YouScript

What YouScript does

YouScript Technologies, LLC is a US-based pharmacogenomics clinical decision support software company founded in 2004 and headquartered in Houston, Texas, with an additional office in Seattle, Washington. The company builds the YouScript Precision Prescribing platform, which integrates pharmacogenetic testing with drug-gene, drug-drug, multi-drug and drug-drug-gene interaction analysis to surface adverse-drug-event risk at the point of prescribing. Its underlying technology combines a patented prediction algorithm (US Patents 8,099,298 and 10,210,312), a curated knowledge base of more than 19,000 references covering roughly 2,000 unique drugs, herbals, OTCs and 90+ phenotypes, and a Population Risk Analysis Dashboard that stratifies at-risk patients. The platform is delivered through SMART on FHIR integrations with Epic, Cerner, Allscripts, PDX and Telus Health, alongside standalone web access and RESTful APIs.

YouScript generates revenue through annual and multi-year software subscriptions sold to individual prescribers (for example, $365 for a one-year provider subscription and $638 for a two-year subscription) and through enterprise licensing agreements with health systems, ACOs and health plans, supported by an enterprise field-sales motion. Its primary customer segments are health plans and ACOs, healthcare organizations, individual prescribers, and pharmacists, with named deployments including Group Health Cooperative of South Central Wisconsin, Highmark Health's VITAL Innovation Program, Clover Health and Stone Run Family Medicine. The company operates as a subsidiary of Aranscia, which acquired it from Invitae Corporation and now groups it with 2bPrecise, AccessDx Laboratory and Spesana; founder and President Kristine Ashcraft leads the business alongside Aranscia's CMO Joel Diamond and VP of Clinical Operations Houda Hachad.

Name

YouScript

Legal name

YouScript Technologies, LLC

Website

https://youscript.com

Company type

Private

Founded year

2004

Operating status

Operating

Headcount range

11–50 employees

Short description

YouScript Technologies is a US pharmacogenomics software company that provides clinical decision support for drug-gene and drug-drug interaction risk at the point of prescribing, serving health plans, health systems, prescribers and pharmacists through EHR-integrated subscriptions.

Ownership category

akta.pro rank

Product category

Pharmacogenomic Clinical Decision Support Software

NAICS

Software Publishers (513210)

SIC

Services-Prepackaged Software (7372)

akta.pro primary industry

Pharmacogenomics (PGx) Decision Support (HLAAANAB)

akta.pro secondary industries

Pharmacy Benefit Management (PBM) & Formulary Management IT (HLACAKAD), Pharmacogenomics-Informed Medication Optimization Support (HSABALAO), Specialty Pharmacy & Complex Therapy Management Platforms (HLACAKAG)

Keywords

• Pharmacogenomic decision support
• Precision prescribing software
• Clinical decision support tools
• Drug interaction analytics
• EHR-integrated medication management

Headquarters

HQ city

Seattle

HQ country

United States

HQ region

North America

Offices2 records

Markets served

GTM type

B2B

Offering type

Software

Cost components

Technology or R&D, Personnel, Marketing or Sales, Operations, Infrastructure

Revenue model

1. Software Subscription: Provider subscription model with annual and multi-year subscription options for healthcare providers and organizations. Subscriptions provide access to the YouScript Precision Prescribing platform including clinical decision support, risk analysis, and EHR integrations.
2. Enterprise Licensing: Multi-year enterprise contracts with health systems, ACOs, and health plans for organization-wide deployment of pharmacogenomic-guided clinical decision support tools.

Pricing tiers

Go-to-market motion3 records

Distribution channels7 records

Marketing channels6 records

Core offering

YouScript provides pharmacogenomic clinical decision support software that integrates drug-gene and drug-drug interaction analysis to help healthcare providers make safer prescribing decisions at the point of care. The platform is delivered as a SaaS subscription accessible directly or embedded inside major EHR systems (Epic, Cerner, Allscripts, PDX, Telus Health), and includes a Population Risk Analysis Dashboard for stratifying patient populations by genetic risk.

Product overview

YouScript is a precision medicine platform offering a suite of clinical decision support and pharmacogenomics products. The core product is YouScript Precision Prescribing Software, which integrates pharmacogenetic testing with drug-gene and drug-drug interaction information. Key add-on modules include the Risk Analysis Dashboard for population health management and the Alternatives Selector for recommending safer medications. The platform is integrated into major EHR systems (Epic, Cerner, Allscripts, PDX, Telus Health, GraneRx) via RESTful APIs with SMART on FHIR standards. YouScript offers Provider Subscriptions (1-year at $365, 2-year at $638) and supplements its product portfolio with educational content like the PGxperts Bytes video series and company blog. The platform synthesizes evidence on drug response including pharmacogenetic testing, drug-gene interactions, drug-drug interactions, and cumulative multi-drug and multi-gene interactions. YouScript is the only clinically validated system that shows improved outcomes, reduced costs, and high patient and provider satisfaction.

Differentiator

Problem solved

Functional benefit

Brands

• PGxperts™: A team of pharmacogenetics experts at YouScript with combined 100+ years of experience in pharmacogenetics, healthcare, and technology development.

Products and services

• YouScript Precision Prescribing Software Clinical decision support software that integrates pharmacogenetic testing with drug-gene and drug-drug interaction analysis to assess the cumulative impact of a patient's genetics and current drug regimen, presenting alerts and safer medication alternatives in an actionable format at the point of care. Sold to individual providers and enterprise healthcare organizations.
• Risk Analysis Dashboard Population health management tool that stratifies patient populations by genetic risk to identify polypharmacy patients at highest risk of adverse drug events, including a genetic risk identifier that assigns percentage likelihood testing will result in a change to drug or dose. Sold to health plans, ACOs, and healthcare organizations.
• DPYD Safety Update Capability within YouScript Precision Prescribing that helps oncologists comply with the FDA black box warning requiring DPYD genetic testing on patients receiving capecitabine (Xeloda), supporting identification of patients with DPYD variants and streamlining test ordering and reporting workflows.
• YouScript Provider Subscription Subscription service for individual healthcare providers to access the YouScript Precision Prescribing platform, available as a 1-year subscription at $365.00 or a 2-year subscription at $638.00, purchased through the YouScript website.

Quantifiable outcome

• 52% reduction in readmissions
• +8 more outcomes

Named customers4 records

Segments4 records

Ideal customer profiles4 records

Technology focussed Yes

API detail

Has API

Yes

API docs

API detail

Core technology

AI maturity

App detail

Integration6 records

AI capability6 records

Feature7 records

Partnerships

14 partnerships are on record, tiered core and minor.

• Group Health Cooperative of South Central WisconsincoreImplementation/ SI/ Consulting Partner · 15 January 2020First to implement and validate YouScript in Epic EHR. Multi-year contract through 2023 for drug and dose optimizations based on genetics and co-medication for at-risk patients in the region. Serves over 80,000 members.
• Genome MedicalminorStrategic or Co-development Partner · 1 January 2020Preferred partnership to provide end-to-end precision medicine solutions to health systems. Combines YouScript clinical decision support with Genome Medical's genetic services and analytics capabilities.
• PipelineRxminorStrategic or Co-development Partner · 25 June 2019Partnership to provide personalized prescribing capabilities integrated with PowerGridRx Platform and Patient Discharge Solution for medication management and telepharmacy services.
• GraneRxcoreStrategic or Co-development Partner · 1 August 2018Partnership to deliver precision prescribing support to post-acute care industry including long-term care facilities. GraneRx takes leading role in promoting patient safety through precision medicine.
• Clover HealthminorStrategic or Co-development Partner · 1 May 2018Partnership to deliver free gene-informed medication management for in-home primary care members. Clover's in-home primary care program supported by YouScript genomic testing capabilities to reduce adverse drug interactions.
• ElsevierminorStrategic or Co-development Partner · 2 February 2017Collaboration to incorporate gene-based prescribing and reduce alert fatigue. Elsevier content integrated with YouScript clinical decision support to bring individualized drug and dose optimization guidance.
• EpiccoreTechnology or IntegrationSmart on FHIR-enabled YouScript toolset integrated into Epic and Epic's Healthy Planet population health module. YouScript is available through Epic App Orchard and integrates directly with patient charts for seamless point-of-care prescribing support.
• CernercoreTechnology or IntegrationYouScript integrated into Cerner's PowerChart through Code Cerner developer network. SMART on FHIR-enabled integration designed to intelligently trigger and triage alerts to keep patients safe and reduce provider alert fatigue.
• AllscriptscoreTechnology or IntegrationPhase I and Phase II winner of Allscripts Open App Challenge. YouScript available through Allscripts Developer Partner program and Allscripts Store cloud platform.
• PDXcoreTechnology or IntegrationPartnership to deliver integrated YouScript precision prescribing clinical decision support to all PDX pharmacy software users. Pharmacists gain access to precision prescribing capabilities through their existing pharmacy management system.
• AransciacoreOthersAranscia acquired YouScript from Invitae. YouScript is now an Aranscia company along with 2bPrecise, AccessDx Laboratory, and Spesana. Aranscia delivers world-class diagnostic software, services, and testing innovations.
• AccessDx LaboratorycoreStrategic or Co-development PartnerPartner laboratory providing pharmacogenomic testing services when needed by YouScript customers. Part of Aranscia portfolio companies with expertise in molecular diagnostics and genomics.
• Highmark Health VITAL Innovation ProgramminorStrategic or Co-development PartnerHighmark Health's VITAL Innovation Program evaluating YouScript Precision Prescribing Software for patients taking multiple medications, with Premier Medical Associates spearheading evaluation among 3,000 patients.
• HealthXLminorOthersYouScript is a verified company with HealthXL, a healthcare technology verification and partnership platform connecting innovative companies with healthcare organizations.

Scale indicators12 records

Recent moves6 records

Expansion highlights6 records

Direct peers

• OneOme: OneOme offers the RightMed pharmacogenomic test and clinical decision support report, providing drug-gene interaction analysis to clinicians. It is a direct competitor in PGx decision support, serving similar health system and provider customers.
• Molecular Health: Molecular Health provides clinical decision support for precision medicine, including pharmacogenomic and oncology decision support. It overlaps with YouScript's drug-gene interaction analysis at the point of care.
• 2bPrecise: 2bPrecise is a pharmacogenomics and precision medicine clinical decision support platform and is an Aranscia sister company to YouScript. Both target similar health system customers with genomics-informed prescribing workflows.
• Translational Software: Translational Software (now part of Roper Technologies / Harris Healthcare) provides pharmacogenomic clinical decision support and reporting platforms. It directly competes with YouScript on PGx reporting and EHR-integrated decision support.
• Coriell Life Sciences: Coriell Life Sciences delivers pharmacogenomic interpretation services and clinical decision support tools to healthcare providers and health systems. It is a direct peer offering PGx-guided prescribing analytics.
• Tabula Rasa HealthCare (CareVention HealthCare): Tabula Rasa HealthCare's MedWise medication safety platform combines pharmacogenomics with multi-drug interaction science for at-risk patient populations. It directly competes in PGx-informed medication management for health plans and provider groups.

Broad incumbents

• First Databank (FDB): FDB provides comprehensive drug information databases (MedKnowledge) and clinical decision support tools widely embedded in EHRs. It is a broad incumbent in medication decision support and a competitor to YouScript's drug interaction analysis, though it does not specialize in pharmacogenomics.
• Merative (formerly IBM Micromedex): Merative's Micromedex is a clinical decision support suite offering drug interaction and medication safety content used widely in U.S. hospitals. It is a broad incumbent competing with YouScript on drug-drug interaction alerts and medication guidance.

Others

• Wolters Kluwer Clinical Drug Information (Lexicomp, Medi-Span): Wolters Kluwer's Lexicomp and Medi-Span products provide drug information and clinical decision support integrated into Epic, Cerner, and other EHRs. It is a broad incumbent that competes with YouScript's drug-drug interaction capabilities as part of a much larger portfolio.

Emerging players

• MedAware: MedAware applies machine learning to identify medication-related risks and reduce alert fatigue, an adjacent capability to YouScript's PGx decision support. It is an emerging player in AI-driven medication safety with partial functional overlap.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/youscript
• YouTubeyoutube.com/channel/UC5D6nAn2LyIWC2K-VLlZDuw
• Facebookfacebook.com/youscript
• LinkedInlinkedin.com/company/youscript

Compliance1 record

Revenue estimate

Valuation estimate

Number of profiles

Profiles4 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about YouScript