Creative Biolabs
Creative Biolabs is a private contract research organization based in Shirley, NY providing custom antibody discovery, engineering, characterization, and biomanufacturing services to pharmaceutical, biotech, and academic clients globally. The firm operates proprietary platforms spanning phage display, hybridoma, bispecific engineering, CAR-T, and lipid-based drug delivery.
- Company typePrivate
- Founded2014
- HeadquartersShirley, United States
- Headcount51–100
- GTM typeB2B
- OfferingServices
What Creative Biolabs does
Creative Biolabs is a private contract research organization (CRO) founded in 2014 and headquartered in Shirley, New York, that provides custom antibody discovery, engineering, characterization, and biomanufacturing services to pharmaceutical, biotechnology, and academic clients. The company serves a global customer base concentrated in North America and Europe, with two primary segments (pharma/biotech companies building antibody pipelines and academic/research institutions requiring reagents and platforms) and two secondary segments (cell and gene therapy developers and neuroscience-focused researchers). The firm has scaled to approximately 51-100 employees, roughly 100 service points, and a customer base whose work has been cited in 294 peer-reviewed articles or patents.
The company operates a portfolio of more than 18 proprietary platforms that span the antibody development continuum. Antibody discovery is anchored by Hyperdoma™ (electrofusion-based high-throughput hybridoma delivering 10³-10⁴ positive clones per fusion), Hi-Affi Hybridoma™ (50-200 clones per fusion via Magic Mouse Adjuvant), Hi-Affi™ phage display libraries with 10^10-10^12 independent clone diversity, yeast display, single B cell sorting, and transgenic mice. Engineering and characterization tools include Afuco™ for ADCC-enhanced non-fucosylated antibodies, iCrea™ standardized reporter cell lines, active antigen clearance with pH-dependent half-life extension, an Fc Silent platform for autoimmune applications, and AI-driven bispecific design achieving >90% heterodimerization efficiency. Adjacent platforms include NeuroST™ (3D neural organoids plus gene editing and microfluidics), LipoDrive™ (microfluidics-based liposome manufacturing), LNP platforms with 3x gene knockdown gains, GMP CAR-T solutions, oncolytic virus construction (adenoviral and HSV), circRNA analysis, and an end-to-end biosimilar CDMO offering. A notable technical specialization is expression and stabilization of difficult membrane protein targets (GPCRs, ion channels, transporters) under the MemDX™ banner.
Creative Biolabs generates revenue through two streams: project-based contract research services sold to enterprise clients via direct engagement with 24/7 scientific support, and product sales of ready-to-use items (phage and yeast display library kits, recombinant antibodies, membrane proteins, stable cell lines, ADC products) through its online catalog. Pricing is custom and quote-based; no standard tiers are disclosed. GTM combines 24/7 consultative sales, content marketing via the company blog, and active participation in major industry conferences (PEGS, World ADC, Antibody Engineering & Therapeutics, IO360, WRIB, Yale Innovation Summit, NIH Vendor Expo). The company holds ISO 9001:2015 certification for its quality management system.
Creative Biolabs firmographics
Firmographics- Name
- Creative Biolabs
- Legal name
- Creative Biolabs
- Website
- https://creative-biolabs.com
- Company type
- Private
- Founded year
- 2014
- Operating status
- Operating
- Headcount range
- 51–100 employees
- Short description
- Creative Biolabs is a private contract research organization based in Shirley, NY providing custom antibody discovery, engineering, characterization, and biomanufacturing services to pharmaceutical, biotech, and academic clients globally. The firm operates proprietary platforms spanning phage display, hybridoma, bispecific engineering, CAR-T, and lipid-based drug delivery.
- Ownership category
- akta.pro rank
Creative Biolabs industry classification
Industry- Product category
- Contract Research Services (Antibody Discovery & Biologics)
- NAICS
- Research and Development in Biotechnology (except Nanobiotechnology) (541714), Scientific Research and Development Services (5417), Biological Product (except Diagnostic) Manufacturing (325414)
- SIC
- Services-Commercial Physical & Biological Research (8731)
- akta.pro primary industry
- Clinical CROs (Phase I–IV) (HLAGAAAA)
- akta.pro secondary industries
- Specialty Therapeutic-Area CROs (e.g., oncology/rare disease) (HLAGAAAL), Antibody Discovery & Engineering Platforms (display tech, bispecifics, Fc engineering) (HLAAAIAB), Protein Engineering & Directed Evolution Platforms (enzyme/therapeutic protein optimization) (HLAAAIAC), Engineered Protein Therapeutics (de novo/AI-designed proteins, novel scaffolds) (HLAAAAAJ), Automation, Controls & Manufacturing Execution for Bioprocessing (SCADA/DCS/PLC/MES) (HLAAAJAE), Synthetic Biology & Genetic Circuit Design Platforms (pathway engineering, chassis development) (HLAAAIAD)
Keywords
Where Creative Biolabs is headquartered
LocationHeadquarters
- HQ city
- Shirley
- HQ country
- United States
- HQ region
- North America
Offices2 records
Markets served
Creative Biolabs business model
Business model- GTM type
- B2B
- Offering type
- Services
- Cost components
- Personnel, Operations, Technology or R&D, Marketing or Sales, Infrastructure
Revenue model
- Contract Research Services (CRO): Creative Biolabs operates as a contract research organization providing custom biotechnology and pharmaceutical services. The company offers a comprehensive suite of services including antibody discovery, characterization, engineering, and manufacturing. Revenue is generated through project-based contracts with pharmaceutical companies, biotech firms, and academic institutions requiring specialized research services.
- Product Sales: The company sells ready-to-use products including phage display library kits, yeast display library kits, recombinant antibodies, membrane proteins, stable cell lines, and VLP products for research applications.
Go-to-market motion2 records
Distribution channels2 records
Marketing channels5 records
Creative Biolabs product offering
Product offeringCore offering
Creative Biolabs is a contract research organization (CRO) that delivers custom antibody discovery, engineering, characterization, and manufacturing services for pharmaceutical, biotechnology, and academic clients. The company offers proprietary platforms spanning phage display, hybridoma (Hyperdoma™, Hi-Affi Hybridoma™), yeast display, single B cell sorting, and transgenic mice systems to generate monoclonal, bispecific, and single domain antibodies, complemented by gene therapy, cell therapy, viral vector, biosimilar, and lipid nanoparticle delivery services.
Product overview
Creative Biolabs is a contract research organization (CRO) providing custom biotechnology and pharmaceutical services. The company offers an integrated platform of antibody discovery services including phage display, yeast display, hybridoma technology (Hyperdoma™ and Hi-Affi Hybridoma™), single B cell sorting, and transgenic mice platforms. Their service portfolio spans antibody engineering (humanization, Fc engineering via Afuco™ technology, iCrea™ cell lines), bispecific antibody development, CAR-T therapy development (including GMP manufacturing and artificial T-cell stimulation platforms), gene therapy (viral vectors, oncolytic viruses, circRNA platforms), and bioconjugation/LNP delivery platforms. They provide comprehensive virus-like particle production across multiple expression systems, biosimilar development and CDMO services, and a wide range of research products including recombinant antibodies, membrane proteins, stable cell lines, and phage/yeast display library kits. Their recent launches include NeuroST™ for neurological disease research, LipoDrive™ for liposome manufacturing, and lipid-based drug delivery platforms (Ethosomes, Transfersomes, Transethosomes). The company operates specialized platforms for membrane protein discovery, antibody characterization, and functional analysis to support drug discovery from early discovery through preclinical development.
Differentiator
Problem solved
Functional benefit
Brands
- NeuroST™: Advanced 3D organoid platform for neurological disease research and drug discovery using gene editing, microfluidic technology, and detailed analytical tests.
- Hyperdoma™
- Hi-Affi Hybridoma™
- LipoDrive™
- Afuco™
- iCrea™
- Hi-Affinity™
- MemDX™
Products and services
- Antibody Discovery Services Comprehensive custom services for de novo antibody discovery using phage display, yeast display, hybridoma, single B cell sorting, and transgenic mice platforms, for pharmaceutical, biotech, and academic clients.
- Antibody Engineering Services Custom antibody humanization, caninization, camelization, simianization, murinization, Fc engineering, and affinity maturation services for therapeutic antibody optimization.
- Antibody Characterization Services Binding, sequence, immunogenicity, and functional characterization services including affinity measurement, epitope mapping, paratope mapping, and specificity profiling.
- Membrane Protein Production Services Custom expression, stabilization, and preparation of difficult membrane protein targets including GPCRs, ion channels, and transporters for drug discovery research.
- Virus-Like Particle (VLP) Production Services Custom VLP production services across E. coli, yeast, insect cell, mammalian cell, and plant cell expression systems for vaccine and drug delivery research.
- Bispecific Antibody Development Services End-to-end bispecific antibody development services integrating AI-driven design with proprietary engineering platforms (Charge Pair and Orthogonal Fab interfaces) for next-generation immunotherapy.
- GMP CAR-T Development Solutions GMP-grade product and viral vector manufacturing solutions for CAR-T cell therapy development, supporting clinical production and viral vector design at the New York GMP facility.
- Oncolytic Virus Construction Services Custom construction and optimization of adenoviral and herpes simplex virus (HSV) oncolytic vectors for precision oncology applications.
- Bioconjugation and Lipid Nanoparticle (LNP) Delivery Services Custom bioconjugation and lipid nanoparticle (LNP) delivery platforms with refined linker chemistry and conjugation sites for antibody-siRNA conjugates and gene therapy research.
- Biosimilar Development and CDMO Services End-to-end biosimilar development and CDMO services covering molecular design through large-scale production for monoclonal antibodies and viral vectors, with advanced characterization capabilities.
- Human In Vitro Neuro Research Models Human iPSC-derived neural models, microglia phagocytosis assays, and organ-on-chip platforms for preclinical neuro drug discovery, neuroinflammatory response evaluation, and blood-brain barrier dynamics studies.
- Phage Display Library Kits Ready-to-use phage display library kits for direct screening of target-specific binders, available through the company online catalog.
- Yeast Display Library Kits Ready-to-use yeast display library kits for binder discovery and protein engineering research applications.
- Premade Antibody and Peptide Libraries Premade antibody and peptide libraries available for licensing or direct screening in binder discovery workflows.
- Recombinant Antibodies Catalog recombinant antibody products including those against GPCRs, transporters, ion channels, CAR-T targets, biomarkers, and CD proteins.
- Membrane Protein Products Catalog membrane protein products including GPCRs, ion channels, transporters, Fc receptors, HLA proteins, and MP-VLPs.
- Membrane Protein Stable Cell Lines Stable cell lines overexpressing membrane proteins including GPCRs, ion channels, immune checkpoints, and oncology targets for screening applications.
- Antibody-Drug Conjugate (ADC) Products Catalog antibody-drug conjugate (ADC) research products for cancer therapy development applications.
Quantifiable outcome
- Up to 10³ to 10⁴ positive clones per hybridoma fusion
- +9 more outcomes
Companies that use Creative Biolabs
Customer profileSegments4 records
Ideal customer profiles4 records
Creative Biolabs technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Feature18 records
Creative Biolabs partnerships and signals
Strategic signalScale indicators5 records
Recent moves6 records
Expansion highlights5 records
Creative Biolabs competitors and assessment
Company assessmentDirect peers
- GenScript: GenScript is a leading CRO/CDMO offering custom antibody discovery, gene synthesis, protein engineering, and cell therapy services. It is the closest direct peer to Creative Biolabs given its overlapping focus on antibody/phage display platforms and custom research services for pharma and academic clients.
- Abcam: Abcam is a major provider of research-grade antibodies, recombinant antibodies, and antibody-related services with strong catalog offerings comparable to Creative Biolabs' recombinant antibody and membrane protein product lines. Both serve academic and pharma researchers globally.
- Sino Biological: Sino Biological provides recombinant proteins, antibodies, and CRO services for life science research, with a strong catalog of recombinant antibodies and membrane protein reagents. It overlaps with Creative Biolabs in membrane protein targets, recombinant antibody products, and custom services.
Broad incumbents
- Bio-Techne: Bio-Techne is a large life science tools company offering proteins, antibodies, and reagents across research and diagnostics. While broader and more catalog-focused than Creative Biolabs, it competes in antibody reagents and protein-based services for the same buyer segments.
- WuXi AppTec: WuXi AppTec is a global CRO/CDMO with extensive capabilities spanning discovery, preclinical, and clinical services for biologics and small molecules. It is a much larger incumbent that competes with Creative Biolabs on antibody discovery and biologics manufacturing services.
- Charles River Laboratories: Charles River Laboratories is a major CRO offering discovery, safety assessment, and manufacturing services including biologics and cell therapy support. It competes broadly with Creative Biolabs' preclinical CRO services and CDMO offerings.
- Lonza: Lonza is a leading global CDMO with biologics and cell/gene therapy manufacturing capabilities. Its GMP manufacturing and viral vector production overlap directly with Creative Biolabs' emerging GMP CAR-T and viral vector services.
- Cell Signaling Technology: Cell Signaling Technology is an established antibody reagent company with strong catalog offerings for signaling and post-translational modification targets. It overlaps with Creative Biolabs' antibody catalog and PTM-specific antibody discovery services.
- Thermo Fisher Scientific: Thermo Fisher is the largest life sciences tools and CRO/CDMO provider through Patheon and PPD, offering end-to-end services from discovery through clinical manufacturing. It is a broad incumbent peer competing across Creative Biolabs' service categories.
Emerging players
- ProMab Biotechnologies: ProMab is a smaller CRO specializing in custom monoclonal antibody development, hybridoma, and recombinant antibody services. It is an emerging peer competing directly in the same niche custom antibody discovery market as Creative Biolabs.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat3 records
Key risks6 records
Key highlights7 records
Customer concentration
Creative Biolabs social profiles
Digital presenceCreative Biolabs compliance and trust
Trust signalCompliance1 record
Creative Biolabs financial estimates
Financial estimateRevenue estimate
Valuation estimate
Creative Biolabs leadership team
Management profileNumber of profiles
Creative Biolabs funding detail
Funding detailFunding overview
Funding rounds
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Creative Biolabs M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Creative Biolabs
What does Creative Biolabs do?
Creative Biolabs is a contract research organization (CRO) that delivers custom antibody discovery, engineering, characterization, and manufacturing services for pharmaceutical, biotechnology, and academic clients. The company offers proprietary platforms spanning phage display, hybridoma (Hyperdoma™, Hi-Affi Hybridoma™), yeast display, single B cell sorting, and transgenic mice systems to generate monoclonal, bispecific, and single domain antibodies, complemented by gene therapy, cell therapy, viral vector, biosimilar, and lipid nanoparticle delivery services.
Is Creative Biolabs a public or private company?
Creative Biolabs is a private company. It is classified as founder individual operated bootstrapped and is currently operating.
When was Creative Biolabs founded?
Creative Biolabs was founded in 2014. It employs 51 to 100 people.
Where is Creative Biolabs based?
Creative Biolabs is headquartered in Shirley, United States, in the North America region.
How does Creative Biolabs make money?
Two revenue lines are on record. Contract Research Services (CRO) is the primary driver. The others are product Sales.
Who are Creative Biolabs's main competitors?
Direct peers on record are GenScript, Abcam and Sino Biological. Broad incumbents are Bio-Techne, WuXi AppTec, Charles River Laboratories, Lonza, Cell Signaling Technology and Thermo Fisher Scientific. ProMab Biotechnologies is listed as an emerging player.
Does Creative Biolabs have an API?
No public API is recorded for Creative Biolabs.
What industry is Creative Biolabs in?
Creative Biolabs's product category is Contract Research Services (Antibody Discovery & Biologics). Its primary akta.pro industry code is HLAGAAAA, Clinical CROs (Phase I–IV), with a secondary code of HLAGAAAL, Specialty Therapeutic-Area CROs (e.g., oncology/rare disease). Its NAICS code is 541714 and its SIC code is 8731.