What Zymox does

Zymox is a pet health care brand operated by Pet King Brands LLC (also referenced as PKB Animal Health, Inc.), a privately held, founder-owned company headquartered in Austin, Texas with a shipping center in Illinois. Founded around 1999, the company has built a 25+ year franchise around proprietary enzyme-based formulations — specifically the LP3 Enzyme System, Antibiofilm Enzyme System, and LP3 + MD2 Enzyme Systems — used in over-the-counter ear, skin, and oral care products positioned as antibiotic-free alternatives for dogs, cats, birds, reptiles, small animals, and equines. The product portfolio includes enzymatic otic solutions (with and without hydrocortisone), ear wipes, dermatology/skin care products, the Oratene brushless oral care line, Funky Paws dog dental products, the Equine Defense line, the Cage Diaper specialty item, and an expanded veterinary line announced for 2025.

The business model is multi-channel consumer packaged goods (CPG) distribution combined with professional channel sales. Products are sold direct-to-consumer through zymox.com at unit prices ranging from $16.99 to $33.49, and through online retailers (Chewy.com, Amazon), pet specialty retail chains, veterinary clinics, grooming professionals, agricultural/farm retail (Orscheln Farm & Home), military commissaries worldwide, and a 2025 wholesale partnership with Pet Palette Distribution. International reach is via third-party distributors rather than owned infrastructure. Marketing combines trade show presence (SuperZoo, Global Pet Expo, VMX, WVC, Groom Expo), veterinary professional education (lecture series, webinars on otitis externa), an affiliate program, content marketing, and event sponsorships (Westminster Kennel Club Dog Show, Super Pet Expo, Cat Fanciers Association, AZA). The company has accumulated multiple industry awards including Vanguard Awards (2024, 2025), Pet Age Editor's Select (2025, 2026 across bird/dog/reptile/small animal categories), Pet Age Power 50 (2024), Best in Show at Global Pet Expo (2023), and a Pet Product News Editors' Choice Award (2024).

Name

Zymox

Legal name

Pet King Brands LLC

Website

https://zymox.com

Company type

Private

Founded year

1999

Operating status

Operating

Headcount range

11–50 employees

Short description

Zymox, a brand of privately held Pet King Brands LLC, sells proprietary enzyme-based, antibiotic-free ear, skin, and oral care products for dogs, cats, birds, reptiles, small animals, and equines through DTC, major online retailers, pet specialty stores, vet clinics, and groomers.

Ownership category

akta.pro rank

Product category

Pet Health Care Products

NAICS

Pet and Pet Supplies Retailers (45991), Biological Product (except Diagnostic) Manufacturing (325414)

SIC

Biological Products, (No Disgnostic Substances) (2836), Pharmaceutical Preparations (2834), Perfumes, Cosmetics & Other Toilet Preparations (2844)

akta.pro primary industry

Dermatology & Allergy Drugs (HLAMAEAH)

akta.pro secondary industries

Animal Health OTC Retail (Parasite Control, Basic Care) (HLAMAIAJ), Biologics & Immunotherapies (Non-vaccine) (HLAMAEAK), Allergy & Anti-Inflammatory Supplements (HLAMALAL), Immune Support Supplements (HLAMALAE)

Keywords

• Enzymatic pet care
• Pet ear care
• Pet dermatology
• Brushless oral care
• Pet health products

Headquarters

HQ city

Westmont

HQ country

United States

HQ region

North America

Offices2 records

Markets served

GTM type

B2C

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Marketing or Sales, Personnel, Operations, Technology or R&D, Infrastructure

Revenue model

1. Direct Product Sales (B2C): Direct-to-consumer sales of ZYMOX enzymatic pet care products (ear care, skin care, oral care) through zymox.com e-commerce platform. Products sold as one-time purchases with pricing ranging from $16.99 to $33.49 for standard sizes.
2. Wholesale/Retail Distribution (B2B): Wholesale distribution through pet specialty retailers, online retailers (Chewy, Amazon), veterinary clinics, grooming professionals, and agricultural/farm stores (Orscheln Farm & Home). Products also available through military commissaries worldwide.
3. Distributor/Franchise Model: Nationwide distribution through distribution partners like Pet Palette Distribution and international distributors. Products distributed through authorized seller network.

Pricing tiers

Go-to-market motion3 records

Distribution channels8 records

Marketing channels8 records

Core offering

Zymox manufactures and sells a line of over-the-counter, antibiotic-free enzymatic pet health care products for dogs, cats, birds, reptiles, small animals, and horses. The portfolio spans ear care (otic solutions with hydrocortisone variants and ear wipes), skin/dermatology care (topical solutions for hot spots, itchy and irritated skin), and brushless oral care (Oratene line), with specialty lines including Equine Defense, Cage Diaper for birds, Funky Paws, and avian/reptile/small animal products. All formulations are built on the company's proprietary LP3 Enzyme System and supporting enzyme complexes.

Product overview

ZYMOX is a portfolio of enzymatic pet health care products manufactured by PKB Animal Health (Pet King Brands), featuring a proprietary LP3 Enzyme System for antibiotic-free ear, skin, and oral care. The product line spans multiple categories including ear care solutions (otic solutions with varying hydrocortisone levels, ear wipes), dermatology/skin care products, and oral care through the Oratene sub-brand. Products are USA-made and target multiple pet types including dogs, cats, birds, reptiles, small animals, and horses. The company also offers equine-specific products under Equine Defense and specialty items like Cage Diaper for birds. The LP3 Enzyme System and related enzyme technologies (Antibiofilm, MD2) form the core technological foundation enabling the product portfolio.

Differentiator

Problem solved

Functional benefit

Brands

• LP3 Enzyme System: The proprietary enzyme system used in ZYMOX products, providing gentle yet effective enzyme-powered solutions for pets' skin, ears, and oral health.
• Oratene Brushless Oral Care
• ZYMOX Enzymatic
• ZYMOX Funky Paws

Products and services

• ZYMOX Advanced Formula Otic Plus with 1% Hydrocortisone Enzymatic ear solution for dogs and cats containing 1% hydrocortisone, used to relieve ear infections and inflammation; sold over the counter as a 1.25oz bottle for at-home ear care.
• ZYMOX Enzymatic Ear Solution with 0.5% Hydrocortisone for Cats & Kittens Gentle enzymatic ear solution specifically formulated for cats and kittens, with 0.5% hydrocortisone, sold as a 1.25oz bottle for at-home feline ear care.
• ZYMOX Advanced Enzymatic Ear Wipes Pre-moistened enzymatic ear wipes for convenient daily ear cleaning in dogs and cats, packaged in a jar format.
• ZYMOX Otic Enzymatic Solution with 1% Hydrocortisone USA-made otic enzymatic solution with 1% hydrocortisone, sold as a 1.25oz bottle for dogs and cats needing over-the-counter ear care.
• Oratene Brushless Oral Care Brushless oral care product line for dogs and cats that provides dental hygiene and fresh breath without brushing, using LP3 + MD2 enzyme technology.
• ZYMOX Funky Paws Dedicated dog oral and dental care product line within the ZYMOX portfolio, featuring the company's enzymatic technology.
• ZYMOX Equine Defense Enzymatic dermatology products formulated for horses, addressing chronic hide and hoof conditions.
• ZYMOX Cage Diaper Cage diaper products designed for birds and small animals, sold under the ZYMOX brand.
• ZYMOX Avian Care Line Enzymatic pet health care products specifically formulated for birds and avian pets.
• ZYMOX Small Animal & Exotic Line Enzymatic pet health care products designed for small animals, reptiles, and exotic pets, addressing ear, skin, and oral care needs.
• ZYLAFEN Topical Solution Topical solution product within the ZYMOX dermatology line, addressing skin-related conditions in pets.

Quantifiable outcome

• Enzyme-based formulas shown to be beneficial for otitis externa management

Named customers3 records

Segments7 records

Ideal customer profiles4 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature3 records

Partnerships

Ten partnerships are on record, tiered core and minor.

• Super Pet ExpocoreGTM or Marketing Partner · 19 December 2025ZYMOX became a new sponsor for Super Pet Expo's 25th Anniversary celebration, supporting the premier pet industry expo event.
• Pet Palette DistributioncoreChannel Partner/ Reseller/ Distributor · 1 March 2025Pet Palette Distribution partners with Pet King Brands to distribute ZYMOX products nationwide. This distribution partnership expands retail availability across the United States.
• Shelters UnitedcoreStrategic or Co-development Partner · 1 January 2025Pet King Brands announced partnership with Shelters United to support shelter animals and pet adoption initiatives. Partnership focuses on providing pet health products to shelters and promoting animal welfare.
• Westminster Kennel Club Dog ShowcoreGTM or Marketing Partner · 1 January 2025ZYMOX joined the 149th Annual Westminster Kennel Club Dog Show as new sponsor, offering trusted pet health solutions at this prestigious dog show event.
• Retail.PetminorChannel Partner/ Reseller/ Distributor · 1 September 2024ZYMOX joined Retail.Pet platform for enhanced retail partnership and distribution opportunities.
• Association of Zoos & Aquariums (AZA)coreStrategic or Co-development Partner · 1 January 2024Pet King Brands joined AZA, demonstrating commitment to zoo and aquarium animal health and wellness programs.
• Cat Fanciers AssociationminorGTM or Marketing Partner · 1 January 2024ZYMOX sponsors Cat Fanciers Association virtual cat shows and 2020 Top Cat Challenge, as well as TrapKing's TNR fundraising cat photo contest.
• General Pet SupplyminorChannel Partner/ Reseller/ Distributor · 1 January 2021ZYMOX Dermatology and Oratene Brushless Oral Care products made available through General Pet Supply distribution.
• Orscheln Farm & HomecoreChannel Partner/ Reseller/ Distributor · 1 September 2020Pet King Brands partnered with Orscheln Farm & Home to offer ZYMOX pet health care products at their farm and home retail locations.
• Military CommissariesminorChannel Partner/ Reseller/ Distributor · 1 January 2020ZYMOX dermatology products available at military commissaries around the world, serving military members and their pets.

Scale indicators4 records

Recent moves7 records

Expansion highlights6 records

Broad incumbents

• Vetoquinol: Animal health company with dermatology, ear care, and oral hygiene product lines for dogs and cats. Comparable to Zymox in OTC and Rx pet dermatology and otic categories, with established global distribution.
• Virbac: Global animal health pharmaceutical company with a portfolio spanning dermatology, ear care, and oral care for companion animals. Directly comparable to Zymox in the otic and dermatology OTC/Rx categories, but with a much broader portfolio and global commercial reach.
• Elanco Animal Health: One of the largest global animal health companies offering a broad portfolio including dermatology and pet care products. Comparable to Zymox as a broad incumbent with overlapping dermatology and ear care capabilities, though serving a much wider therapeutic and livestock footprint.
• Dechra Pharmaceuticals: Specialty animal health company focused on companion animal therapeutics including dermatology and otic products. Comparable to Zymox in the dermatology and ear care categories but with a stronger pharmaceutical and prescription product portfolio.
• Zoetis: World's largest animal health company with dermatology, otic, and oral care products across companion animals. Comparable to Zymox as the dominant broad incumbent in the animal health space with overlapping product categories and far greater scale and R&D resources.
• Bayer Animal Health (Elanco-acquired): Formerly Bayer Animal Health, now part of Elanco, with historical OTC pet care brands including dermatology products. Comparable to Zymox in the OTC pet dermatology and ear care categories through legacy brands.
• Ceva Santé Animale: Global animal health company with companion animal dermatology, behavior, and care products. Comparable to Zymox in the dermatology and ear care categories, particularly for dogs and cats, with broader geographic reach.

Direct peers

• PetHonesty: DTC-focused pet health and supplement company offering skin, allergy, dental, and wellness products for dogs and cats. Comparable to Zymox as a direct peer in OTC pet wellness with similar distribution through Chewy and Amazon, though emphasizing supplements versus enzymes.
• Vet's Best (now under Elanco): OTC pet wellness brand offering ear care, skin care, and dental products using natural ingredients. Comparable to Zymox as a direct peer in OTC pet ear and skin care at similar retail price points, now part of Elanco's pet care portfolio.
• Nutri-Vet: OTC pet health products company offering ear care, skin care, and wellness products for dogs and cats. Closely comparable to Zymox as a direct peer in OTC pet care, distributed through similar retail and vet channels at comparable price points.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat4 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/ZymoxOfficial
• Facebookfacebook.com/ZymoxProducts
• LinkedInlinkedin.com/company/pkb-pet-king-brands

Revenue estimate

Valuation estimate

Number of profiles

Profiles6 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Zymox