Pressure BioSciences
Pressure BioSciences (OTCQB: PBIO) develops patented pressure-based instrumentation for life sciences, including the PCT, BaroFold, and UST platforms. It serves pharma, biotech, academic, and government laboratories, and since 2024 also sells consumer wellness products through its Uncle Bud's subsidiary.
- Company typePublic
- Founded1978
- HeadquartersCanton, United States
- Headcount11–50
- GTM typeB2B
- OfferingHardware or Manufacturing
What Pressure BioSciences does
Pressure BioSciences, Inc. (OTCQB: PBIO) is a publicly traded life sciences instrumentation company headquartered at 480 Neponset St., Canton, Massachusetts. The business traces its origins to Boston Biomedica, founded in 1978 by Richard T. Schumacher, and was restructured under the Pressure BioSciences name in 2004. The company develops and commercializes three patented, pressure-based technology platforms: Pressure Cycling Technology (PCT) for biological sample preparation, the BaroFold (PreEMT) platform for high-pressure protein refolding of therapeutic proteins, and Ultra Shear Technology (UST) for nanoemulsion manufacturing of oil-in-water formulations. Its flagship instrument, the Barocycler 2320EXT, is a benchtop system that processes up to 16 samples simultaneously using PCT MicroTubes. The company reports more than 300 PCT systems installed in approximately 200 academic, government, pharmaceutical, and biotech research sites worldwide, supported by an IP estate of 24+ issued US patents and 32+ pending applications and a 488+ document publications library with 120+ peer-reviewed citations of the PCT platform.
The company generates revenue through four primary streams: instrument sales (Barocycler 2320EXT, BaroShear K45), contract research services using BaroFold protein-refolding technology, licensing of platform IP, and, since the January 2024 acquisition of Uncle Bud's, direct-to-consumer sales of natural wellness products (CBD skincare, beverages, pet care) via the Uncle Bud's brand and e-commerce storefront. Distribution is hybrid: direct enterprise sales and contract services are supplemented by an exclusive distributor network covering Japan (Veritas), China (PRS International Trade), Europe (bioanalytic), South Korea (SCINCO), and Austria (Oroboros). Pricing is quote-based and not publicly disclosed.
In January 2024, Pressure BioSciences acquired Uncle Bud's Health & Wellness, signaling a strategic pivot toward faster-moving consumer categories while continuing to serve its installed base of life sciences customers. The company is led by founder and CEO Richard T. Schumacher, with Dr. Alexander Lazarev as Chief Science Officer, Jeffrey N. Peterson as Chairman, and Edmund Ting as Senior VP of Engineering. Financial scale remains small: one disclosed revenue reference is approximately $1.98 million against a cumulative net loss footprint of $29.31 million, with headcount of 11-50.
Pressure BioSciences firmographics
Firmographics- Name
- Pressure BioSciences
- Legal name
- Pressure BioSciences, Inc.
- Website
- https://pressurebiosciences.com
- Company type
- Public
- Founded year
- 1978
- Operating status
- Operating
- Headcount range
- 11–50 employees
- Short description
- Pressure BioSciences (OTCQB: PBIO) develops patented pressure-based instrumentation for life sciences, including the PCT, BaroFold, and UST platforms. It serves pharma, biotech, academic, and government laboratories, and since 2024 also sells consumer wellness products through its Uncle Bud's subsidiary.
- Ownership category
- akta.pro rank
Pressure BioSciences industry classification
Industry- Product category
- Laboratory Instrumentation
- NAICS
- Analytical Laboratory Instrument Manufacturing (334516), Navigational, Measuring, Electromedical, and Control Instruments Manufacturing (33451), Research and Development in Biotechnology (except Nanobiotechnology) (541714)
- SIC
- Laboratory Analytical Instruments (3826), Services-Commercial Physical & Biological Research (8731), Laboratory Apparatus & Furniture (3821)
- akta.pro primary industry
- Sample Preparation, Storage & Cryogenics (Freezers, Cryovials, Cryostats) (HLAGAIAJ)
- akta.pro secondary industries
- General Lab Equipment (Centrifuges, Incubators, Shakers, Ovens) (HLAGAIAC), Upstream Bioprocessing Systems & Equipment (cell culture/fermentation, bioreactors, feeds/media) (HLAAAJAA), Analytical Development & QC Testing (Release/Stability/Potency) (HLAGAGAF), Raw Materials & Critical Reagents Supply Services (media, resins, single-use) (HLAAAKAI)
Keywords
Where Pressure BioSciences is headquartered
LocationHeadquarters
- HQ city
- Canton
- HQ country
- United States
- HQ region
- North America
Offices2 records
Markets served
Pressure BioSciences business model
Business model- GTM type
- B2B
- Offering type
- Hardware or Manufacturing
Revenue model
- Instrument Sales: Sale of pressure-based instruments including Barocycler 2320EXT and BaroShear K45 for research and commercial applications in life sciences.
- Contract Services: BaroFold technology offered through contract services for protein refolding and therapeutic protein development for industry partners.
- Consumer Health Products: Revenue from Uncle Bud's health and wellness brand including CBD-based skincare, beverages, and pet care products.
- Licensing: Research and manufacturing licenses available for BaroFold and other technology platforms.
Go-to-market motion2 records
Distribution channels8 records
Marketing channels6 records
Pressure BioSciences product offering
Product offeringCore offering
Pressure BioSciences develops, manufactures, and sells proprietary pressure-based laboratory instrumentation, including the Barocycler 2320EXT and BaroShear K45 systems, alongside consumables and contract research services. The instruments support biological sample preparation, high-pressure protein refolding (BaroFold), and nanoemulsion manufacturing (Ultra Shear Technology) for the worldwide life sciences industry. The company also markets consumer health and wellness products through its acquired Uncle Bud's subsidiary.
Product overview
Pressure BioSciences is a life sciences instrumentation company offering three patented pressure-based platform technologies: the PCT (Pressure Cycling Technology) Platform for biological sample preparation, the BaroFold Platform for high-pressure protein refolding, and the UST (Ultra Shear Technology) Platform for nanoemulsion manufacturing. The core product is the Barocycler 2320EXT instrument, supplemented by the Baroshear K45 for CBD nanoemulsion preparation. Through its subsidiary Uncle Bud's, the company also offers consumer wellness products. Services include contract research using BaroFold technology. The company serves academic, government, pharmaceutical, and biotech research laboratories worldwide.
Differentiator
Problem solved
Functional benefit
Brands
- BaroShear K45: Instrument for efficient preparation of high quality, water-soluble nanoemulsions of CBD oil
- BaroFold
- PreEMT
- Barocycler 2320EXT
- Uncle Bud's
Quantifiable outcome
- 300+ PCT instrument systems placed in 200+ research sites worldwide
- +2 more outcomes
Companies that use Pressure BioSciences
Customer profileNamed customers4 records
Segments5 records
Pressure BioSciences technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Feature4 records
Pressure BioSciences partnerships and signals
Strategic signalPartnerships
Seven partnerships are on record, tiered core and minor.
- Uncle Bud'scoreAcquisition of Uncle Bud's, a natural wellness brand, to integrate UltraShear technology into consumer health products. Transaction involves exchange of preferred stock convertible into common shares with performance-based earnouts. Combined entity aims to expand into skincare, beverages, and pet care markets. Transaction expected to close by January 19, 2024.
- Vita-FortecorePartnership with Vita-Forte, the largest global supplier of freeze-dried Acai, to commercialize highly potent, multi-antioxidant UltraShear (UST) nanoemulsion oral spray product.
- Veritas, Inc.coreExclusive distributor agent for Japan handling distribution of Pressure BioSciences products in the Japanese market.
- PRS International Trade (Shanghai) Co.,LtdcoreExclusive distributor agent for China handling distribution of Pressure BioSciences products in the Chinese market.
- bioanalyticcoreExclusive distributor agent for Europe handling distribution of Pressure BioSciences products across European markets.
- SCINCOcoreExclusive distributor agent for South Korea handling distribution of Pressure BioSciences products in the Korean market.
- OroborosminorDistributes SHREDDER SG3 and Shredder Tubes only in Austria, representing a limited distribution arrangement for specific products.
Scale indicators7 records
Recent moves5 records
Expansion highlights5 records
Pressure BioSciences competitors and assessment
Company assessmentMarket position
Competitive moat3 records
Key highlights7 records
Customer concentration
Pressure BioSciences social profiles
Digital presencePressure BioSciences financial estimates
Financial estimateRevenue estimate
Valuation estimate
Pressure BioSciences leadership team
Management profileNumber of profiles
Pressure BioSciences subsidiaries and ownership
Company hierarchySubsidiaries1 record
Pressure BioSciences funding detail
Funding detailFunding overview
Funding rounds8 records
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Pressure BioSciences M&A and investment
M&A and investmentM&A3 records
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Pressure BioSciences
What does Pressure BioSciences do?
Pressure BioSciences develops, manufactures, and sells proprietary pressure-based laboratory instrumentation, including the Barocycler 2320EXT and BaroShear K45 systems, alongside consumables and contract research services. The instruments support biological sample preparation, high-pressure protein refolding (BaroFold), and nanoemulsion manufacturing (Ultra Shear Technology) for the worldwide life sciences industry. The company also markets consumer health and wellness products through its acquired Uncle Bud's subsidiary.
Is Pressure BioSciences a public or private company?
Pressure BioSciences is a public company. It is currently operating.
When was Pressure BioSciences founded?
Pressure BioSciences was founded in 1978. It employs 11 to 50 people.
Where is Pressure BioSciences based?
Pressure BioSciences is headquartered in Canton, United States, in the North America region.
How does Pressure BioSciences make money?
Four revenue lines are on record. Instrument Sales are the primary driver. The others are contract Services, consumer Health Products and licensing.
Does Pressure BioSciences have an API?
No public API is recorded for Pressure BioSciences.
What industry is Pressure BioSciences in?
Pressure BioSciences's product category is Laboratory Instrumentation. Its primary akta.pro industry code is HLAGAIAJ, Sample Preparation, Storage & Cryogenics (Freezers, Cryovials, Cryostats), with a secondary code of HLAGAIAC, General Lab Equipment (Centrifuges, Incubators, Shakers, Ovens). Its NAICS code is 334516 and its SIC code is 3826.