Pressure BioSciences

What Pressure BioSciences does

Pressure BioSciences, Inc. (OTCQB: PBIO) is a publicly traded life sciences instrumentation company headquartered at 480 Neponset St., Canton, Massachusetts. The business traces its origins to Boston Biomedica, founded in 1978 by Richard T. Schumacher, and was restructured under the Pressure BioSciences name in 2004. The company develops and commercializes three patented, pressure-based technology platforms: Pressure Cycling Technology (PCT) for biological sample preparation, the BaroFold (PreEMT) platform for high-pressure protein refolding of therapeutic proteins, and Ultra Shear Technology (UST) for nanoemulsion manufacturing of oil-in-water formulations. Its flagship instrument, the Barocycler 2320EXT, is a benchtop system that processes up to 16 samples simultaneously using PCT MicroTubes. The company reports more than 300 PCT systems installed in approximately 200 academic, government, pharmaceutical, and biotech research sites worldwide, supported by an IP estate of 24+ issued US patents and 32+ pending applications and a 488+ document publications library with 120+ peer-reviewed citations of the PCT platform.

The company generates revenue through four primary streams: instrument sales (Barocycler 2320EXT, BaroShear K45), contract research services using BaroFold protein-refolding technology, licensing of platform IP, and, since the January 2024 acquisition of Uncle Bud's, direct-to-consumer sales of natural wellness products (CBD skincare, beverages, pet care) via the Uncle Bud's brand and e-commerce storefront. Distribution is hybrid: direct enterprise sales and contract services are supplemented by an exclusive distributor network covering Japan (Veritas), China (PRS International Trade), Europe (bioanalytic), South Korea (SCINCO), and Austria (Oroboros). Pricing is quote-based and not publicly disclosed.

In January 2024, Pressure BioSciences acquired Uncle Bud's Health & Wellness, signaling a strategic pivot toward faster-moving consumer categories while continuing to serve its installed base of life sciences customers. The company is led by founder and CEO Richard T. Schumacher, with Dr. Alexander Lazarev as Chief Science Officer, Jeffrey N. Peterson as Chairman, and Edmund Ting as Senior VP of Engineering. Financial scale remains small: one disclosed revenue reference is approximately $1.98 million against a cumulative net loss footprint of $29.31 million, with headcount of 11-50.

Name

Pressure BioSciences

Legal name

Pressure BioSciences, Inc.

Website

https://pressurebiosciences.com

Company type

Public

Founded year

1978

Operating status

Operating

Headcount range

11–50 employees

Short description

Pressure BioSciences (OTCQB: PBIO) develops patented pressure-based instrumentation for life sciences, including the PCT, BaroFold, and UST platforms. It serves pharma, biotech, academic, and government laboratories, and since 2024 also sells consumer wellness products through its Uncle Bud's subsidiary.

Ownership category

akta.pro rank

Product category

Laboratory Instrumentation

NAICS

Analytical Laboratory Instrument Manufacturing (334516), Navigational, Measuring, Electromedical, and Control Instruments Manufacturing (33451), Research and Development in Biotechnology (except Nanobiotechnology) (541714)

SIC

Laboratory Analytical Instruments (3826), Services-Commercial Physical & Biological Research (8731), Laboratory Apparatus & Furniture (3821)

akta.pro primary industry

Sample Preparation, Storage & Cryogenics (Freezers, Cryovials, Cryostats) (HLAGAIAJ)

akta.pro secondary industries

General Lab Equipment (Centrifuges, Incubators, Shakers, Ovens) (HLAGAIAC), Upstream Bioprocessing Systems & Equipment (cell culture/fermentation, bioreactors, feeds/media) (HLAAAJAA), Analytical Development & QC Testing (Release/Stability/Potency) (HLAGAGAF), Raw Materials & Critical Reagents Supply Services (media, resins, single-use) (HLAAAKAI)

Keywords

• Pressure cycling technology
• Laboratory sample preparation
• Protein refolding instruments
• Nanoemulsion processing equipment
• Biotherapeutic manufacturing tools

Headquarters

HQ city

Canton

HQ country

United States

HQ region

North America

Offices2 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Revenue model

1. Instrument Sales: Sale of pressure-based instruments including Barocycler 2320EXT and BaroShear K45 for research and commercial applications in life sciences.
2. Contract Services: BaroFold technology offered through contract services for protein refolding and therapeutic protein development for industry partners.
3. Consumer Health Products: Revenue from Uncle Bud's health and wellness brand including CBD-based skincare, beverages, and pet care products.
4. Licensing: Research and manufacturing licenses available for BaroFold and other technology platforms.

Go-to-market motion2 records

Distribution channels8 records

Marketing channels6 records

Core offering

Pressure BioSciences develops, manufactures, and sells proprietary pressure-based laboratory instrumentation, including the Barocycler 2320EXT and BaroShear K45 systems, alongside consumables and contract research services. The instruments support biological sample preparation, high-pressure protein refolding (BaroFold), and nanoemulsion manufacturing (Ultra Shear Technology) for the worldwide life sciences industry. The company also markets consumer health and wellness products through its acquired Uncle Bud's subsidiary.

Product overview

Pressure BioSciences is a life sciences instrumentation company offering three patented pressure-based platform technologies: the PCT (Pressure Cycling Technology) Platform for biological sample preparation, the BaroFold Platform for high-pressure protein refolding, and the UST (Ultra Shear Technology) Platform for nanoemulsion manufacturing. The core product is the Barocycler 2320EXT instrument, supplemented by the Baroshear K45 for CBD nanoemulsion preparation. Through its subsidiary Uncle Bud's, the company also offers consumer wellness products. Services include contract research using BaroFold technology. The company serves academic, government, pharmaceutical, and biotech research laboratories worldwide.

Differentiator

Problem solved

Functional benefit

Brands

• BaroShear K45: Instrument for efficient preparation of high quality, water-soluble nanoemulsions of CBD oil
• BaroFold
• PreEMT
• Barocycler 2320EXT
• Uncle Bud's

Quantifiable outcome

• 300+ PCT instrument systems placed in 200+ research sites worldwide
• +2 more outcomes

Named customers4 records

Segments5 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature4 records

Partnerships

Seven partnerships are on record, tiered core and minor.

• Uncle Bud'scoreStrategic or Co-development Partner · 11 January 2024Acquisition of Uncle Bud's, a natural wellness brand, to integrate UltraShear technology into consumer health products. Transaction involves exchange of preferred stock convertible into common shares with performance-based earnouts. Combined entity aims to expand into skincare, beverages, and pet care markets. Transaction expected to close by January 19, 2024.
• Vita-FortecoreStrategic or Co-development Partner · 1 January 2024Partnership with Vita-Forte, the largest global supplier of freeze-dried Acai, to commercialize highly potent, multi-antioxidant UltraShear (UST) nanoemulsion oral spray product.
• Veritas, Inc.coreChannel Partner/ Reseller/ DistributorExclusive distributor agent for Japan handling distribution of Pressure BioSciences products in the Japanese market.
• PRS International Trade (Shanghai) Co.,LtdcoreChannel Partner/ Reseller/ DistributorExclusive distributor agent for China handling distribution of Pressure BioSciences products in the Chinese market.
• bioanalyticcoreChannel Partner/ Reseller/ DistributorExclusive distributor agent for Europe handling distribution of Pressure BioSciences products across European markets.
• SCINCOcoreChannel Partner/ Reseller/ DistributorExclusive distributor agent for South Korea handling distribution of Pressure BioSciences products in the Korean market.
• OroborosminorChannel Partner/ Reseller/ DistributorDistributes SHREDDER SG3 and Shredder Tubes only in Austria, representing a limited distribution arrangement for specific products.

Scale indicators7 records

Recent moves5 records

Expansion highlights5 records

Market position

Competitive moat3 records

Key highlights7 records

Customer concentration

• Xx.com/presbiosciences
• YouTubeyoutube.com/user/pbiopr
• Facebookfacebook.com/207241745959264
• LinkedInlinkedin.com/company/pressure-biosciences-inc

Revenue estimate

Valuation estimate

Number of profiles

Subsidiaries1 record

Funding overview

Funding rounds8 records

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A3 records

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Pressure BioSciences