Sordina IORT Technologies

What Sordina IORT Technologies does

S.I.T. – Sordina IORT Technologies S.p.A. is an Italian privately-held medical device company headquartered in Rome with manufacturing in Aprilia, Italy, that designs, manufactures, distributes, and services miniaturized mobile electron linear accelerators for Intra-Operative electron Radiation Therapy (IOeRT) and FLASH Radiation Therapy research and clinical systems. The company's product portfolio spans three generations of IOeRT linacs (NOVAC 11, LIAC, and the flagship LIAC HWL), complemented by the IORT ECHO Treatment Planning System, the ElectronFlash preclinical research platform, the Chc FlashPrime clinical FLASH device (CE certification in progress), and the in-development VHEE FLASH system for deep-seated tumors. Core technology centers on compact linear accelerator architecture combined with patented radiation protection that enables operation in standard operating rooms without additional shielding, supporting over 300 patients per year per system with treatment delivery under 2 minutes across up to 144 dosimetric field combinations.

The company operates an enterprise field-sales motion targeting hospitals and clinical radiotherapy centers, supplemented by an international distributor network and a congress-centric demand-generation strategy centered on major industry events (ESTRO, FRPT). Revenue is generated through capital equipment sales of high-value linac systems plus recurring after-sales service, technical support, and custom research configurations (e.g., customized ElectronFlash for ATOMKI). With 50+ systems installed globally and 30,000+ patients treated to date, S.I.T. is pursuing the clinical translation of FLASH radiotherapy through newly funded consortium R&D (LIAC FLASH GT under Italy's MIMIT program), a 6-year loan of the first clinical FLASH IORT device to Hospital Gregorio Marañón, and entry into new geographies (Spain, Hungary).

Name

Sordina IORT Technologies

Legal name

S.I.T. – Sordina IORT Technologies S.p.A.

Website

https://soiort.com

Company type

Private

Founded year

2012

Operating status

Operating

Headcount range

11–50 employees

Short description

S.I.T. – Sordina IORT Technologies designs, manufactures, and services miniaturized mobile electron linear accelerators for Intra-Operative electron Radiation Therapy and FLASH radiation therapy, selling IOeRT and FLASH systems to hospitals, cancer centers, and research institutions worldwide.

Ownership category

akta.pro rank

Product category

Radiotherapy Medical Devices

NAICS

Irradiation Apparatus Manufacturing (334517), Electromedical and Electrotherapeutic Apparatus Manufacturing (334510)

SIC

Electromedical & Electrotherapeutic Apparatus (3845), X-Ray Apparatus & Tubes & Related Irradiation Apparatus (3844)

akta.pro primary industry

Interventional Radiology & Image-Guided Therapy Systems (HLAHABAG)

akta.pro secondary industry

Radiation Protection & Health Physics (ALARA, Dosimetry, Contamination Control) (EUAKABAH)

Keywords

• Intraoperative radiation therapy
• Mobile electron accelerators
• FLASH radiation therapy
• Linear accelerator systems
• Radiotherapy medical devices

Headquarters

HQ city

Vicenza

HQ country

Italy

HQ region

Europe

Offices2 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Operations, Personnel, Technology or R&D, Marketing or Sales, Infrastructure

Revenue model

1. Medical Device Capital Equipment Sales: Sale of capital medical devices including LIAC HWL, NOVAC 11, ElectronFlash, and Chc FlashPrime linear accelerator systems to hospitals and clinical centers. Systems are sold with installation, commissioning, and initial training. Revenue is characterized by long sales cycles, high transaction values, and multinational distribution.
2. After-Sales Service and Technical Support: Ongoing after-sales service, maintenance, and technical support for installed systems. The company provides radioprotection planning, dosimetric characterization, training, and operational support. May include multi-year service agreements.
3. Research Collaboration and Custom Systems: Delivery of customized research accelerator systems (e.g., ElectronFlash for ATOMKI with electron and photon beam capabilities) and scientific collaboration agreements generating revenue from specialized research-grade equipment configurations.

Go-to-market motion2 records

Distribution channels2 records

Marketing channels6 records

Core offering

S.I.T. – Sordina IORT Technologies designs, manufactures, distributes, and provides after-sales service for miniaturized mobile electron linear accelerators used in Intraoperative electron Radiation Therapy (IOeRT) and FLASH Radiation Therapy. The portfolio spans clinical IOeRT systems (LIAC HWL, NOVAC 11, LIAC), the IORT ECHO Treatment Planning System, and FLASH platforms (ElectronFlash for research, Chc FlashPrime for clinical use, VHEE FLASH for deep-seated tumors), enabling precise single-dose radiation delivery directly to tumor beds during surgery in standard operating rooms.

Product overview

S.I.T. – Sordina IORT Technologies S.p.A. is the only Italian company and one of few in the world designing, manufacturing, distributing, and performing after-sales service of miniaturized mobile electron linear accelerators for Intra Operative electron Radiation Therapy (IOeRT) and FLASH Radiation Therapy research systems. The product portfolio centers on three generations of linear accelerators (LIAC, LIAC HWL, and NOVAC 11) for IOeRT procedures, complemented by the IORT ECHO TPS treatment planning system. The company is transitioning toward FLASH Radiotherapy with the ElectronFlash research platform, the Chc FlashPrime clinical device (CE certification in progress), and the VHEE FLASH system for deep-seated tumors.

Differentiator

Problem solved

Functional benefit

Brands

• LIAC HWL: Latest and most advanced model of SIT mobile electron linear accelerators for Intra Operative electron Radiation Therapy (IOeRT). Available in 10 MeV and 12 MeV models. Requires no additional shielding or structural modifications to operating rooms.
• LIAC
• NOVAC 11
• TPS (Treatment Planning System)
• ElectronFlash
• Chc FlashPrime
• VHEE

Products and services

• LIAC HWL Latest-generation mobile electron linear accelerator for Intraoperative electron Radiation Therapy (IOeRT). Available in 10 MeV and 12 MeV models, weighing 570 kg with energies 4–12 MeV. Capable of delivering IOeRT in under 2 minutes (less than 150 seconds), operates in standard operating rooms without additional shielding, supports workload of over 300 patients per year, and offers up to 144 different dosimetric field combinations. Commissioning achievable in 5 days using Monte Carlo simulation.
• IORT ECHO TPS (Treatment Planning System)

Quantifiable outcome

• 30,000+ oncological patients treated worldwide with LIAC HWL technology across multiple cancer types
• +5 more outcomes

Named customers4 records

Segments2 records

Ideal customer profiles2 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature6 records

Partnerships

Five partnerships are on record, tiered core and minor.

• Hospital General Universitario de ElchecoreStrategic or Co-development Partner · 1 March 2026Activation of the LIAC HWL system at Hospital General Universitario de Elche in Spain, where the first IORT procedure with the device was successfully performed on March 10, 2026. The partnership involves clinical collaboration with the hospital's radiobiologists, medical physicists, radiation oncologists, surgeons, and SIT representatives for procedure implementation.
• LIAC FLASH GT Research ConsortiumcoreStrategic or Co-development Partner · 1 March 2026SIT serves as the lead partner (capofila) in the LIAC FLASH GT project — a research and development initiative on FLASH IORT spatial fractionation medical devices — funded by Italy's Ministry of Enterprises and Made in Italy (MIMIT) under the 'Fondo per la Crescita Sostenibile – Accordi per l'Innovazione' program. The consortium includes Azienda Ospedaliera Universitaria Pisana (AOUP), Sapienza University of Rome (SBAI), and Fondazione Policlinico Agostino Gemelli IRCCS.
• ATOMKI – Institute for Nuclear ResearchcoreStrategic or Co-development Partner · 1 February 2026SIT signed a strategic agreement with ATOMKI, one of Europe's leading centers for nuclear physics and radiation studies, for the delivery of a customized ElectronFlash system with both electron and photon beam capabilities and fast mode switching. Technical acceptance testing was conducted at SIT's Aprilia facility in January 2026, followed by system installation at ATOMKI in March 2026, marking the start of structured scientific collaboration.
• Hospital General Universitario Gregorio Marañón (HGUGM)coreStrategic or Co-development Partner · 1 December 2025HGUGM was selected as the winner of the 'FLASH MD: Be the First' contest and will receive the world's first clinically certified FLASH IORT medical device on a 6-year loan-for-use basis. Under Professor Felipe A. Calvo's leadership, the center will contribute to the clinical translation of FLASH IOeRT, establishing practical conditions and methodological approaches for safe introduction of FLASH into clinical practice.
• Confindustria Dispositivi MediciminorOthers · 1 April 2025S.I.T. officially became a member of Confindustria Dispositivi Medici, the national association representing biomedical and medical device companies in Italy. Membership provides access to specialized training resources, dedicated consulting services, and a broad network of companies and professionals, facilitating knowledge exchange and collaborative innovation.

Scale indicators10 records

Recent moves6 records

Expansion highlights7 records

Direct peers

• IntraOp Medical: IntraOp Medical manufactures the Mobetron, a mobile electron linear accelerator for Intra-Operative Radiation Therapy (IORT), making it the most direct global competitor to S.I.T.'s LIAC HWL platform. Both companies target the same surgical oncology + radiation oncology clinical workflow with similar miniaturized mobile linac technology.
• GMV Innovating Solutions: GMV has developed and supported intraoperative radiation therapy systems in the European market, overlapping with S.I.T.'s IOeRT clinical offering. As a direct competitor in European IORT equipment, it shares the same target customer base of surgical-radiation oncology centers.

Broad incumbents

• Carl Zeiss Meditec: Carl Zeiss Meditec offers Intrabeam, a low-energy kV x-ray IORT system, addressing the same intraoperative radiation therapy clinical use case as S.I.T. but with a fundamentally different modality. As a much larger diversified ophthalmology and microsurgery player, it serves as a broad incumbent in the IORT space.
• Elekta: Elekta is one of the two dominant global radiation therapy equipment manufacturers, offering linacs (Versa HD, Elekta Unity MR-linac), brachytherapy, and treatment planning software that overlap with S.I.T.'s IOeRT/FLASH ecosystem. Its installed base and clinical relationships dwarf S.I.T.'s, representing both competitive threat and potential acquirer profile.
• Varian Medical Systems (Siemens Healthineers): Varian (now part of Siemens Healthineers) is the other dominant radiation oncology incumbent, with comprehensive linac, proton therapy, and treatment planning portfolios. Its FLASH research programs and global sales force make it the principal competitor S.I.T. would face in scaling clinical FLASH IORT.
• Accuray: Accuray develops the CyberKnife and TomoTherapy/Helical platforms for stereotactic and image-guided radiation therapy, competing for the same hospital radiation oncology capital budgets. Though its technology approach differs, it competes in the same procurement conversations as S.I.T. for advanced radiation therapy equipment.

Emerging players

• Brainlab: Brainlab offers Elements and ExacTrac radiation oncology treatment planning, image guidance, and surgical software that complement or compete with S.I.T.'s IORT ECHO TPS. As a focused but growing player in radiation oncology and surgical oncology software, it overlaps with S.I.T.'s planning and image-guidance capabilities.
• RefleXion Medical: RefleXion Medical develops the X1 biology-guided radiation therapy system, representing next-generation radiation therapy with real-time tumor tracking. It is a relevant emerging player in advanced radiation therapy that could compete for FLASH and advanced modality hospital investments.
• ViewRay: ViewRay pioneered MR-guided radiation therapy with the MRIdian system, addressing the image-guided advanced radiation therapy market adjacent to S.I.T.'s IORT/FLASH positioning. As an emerging modality player, it competes for innovative radiation oncology budgets at academic medical centers.
• RaySearch Laboratories: RaySearch Laboratories provides RayStation and RayCare treatment planning and oncology information systems used by major radiation therapy centers, with active research and partnerships in FLASH dose calculation. It is a relevant adjacent player for treatment planning workflows that complement or compete with S.I.T.'s IORT ECHO TPS.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks5 records

Key highlights7 records

Customer concentration

• Xx.com/SIT28281769
• LinkedInlinkedin.com/company/s-i-t-sordina-iort-tecnologies-s-p-a-

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Funding overview

Funding rounds1 record

Investors1 record

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Sordina IORT Technologies