Cenegenics

What Cenegenics does

Cenegenics is a physician-led performance health and age management company founded in 1997 and headquartered in Las Vegas, Nevada, operating as a division of BestLife Holdings. The company delivers a concierge longevity medicine platform that combines 600+ biomarkers (drawn via in-home phlebotomy covering 270+ markers), advanced in-center diagnostics such as DEXA, VO2 Max, CIMT, neurocognitive testing, brain EEG, and 3D musculoskeletal scanning, with ongoing physician-led personalization across nutrition, fitness, nutraceuticals, and metabolic and hormonal optimization. Add-on modules extend the diagnostic surface through AI-analyzed partners: Advanced CCTA via Cleerly, Whole-Body MRI via Prenuvo, and 22,000-gene analysis via New Amsterdam Genomics, alongside Therapeutic Plasma Exchange deployed under a 2026 partnership with MDLifespan and a genetics integration with 3X4 Genetics (Jul 2024).

The commercial model is a hybrid of one-time Performance Health Assessments and recurring Optimize-style memberships, with pricing tailored during a complimentary consultation and HSA/FSA-eligible components. Cenegenics monetizes a distributed consumer base of 50,000+ lifetime members through 27 centers (20 U.S. and 7 international across Greece, Colombia, Portugal, Mexico, Kenya, Brazil, plus Puerto Rico), 40+ affiliated physicians, and a mobile phlebotomy layer that meets members at home or office. Customer acquisition spans content marketing, paid search, social, and PR features in Vogue, CNBC, GQ, Men's Health, and Fox News.

The recent strategic agenda has centered on capability and channel expansion: a Jan 2026 MDLifespan Therapeutic Plasma Exchange partnership followed by serial TPE launches in Beverly Hills (Feb 2026) and Miami (Apr 2026); the Jun 2026 acquisition and integration of Mayo Clinic-trained Human Sync bringing a Chief Health Officer executive-health model; and continued build-out of a preferred-diagnostic partner ecosystem. The reported outcomes — 2.6 years average biological age reversal per year on program, 17.4% body fat reduction, 31 biomarkers moved into optimal range, and an average 7-year member tenure — describe a high-retention, high-ticket consumer health business operating in the longevity medicine category it pioneered.

Name

Cenegenics

Legal name

Cenegenics (division of BestLife Holdings)

Website

https://cenegenics.com

Company type

Private

Founded year

1997

Operating status

Operating

Headcount range

101–250 employees

Short description

Cenegenics is a physician-led concierge longevity medicine practice offering 600+-biarker performance health assessments, ongoing Optimize membership programs, and AI-analyzed specialty diagnostics across 27 centers in the U.S. and internationally for HNW adults seeking biological age reversal.

Ownership category

akta.pro rank

Headquarters

HQ city

Las Vegas

HQ country

United States

HQ region

North America

Offices26 records

Markets served

GTM type

B2C

Offering type

Services

Cost components

Personnel, Operations, Marketing or Sales, Technology or R&D, Infrastructure

Revenue model

1. Membership-Based Performance Health Program: Ongoing membership program providing comprehensive testing, physician-led consultations, personalized nutrition, fitness training, nutraceuticals, metabolic and hormonal optimization, and quarterly biomarker monitoring. Performance Health Assessment priced separately from ongoing membership.
2. Performance Health Assessment: One-time comprehensive diagnostic evaluation including concierge phlebotomy, DEXA scan, VO2 Max, CIMT, neurocognitive testing, and physician consultation. Core entry point for new members.
3. Diagnostic Add-On Services: Optional advanced diagnostics including Whole-Body MRI (Prenuvo), Advanced CCTA (Cleerly), Advanced Genomics (New Amsterdam Genomics), and additional lab testing for deeper clinical insight
4. Nutraceutical Products: Pharmaceutical-grade supplementation recommendations and products tailored to individual deficiency profiles, delivered monthly as part of ongoing program

Pricing tiers

Go-to-market motion2 records

Distribution channels3 records

Marketing channels10 records

Core offering

Cenegenics delivers a physician-led performance health and age management program built around comprehensive biomarker analysis (600+ metrics), in-center advanced diagnostics (DEXA, VO2 Max, CIMT, neurocognitive testing, brain EEG, 3D musculoskeletal scanning), and ongoing personalized intervention plans covering nutrition, fitness, nutraceuticals, and hormone optimization. The offering is structured as an annual membership with a one-time Performance Health Assessment as the diagnostic entry point, supplemented by optional add-on diagnostics and at-home concierge phlebotomy.

Product overview

Cenegenics offers a unified performance health platform built around its core Optimize program and Performance Health Assessment. The Optimize program is the primary membership offering combining comprehensive biomarker testing (600+ metrics), in-center performance diagnostics (DEXA, VO2 Max, CIMT, neurocognitive testing), and ongoing physician-led coaching. The Performance Health Assessment serves as the diagnostic entry point establishing health baselines. Optional add-on tiers provide deeper clinical insight: Diagnostic Add-Ons include Advanced CCTA (AI-analyzed by Cleerly) and Whole-Body MRI (via Prenuvo); Lab Add-Ons include Advanced Genomics (via New Amsterdam Genomics), Micronutrient/Food Sensitivity Testing, and Therapeutic Plasma Exchange (via MDLifespan partnership). The portfolio is architecturally a platform-plus-modules model where the core program is required and add-ons extend into specialized diagnostics.

Differentiator

Problem solved

Functional benefit

Products and services

• Optimize Performance Health Program The flagship annual performance health membership program combining 600+ biomarker analysis, advanced performance diagnostics, and physician-led personalized intervention including nutrition, fitness training, nutraceuticals, and metabolic/hormonal optimization. Includes concierge phlebotomy at home/office and quarterly biomarker monitoring for adults seeking to optimize healthspan.
• Performance Health Assessment Comprehensive one-time diagnostic starting point including concierge phlebotomy (270+ biomarkers), health history assessment, physician consultation, DEXA scan, VO2 Max, carotid ultrasound (CIMT), neurocognitive testing, biological age calculation (TallyAge and PhenoAge), and Cenegenics Health Score.
• Advanced CCTA (Coronary CT Angiography) Diagnostic imaging evaluation analyzed by Cleerly AI platform for detailed analysis of plaque composition and cardiovascular risk beyond standard imaging.
• Whole-Body MRI Fast, non-invasive full-body scan by Prenuvo for early detection of cancer, aneurysms, and other diseases before symptoms appear.
• Advanced Genomics Analysis of all 22,000 genes using New Amsterdam Genomics validated AI platform to surface genetic risk factors, medication sensitivities, and variants with bearing on healthspan.
• Micronutrient and Food Sensitivity Testing Lab add-on testing cellular levels of vitamins, minerals, and antioxidants, and identifying immunologic response to various foods.
• Therapeutic Plasma Exchange Advanced Serial Therapeutic Plasma Exchange protocols using MDLifespan's PlasmaXchange technology. Multi-session physician-supervised plasma exchange combined with environmental toxin diagnostics and biomarker tracking.
• 3D Musculoskeletal (MSK) Scan 3D analysis of over 1 million data points mapping the body's musculoskeletal structure, movement patterns, and injury risk zones. Available at select centers.
• Brain EEG Measure of brain's physiological electrical response used to assess neurological performance and evoked potential in real time. Available at select centers.

Quantifiable outcome

• Members reverse biological age by average 2.6 years per year on program
• +7 more outcomes

Named customers7 records

Segments3 records

Ideal customer profiles3 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration4 records

AI capability3 records

Feature4 records

Partnerships

Eleven partnerships are on record, tiered core and preferred.

• Human SynccoreStrategic or Co-development Partner · 26 June 2026Mayo Clinic-trained clinical team integrated into Cenegenics, bringing Chief Health Officer model for executive health and longevity. Human Sync Founder Brad Pierce and co-founder Erik Nelson join Cenegenics clinical leadership. Both organizations built on continuous expert-led relationships.
• MDLifespancoreStrategic or Co-development Partner · 22 January 2026MDLifespan, a physician-led medical technology company and certified Public Benefit Corporation, partnered with Cenegenics to expand Therapeutic Plasma Exchange (TPE) across U.S. centers. MDLifespan provides its patented PlasmaXchange protocols; Cenegenics provides clinical facilities and physician oversight. Initial locations include Beverly Hills, Miami, and Atlanta. MDLifespan claims PlasmaXchange outperforms standard TPE by more than 300%.
• 3X4 GeneticscoreTechnology or Integration · 19 July 2024Partnership integrates 3X4 Genetics testing into Cenegenics health assessment and wellness programs. Clients receive a Blueprint Report identifying unique genetic pathways, enabling clinicians to fine-tune care plans tailored to each client's genetic profile. Aims to advance integration of genetics into clinical practice.
• PrenuvopreferredTechnology or IntegrationDiagnostic partner for Whole-Body MRI offering fast, non-invasive full-body scan for early detection of cancer, aneurysms, and other diseases. Award-winning technology from Prenuvo.
• CleerlypreferredTechnology or IntegrationDiagnostic partner for Advanced Coronary CT Angiography (CCTA) analyzed by Cleerly's clinically validated AI platform. Shows plaque composition and cardiovascular risk at detail standard imaging cannot achieve.
• New Amsterdam GenomicspreferredTechnology or IntegrationDiagnostic partner for Advanced Genomics analyzing all 22,000 genes using validated AI platform. Surfaces genetic risk factors, medication sensitivities, and variants with bearing on healthspan.
• Tru-DiagnosticpreferredTechnology or IntegrationDiagnostic partner for epigenetic testing and biological age assessment.
• GlycanAgepreferredTechnology or IntegrationDiagnostic partner for glycan-based age assessment.
• Spectra Cell LaboratoriespreferredTechnology or IntegrationLaboratory partner for specialized nutritional and cellular testing.
• Quest DiagnosticspreferredTechnology or IntegrationLaboratory partner for comprehensive biomarker testing.
• GE HealthcarepreferredTechnology or IntegrationHealthcare technology partner for diagnostic imaging and clinical equipment.

Scale indicators13 records

Recent moves6 records

Expansion highlights6 records

Direct peers

• Function Health: Membership-based direct-to-consumer platform offering 100+ lab biomarkers and personalized health insights. Direct competitor to Cenegenics in the premium preventive diagnostics and longevity category, though typically at a lower price point and digital-first delivery model.
• InsideTracker: Pioneer in personal biomarker analysis and longevity insights, combining blood testing with proprietary algorithms. Comparable to Cenegenics in biomarker-centric optimization and target customer of health-conscious adults, but delivered primarily through partnerships and digital channels rather than physician-led centers.
• Fountain Life: Premium longevity-focused health network offering advanced diagnostics, AI imaging, and personalized healthspan programs at flagship centers. Closely comparable to Cenegenics in concierge longevity positioning, physician-led model, and use of whole-body MRI and advanced cardiac imaging.
• Human Longevity Inc. Founded by Craig Venter, HLI offers comprehensive genomic, imaging, and clinical assessments focused on healthspan and preventive health. Direct peer in the premium longevity diagnostics space with similar biomarker-and-imaging-led value proposition aimed at HNW individuals.
• Next Health: Multi-location longevity and wellness optimization clinics offering IV therapy, hormone optimization, advanced diagnostics, and aesthetic services. Closely comparable to Cenegenics in the concierge longevity clinic format, member-based pricing, and physician-supervised protocols.

Emerging players

• Modern Age: Smaller-scale longevity clinic focused on skin, hair, hormones, and wellness with a digital front door. Comparable in the longevity optimization niche but with narrower scope, fewer diagnostics, and lower price point than Cenegenics.
• Hone Health: Direct-to-consumer hormone optimization and longevity platform with telemedicine-led delivery. Overlaps with Cenegenics on hormone therapy and biomarker-driven care for men over 35, but delivers care remotely rather than through physical centers.
• Prenuvo: Whole-body MRI screening service for early cancer and disease detection, offered both standalone and as a Cenegenics preferred diagnostic partner. Partially overlapping in longevity screening customer base but narrower in scope (imaging only).

Broad incumbents

• Thorne: Large-scale nutritional supplement brand with growing health testing and personalization capabilities. Comparable to Cenegenics in nutraceutical product sales and biomarker-guided supplementation, but operates at much broader scale and lower price points.

Others

• Quest Diagnostics: Large diagnostic laboratory services company and one of Cenegenics' preferred lab partners for comprehensive biomarker testing. Adjacent ecosystem participant rather than a competitor, providing infrastructure that enables Cenegenics' testing model.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key highlights8 records

Customer concentration

• Xx.com/cenegenics

Revenue estimate

Valuation estimate

Number of profiles

Profiles5 records

Funding overview

Funding rounds1 record

Investors4 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A1 record

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Cenegenics