IntraOp Medical

What IntraOp Medical does

IntraOp Medical Corporation, founded in 1993 and headquartered in Fremont, California, designs and manufactures the Mobetron, a portable, self-shielded electron-beam linear accelerator (LINAC) for intraoperative radiation therapy (IORT), FLASH radiotherapy, and non-invasive skin cancer treatment. The Mobetron's core technical differentiator is its miniaturized x-band architecture and integrated shielding, which allows deployment in standard operating rooms without the costly radiation bunker construction required by conventional LINACs. The system delivers electron energies of 6, 9, and 12 MeV with field sizes from 3 to 10 cm; the UHDR variant achieves dose rates exceeding 1,000 Gy/s for FLASH research applications. The company also sells a dermatology-focused variant (Mobetron SC) and a family of thin-walled applicators with variable bevel angles for anatomical conformality during IORT.

Name

IntraOp Medical

Legal name

IntraOp Medical Corporation

Website

https://intraop.com

Company type

Private

Founded year

1993

Operating status

Operating

Headcount range

11–50 employees

Short description

IntraOp Medical manufactures the Mobetron, a portable self-shielded electron linear accelerator for intraoperative radiation therapy (IORT), FLASH radiotherapy, and skin cancer treatment, selling capital equipment directly to leading cancer hospitals, academic medical centers, and dermatology clinics globally.

Ownership category

akta.pro rank

Product category

Radiotherapy Medical Devices

NAICS

Irradiation Apparatus Manufacturing (334517), Electromedical and Electrotherapeutic Apparatus Manufacturing (334510)

SIC

Surgical & Medical Instruments & Apparatus (3841), Electromedical & Electrotherapeutic Apparatus (3845)

akta.pro primary industry

Radiation Therapy Planning & Simulation Imaging (CT Sim/MR Sim) (HLAHABAH)

akta.pro secondary industries

Radiation Oncology (HLAKAFAC), Radiation Dose Management & Analytics (HLACALAH)

Keywords

• Intraoperative radiation therapy
• Electron linear accelerator
• Radiotherapy medical devices
• FLASH radiotherapy systems
• Mobile radiation therapy

Headquarters

HQ city

Sunnyvale

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Technology or R&D, Personnel, Operations, Marketing or Sales

Revenue model

1. Medical Device Capital Equipment Sales: Sale of Mobetron electron linear accelerator systems to hospitals, cancer centers, and academic medical institutions. The Mobetron is a capital equipment purchase requiring significant upfront investment. Revenue is one-time per unit sale with potential for service and support contracts.
2. Service and Support Contracts: Ongoing customer support and service contracts for installed Mobetron units. Provides recurring revenue stream from existing customer base.
3. FLASH Radiotherapy Research Platform: Mobetron UHDR system sold or licensed to research institutions for FLASH radiotherapy clinical trials and preclinical studies.

Pricing tiers

Go-to-market motion2 records

Distribution channels1 record

Marketing channels7 records

Core offering

IntraOp Medical designs, manufactures, and sells the Mobetron, a portable self-shielded electron-beam linear accelerator used to deliver intraoperative radiation therapy (IORT) directly to the tumor bed during cancer surgery. The system is offered in configurations for surgical IORT, ultra-high dose rate (UHDR) FLASH radiotherapy research and trials, and non-invasive dermatology treatment of non-melanoma skin cancer, supported by configurable treatment applicators and DICOM-compatible treatment planning software.

Product overview

IntraOp Medical offers a portfolio of electron therapy linear accelerator systems centered on the Mobetron platform. The core Mobetron is a mobile, self-shielded electron LINAC for intraoperative radiation therapy (IORT) during surgery. The Mobetron SC variant targets dermatology clinics for non-invasive skin cancer treatment. The Mobetron UHDR variant adds ultra-high dose rate (UHDR) FLASH radiotherapy capability for research and clinical trials. All systems share the same core electron-beam technology with configurable applicators and treatment planning software.

Differentiator

Problem solved

Functional benefit

Brands

• Mobetron: IntraOp's flagship product - the IntraOp Mobetron is a comprehensive electron therapy linear accelerator system with applications in intraoperative radiotherapy (IORT) and non-invasive treatment of skin cancer. It is the first mobile, self-shielded electron-beam LINAC for IORT.

Products and services

• Mobetron (Intraoperative Radiation Therapy System) The flagship mobile, self-shielded electron-beam linear accelerator (LINAC) system designed to deliver intraoperative radiation therapy (IORT) during cancer surgery. Features electron energies of 6, 9, and 12 MeV with applicators ranging from 3-10 cm field sizes. Enables radiation oncologists and surgeons to deliver high-dose radiation directly to the tumor bed during surgery without transporting patients to shielded radiation facilities. Indicated for breast, pancreatic, colorectal, gynecological, head and neck, and sarcoma cancers.
• Mobetron UHDR (FLASH Radiotherapy System) Ultra-high dose rate (UHDR) electron therapy capability for FLASH radiotherapy research and clinical trials. Delivers dose rates greater than 1,000 Gy/s with electron energies of 6 MeV and 9 MeV and field sizes up to 10 cm. The only FDA-approved mobile electron LINAC for FLASH clinical trials, supporting landmark studies such as the IMPulse Trial at CHUV Lausanne where FLASH RT was delivered safely up to 28 Gy in humans. Sold or licensed to research institutions for FLASH radiotherapy translational research.
• Mobetron SC (Skin Cancer Electron Therapy System) Compact, non-invasive electron therapy system specifically designed for dermatology clinics to treat non-melanoma skin cancer. Features integrated shielding, DICOM-compatible treatment planning software, and robotic movement with six degrees of freedom enabling deployment in standard dermatology clinic settings without special construction. Achieves 90-98% cure rates for non-melanoma skin cancer. Trademarked as Dermabeam.

Quantifiable outcome

• Treatment time reduced from 6 weeks to 2 minutes for breast cancer radiation
• +5 more outcomes

Named customers7 records

Segments6 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration1 record

Feature5 records

Partnerships

Four partnerships are on record, tiered core and minor.

• Lausanne University Hospital (CHUV)coreStrategic or Co-development Partner · 1 June 2021IntraOp collaborated with CHUV on the IMPulse Trial, the world's first human dose escalation study of single fraction FLASH radiotherapy for cutaneous melanoma metastases. CHUV treated 15 lesions in 11 patients between June 2021 and September 2024 using Mobetron UHDR. Two landmark peer-reviewed papers published in Radiotherapy & Oncology and JACMP demonstrating Mobetron's stability and clinical safety for FLASH applications.
• CHUV (Lausanne University Hospital)coreStrategic or Co-development PartnerLeading researchers from CHUV including Prof. Jean Bourhis (Chief of Radiation Oncology), Marie-Catherine Vozenin PhD (HDR), and Raphael Moeckli PhD collaborate with IntraOp on FLASH radiotherapy research. CHUV is the world's leading research institution for FLASH radiotherapy with published studies on FLASH effect, therapeutic potential, and clinical translation.
• Ohio State University James Cancer HospitalminorStrategic or Co-development PartnerDr. Arnab Chakravarti, Chair and Professor of Radiation Oncology at OSUCCC – James, partnered with IntraOp on FLASH radiotherapy investigations. Dr. Chakravarti stated: 'We are extremely excited to partner with IntraOp to launch key investigations paving the way for future clinical implementation of FLASH-electrons.'
• MD Anderson Cancer CenterminorStrategic or Co-development PartnerMD Anderson collaborated with CHUV on multi-institutional study demonstrating independent reproduction of the FLASH effect on the gastrointestinal tract using FLASH Mobetron systems. Both institutions demonstrated comparable FLASH-enabled animal survival and intestinal crypt regeneration.

Scale indicators7 records

Recent moves6 records

Expansion highlights6 records

Broad incumbents

• Elekta: Major radiation therapy equipment manufacturer with LINAC systems (Versa HD, Elekta Unity) and the Leksell Gamma Knife. Competes with IntraOp for capital budgets in radiation oncology departments globally.
• Varian (Siemens Healthineers): Global leader in radiation oncology hardware and software with the largest LINAC installed base. Varian offers broader external-beam radiotherapy systems (TrueBeam, Edge) and competes indirectly with Mobetron through comprehensive cancer center contracts.

Emerging players

• iCAD: Provider of radiation therapy solutions including the Xoft electronic brachytherapy system, which competes in the intraoperative and skin cancer radiation segments similar to Mobetron SC.
• Mevion Medical Systems: Manufacturer of compact proton therapy systems (MEVION S250i) that compete for advanced radiation oncology capital. Targets similar leading cancer centers but in the adjacent proton therapy modality.
• Accuray: Specialty radiation oncology company offering CyberKnife and TomoTherapy systems. Competes for advanced radiation therapy capital budgets and serves similar leading cancer center customers.
• RefleXion Medical: Developer of biology-guided radiotherapy (BgRT) using PET signals for cancer treatment. Targets similar advanced radiation oncology buyers and represents a potential technology disruption in the same customer accounts.
• ViewRay: Developer of the MRIdian MRI-guided radiation therapy system. Competes for advanced radiation oncology capital at leading cancer centers and serves similar clinical customer profiles.

Others

• Brainlab: Provider of radiotherapy hardware/software (ExacTrac) and surgical navigation systems used in oncology operating rooms. Overlaps with IntraOp's surgical oncology customer base and OR workflow integration.
• RaySearch Laboratories: Treatment planning software (RayStation, RayCare) provider for radiation therapy. Overlapping customer base with IntraOp in cancer centers; complementary rather than directly competitive as software vendor.

Direct peers

• Carl Zeiss Meditec (Intrabeam): Maker of the Intrabeam photon-based IORT system, the closest direct competitor to Mobetron. Uses 50 kV X-rays (vs. electrons) for IORT during breast cancer surgery, competing head-to-head for the same surgical oncology customers.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks7 records

Key highlights7 records

Customer concentration

• YouTubeyoutube.com/@Intraop
• Xx.com/intraop_medical
• LinkedInlinkedin.com/company/intraop

Compliance2 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles2 records

Funding overview

Funding rounds3 records

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about IntraOp Medical