FHIR Engine

What FHIR Engine does

FHIR Engine (FHIREngine Inc.) is a privately held U.S. healthcare IT company founded in 2021 and headquartered in Boston, MA, with a wholly-owned India subsidiary operating offices in Bengaluru, Hyderabad, Pune, and Mumbai. The company sells ONCOSure™, an oncology-specific clinical decision support (CDS) platform that helps hospitals, oncology providers, and EMR vendors create and personalize treatment plans based on guidelines from NCG, NCCN, AJCC, and ICMR. The platform is preconfigured with a SNOMED CT terminology server, integrated prior authorization capabilities, and AI-based analytics for biomarker recommendations, and integrates into EMR systems via SMART on FHIR.

The underlying technology stack is HL7-FHIR based, augmented with X12 EDI (278/275 for prior authorization and 270/271 for eligibility) and SNOMED CT terminology services, positioning the product for interoperability mandates including FHIR R4/R5 and TEFCA. Core go-to-market combines direct enterprise sales to hospitals, OEM/embedded distribution through EMR vendors using the SMART on FHIR app, and a channel partnership with Amoeba Business Solutions in India. Revenue is generated through platform licensing, subscription-based SMART on FHIR app distribution, and professional services for implementation.

The company has no disclosed funding beyond a single ~$792,915 round in March 2025, no public revenue, 1–10 employees, no disclosed management team, and no patents or formal awards. Customer logos are predominantly small and mid-market oncology providers and clinics (e.g., Lifepoint Hospital, Mauli Hospital, Cancer Center of Colorado, Geetai Hospital, Kotlwar Clinic, Pi Cancer Care), suggesting an early commercial stage with limited enterprise penetration.

Name

FHIR Engine

Legal name

FHIREngine Inc.

Website

https://fhirengineinc.com

Company type

Private

Founded year

2021

Operating status

Operating

Headcount range

1–10 employees

Short description

FHIREngine Inc. is a Boston-based healthcare IT company that sells ONCOSure, an oncology-specific clinical decision support platform integrating NCG, NCCN, AJCC, and ICMR guidelines with SNOMED CT and HL7-FHIR interoperability for hospitals, oncology providers, and EMR vendors.

Ownership category

akta.pro rank

Product category

Healthcare IT — Clinical Decision Support

NAICS

Computer Systems Design Services (541512), Computer Systems Design and Related Services (54151), Other Computer Related Services (541519)

SIC

Services-Prepackaged Software (7372), Services-Computer Programming, Data Processing, Etc. (7370)

akta.pro primary industry

Oncology Pathways & Precision Medicine Decision Support (HLACAGAH)

akta.pro secondary industries

Clinical Decision Support & Workflow Integration (EHR/oncology systems) (HLAAANAE), Interoperability Standards, Profiles & Implementation (HL7/FHIR/IHE) (HLACABAA), FHIR/HL7 Data Repositories & Canonical Data Models (HLACAIAI), Lab Data Exchange & Interoperability (HL7/FHIR/LDT Results Delivery) (HLACAMAL)

Keywords

• Clinical decision support
• Oncology treatment protocols
• Healthcare interoperability
• EMR integration
• Precision medicine

Headquarters

HQ city

Boston

HQ country

United States

HQ region

North America

Offices5 records

Markets served

GTM type

B2B

Offering type

Software

Cost components

Personnel, Technology or R&D, Operations, Marketing or Sales, Infrastructure

Revenue model

1. Healthcare IT Platform Licensing: Licensing of ONCOSure™ oncology clinical decision support platform to hospitals and EMR vendors. Platform includes SNOMED CT terminology server, oncology guidelines, AI analytics, and prior authorization modules.
2. SMART on FHIR App Distribution: Distribution of SMART on FHIR applications integrated into EMR systems, providing clinical decision support capabilities to healthcare providers.
3. Professional Services: Implementation and deployment services for healthcare organizations seeking to integrate FHIREngine products into their existing systems, helping payers and providers streamline operations.

Go-to-market motion3 records

Distribution channels3 records

Marketing channels4 records

Core offering

FHIR Engine develops ONCOSure™, an oncology-specific precision clinical decision support (CDS) platform that helps oncology providers and EMRs create and personalize treatment plans based on NCG, NCCN, AJCC, and ICMR guidelines. The platform is preconfigured with a full SNOMED CT terminology server, standard oncology guidelines, AI-based analytics, and an integrated prior authorization module, and is delivered via HL7-FHIR and SMART on FHIR standards for interoperability.

Product overview

FHIREngine Inc. is a US-based Healthcare IT company with a subsidiary in India that specializes in solutions for payers and providers. The company's portfolio centers on ONCOSure, an oncology-specific clinical decision support platform that integrates with EMR systems via SMART on FHIR. FHIREngine's products utilize HL7-FHIR, X12 EDI (278/275 and 270/271), and SNOMED CT-based architecture to help healthcare organizations streamline operations and reduce administrative burden. The ONCOSure platform targets both hospital systems (for automated clinical pathways and biomarker recommendations) and EMR vendors (for embedded decision support capabilities).

Differentiator

Problem solved

Functional benefit

Brands

• ONCOSure™: Oncology-specific precision clinical decision support (CDS) platform that helps oncology providers and EMRs create and personalize treatment plans based on guidelines recommended by NCG, NCCN, AJCC, ICMR. Comes preconfigured with SNOMED CT terminology server, standard oncology guidelines, advanced analytics, and integrated prior authorization module.

Products and services

• ONCOSure™

Quantifiable outcome

• Reduced treatment costs through evidence-based protocols and prior authorization automation
• +2 more outcomes

Named customers6 records

Segments3 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration1 record

AI capability2 records

Feature7 records

Partnerships

Five partnerships are on record, tiered core, flagship and minor.

• American Joint Committee on Cancer (AJCC)coreStrategic or Co-development PartnerAJCC is a clinical partner of FHIREngine, providing authoritative cancer staging guidelines that are integrated into the ONCOSure platform. The partnership enables evidence-based tumor classification using AJCC standards within the clinical decision support system.
• National Comprehensive Cancer Network (NCCN)coreStrategic or Co-development PartnerNCCN is a clinical partner providing biomarker guidelines and oncology treatment standards for the ONCOSure platform. The partnership ensures access to comprehensive cancer care standards and clinical practice guidelines embedded in the CDS system.
• American Medical Association (AMA)flagshipStrategic or Co-development PartnerAMA is a clinical partner providing medical standards and guidelines for oncology care integration. The partnership enhances credibility and ensures alignment with American medical standards for clinical decision support.
• Roch FoundationminorOthersRoch Foundation is listed as an associate partner, providing potential funding or strategic alignment with oncology research and treatment initiatives.
• Amoeba Business SolutionscoreChannel Partner/ Reseller/ DistributorAmoeba Business Solutions is a channel partner distributing FHIREngine products in the Indian market, particularly in India where FHIREngine has subsidiary offices in Bengaluru, Hyderabad, Pune, and Mumbai. The partnership expands market reach for ONCOSure in the Asia-Pacific region.

Scale indicators3 records

Recent moves5 records

Expansion highlights5 records

Direct peers

• Flatiron Health: Oncology-specific data and clinical decision support platform (acquired by Roche) serving hospitals, academic centers and life sciences companies. Closest direct competitor to ONCOSure in oncology-focused CDS, real-world evidence and EMR-embedded workflows.
• Tempus Labs: Precision medicine company combining genomic sequencing, clinical data and AI to support oncology treatment decisions. Competes with FHIR Engine on AI-driven oncology decision support, biomarker recommendations and integration into provider workflows.
• Syapse: Precision oncology platform used by health systems to support molecular tumor boards and evidence-based treatment selection. Direct overlap with ONCOSure's guideline-driven, biomarker-aware oncology CDS use case inside large provider networks.
• CancerIQ: Oncology risk-assessment and clinical decision support platform embedded in EHRs to manage hereditary cancer programs and precision treatment. Comparable as a specialty oncology CDS layer that lives inside provider EMR environments.
• Navigating Cancer: Oncology patient management and care-pathway platform for community oncology practices, including treatment plan management and symptom monitoring. Overlaps with ONCOSure on standardized oncology pathways and treatment-protocol decision support.
• NantHealth: Provider of evidence-based oncology clinical decision support (e.g., eviti) integrated with payer benefits and treatment regimens. Directly comparable to ONCOSure on payer-aligned, regimen-level oncology decision support and prior authorization workflows.

Emerging players

• Redox: FHIR-native healthcare integration platform that connects EHRs to digital health applications. Comparable as an enabler of SMART on FHIR app distribution and the EMR-embedded channel that ONCOSure also relies on for go-to-market.

Broad incumbents

• Epic Systems: Dominant U.S. EHR vendor with built-in oncology decision support (Beacon) and deep FHIR/SMART app ecosystem. The most powerful channel and competitive threat to ONCOSure's strategy of embedding oncology CDS into the EMR.
• Oracle Health (Cerner): Major U.S. EHR platform (formerly Cerner) with embedded clinical decision support and an active FHIR/ interoperability roadmap. A broad incumbent whose oncology CDS roadmap competes with niche vendors like FHIR Engine.
• Philips Oncology Solutions: Large medtech and oncology informatics portfolio (including radiation oncology and tumor board solutions) with provider- and payer-facing decision support. Comparable as a broader incumbent offering oncology clinical workflows and pathway tooling to hospitals.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat6 records

Key risks6 records

Key highlights6 records

Customer concentration

Revenue estimate

Valuation estimate

Number of profiles

Subsidiaries1 record

Funding overview

Funding rounds1 record

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about FHIR Engine