Zavation

Name

Zavation

Legal name

Zavation Medical Products, LLC

Website

http://zavation.com

Company type

Private

Founded year

2012

Operating status

Operating

Headcount range

51–100 employees

Ownership category

akta.pro rank

Product category

Spinal Implants and Biologics

NAICS

Surgical Appliance and Supplies Manufacturing (339113), Surgical and Medical Instrument Manufacturing (339112)

SIC

Orthopedic, Prosthetic & Surgical Appliances & Supplies (3842), Surgical & Medical Instruments & Apparatus (3841)

akta.pro primary industry

Spine Implants & Motion Preservation (Fusion/Disc/Interspinous) (HLAHAEAC)

akta.pro secondary industries

3D-Printed & Patient-Specific Implants (Custom Ortho/Spine/Cranial) (HLAHAEAJ), Open & Minimally Invasive Surgical Instruments (Handheld, Laparoscopic, MIS) (HLAHADAA)

Keywords

• Spinal implant manufacturing
• Fusion biologics
• Interbody devices
• Vertebroplasty systems
• Pedicle screw systems

Headquarters

HQ city

Flowood

HQ country

United States

HQ region

North America

Offices3 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Personnel, Operations, Technology or R&D, Marketing or Sales, Infrastructure

Revenue model

1. Spinal Implant Sales: Zavation designs, develops, manufactures and distributes spinal implants, instrumentation systems, and biologics. Revenue is generated through the sale of medical devices to healthcare providers via a national distributor network.

Go-to-market motion2 records

Distribution channels1 record

Marketing channels5 records

Core offering

Zavation designs, develops, manufactures, and distributes spinal implants, instrumentation systems, and biologics for spine surgery. Its portfolio addresses ACDF, ALIF, LLIF, PLIF/TLIF, corpectomy, posterior fixation, sacroiliac joint fusion, and vertebral augmentation procedures, and is delivered to surgeons and healthcare facilities through a national network of independent medical device distributors. Products are differentiated by proprietary material technologies (Mimetic Metal porous titanium, NanoPrime titanium-PEEK hybrid, Labyrinth porous PEEK) produced in vertically integrated facilities.

Product overview

Zavation is a medical device company that designs, develops, manufactures, and distributes spinal implant products and biologics through a distributor network. The portfolio is organized around key spinal procedure categories including ACDF (anterior cervical discectomy and fusion), ALIF (anterior lumbar interbody fusion), LLIF (lateral lumbar interbody fusion), PLIF/TLIF (posterior lumbar interbody fusion), corpectomy, posterior fixation, sacroiliac joint fusion, and vertebral augmentation. The product lineup features core technology platforms including NanoPrime titanium ion bond technology for PEEK-titanium hybrid interbodies, Mimetic Metal additively manufactured porous technology, and proprietary eZspand expandable cage technology. Key product families include the Varisync stand-alone ALIF system, Tiger 2 pedicle screw system, Lateral Fusion System with Vantage retractor and F3D/CL5 cages, Normandy VBR systems for corpectomy, SI joint fusion systems (Siber Ti, Entasis, SInapse), and ZVplasty balloon/cement systems for vertebral augmentation. Biologics offerings include Unifuze collagen strips and synthetic putty, Amnion Patch allograft, DBM products, and bone allograft materials. The company operates vertically integrated manufacturing facilities in Flowood, Mississippi and St. Louis, Missouri.

Differentiator

Problem solved

Functional benefit

Brands

• ChoiceSpine: A spinal implant company acquired by Zavation in 2026, operating independently under common ownership. Designs and manufactures spinal implant systems spanning cervical, thoracolumbar, and interbody applications.
• CoreLink

Products and services

• NanoPrime Labyrinth Cervical Interbody System Cervical interbody cage combining NanoPrime titanium ion bond technology with patented Labyrinth porous PEEK architecture, designed for spine surgeons performing ACDF procedures who want both PEEK and titanium biological benefits in one implant.
• Lateral Fusion System Complete procedural solution for lateral lumbar interbody fusion (LLIF), comprising the Vantage Lateral Retractor, F3D and CL5 lateral cages, and Oro Plate system, for spine surgeons treating lateral lumbar pathology.
• Tiger 2 Pedicle Screw System Versatile modular thoracolumbar pedicle screw fixation system with simplified instrumentation for degenerative, deformity, and revision spine surgeries.
• Siber Ti SI Joint Fusion System Sacroiliac joint fusion system featuring patented Swift Tip Technology, delivering tactile joint compression and 3D-printed Mimetic Metal surfaces engineered at macro, micro, and nano levels for SI joint fusion.
• Varisync Stand-Alone ALIF System Integrated lumbar spacer with plate, cage, and fixation for ALIF procedures, offering NanoPrime IBF or F3D-Z cages with anchor and/or screw fixation options for spine surgeons treating anterior lumbar pathologies.
• eZspand Expandable Interbody System Expandable titanium interbody device for customizable disc height restoration and fusion, offering up to 4.5mm of continuous cage height expansion without a secondary locking step, with a large graft window through the device.
• ZMI-90 Cement Mixing & Injection System All-in-one cement mixing and injection system that delivers consistent cement mixing in under 90 seconds with single-button operation for vertebral augmentation procedures.
• Normandy Cervical VBR System Expandable corpectomy cage offering adjustable-height vertebral body replacement with six height range options for cervical corpectomy procedures requiring surgical versatility.
• Normandy Thoracolumbar VBR System Adjustable-height vertebral body replacement device for restoring stability after corpectomy or vertebrectomy in the thoracolumbar spine, with five height range options.
• F3D Lateral Interbody System Lateral interbody cages leveraging Mimetic Metal technology, with a unique trapezoidal footprint for precise anatomical fit and large graft windows for bone-graft packing in LLIF procedures.
• CL5 Lateral Interbody System Lateral interbodies offering a wide range of size and lordosis options, designed with elegant instrumentation to address varied patient anatomies and surgeon preferences in LLIF procedures.
• Oro Lateral Plate System Low-profile lateral lumbar plating system with an automatic locking mechanism to prevent screw back-out, designed as an adjunct to lateral fusion and compatible with CL5 and F3D lateral interbodies.
• Vantage Lateral Retractor Lateral access retractor with two- or three-blade constructs optimized for a balance of radiolucency, rigidity, and minimized psoas disruption during LLIF procedures.
• ZVplasty Kits Vertebral compression fracture treatment kits combining kyphoplasty access tools, balloon catheters, and cement delivery components for vertebral augmentation procedures.
• ZVplasty Balloons Variety of balloon types for vertebral augmentation, including 10 and 11 gauge options, flex balloons for unipedicular access, and curve-plus balloons for kyphoplasty cavity creation.
• Entasis SI Joint Fusion System Lateral sacroiliac joint fixation solution with self-harvesting fenestrations, dual-lead threads, and an adjustable-length guide wire for SI joint fusion procedures.
• SInapse SI Joint Fusion System Self-tapping and self-drilling SI joint screw with a patented cutting tip, designed for the posterior oblique approach to sacroiliac joint fusion.
• Tiger 2 X-Tab MIS Pedicle Screw System Minimally invasive fixation solution designed to minimize operative steps, with extended tabs for quick implantation and integrated reduction threads for thoracolumbar MIS procedures.
• Unifuze-C Collagen Strips High-quality collagen matrix made of bovine-derived collagen for cellular attachment and support, designed to be saturated with patient whole blood as a fusion adjunct.
• Unifuze-P Synthetic Putty Preloaded synthetic putty for advanced healing, with putty-like consistency for precise placement, biocompatible and resorbable, with osteoconductive properties for spinal fusion.
• Amnion Patch Multi-layer amniotic tissue allograft providing a protective barrier, cell scaffold, and natural source of cytokines and growth factors as a biologic adjunct in spine surgery.
• Centrafix Midline Fixation System Posterior thoracolumbar pedicle screw system designed for a midline approach with medial-to-lateral cortical bone trajectory for spine surgeons using cortical bone trajectory fixation.
• Z-Span Expandable Plate System Expandable titanium lateral plate designed for lateral spinal stabilization and immobilization as an adjunct to fusion in LLIF procedures.
• Anodyne Anterior Cervical Plate System ACDF plating solution featuring a positive-stop locking mechanism and variable screws providing an 18-degree range of sagittal angulation for cervical fusion procedures.
• ChoiceSpine Spinal Implant Systems Spinal implant systems spanning cervical, thoracolumbar, and interbody applications acquired in February 2026 and operating under the retained ChoiceSpine brand; designs and manufactures spinal implant systems for surgeons and hospitals.

Segments3 records

Ideal customer profiles2 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature5 records

Partnerships

Three partnerships are on record, tiered core and minor.

• ChoiceSpine HoldingscoreOthers · 26 February 2026Zavation acquired ChoiceSpine Holdings, a designer and manufacturer of spinal implant systems based in Knoxville, Tennessee, founded in 2006. The acquisition expands Zavation's product portfolio and commercial reach across inpatient and outpatient settings. ChoiceSpine maintains its brand and operations while integrating with Zavation's vertically integrated manufacturing platform.
• CoreLinkcoreOthers · 26 June 2023Zavation acquired CoreLink, a spinal implant and instrumentation systems company previously owned by The Stephens Group, LLC. The acquisition expanded Zavation's portfolio in the spinal healthcare market and was part of strategic expansion in the medical device sector.
• PanMedicalminorOthers · 1 January 2016Zavation acquired PanMedical and expanded kyphoplasty offerings, broadening the company's interventional spine product portfolio.

Scale indicators5 records

Recent moves9 records

Expansion highlights5 records

Direct peers

• Globus Medical: One of the largest pure-play spine device companies, competing head-to-head with Zavation across cervical, thoracolumbar, interbody, and MIS fusion technologies. Direct comparable given the same surgeon call point and overlapping product portfolio.
• Orthofix Medical: Spinal implant and biologics company with cervical, thoracolumbar, and interbody products. Directly comparable given similar scale, distributor-driven model, and overlapping product breadth competing for the same surgeon accounts.
• Alphatec Spine: Independent spine company focused on surgical approach-driven differentiation (ALIF, LLIF, MIS). Direct peer given the same mid-size spinal implant positioning, aggressive product launch cadence, and similar surgeon-customer profile.
• SI-BONE: Pure-play sacroiliac joint fusion company whose iFuse and related products directly overlap with Zavation's Siber Ti, Entasis, and SInapse SI joint fusion systems. Relevant given Zavation's stated focus on sacroiliac procedures.
• Xtant Medical: Spinal implant and biologics company competing with Zavation's interbody and fusion portfolio. Comparable on small-mid size, biologics attach, and similarly themed product positioning across spine.

Broad incumbents

• Stryker (Spine division): Stryker's spine and biologics franchise competes with Zavation across many of the same procedure categories. Comparable because they overlap on spinal implants but Stryker operates across many other med-surg segments, making it a broader incumbent rather than a focused peer.
• Medtronic (Spine & Biologics): Medtronic's Spine & Biologics business competes across the same fusion, interbody, and procedural categories that Zavation addresses. It is a broad incumbent due to its size and diversified portfolio, but overlaps materially on core spine procedures.
• NuVasive: Specialty spine company with deep MIS, lateral, and cervical portfolios competing across Zavation's procedural footprint. Broad incumbent comparable because it serves the same surgeon call point and overlaps on most of Zavation's procedure categories.

Emerging players

• Captiva Spine: Privately held spine company developing novel cervical and sacroiliac technologies. Comparable as a small, niche player working through independent distributors similar to Zavation, often competing for similar accounts.
• Pacifica Spine: Emerging spine company focused on MIS and motion-preserving technologies. Relevant as a niche, innovation-driven player with comparable targeted product releases competing for the same MIS-focused surgeons.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat4 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/zavation
• YouTubeyoutube.com/@ZavationMedicalProductsLLC
• Facebookfacebook.com/zavation
• LinkedInlinkedin.com/company/zavationllc
• Instagraminstagram.com/zavationllc

Compliance4 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles7 records

Subsidiaries1 record

Funding overview

Funding rounds1 record

Investors1 record

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A3 records

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Zavation