Reaction
- Company typePrivate
- Founded2020
- HeadquartersPalo Alto, United States
- Headcount251–500
- GTM typeB2B
- OfferingServices
Reaction firmographics
Firmographics- Name
- Reaction
- Legal name
- Reaction
- Website
- https://reaction.global
- Company type
- Private
- Founded year
- 2020
- Operating status
- Operating
- Headcount range
- 251–500 employees
- Ownership category
- akta.pro rank
Reaction industry classification
Industry- Product category
- Venture Capital / Impact Investing
- NAICS
- Investment Banking and Securities Intermediation (523150), Portfolio Management and Investment Advice (52394)
- SIC
- Investment Advice (6282)
- akta.pro primary industry
- Impact / ESG Venture Capital (FSANAAAG)
- akta.pro secondary industries
- Climate / Clean Tech & Decarbonization Funds (FSANAJAA), Renewables & Energy Transition Funds (Solar, Wind, Hydrogen, CCUS) (FSANAEAD)
Keywords
Where Reaction is headquartered
LocationHeadquarters
- HQ city
- Palo Alto
- HQ country
- United States
- HQ region
- North America
Offices3 records
Markets served
Reaction business model
Business model- GTM type
- B2B
- Offering type
- Services
- Cost components
- Personnel, Operations, Marketing or Sales, Technology or R&D
Revenue model
- Venture Capital Returns: Reaction generates returns through equity investments in portfolio companies. The fund takes ownership stakes in startups and exits through various liquidity events. Returns are generated alongside creating positive social and environmental impact.
Go-to-market motion2 records
Distribution channels3 records
Marketing channels7 records
Reaction product offering
Product offeringCore offering
Reaction is a venture capital firm that operates two investment funds—W250 Venture (Fund I) and the Climate Innovations Catalyst Fund (Fund II)—providing capital, global network access, and operational support to early-stage and growth-stage startups. The firm sources deals primarily through a community of more than 200 Stanford GSB alumni partners across 50 countries, targeting ventures in health technology, climate innovation, enterprise technology, and education technology that align with its mission to measurably improve one billion lives within a decade.
Product overview
Reaction is a global venture capital firm operating two investment funds: W250 Venture (Fund I) and Climate Innovations/Catalyst Fund (Fund II). The W250 Fund invests in proven leaders across health technology and climate innovation sectors, while the Catalyst Fund specifically scales Stanford climate innovations globally. Reaction's portfolio spans climate technology (Antora Energy, Nitricity, 3Degrees, Mango Materials, GALY, Novoloop, Starship, Splight, FutureProof), enterprise and consumer technology (AiFi, JIFFY.ai, Jumbotail), health technology (Earli, Forta Health, Health Rhythms, Genetesis, Apollo Neuro, Zenysis), and education technology (Shoelace, Trybe, Galena). The organization provides capital, strategic guidance, and global network access to scale innovations worldwide.
Differentiator
Problem solved
Functional benefit
Brands
- W250 Venture: Fund I - The first fund of Reaction, named after the Stanford room where the organization began. Invests in proven leaders with world-changing potential, focusing on sectors such as health technology and climate innovation.
- Catalyst Fund for Climate Innovation
Products and services
- W250 Venture (Fund I) Reaction's first venture capital fund focused on investing in proven leaders and scaling their innovations globally across health technology and climate innovation sectors.
- Climate Innovations Catalyst Fund (Fund II) Climate-focused venture capital fund that scales Stanford-affiliated climate innovations globally, targeting Seed to Series B ventures in energy storage, renewable integration, sustainable materials, and carbon management.
Quantifiable outcome
- Over $3 Billion in enterprise value created by Managing Partner Dan Matthies over 15 years
- +4 more outcomes
Companies that use Reaction
Customer profileNamed customers21 records
Segments5 records
Ideal customer profiles3 records
Reaction technology and API
TechnologyTechnology focussed No
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
AI capability16 records
Reaction partnerships and signals
Strategic signalPartnerships
One partnership is on record.
- Stanford University / Distinguished Careers InstitutecoreFounders are Stanford alumni; fund leverages Stanford's leadership in climate tech and AI to identify transformative ventures. Multiple partners are Stanford DCI alumni.
Scale indicators8 records
Recent moves6 records
Expansion highlights6 records
Reaction competitors and assessment
Company assessmentDirect peers
- DBL Partners: Impact-focused venture capital firm co-founded by Reaction GP Mike Dorsey. DBL pioneered the double-bottom-line approach Reaction emulates, with a portfolio spanning climate, health, and sustainability — the most direct precedent and operational analogue.
- Obvious Ventures: Mission-driven venture firm investing in world-positive companies across health, climate, and economic empowerment. Comparable impact mandate, multi-thematic approach, and similar brand-led positioning to Reaction.
- Breakthrough Energy Ventures: Bill Gates-backed climate tech venture fund deploying over $1B into companies working on net-zero solutions. Directly comparable to Reaction's Catalyst Fund in thematic focus, stage, and the 'patient capital' approach.
- DCVC (Data Collective): Deep-tech venture firm investing in computational and climate technologies such as grid optimization and biotech. Comparable to Reaction's AI-for-climate thesis and willingness to back science-heavy founders.
- Prime Movers Lab: Early-stage deep-tech fund backing breakthroughs in energy, transportation, infrastructure, and human health. Comparable to Reaction's Catalyst Fund on stage, thesis, and science-driven sourcing.
- Clean Energy Ventures: Seed-stage climate tech fund investing across energy, mobility, buildings, and carbon. Direct peer to Reaction's Catalyst Fund given shared focus on early-stage climate innovation.
- Congruent Ventures: Early-stage venture firm investing in climate/sustainability and infrastructure software. Comparable to Reaction Catalyst Fund given shared seed-to-Series-A climate tech focus and LP base orientation.
- Energy Impact Partners: Global venture platform investing in decarbonization across energy, mobility, and buildings. Direct competitor on the climate-investment side, particularly relevant given Reaction's portfolio includes grid-tech (Splight).
- SJF Ventures: Impact-focused VC backing high-growth companies in cleantech, health, and education. Comparable multi-thematic impact mandate and similar stage focus to Reaction's W250 Fund.
Broad incumbents
- Khosla Ventures: One of the largest and most established impact/tech VC firms, with deep climate tech exposure (Tesla early investor). Comparable in dual impact/return mandate and willingness to invest in science-driven deep tech, but at much greater scale.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat5 records
Key risks5 records
Key highlights7 records
Customer concentration
Reaction social profiles
Digital presenceReaction financial estimates
Financial estimateRevenue estimate
Valuation estimate
Reaction leadership team
Management profileNumber of profiles
Profiles20 records
Reaction funding detail
Funding detailFunding overview
Funding rounds
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Reaction M&A and investment
M&A and investmentM&A
Investments10 records
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Reaction
What does Reaction do?
Reaction is a venture capital firm that operates two investment funds—W250 Venture (Fund I) and the Climate Innovations Catalyst Fund (Fund II)—providing capital, global network access, and operational support to early-stage and growth-stage startups. The firm sources deals primarily through a community of more than 200 Stanford GSB alumni partners across 50 countries, targeting ventures in health technology, climate innovation, enterprise technology, and education technology that align with its mission to measurably improve one billion lives within a decade.
Is Reaction a public or private company?
Reaction is a private company. It is classified as founder individual operated bootstrapped and is currently operating.
When was Reaction founded?
Reaction was founded in 2020. It employs 251 to 500 people.
Where is Reaction based?
Reaction is headquartered in Palo Alto, United States, in the North America region.
How does Reaction make money?
One revenue line is on record: venture Capital Returns.
Who are Reaction's main competitors?
Direct peers on record are DBL Partners, Obvious Ventures, Breakthrough Energy Ventures, DCVC (Data Collective), Prime Movers Lab, Clean Energy Ventures, Congruent Ventures, Energy Impact Partners and SJF Ventures. Khosla Ventures is listed as a broad incumbent.
Does Reaction have an API?
No public API is recorded for Reaction.
What industry is Reaction in?
Reaction's product category is Venture Capital / Impact Investing. Its primary akta.pro industry code is FSANAAAG, Impact / ESG Venture Capital, with a secondary code of FSANAJAA, Climate / Clean Tech & Decarbonization Funds. Its NAICS code is 523150 and its SIC code is 6282.