DePuy Synthes

Name

DePuy Synthes

Legal name

Medical Device Business Services, Inc.

Website

https://depuysynthes.com

Company type

Private

Founded year

1895

Operating status

Operating

Headcount range

5,001–10,000 employees

Ownership category

akta.pro rank

Product category

Orthopedic Medical Devices

NAICS

Surgical Appliance and Supplies Manufacturing (339113), Surgical and Medical Instrument Manufacturing (339112), Electromedical and Electrotherapeutic Apparatus Manufacturing (334510)

SIC

Orthopedic, Prosthetic & Surgical Appliances & Supplies (3842), Surgical & Medical Instruments & Apparatus (3841), Electromedical & Electrotherapeutic Apparatus (3845)

akta.pro primary industry

Orthopedic Joint Reconstruction Implants (Hip/Knee/Shoulder/Elbow/Ankle) (HLAHAEAA)

akta.pro secondary industries

Surgical Navigation, Robotics & Patient-Matched Instrumentation (Ortho/Spine) (HLAHAEAL), Surgical Robotics & Computer-Assisted Surgery Platforms (HLAHADAF), Orthopedic Trauma & Extremities Fixation (Plates/Screws/Nails/External Fixation) (HLAHAEAB), Spine Implants & Motion Preservation (Fusion/Disc/Interspinous) (HLAHAEAC), Open & Minimally Invasive Surgical Instruments (Handheld, Laparoscopic, MIS) (HLAHADAA), Orthopedic & Implantable Devices (Plates, Screws, TPLO, Prosthetics) (HLAMAFAE)

Keywords

• Orthopedic implants
• Joint reconstruction
• Surgical robotics
• Spine surgery devices
• Digital surgery platform

Headquarters

HQ city

Raynham

HQ country

United States

HQ region

North America

Offices3 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Technology or R&D, Marketing or Sales, Personnel, Operations

Revenue model

1. Hip and Knee Replacement Devices: Primary revenue stream from hip, knee and shoulder implants and surgical instruments for joint reconstruction procedures.
2. Spine Products: Spinal implant systems and surgical devices for spine procedures.
3. Enabling Tech / Digital Surgery: VELYS Digital Surgery platform including robotic systems, navigation software, and related disposables and services.
4. Trauma and Extremity Products: Products for foot and ankle, trauma, and extremities procedures including acquired CrossRoads Extremity Systems portfolio.

Go-to-market motion3 records

Distribution channels3 records

Marketing channels4 records

Core offering

DePuy Synthes manufactures and sells orthopedic medical devices and surgical equipment, including hip, knee, and shoulder implants, trauma and extremity products, spine implants, sports medicine devices, and craniomaxillofacial products. The company also offers the VELYS Digital Surgery portfolio of robotic-assisted and AI-enabled navigation systems for joint replacement procedures, sold to hospitals, surgical centers, and orthopedic surgeons worldwide.

Product overview

DePuy Synthes provides one of the most comprehensive Orthopaedics portfolios in the world spanning joint reconstruction (hip, knee, shoulder), trauma, craniomaxillofacial, spinal surgery, sports medicine, and extremities, along with the VELYS Digital Surgery portfolio of robotic and enabling technologies. The portfolio includes the ATTUNE Knee System, INHANCE Shoulder System, and TIGHT-N Anchor as core implant products; VELYS Hip Navigation with AI Assistance and VELYS Active Robotic-Assisted System as enabling technology modules; MatrixSTERNUM for thoracic procedures; and acquired brands including CrossRoads Extremity Systems for foot and ankle. The VELYS platform serves as the digital surgery ecosystem integrating robotics, navigation, and AI capabilities across the reconstruction portfolio.

Differentiator

Problem solved

Functional benefit

Brands

• VELYS: Digital Surgery portfolio including robotic surgery systems and surgical navigation technology for joint replacement procedures
• ATTUNE
• INHANCE
• TIGHT-N Anchor
• MatrixSTERNUM
• Gemtrack

Products and services

• VELYS Digital Surgery Platform Enabling technology portfolio of robotic surgery systems, surgical navigation software, and AI-assisted solutions for joint replacement procedures including hip, knee, and shoulder.
• ATTUNE Knee System A comprehensive, integrated primary knee replacement system designed to improve functional outcomes for patients, performance for surgeons, and efficiency for healthcare providers.
• TIGHT-N Anchor Next-generation tendon fixation device designed to protect tendons from wrap and laceration, featuring sub-cortical placement for high-strength fixation in sports medicine and ligament repair procedures.
• INHANCE Shoulder System Stemless shoulder replacement implant with ONE STEP PREP Glenoid designed to streamline shoulder arthroplasty procedures and address long-standing inefficiencies in shoulder surgery.
• VELYS Hip Navigation with AI Assistance FDA 510(k)-cleared software-as-a-medical-device (SaMD) for total hip arthroplasty that automates image interpretation and landmark identification using AI trained on over 16,000 de-identified X-ray and fluoroscopic images.
• MatrixSTERNUM Fixation System Plate and screw assembly for post-operative chest wall stabilization following open-heart and thoracic surgeries.
• VELYS Active Robotic-Assisted System FDA-cleared robotic-assisted surgery system for spinal fusion procedures developed in collaboration with eCential Robotics.
• CrossRoads Extremity Systems Portfolio Portfolio of elective foot and ankle products including minimally invasive surgical solutions for bunions and hammertoes.
• DePuy Synthes Skills Lab / Johnson & Johnson Institute Training Hands-on surgeon training programs and skills labs in joint replacement and robotic-assisted surgical techniques, delivered through facilities such as the DePuy Synthes Skills Lab in Pune and the Johnson & Johnson Institute.

Quantifiable outcome

• 57% reduction in workflow time for hip replacement surgeries (from 5.33 to 2.27 minutes for landmark identification)
• +1 more outcomes

Named customers2 records

Segments4 records

Ideal customer profiles2 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration1 record

AI capability5 records

Feature5 records

Partnerships

Five partnerships are on record, tiered minor and core.

• Saishree Vitalife HospitalsminorStrategic or Co-development Partner · 8 June 2026Partnership to launch the DePuy Synthes Skills Lab in Pune, India - a dedicated training facility for orthopaedic surgeons providing hands-on training in advanced joint replacement and robotic-assisted surgical techniques, with focus on surgeons from tier 2 and tier 3 cities.
• MinMaxMedicalcoreTechnology or Integration · 26 May 2026DePuy Synthes announced a definitive agreement to acquire selective rights to develop, manufacture, and commercialize Gemtrack miniature Radiofrequency tracking technology developed by MinMaxMedical (Grenoble-based). The technology eliminates line-of-sight dependency of current infrared optical tracking systems and will be integrated into the VELYS Digital Surgery platform for shoulder, hip, and knee procedures.
• CGBIOcoreChannel Partner/ Reseller/ Distributor · 26 May 2026Exclusive distribution agreement for NOVOSIS, an advanced growth-factor bone graft substitute, covering United States, Canada, and Australia. An IDE study for spine procedures is actively enrolling in the U.S. The agreement builds on a prior February 2025 distribution arrangement for Korea, Taiwan, Thailand, India, Hong Kong, and Macau, with rights of first negotiation for additional global markets.
• eCential RoboticscoreTechnology or Integration · 1 August 2024Partnership with eCential Robotics to enhance surgical navigation and robotic-assisted spine surgery capabilities. In August 2024, DePuy Synthes launched the FDA-cleared VELYS Active Robotic-Assisted System for spinal fusion surgeries developed with eCential Robotics.
• CrossRoads Extremity SystemscoreStrategic or Co-development Partner · 10 February 2022DePuy Synthes acquired CrossRoads Extremity Systems, a Tennessee-based foot and ankle devices manufacturer, to expand its portfolio of elective foot and ankle products including minimally invasive solutions for bunions and hammertoes. The acquisition marked the conclusion of HealthpointCapital's investment in the company.

Scale indicators10 records

Recent moves8 records

Expansion highlights6 records

Direct peers

• Stryker Corporation: Stryker is one of the largest global orthopaedics companies, with the Mako robotic surgery system directly competing with DePuy Synthes' VELYS platform. Stryker's portfolio spans joint reconstruction, trauma, spine, and surgical instruments, making it the closest comparable in scale and product breadth.
• Zimmer Biomet: Zimmer Biomet is a top global orthopaedics competitor offering hip, knee, shoulder implants and the ROSA robotic surgery platform that competes head-to-head with VELYS. Both companies serve hospitals and ambulatory surgery centers with similar joint reconstruction and trauma portfolios.
• Smith & Nephew: Smith & Nephew competes directly in orthopaedics reconstruction (hip/knee/shoulder), trauma, extremities and sports medicine - the same specialty mix as DePuy Synthes. Both serve hospitals and surgical centers with comparable implant lines and robotics initiatives.
• NuVasive: NuVasive (now part of Globus Medical) specializes in spine surgery and enabling technologies directly competing with DePuy Synthes' spine franchise. Comparable focus on minimally invasive spine procedures and surgical integration aligns it closely as a spine-focused peer.
• Globus Medical: Globus Medical is a major spine and orthopaedics company offering implants, enabling technology, and surgical robotics that overlaps with DePuy Synthes' spine and VELYS platforms. The 2023 NuVasive merger expanded Globus's scale to compete more directly across DePuy Synthes' portfolio.
• Wright Medical (Stryker Trauma & Extremities): Wright Medical's extremities and trauma portfolio (now integrated into Stryker post-2020 acquisition) competes directly with DePuy Synthes' trauma/extremities business and the acquired CrossRoads Extremity Systems line. Specialization in foot, ankle, and upper extremities makes it a focused peer in those sub-segments.
• Orthofix Medical: Orthofix specializes in spine, orthobiologics, and bone-growth stimulation products competing with DePuy Synthes' spine franchise and bone-graft offerings (e.g., NOVOSIS). Its narrower portfolio makes it a focused direct peer in spinal and trauma-adjacent categories.

Broad incumbents

• Medtronic: Medtronic is a dominant player in spine implants and surgical navigation/robotics (Mazor, StealthStation), overlapping with DePuy Synthes' spine and enabling-tech franchises. As a much larger diversified medtech incumbent, it competes with DePuy Synthes in select categories rather than across the full orthopaedic portfolio.
• B. Braun (Aesculap): B. Braun's Aesculap division offers orthopaedic implants, surgical instruments, and spinal products that overlap with DePuy Synthes' portfolio. As part of the broader B. Braun medtech conglomerate, it competes across multiple orthopaedic segments without specializing in DePuy Synthes' specific niches.

Emerging players

• ConforMIS: ConforMIS develops patient-specific knee replacement systems, intersecting with DePuy Synthes' ATTUNE Knee System in the joint reconstruction category. As a smaller player focused on personalized implants, it represents an emerging niche competitor in the knee segment.

Market position

Strengths4 records

Weaknesses5 records

Competitive moat7 records

Key risks6 records

Key highlights7 records

Customer concentration

• YouTubeyoutube.com/user/DePuyVideos
• LinkedInlinkedin.com/company/depuysynthesorthopaedics
• Xx.com/DePuySynthes
• Facebookfacebook.com/DePuySynthes

Revenue estimate

Valuation estimate

Number of profiles

Profiles4 records

Subsidiaries1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A8 records

Investments1 record

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about DePuy Synthes