Creative Biogene

What Creative Biogene does

Creative Biogene is a privately held biotechnology company founded in 2004 and headquartered in Shirley, NY, that operates as an integrated CRO/CDMO serving academic research institutions, pharmaceutical companies, biotechnology firms, and contract manufacturers across more than 40 countries. The company supports workflows spanning gene editing, viral vector production, stable cell line generation, recombinant protein expression, antibody engineering, and GMP-grade biologics manufacturing.

Its technology stack is anchored by several proprietary, trademarked platforms: the CRISPR/Cas9 Platform CB for gene knockout/knockin programs across difficult-to-transfect and tumor cell lines; the QVirusTM platform for AAV, lentivirus, adenovirus, and retrovirus design and manufacturing; the IntegrateRNA platform for RNA discovery and expression analysis; and emerging AI-driven tools for sgRNA design and antibody engineering. The catalog comprises over 4,000 stable cell lines, 50,000+ viral vectors, and 500+ validated recombinant drug target proteins, with documented CHO cell line productivity of 6–8 g/L for mAbs over 30+ generations and recombinant protein purity above 95% with endotoxin levels below 1.0 EU/µg.

Revenue is generated through four streams: catalog research products (one-time purchase of cell lines, viral particles, recombinant proteins, enzymes, kits, clones, and oligonucleotides); custom research services billed per project (stable cell line generation, gene editing, custom viral packaging, nucleotide synthesis, antibody services); CDMO services (cGMP cell line development, GMP plasmid, mRNA, and viral vector manufacturing for clinical and commercial use); and AI-enabled drug discovery services. Pricing is quote-based and not publicly disclosed. The company markets directly through its website using an inquiry/quote-based sales model, complemented by 24/7 technical customer support, and claims a customer base of 400+ clients across 50+ regions with US operations in Shirley, NY and European operations in Kriftel/Frankfurt, Germany.

Name

Creative Biogene

Legal name

Creative Biogene

Website

https://creative-biogene.com

Company type

Private

Founded year

2004

Operating status

Operating

Headcount range

1–10 employees

Short description

Creative Biogene is a privately held CRO/CDMO providing molecular biology research products and custom services — including gene editing, viral vectors, stable cell lines, recombinant proteins, and GMP biologics manufacturing — to academic, pharmaceutical, and biotechnology customers across 40+ countries.

Ownership category

akta.pro rank

Product category

Biotechnology Contract Research, Development, and Manufacturing (CRO/CDMO)

NAICS

Research and Development in Biotechnology (except Nanobiotechnology) (541714), Scientific Research and Development Services (5417), Biological Product (except Diagnostic) Manufacturing (325414)

SIC

Biological Products, (No Disgnostic Substances) (2836), Services-Commercial Physical & Biological Research (8731)

akta.pro primary industry

Gene Therapy (Viral Vector/Plasmid) CDMO (HLAGABAE)

akta.pro secondary industries

mRNA & Nucleic Acid Manufacturing Services (mRNA/saRNA/Plasmid DNA) (HLAGAGAC), Viral Vector Manufacturing Services (AAV, lentiviral, adenoviral) (HLAAAKAD), mRNA/LNP & Nucleic Acid Therapeutics CDMO (HLAGABAF)

Keywords

• Molecular biology reagents
• Gene editing services
• Viral vector manufacturing
• Cell line development
• Recombinant protein production

Headquarters

HQ city

Shirley

HQ country

United States

HQ region

North America

Offices2 records

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Operations, Technology or R&D, Infrastructure, Marketing or Sales

Revenue model

1. Research Products: Sale of molecular biology reagents and research tools including stable cell lines, viral particles, recombinant proteins, enzymes, kits, clones, and oligonucleotides. One-time product purchases with repeat customer base.
2. Custom Research Services: CRO services including stable cell line generation, custom viral packaging, gene editing, nucleotide synthesis, and protein production. Professional services billed per project.
3. CDMO Services: Contract manufacturing services for biologics including GMP plasmid production, GMP viral vector manufacturing, GMP mRNA production, and cell line development for clinical and commercial applications.
4. AI-Enabled Drug Discovery: AI-driven services for gene editing, antibody engineering, enzyme optimization, and small molecule screening.

Go-to-market motion1 record

Distribution channels1 record

Marketing channels4 records

Core offering

Creative Biogene manufactures and sells a broad catalog of molecular biology research products — including stable cell lines, viral particles, recombinant proteins, kits, enzymes, clones, aptamers, and adjuvants — and provides contract research (CRO) and contract development/manufacturing (CDMO) services for gene editing, viral vector production, custom RNA, antibody/protein degrader development, biosafety testing, and GMP biomanufacturing. Its proprietary platforms (CRISPR/Cas9 PlatformCB, QVirusTM, IntegrateRNA, Microbiology, Zebrafish) underpin offerings for academic, government, and pharmaceutical/biotech customers across 40+ countries.

Product overview

Creative Biogene is a comprehensive life science biotechnology company offering a broad portfolio of molecular biology products and research services. The product portfolio spans transfected stable cell lines (gene knockdown, knockout, and overexpression), premade viral particles (AAV, lentivirus, adenovirus, retrovirus), virus-like particles (VLPs) for vaccine development, oligonucleotide products, RNA interference products, recombinant drug target proteins (500+ validated targets), clones, laboratory kits, enzymes, aptamers, and adjuvants. The company also provides extensive CRO services including stable cell line generation, custom viral services, gene editing services, custom RNA services, biosafety testing, and aptamer discovery. CDMO services include HEK293 cell-based production, cGMP cell line development, GMP mRNA/plasmid/viral vector manufacturing. Key technology platforms include QVirusTM for viral vectors, IntegrateRNA for RNA research, CRISPR/Cas9 for gene editing, and specialized microbiology and zebrafish platforms.

Differentiator

Problem solved

Functional benefit

Brands

• Qirus™: High-titer viral vector packaging solutions for gene delivery across diverse cell types, from custom designs to large-scale production.
• IntegrateRNA
• Microbiology Platform
• Zebrafish Platform
• CRISPR/Cas9 PlatformCB
• QVirusTM

Products and services

• Transfected Stable Cell Lines

Named customers3 records

Segments3 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature8 records

Scale indicators11 records

Recent moves1 record

Expansion highlights6 records

Broad incumbents

• Abcam: Abcam (now part of Danaher) is a leading research antibody and reagent provider with growing offerings in cell engineering tools and recombinant proteins. It competes with Creative Biogene's antibody, recombinant protein, and cell line reagents at significantly greater scale.
• Bio-Techne: Bio-Techne is a large, publicly traded life sciences tools company with a deep catalog of proteins, antibodies, kits, and cell/gene therapy reagents including GMP-grade proteins. It overlaps Creative Biogene's recombinant protein and cell biology product lines as a much larger incumbent.
• WuXi AppTec: WuXi AppTec is one of the largest global CRO/CDMOs providing preclinical services, biologics manufacturing, viral vector CDMO, and cell therapy services. It represents the scale ceiling against which Creative Biogene's CDMO growth ambitions must compete.
• Lonza: Lonza is a global leader in biologics and cell & gene therapy CDMO with extensive GMP viral vector, mRNA, and cell therapy manufacturing capacity. It is a benchmark CDMO incumbent that defines the competitive context for Creative Biogene's GMP manufacturing ambitions.
• Eurofins Scientific: Eurofins is a large global life sciences testing and CRO group providing bioanalytical, biosafety, and molecular biology services. It overlaps Creative Biogene's biosafety testing, custom viral, and recombinant protein service lines as a much larger diversified vendor.

Direct peers

• GenScript: GenScript is a direct competitor offering gene synthesis, recombinant protein production, cell line engineering, and a CDMO division (GenScript ProBio) for viral vectors and cell therapy manufacturing. It mirrors Creative Biogene across nearly every major revenue stream from catalog reagents to GMP manufacturing.
• Sino Biological: Sino Biological is a leading recombinant protein manufacturer and CRO/CDMO offering custom protein services, viral vector production, and antibody development. It competes head-to-head with Creative Biogene's recombinant protein catalog and custom antibody/viral services.
• OriGene Technologies: OriGene offers cDNA clones, ORF clones, recombinant proteins, antibodies, and viral vectors for research use. Its catalog reagent business and custom service model closely overlap Creative Biogene's product portfolio in gene and protein research tools.
• ATCC: ATCC is a global biological materials resource providing cell lines, microbial cultures, and bioproducts. As a primary supplier of authenticated cell lines and reference standards, it competes directly with Creative Biogene's stable cell line catalog and bioresearch tools offering.
• Cell Biolabs: Cell Biolabs offers viral vectors, cell-based assays, recombinant proteins, and custom CRO services for life science research. Its focus on viral particles and assay-ready tools mirrors Creative Biogene's premade virus particles and recombinant drug target protein catalog.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat6 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/creativebiogene
• Facebookfacebook.com/402553579832485
• LinkedInlinkedin.com/company/creative-biogene

Revenue estimate

Valuation estimate

Number of profiles

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Creative Biogene