Millennium Health

What Millennium Health does

Millennium Health is an accredited specialty clinical laboratory providing definitive drug testing services to healthcare providers across the United States. The company's core offerings are Millennium UDT (urine drug testing) and Millennium OFT (oral fluid drug testing), both utilizing liquid chromatography-tandem mass spectrometry (LC-MS/MS) methodology to detect more than 100 drugs and metabolites encompassing over 400 brand-name drugs. Testing is supported by the proprietary Intellium platform for test management and the RADAR reporting system, which delivers results within one business day with toxicologist consultation. The company is CAP-accredited, CLIA-certified for high-complexity testing, and holds HITRUST certification for the Intellium platform.

Millennium Health processes over one million specimens annually and has built a proprietary database of millions of clinical urine drug test results spanning all 50 states. This data asset underpins the Signals Report series (published since 2019), the Signals Alert emerging-threat notifications, and the Emerging Threat Intelligence (ETI) Program. The company publishes peer-reviewed studies in journals including JAMA Network Open, JAMA Psychiatry, Drug and Alcohol Dependence, and Journal of Opioid Management, and collaborates with the CDC, HHS, Ohio Department of Public Safety, Columbia University, and multiple academic medical centers.

The go-to-market model is direct enterprise field sales to prescribers in substance use disorder treatment, pain management, behavioral health, primary care, addiction treatment, obstetrics and gynecology, and multi-specialty group practices. Revenue is generated through fee-for-service laboratory testing billed to commercial payers (including UnitedHealthcare under a six-year Preferred Lab Network relationship), government programs, and patients. The company is privately held under the legal entity Millennium Health LLC, headquartered in San Diego, California, with CEO Scott Walton leading the organization since October 2021.

Name

Millennium Health

Legal name

Millennium Health LLC

Website

https://millenniumhealth.com

Company type

Private

Founded year

2010

Operating status

Operating

Headcount range

1,001–5,000 employees

Short description

Millennium Health is an accredited specialty clinical laboratory providing LC-MS/MS urine and oral fluid drug testing to healthcare providers across all 50 U.S. states, processing over one million specimens annually and publishing the proprietary Signals Report on drug use trends.

Ownership category

akta.pro rank

Product category

Clinical Laboratory Services

NAICS

Medical Laboratories (621511)

SIC

Services-Medical Laboratories (8071)

akta.pro primary industry

Toxicology & Therapeutic Drug Monitoring Laboratories (HLAFAMAF)

akta.pro secondary industries

SaMD – Digital Biomarkers & Algorithmic Endpoints (HLACANAF), DMPK / ADME & Bioanalysis (HLAGAFAC)

Keywords

• Urine drug testing
• Oral fluid drug testing
• Clinical laboratory services
• Medication monitoring
• Substance use disorder testing

Headquarters

HQ city

San Diego

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Operations, Technology or R&D, Marketing or Sales, Infrastructure

Revenue model

1. Clinical Drug Testing Services: Fee-for-service laboratory testing for urine drug testing (UDT) and oral fluid drug testing (OFT) provided to healthcare providers across multiple specialties including substance use disorder treatment, pain management, behavioral health, and primary care. Services billed to payers including commercial insurance, government programs, and patients directly.

Go-to-market motion2 records

Distribution channels1 record

Marketing channels5 records

Core offering

Millennium Health is an accredited specialty clinical laboratory that provides definitive urine drug testing (UDT) and oral fluid drug testing (OFT) using LC-MS/MS methodology to detect over 100 drugs and metabolites. Its services support clinicians in substance use disorder treatment, pain management, and behavioral health, and are delivered alongside the proprietary Intellium data platform and national drug use trend analytics.

Product overview

Millennium Health is an accredited specialty laboratory offering a comprehensive drug testing portfolio centered on two core testing services: Millennium UDT (urine drug testing) for definitive detection of 100+ drugs/metabolites across 400+ brand names, and Millennium OFT (oral fluid drug testing) as a convenient alternative. These core services are supported by the Intellium platform, which provides test management, data intelligence, and the RADAR reporting system with results delivered within one business day. The company also produces analytical intelligence products including the Signals Report (comprehensive national drug use trend analysis) and Signals Alert (timely emerging threat notifications). The portfolio is unified by a commitment to processing over a million specimens annually, enabling real-time analytics and collaboration with public health agencies including the CDC and HHS.

Differentiator

Problem solved

Functional benefit

Brands

• Millennium UDT: Urine drug testing services allowing definitive detection of more than 100 drugs and metabolites.
• Millennium OFT
• Intellium
• RADAR Report
• Continuum

Products and services

• Millennium UDT (Urine Drug Testing) Definitive urine drug testing service using LC-MS/MS methodology that detects over 100 drugs and metabolites, offered to clinicians for substance use disorder treatment, pain management, and behavioral health decision support.
• Millennium OFT (Oral Fluid Drug Testing) Definitive oral fluid drug testing service using LC-MS/MS methodology to detect over 100 drugs and metabolites, providing an alternative specimen type for clinicians needing rapid or observed collection.
• Continuum Service program offered by Millennium Health to support clinicians in managing patients through definitive drug testing and clinical reporting.
• Intellium Proprietary data intelligence and reporting platform that provides test management, data intelligence, and reporting for Millennium Health's drug testing services, including RADAR reporting for clinicians.
• Millennium Health Signals Report National drug use trend analytics program that aggregates testing data across the United States to report on drug use patterns by region, drug class, and age group.
• Signals Alert Alert product associated with the Signals Report program that notifies clinicians and stakeholders about emerging drug use trends or threats identified through Millennium Health's national testing data.
• Emerging Threat Intelligence (ETI) Program Intelligence program offered by Millennium Health that monitors and reports on emerging substance use threats, supporting clinicians, treatment programs, and public health stakeholders with early warning insights.

Quantifiable outcome

• 85% of people testing positive for fentanyl in 2025 also tested positive for stimulants, with cocaine and methamphetamine detections exceeding heroin and prescription opioids in every U.S. state for the first time
• +5 more outcomes

Named customers4 records

Segments1 record

Ideal customer profiles1 record

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature6 records

Partnerships

Eight partnerships are on record, tiered core and minor.

• UnitedHealthcarecoreChannel Partner/ Reseller/ Distributor · 6 November 2025Selected for UnitedHealthcare Preferred Lab Network for the sixth consecutive year, aligning with UHC's Triple Aim Focus on improving healthcare affordability, outcomes, and patient experience.
• Centers for Disease Control and Prevention (CDC)coreStrategic or Co-development Partner · 7 February 2023Multi-year contract where Millennium Health provides real-time urine drug testing data and analytics to CDC to support efforts to save lives and prevent fatal drug overdoses. CDC collaboration also includes clinical drug test dashboard for timely insights on shifting drug use trends.
• Penn State College of MedicineminorStrategic or Co-development Partner · 13 September 2022Collaborative research at PAINWeek conference regarding illicit drug use among people with chronic pain, demonstrating urine specimens from pain management practices testing positive for heroin, illicit fentanyl, cocaine, and methamphetamine.
• Ohio State University College of MedicinecoreStrategic or Co-development Partner · 8 June 2022JAMA Network Open study demonstrating strong correlation between urine drug test results and drug overdose deaths, presenting new opportunity in fight against substance use crisis.
• University of CincinnaticoreStrategic or Co-development Partner · 10 May 2022NIDA-funded research collaboration to investigate precipitated withdrawal during buprenorphine induction, addressing treatment challenges for opioid use disorder.
• Columbia UniversitycoreStrategic or Co-development Partner · 31 August 2021Agreement to provide real-time drug use trends data through Emerging Threat Intelligence Program to aid Columbia's HEALing Communities Study efforts in New York to combat overdoses.
• Ohio Department of Public SafetycoreStrategic or Co-development Partner · 9 September 2020First state in the country to utilize Millennium Health's real-time drug use trends data to combat overdoses. Agreement provides real-time data to help direct public health responses to the substance use crisis.
• U.S. Department of Health and Human Services (HHS)coreStrategic or Co-development Partner · 7 January 2020Agreement to provide real-time data to HHS as an aid in rapidly directing public health responses to the constantly evolving substance use epidemic. Includes co-authored JAMA study on drug use trends.

Scale indicators8 records

Recent moves7 records

Expansion highlights6 records

Direct peers

• Aegis Sciences Corporation: Aegis is the closest direct competitor to Millennium — a Nashville-based specialty clinical toxicology laboratory offering definitive urine drug testing using LC-MS/MS to pain management, behavioral health, and addiction treatment providers nationwide. Comparable business model, customer base, and test methodology.
• Cordant Health Solutions: Cordant is a specialty toxicology laboratory providing medication monitoring and drug testing services to addiction treatment, pain management, and behavioral health providers. Direct overlap with Millennium in UDT, oral fluid testing, and clinical decision support tools.
• United States Drug Testing Laboratories (USDTL): USDTL is a specialty laboratory focused on substance use disorder testing, including definitive drug and alcohol testing using LC-MS/MS. Targets similar clinical segments including addiction treatment and pain management, competing head-to-head in UDT.
• Dominion Diagnostics: Dominion is a clinical laboratory specializing in urine drug testing and medication monitoring for substance use disorder and pain management. Provides comparable definitive LC-MS/MS testing services to a similar clinician customer base.
• Clinical Reference Laboratory (CRL): CRL is a privately held clinical reference laboratory offering specialized toxicology and clinical drug testing services. Provides comparable UDT and medication monitoring to healthcare providers.
• Precision Toxicology: Precision Toxicology is a specialty clinical laboratory providing urine drug confirmation and pain management toxicology testing using LC-MS/MS. Competes in the same clinical drug testing category with a similar customer base.
• Pacific Toxicology Laboratories: Pacific Toxicology is a CLIA-certified specialty laboratory offering clinical and forensic drug testing services. Provides urine drug testing with comparable methodology to Millennium's clinical clientele.

Broad incumbents

• Quest Diagnostics: Quest is a national reference laboratory offering toxicology and drug testing as part of a broad menu. While Millennium's specialty focus differs from Quest's generalist model, Quest competes for the same clinical drug testing orders from healthcare providers.
• Laboratory Corporation of America (LabCorp): LabCorp is a national clinical laboratory network that includes drug testing and toxicology services in its broad menu. Competes for healthcare provider drug testing volume alongside its wider diagnostic offerings.
• Eurofins Scientific: Eurofins is a global laboratory services group with clinical diagnostics and toxicology testing capabilities in the U.S. market. While much broader than Millennium, Eurofins competes for clinical drug testing volume through its clinical diagnostics network.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks5 records

Key highlights7 records

Customer concentration

• Xx.com/millenniumhlth
• YouTubeyoutube.com/channel/UCb9R-TDmgAJQMYddftvM83w
• Facebookfacebook.com/millenniumhlth
• LinkedInlinkedin.com/company/millennium-health
• Instagraminstagram.com/millenniumhealth

Compliance3 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles6 records

Funding overview

Funding rounds1 record

Investors1 record

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Millennium Health