleus Biotech Gmbh

Legal name

Nucleus Biotech GmbH

Website

https://nucleusbiotech.com

Company type

Private

Founded year

2020

Operating status

Operating

Headcount range

1–10 employees

Short description

Nucleus Biotech GmbH is a Heidelberg, Germany-based distributor of life science research reagents and genomics services, curating 1,500+ products from partner brands across CRISPR, NGS, RNA, and immunogenomics for academic and research institution customers worldwide via direct e-commerce.

Ownership category

akta.pro rank

Product category

Life Science Research Reagents

NAICS

Research and Development in Biotechnology (except Nanobiotechnology) (541714), Research and Development in the Physical, Engineering, and Life Sciences (54171)

SIC

Wholesale-Drugs, Proprietaries & Druggists' Sundries (5122), Services-Commercial Physical & Biological Research (8731)

akta.pro primary industry

Molecular Biology & Genomics Instruments (PCR/qPCR, Sequencing, Microarrays) (HLAGAIAF)

akta.pro secondary industry

Transcriptomics & Gene Expression Profiling Services (HLAGANAE)

Keywords

• Life science reagents
• Genomics research kits
• CRISPR tools supply
• NGS library prep reagents
• Immunogenomics services

Headquarters

HQ city

Heidelberg

HQ country

Germany

HQ region

Europe

Offices1 record

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Personnel, Technology or R&D, Marketing or Sales, Operations

Revenue model

1. Product Sales: Revenue generated from the sale of life science research reagents, kits, and instruments. Products range from small consumables (e.g., DNA quantification kits at 110 EUR) to high-value items (e.g., Cas9 expression cell lines at 8,600 EUR). The company also offers services including NGS sequencing services and custom reagent synthesis.

Pricing tiers

Go-to-market motion1 record

Distribution channels1 record

Marketing channels3 records

Core offering

Nucleus Biotech curates and distributes more than 1,500 life science research reagents, kits, and instruments across 9 categories including CRISPR Tools, NGS, RNA Genomics, Lentiviral Systems, Cell Barcoding, RNAi, Protein Expression, Sample Collection, and Immunogenomics. The company sells third-party brand products (BioDynami, YouSeq, Phase Genomics) through an e-commerce storefront and offers proprietary services such as DriverMap AIR TCR/BCR immune repertoire profiling, custom sgRNA/library synthesis, and NGS sequencing services. Customers are predominantly academic and research institution life science researchers running genomics, molecular biology, and cell biology workflows.

Product overview

Nucleus Biotech GmbH is a life science research reagent and service provider based in Germany offering a comprehensive catalog of genomics tools across 9 major product categories. The portfolio includes CRISPR Tools (428 products), Cell Barcoding (65 products), Lentiviral Systems (127 products), NGS (536 products), RNA Genomics (264 products), RNAi (96 products), Protein Expression (29 products), Sample Collection (18 products), plus Immunogenomics services. The company distributes third-party brands including BioDynami, YouSeq, and Phase Genomics products, while also providing proprietary services such as DriverMap AIR TCR/BCR profiling and custom synthesis services. The catalog operates as a multi-brand platform rather than a single unified product, with offerings ranging from individual kits and reagents to complete workflow solutions.

Differentiator

Problem solved

Functional benefit

Products and services

• DriverMap AIR Services TCR and BCR immune repertoire profiling service including DNA/RNA isolation, BCR/TCR profiling (CDR3, full-length), single cell phenotyping, and data analysis. Designed for academic and institutional researchers conducting immunogenomics studies.
• dsDNA Quantification Kits BioDynami dsDNA quantification kits for Qubit fluorometer and microplate readers, available in broad range and high sensitivity formats. Priced from 110 EUR for 110 reactions.
• ssDNA Quantification Kit BioDynami single-stranded DNA quantification kit for Qubit fluorometer for use in life science research workflows.
• YouSeq NGS Multiplex DNA MasterMix High-performance PCR MasterMix designed for amplicon-based NGS library preparation, priced from 420 EUR (5 ml) to 4,720 EUR (100 ml).
• YouSeq High-Fidelity 2x MasterMix High-fidelity DNA polymerase mix for long transcripts and high GC content at ultra low error rate, priced from 398 EUR (5 ml) to 4,498 EUR (100 ml).
• NGS Library Quantification Kit qPCR-based kits for NGS library quantification, including qPCR reagents, primers, and standards for Illumina (YouSeq) and primers plus 6 standards for Illumina or Ion Torrent platforms (BioDynami).
• Proximo Hi-C Kit for Human Samples Phase Genomics proximity ligation NGS library prep kit for Hi-C sequencing enabling chromosome-scale genome scaffolding, haplotype phasing, structural/CNV detection, and TAD analysis from human samples including FFPE; pricing requires quotation.
• DNA Fragmentation Enzyme Mix BioDynami enzymatic DNA fragmentation kit for random fragmentation of genomic DNA with optional A-tailing or blunting of fragments for NGS applications.
• Magnetic Beads for DNA and RNA Purification BioDynami magnetic beads for DNA (>100 bp) and RNA (>200 nt) purification for life science research workflows.
• Multiplexing Index Primers BioDynami multiplexing index primers for the Illumina platform, available in 48-index and 96-index (Unique Dual Index) formats for NGS library multiplexing.
• DNA Ladders BioDynami DNA ladders including 20 bp, 100 bp, 1 kb, and 1 kb plus formats in ready-to-load format for gel electrophoresis workflows.
• NGS DNA Fragmentation and Library Prep Kit (Illumina) BioDynami complete NGS library prep kit with enzymatic DNA fragmentation, unique dual index primers, and PCR reagents for Illumina platform sequencing workflows.
• NGS DNA Library Prep Kit (Ion Torrent) BioDynami DNA library prep kit with indexed adaptors for Ion Torrent platform sequencing workflows.

Segments1 record

Ideal customer profiles1 record

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature1 record

Partnerships

Three partnerships are on record, tiered core.

• YouSeqcoreChannel Partner/ Reseller/ DistributorYouSeq is a key partner providing PCR mastermixes and NGS library quantification kits. Nucleus Biotech distributes YouSeq products including the NGS Multiplex DNA MasterMix and High-Fidelity PCR MasterMix product lines. These products are sold under YouSeq catalog numbers through Nucleus Biotech's e-commerce platform.
• BioDynamicoreChannel Partner/ Reseller/ DistributorBioDynami supplies DNA quantification kits, NGS library quantification kits for Illumina and Ion Torrent platforms, magnetic beads for DNA/RNA purification, multiplexing primers, and DNA fragmentation enzyme products. Nucleus Biotech distributes the complete BioDynami catalog including DNA ladders and fragmentation reagents.
• Phase GenomicscoreChannel Partner/ Reseller/ DistributorPhase Genomics provides the Proximo Hi-C Kit product line for human and microbial sample analysis, including genome scaffolding, haplotype phasing, and chromosome conformation capture. Nucleus Biotech distributes Phase Genomics proximity ligation products including Hi-C kits, FFPE modules, and associated data analysis services.

Scale indicators1 record

Recent moves6 records

Expansion highlights4 records

Direct peers

• Carl Roth GmbH + Co. KG: Karlsruhe-based German supplier with a deep, broad life science catalog including molecular biology reagents, enzymes, and lab consumables. Comparable as a domestic German reagent supplier serving academic and biotech customers via e-commerce.
• Eurofins Genomics GmbH: European genomics services and reagent provider offering sequencing, oligonucleotides, and gene synthesis. Comparable to Nucleus Biotech across the service-aside-from-reagents dimension, especially in the DACH/EMEA region.
• Jena Bioscience GmbH: German life science reagent manufacturer and supplier covering nucleotides, genomics, and molecular biology tools. Comparable as a German-headquartered genomics reagent vendor operating across both direct and reseller channels.
• BioCat GmbH: Heidelberg-based life science research reagent distributor with a catalog of genomics and proteomics tools from multiple brands. Highly comparable to Nucleus Biotech on geography (German HQ), product mix, and third-party distributor model.
• Biozol Diagnostica Vertrieb GmbH: German distributor of life science research reagents and diagnostic products covering molecular biology, cell biology, and genomics - competes directly with Nucleus Biotech for German and European academic customers with overlapping brand inventories.

Broad incumbents

• New England Biolabs (NEB): Manufacturer of enzymes and reagents for molecular biology, NGS sample prep, and CRISPR workflows. Comparable category overlap in NGS library prep, PCR mastermixes, and DNA/RNA purification reagents that Nucleus Biotech distributes.
• Promega Corporation: Manufacturer of reagents and instruments for genomics, proteomics, and cell biology applications. Comparable across PCR, NGS sample prep, and quantification reagent categories where Nucleus Biotech's distributor catalog competes.
• Integrated DNA Technologies (IDT): Global leader in DNA/RNA oligonucleotides, NGS library prep, and CRISPR reagents. Comparable to Nucleus Biotech on the genomics reagent categories it competes in, but at much broader scale and with proprietary manufacturing.
• Bio-Techne Corporation: Large life sciences tools company spanning reagents, proteins, and diagnostics including the ExoDx, R&D Systems, and BioLegend brands. Overlaps with Nucleus Biotech's portfolio breadth across genomics, proteomics, and cell biology reagents at a significantly larger scale.

Emerging players

• Twist Bioscience: Synthetic DNA and NGS target enrichment provider with growing offerings in antibody and DNA data storage. Comparable in NGS library prep, synthetic nucleic acids, and custom oligo/synthesis services that overlap with Nucleus Biotech's CRISPR and RNA Genomics lines.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat3 records

Key risks5 records

Key highlights6 records

Customer concentration

• LinkedInlinkedin.com/company/nucleusbiotech

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Nucleus Biotech Gmbh