What American Liver Foundation does

The American Liver Foundation is a U.S. nonprofit health organization founded in 1976 and headquartered in New York that works to advance liver disease prevention, treatment, and cure through education, patient support, research funding, and public policy advocacy. It serves the more than 100 million Americans affected by liver disease — including patients with MASLD/MASH, hepatitis, autoimmune liver diseases, pediatric liver disease, rare liver diseases, and liver cancer — alongside caregivers, healthcare professionals, and, through a dedicated U.S. Department of Veterans Affairs partnership, military veterans. Programs center on a portfolio of branded initiatives: the Think Liver Think Life national public health campaign, the Living Donor Network (launched 2025 as the first non-directed liver donor database in the U.S.), the Patient Registry, Bili the Brave pediatric program, Online Support Groups, Caring Connections peer mentoring, and a toll-free helpline (1-800-465-4837).

Its core infrastructure is a content and community platform rather than a unified software product: a multilingual website covering all liver diseases, event-driven programs (Liver Life Walk, Liver Life Challenge endurance events, FLAVORS culinary gala, National Legacy Gala, Irwin M. Arias biomedical symposium), and policy advocacy channels including the Liver Life Advocacy Summit in Washington, D.C. Notable technical components include the Living Donor Network transplant-matching database, the at-home LiverTrace cancer screening test offered via partner Helio Genomics, and the Veterans Information Center portal built with the VA and VHA. Cumulative research funding since 1979 is close to $30 million, with a record $1.1 million disbursed under previous board leadership.

ALF operates a philanthropic revenue model with no priced products: income is generated from individual donations (including the Liver of Life Society monthly giving program), event-driven fundraising, Corporate Council memberships, legacy/cryptocurrency giving, and event sponsorships. All educational content, support services, and clinical trial referral tools are provided free of charge to patients and caregivers. The organization carries Charity Navigator Four-Star and Charity Watch Top Rated designations and is currently commemorating its 50th anniversary under newly elected board chair David Frank.

Name

American Liver Foundation

Legal name

American Liver Foundation

Website

https://liverfoundation.org

Company type

Private

Founded year

1976

Operating status

Operating

Headcount range

251–500 employees

Short description

The American Liver Foundation, founded in 1976, is a U.S. nonprofit that delivers education, patient support, research funding, and policy advocacy for the 100 million Americans affected by liver disease, operating programs such as the Living Donor Network, the Veterans Information Center with the VA, and signature fundraising events.

Ownership category

akta.pro rank

Product category

Nonprofit Liver Disease Health Advocacy

NAICS

Voluntary Health Organizations (813212)

akta.pro primary industry

Hepatology & Liver Disease (HLAKAEAB)

akta.pro secondary industries

Transplant Hepatology (HLAKAEAK), Hepatology (Viral Hepatitis) (HLAKAGAC), Blood, Organ & Tissue Donation Organizations (BPAGACAJ), Liver & GI Clinical Research (Trials Centers) (HLAKAEAL)

Keywords

• Liver disease research
• Patient support services
• Health advocacy
• Medical education
• Living donor network

Headquarters

HQ city

New York

HQ country

United States

HQ region

North America

Offices4 records

Markets served

GTM type

B2C

Offering type

Services

Cost components

Personnel, Operations, Marketing or Sales, Technology or R&D, Others

Revenue model

1. Individual Donations: Direct donations from individuals supporting liver disease awareness, research, education, and patient support services. The organization promotes monthly donor campaigns (Liver of Life Society), one-time donations, and tribute gifts.
2. Event Fundraising: Revenue generated through signature events including FLAVORS culinary event, Liver Life Walk, Liver Life Challenge endurance events (Boston Marathon, Chicago Marathon), and National Legacy Gala.
3. Corporate Partnerships and Sponsorships: Corporate sponsorships through Corporate Council membership, clinical trial promotion partnerships, and event sponsorship opportunities including National Legacy Gala sponsorship.
4. Legacy Giving: Planned giving programs including leave a legacy bequests, Donor Advised Funds, and cryptocurrency donations.

Go-to-market motion2 records

Distribution channels5 records

Marketing channels8 records

Core offering

The American Liver Foundation is a national nonprofit health organization that provides liver disease education, patient and caregiver support, advocacy for federal funding and policy, and funded research for the prevention, treatment, and cure of liver disease. It delivers public-health campaigns (Think Liver Think Life), the Living Donor Network donor database, Bili the Brave pediatric program, peer-support communities, and signature fundraising events (FLAVORS, Liver Life Walk, Liver Life Challenge, National Legacy Gala, Liver Life Advocacy Summit) free of charge to patients, caregivers, and the public.

Product overview

American Liver Foundation operates as a nonprofit health organization offering a portfolio of patient education programs, support services, advocacy initiatives, and public health campaigns rather than a unified technology product. The core offerings include the Think Liver Think Life national public health campaign, the Living Donor Network (first non-directed liver donor database in the U.S.), and Bili the Brave pediatric program. The organization runs signature events including Liver Life Walk, Liver Life Challenge endurance program, FLAVORS culinary event, National Legacy Gala, and Liver Life Advocacy Summit. Patient resources include a Clinical Trials Finder tool, Veterans Information Center, Patient Registry, Online Support Groups, and Caring Connections peer support program. The organization also offers a helpline (1-800-465-4837), educational materials across multiple languages, and hosts the annual Irwin M. Arias Symposium for medical professionals. Through partnerships, ALF provides services like the LiverTrace at-home liver cancer test via Helio Genomics.

Differentiator

Problem solved

Functional benefit

Brands

• Think Liver Think Life: A national public health campaign which aims to ensure every American understands their risk for liver disease, receives the appropriate screening and care coordination and feels well-informed and supported throughout their liver journey.
• Living Donor Network
• Bili the Brave
• FLAVORS
• Liver Life Walk
• Liver Life Challenge

Products and services

• Think Liver Think Life National public health campaign ensuring Americans understand liver disease risk, screening, and care coordination, targeted at the general U.S. population.
• Living Donor Network First non-directed liver donor database in the United States, connecting individuals who wish to donate part of their liver with transplant centers nationwide to help children and adults in need; launched in 2025 and supporting nearly 9,000 Americans awaiting liver transplants.
• Bili the Brave A program for children and families affected by biliary atresia, including an animated video and toolkit that provides emotional support and education for young patients facing liver disease.
• Liver Life Walk Signature community walk fundraising event bringing together people affected by liver disease to raise awareness and funds.
• Liver Life Challenge Official endurance fundraising program in which dedicated athletes across the country use marathons and other athletic events to raise funds for the liver community.
• FLAVORS National culinary fundraising event featuring local top chefs preparing multi-course dinners tableside for guests in support of liver disease programs.
• National Legacy Gala Annual event held in New York City honoring individuals and families who have made significant contributions to liver health and celebrating achievements in medical innovation, research, and philanthropy.
• Liver Life Advocacy Summit Annual advocacy event in Washington, D.C., bringing together patients, caregivers, and families to advocate for liver health policies and increased federal investment in liver disease.
• Clinical Trials Finder Online resource helping liver disease patients find and enroll in clinical trials, including trials for MASH/NASH and Hepatocellular Carcinoma.
• Veterans Information Center Dedicated information center providing resources on early detection, lifestyle management, and educational materials addressing liver health issues for U.S. Veterans, developed in partnership with the U.S. Department of Veterans Affairs and VHA.
• Patient Registry Patient registry allowing individuals with liver disease to register and contribute their health information to support liver disease research and clinical trial participation.
• Online Support Groups Online peer support communities such as Sharing the Journey connecting liver disease patients and caregivers for shared experiences and mutual support.
• Caring Connections Peer Support Program Peer-to-peer support program connecting liver disease patients and families with trained volunteer mentors who have lived experience with liver disease.
• Liver of Life Society Monthly recurring donor program for supporters of the American Liver Foundation's mission, established as part of the organization's 50th anniversary.
• Helpline (1-800-465-4837) Toll-free helpline providing information, support, and resources for patients, caregivers, and families affected by liver disease.
• 34th Annual Irwin M. Arias Symposium Annual biomedical symposium in Fairfield, NJ bringing together scientists and physicians globally to discuss advances in liver disease research.
• LiverTrace Test At-home liver cancer test offered through partnership with Helio Genomics, providing early-detection results within 10–14 days for individuals at risk of liver cancer.

Quantifiable outcome

• 6.2 million patients, caregivers, and healthcare professionals benefit annually from ALF education, resources and support services
• +2 more outcomes

Named customers1 record

Segments4 records

Ideal customer profiles3 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature3 records

Partnerships

Six partnerships are on record, tiered flagship, core and minor.

• Boston Athletic AssociationflagshipGTM or Marketing Partner · 17 April 2026ALF participated as the Boston Athletic Association's first official charity team in the 130th Boston Marathon on April 20, 2026. The team aims to raise awareness and funds for ALF programs including living donor initiatives, pediatric liver disease support, and federal advocacy efforts.
• Helio GenomicsflagshipTechnology or Integration · 8 December 2025ALF partnered with Helio Genomics to provide at-home liver cancer testing and awareness in the United States. This initiative includes the LiverTrace test, which offers early detection results within 10 to 14 days, targeting individuals at risk of liver cancer.
• U.S. Department of Veterans Affairs (VA) and Veteran Health Administration (VHA)coreStrategic or Co-development Partner · 11 November 2025ALF launched a Veterans Information Center in partnership with the VA and VHA to support Veterans at risk of liver disease. The center provides resources on early detection, lifestyle management, and educational videos addressing liver health issues, targeting Veterans' specific needs.
• Bank of America Chicago MarathoncoreGTM or Marketing Partner · 10 October 2025ALF's Liver Life Challenge was an official charity partner of the 2025 Bank of America Chicago Marathon. The event took place on October 12, 2025, with ALF's fundraising team exceeding their goal through participation from various runners connected to liver disease.
• James Beard Award-winning Chef Christopher GrossminorGTM or Marketing PartnerFeatured celebrity chef at FLAVORS 2026 national culinary fundraising event in Phoenix, Arizona, adding prestige and media attention to the signature fundraising event.
• Bakari SellersminorGTM or Marketing PartnerNarrated the animated Bili the Brave video bringing the children's book to life, helping raise awareness for children affected by biliary atresia.

Scale indicators6 records

Recent moves6 records

Expansion highlights6 records

Broad incumbents

• American Cancer Society: National nonprofit raising funds for research, patient support, and advocacy around a single major disease category. ALF operates an analogous model at smaller scale for liver disease, making ACS the closest structural template for ALF's revenue mix, event programming, and federal advocacy strategy.
• American Heart Association: Large cardiovascular-focused nonprofit combining research funding, public health campaigns, patient education, signature events, and advocacy. AHA's mass-participation endurance events and national public awareness campaigns closely mirror ALF's Boston Marathon, Liver Life Walk, and Think Liver Think Life playbook.
• American Gastroenterological Association: Professional medical society for gastroenterology including hepatology, with overlapping CME, clinical guidelines, and research dissemination activities that complement (and partly overlap with) ALF's professional education and Irwin M. Arias Symposium programming.

Direct peers

• American Lung Association: Single-organ-disease national nonprofit delivering patient education, research grants, advocacy, and signature fundraising events (e.g., Lung Force Walk, Fight For Air Climb). Operates as a near-perfect structural parallel to ALF in mission, programs, and donor base.
• National Kidney Foundation: Kidney disease nonprofit providing patient education, peer support, research funding, and advocacy, with deep involvement in transplant-related programs (NKF Peers, transplant living donor support). Directly comparable to ALF on transplant and living donor programming given the structural similarity between kidney and liver transplantation.
• American Diabetes Association: National nonprofit addressing diabetes and related metabolic conditions, including the increasingly overlapping MASLD/MASH population that ALF serves. ADA's footprint in metabolic disease positioning, research grants, and patient education provides a useful comparison for how ALF could expand into metabolic-liver crossover audiences.
• Hepatitis B Foundation: National nonprofit dedicated to hepatitis B education, research, and patient advocacy. Directly competes with ALF on viral hepatitis patient education, clinical trial promotion, and federal advocacy, and serves an overlapping donor and patient population.
• Alpha-1 Foundation: Disease-specific nonprofit focused on Alpha-1 Antitrypsin Deficiency, which can manifest as serious liver disease. Operates a similar model of patient registry, research funding, peer support, and advocacy, and overlaps with ALF's pediatric and rare liver disease programming.

Others

• United Network for Organ Sharing (UNOS): Nonprofit that operates the U.S. organ allocation system under federal contract, including deceased-donor liver matching. UNOS is a critical infrastructure peer for ALF's Living Donor Network: both are liver-focused nonprofit entities shaping transplant logistics, with ALF filling the non-directed living donor gap UNOS does not address.

Emerging players

• PBC Foundation: UK-based patient organization dedicated to Primary Biliary Cholangitis, offering peer support, research funding, and disease education. Operates a smaller, condition-specific version of the same nonprofit playbook ALF uses, and could become a partnership model for ALF to internationalize rare liver disease programming.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat4 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/liverusa
• YouTubeyoutube.com/user/americanliver
• Facebookfacebook.com/liverinfo
• LinkedInlinkedin.com/company/american-liver-foundation
• Instagraminstagram.com/americanliver

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Funding overview

Funding rounds1 record

Investors1 record

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M&A

Investments

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Frequently asked questions about American Liver Foundation