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EMBL

Full company profile

uuid0009bqz

Namestring
EMBL
Legal namestring
European Molecular Biology Laboratory
Websiteurl
embl.org
Company typeenum
Private
Founded yearint
1974
Descriptiontext

The European Molecular Biology Laboratory (EMBL) is an intergovernmental research organization founded in 1974 and headquartered in Heidelberg, Germany, operating Europe's flagship life sciences laboratory across six sites: Heidelberg, Barcelona, Grenoble, Hamburg, Hinxton (EMBL-EBI), and Rome. EMBL performs fundamental molecular biology research spanning structural biology, computational biology, epigenetics, neurobiology, and infection biology, and delivers services through specialized facilities including synchrotron beamlines, the EMBL Imaging Centre, and the world's primary open-access bioinformatics data resources.

EMBL's core product surface consists of open-access data platforms — the Ensembl genome browser covering 5,000+ species and the AlphaFold Protein Structure Database with 1.7 million predicted protein complexes, delivered in partnership with Google DeepMind and NVIDIA — alongside scientific instrumentation including the EasyGrid cryo-EM automation system and BSxCuBE-Web BioSAXS interface. EMBL-EBI provides programmatic data access via a new GraphQL API and refget protocol. The organization also operates an international PhD programme and an EMBL Events platform hosting 50+ annual courses, conferences, and workshops covering synthetic biology, cryo-EM, bioinformatics, and proteomics.

EMBL's business model is primarily member-state government funding rather than commercial revenue, supplemented by fee-based training (500-1,100 EUR per participant for in-person events, 190-290 EUR for virtual) and industry sponsorship. The organization serves academic researchers, PhD students, and early career scientists as primary users, with industry researchers and corporate partners (Leica Microsystems, NVIDIA, DeepMind) as a secondary segment. Technology transfer is beginning via a new spin-off vehicle for EasyGrid commercialization, indicating a nascent revenue diversification beyond grant funding.

Short descriptiontext

The European Molecular Biology Laboratory is an intergovernmental life sciences research organization founded in 1974, operating across six European sites and serving academic researchers, PhD students, and industry with open-access bioinformatics data resources, advanced training, and specialized research facilities.

Operating statusenum
Operating
Ownership categoryenum
Headcount rangeband
1,001–5,000
akta.pro rankint
HeadquartersHeidelberg, Germany
HQ citystring
Heidelberg
HQ countrystring
Germany
HQ regionstring
Europe
Markets served

Serves global market

Offices6 records

Each record includes

City, Country, Type, Description, Source

Keyword5 values
molecular biology research, bioinformatics data resources, structural biology services, scientific training programs, life sciences research
Industry2 codes
1Knowledge Management & Scientific Collaboration / Literature Intelligence
CodeHLAGAJANPrimaryYes
2Transcriptomics & Gene Expression Profiling Services
CodeHLAGANAEPrimaryNo
NAICS code4 codes
  • Research and Development in Biotechnology (except Nanobiotechnology)541714
  • Research and Development in the Physical, Engineering, and Life Sciences54171
  • Colleges, Universities, and Professional Schools611310
  • Professional and Management Development Training61143
SIC code2 codes
  • Services-Commercial Physical & Biological Research8731
  • Services-Educational Services8200
Product category
Life Sciences Research
Social media profiles2 records
Marketing channels4 records

Each record includes

Title, Type, Stage, Description, Source

Distribution channels4 records

Each record includes

Title, Type, Scope, Target buyer, Description, Source

Cost components6 values
Personnel, Operations, Technology or R&D, Infrastructure, Marketing or Sales, Others
Pricing details4 tiers
1Academic/Researcher registration fee
ModelSubscriptionBilling cadenceOne time/ perpetual license
Notes

500-550 EUR per participant for academic/researchers attending courses and conferences

embl.org
2PhD Student registration fee
ModelSubscriptionBilling cadenceOne time/ perpetual license
Notes

500-550 EUR per participant for PhD students, with travel grants available up to 500-1000 EUR

embl.org
3Industry registration fee
ModelSubscriptionBilling cadenceOne time/ perpetual license
Notes

1050-1100 EUR per participant for industry attendees

embl.org
4Virtual Conference Registration
ModelSubscriptionBilling cadenceOne time/ perpetual license
Notes

190-290 EUR for virtual attendance at conferences

embl.org
GTM typeB2B
B2B
Offering typeServices
Services
Brand1 record
1EMBL-EBI
Description

European Bioinformatics Institute - provides open data resources that enable discovery, and performs research in computational biology

embl.org
Core offering1 text field

EMBL is an intergovernmental life sciences research organization that performs fundamental molecular biology research and delivers scientific services across six European sites. It provides open-access bioinformatics data resources (Ensembl, AlphaFold Protein Structure Database), develops novel scientific instrumentation (EasyGrid cryo-EM, BSxCuBE-Web), and offers specialized training programs, courses, and conferences through its Advanced Training Centre. The organization serves academic researchers, PhD students, and industry researchers worldwide through its facilities, data resources, and educational offerings.

Differentiator
Functional benefit
Problem solved
Quantifiable outcome1 of 3 values shown
  • Sevenfold improvement in vitrification quality for cryo-EM sample preparation compared to traditional methods
+2 more records
Product overview1 text field

EMBL (European Molecular Biology Laboratory) is Europe's life sciences laboratory operating across six sites (Barcelona, Grenoble, Hamburg, Heidelberg, Hinxton/EMBL-EBI, Rome). The organization provides a suite of research products and services including: the Ensembl genome browser offering free genome annotation for over 5000 species with new GraphQL API access; the AlphaFold Protein Structure Database (with 1.7M predicted protein complexes) in partnership with Google DeepMind and NVIDIA; the EasyGrid cryo-EM automation system; BSxCuBE-Web for automated BioSAXS experiments; and EMBL Events providing courses, conferences, and workshops. EMBL-EBI provides open data resources and computational biology research, while the EMBL Imaging Centre offers advanced microscopy services. Services are delivered through an events platform with both virtual and on-site participation options.

Product and service1 record
1Ensembl Genome Browser
Scale indicator7 records

Each record includes

Type, Value, Description, Source

Partnership7 partners
Strategic tierCoreTypeStrategic or Co-development Partner
Description

NVIDIA partnership for AI infrastructure in life sciences, including expansion of the AlphaFold Protein Structure Database with Google DeepMind and EMBL, adding 1.7 million predicted protein complexes. NVIDIA GTC 2026 featured announcements around this collaboration in healthcare, robotics, and drug discovery.

Strategic tierCoreTypeStrategic or Co-development Partner
Description

Collaborative research partnership with EMBL Heidelberg and Mi-EOCRC consortium for microbiome study analyzing 6,799 gut microbiome profiles from 27 studies, identifying robust colorectal cancer microbiome signature.

Strategic tierCoreTypeStrategic or Co-development Partner
Description

Collaboration with ESRF beamline BM29 for BioSAXS experiments, where EMBL Grenoble developed BSxCuBE-Web interface to automate high-throughput BioSAXS experiments.

Strategic tierCoreTypeStrategic or Co-development Partner
Description

Joint funding and organization of courses and conferences. EMBO and EMBL jointly fund symposia promoting scientific communication and collaboration in the European research area.

Strategic tierCoreTypeStrategic or Co-development Partner
Description

Cooperation for STED nanoscopy course, with Leica providing expert faculty and technology demonstrations. Course organized in cooperation with Leica Microsystems CMS GmbH.

Strategic tierCoreTypeStrategic or Co-development Partner
Description

Partnership for AlphaFold Protein Structure Database expansion, adding 1.7 million predicted protein complexes accessible to the global scientific community.

7EMBL Advanced Training Centre Corporate Partnership Programme
Strategic tierMinorTypeGTM or Marketing Partner
Description

Corporate partnership program providing financial assistance for training courses in the form of travel grants, childcare grants, and registration fee waivers.

embl.org
Recent move7 records

Each record includes

Date, Type, Title, Description, Source

Expansion highlight5 records

Each record includes

Type, Description

Peers10 records
TypeDirect peer
Description

US-based biomedical and genomic research institute operating at comparable scale in molecular biology, genomics, and computational biology. Most direct analogue to EMBL's pan-disciplinary research-and-data model, including flagship data resources analogous to Ensembl.

TypeDirect peer
Description

UK-based genomic and bioinformatics research institute with comparable focus on large-scale molecular biology, genome annotation, and open data resources. Closely comparable to EMBL-EBI in mission and outputs.

TypeDirect peer
Description

London-based biomedical research institute with multi-disciplinary molecular biology programs and significant training activity. Comparable as a European, government-and-philanthropy funded research organization serving a similar scientific audience.

TypeBroad incumbent
Description

Large US biomedical research organization supporting Investigator-led labs across many institutions. Comparable as a sustainable, mission-driven funder of fundamental life-science research with strong training and open-science commitments.

TypeBroad incumbent
Description

German government-funded research society operating numerous institutes in life sciences and beyond. Comparable in scale, public funding model, and training mission; complementary geographically (Germany-based, like EMBL Heidelberg).

TypeBroad incumbent
Description

France's largest government-funded research organization covering life sciences and beyond. Comparable as a public, multi-site European research umbrella with shared training infrastructure and a similar relationship to national funding cycles.

TypeBroad incumbent
Description

US non-profit basic-research institute in molecular and cellular biology. Comparable as a non-commercial, talent-driven research organization producing foundational life-science outputs.

TypeEmerging player
Description

US non-profit research organization producing large-scale, open-access scientific data resources (e.g., brain atlases, cell atlases). Highly comparable to EMBL-EBI in mission of building reusable community data assets.

9Swiss Institute of Bioinformatics (SIB)
TypeDirect peer
Description

Swiss non-profit coordinating bioinformatics resources, databases, and computational biology research. Direct counterpart to EMBL-EBI in maintaining open data resources (e.g., UniProt, neXtProt) for the scientific community.

TypeBroad incumbent
Description

US government agency funding and conducting biomedical research at massive scale, including training programs analogous to EMBL's. Comparable as the dominant public funder of life-science research in its region, with similar training and data-sharing mandates.

Market position
Strengths4 records

Each record includes

Headline, Details, Source

Weaknesses4 records

Each record includes

Headline, Details, Source

Competitive moat6 records

Each record includes

Type, Details

Key risks6 records

Each record includes

Headline, Details, Source

Key highlights7 records

Each record includes

Headline, Details, Source

Customer concentration

Classification, Details

Segment3 records

Each record includes

Title, Type, Primary, Description, Pain point addressed, Use case, Source

Ideal customer profile3 records

Each record includes

Profile, Firmographic size, Sales motion, Sales cycle length, Buying structure, Purchase trigger, Buyer persona, Geography, Industry vertical, Primary use case, Description, Pain points, Evidence proof points, Target buyer

Technology focused
Yes
API detail
Has APIbool
Yes

Docs URL, Description

AI capability7 records

Each record includes

Type, Description, Source

AI maturity
App detail

Has app

Feature4 records

Each record includes

Title, Differentiator, Description, Source

Core technology
Revenue estimate
Valuation estimate
Number of profiles
Profiles1 record

Each record includes

Name, Designation, Designation category, Overview, Profile commentary, Source

Subsidiaries1 record

Each record includes

Name, Acquired on, Relationship type, Type, Business focus

No data
Funding overview

Funding stage, Last funding date, Total funding USD

Funding rounds

Each record includes

Round, Amount USD, Date, Pre money valuation, Total investors, Investors, News

Investors

Each record includes

Name, Type, Date of entry, Rounds participated, Website

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Each record includes

Name, Acquisition type, Announced date, Completed date, Status, Website, News

Investment

Each record includes

Name, Round, Announced date, Lead investor, Website, News

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

EMBL

Life Sciences Researchembl.org

The European Molecular Biology Laboratory is an intergovernmental life sciences research organization founded in 1974, operating across six European sites and serving academic researchers, PhD students, and industry with open-access bioinformatics data resources, advanced training, and specialized research facilities.

What EMBL does

The European Molecular Biology Laboratory (EMBL) is an intergovernmental research organization founded in 1974 and headquartered in Heidelberg, Germany, operating Europe's flagship life sciences laboratory across six sites: Heidelberg, Barcelona, Grenoble, Hamburg, Hinxton (EMBL-EBI), and Rome. EMBL performs fundamental molecular biology research spanning structural biology, computational biology, epigenetics, neurobiology, and infection biology, and delivers services through specialized facilities including synchrotron beamlines, the EMBL Imaging Centre, and the world's primary open-access bioinformatics data resources.

EMBL's core product surface consists of open-access data platforms — the Ensembl genome browser covering 5,000+ species and the AlphaFold Protein Structure Database with 1.7 million predicted protein complexes, delivered in partnership with Google DeepMind and NVIDIA — alongside scientific instrumentation including the EasyGrid cryo-EM automation system and BSxCuBE-Web BioSAXS interface. EMBL-EBI provides programmatic data access via a new GraphQL API and refget protocol. The organization also operates an international PhD programme and an EMBL Events platform hosting 50+ annual courses, conferences, and workshops covering synthetic biology, cryo-EM, bioinformatics, and proteomics.

EMBL's business model is primarily member-state government funding rather than commercial revenue, supplemented by fee-based training (500-1,100 EUR per participant for in-person events, 190-290 EUR for virtual) and industry sponsorship. The organization serves academic researchers, PhD students, and early career scientists as primary users, with industry researchers and corporate partners (Leica Microsystems, NVIDIA, DeepMind) as a secondary segment. Technology transfer is beginning via a new spin-off vehicle for EasyGrid commercialization, indicating a nascent revenue diversification beyond grant funding.

EMBL firmographics

Firmographics
Name
EMBL
Legal name
European Molecular Biology Laboratory
Website
https://embl.org
Company type
Private
Founded year
1974
Operating status
Operating
Headcount range
1,001–5,000 employees
Short description
The European Molecular Biology Laboratory is an intergovernmental life sciences research organization founded in 1974, operating across six European sites and serving academic researchers, PhD students, and industry with open-access bioinformatics data resources, advanced training, and specialized research facilities.
Ownership category
akta.pro rank

EMBL industry classification

Industry
Product category
Life Sciences Research
NAICS
Research and Development in Biotechnology (except Nanobiotechnology) (541714), Research and Development in the Physical, Engineering, and Life Sciences (54171), Colleges, Universities, and Professional Schools (611310), Professional and Management Development Training (61143)
SIC
Services-Commercial Physical & Biological Research (8731), Services-Educational Services (8200)
akta.pro primary industry
Knowledge Management & Scientific Collaboration / Literature Intelligence (HLAGAJAN)
akta.pro secondary industry
Transcriptomics & Gene Expression Profiling Services (HLAGANAE)

Keywords

  • Molecular biology research
  • Bioinformatics data resources
  • Structural biology services
  • Scientific training programs
  • Life sciences research

Where EMBL is headquartered

Location

Headquarters

HQ city
Heidelberg
HQ country
Germany
HQ region
Europe

Offices6 records

Markets served

EMBL business model

Business model
GTM type
B2B
Offering type
Services
Cost components
Personnel, Operations, Technology or R&D, Infrastructure, Marketing or Sales, Others

Pricing tiers

ModelBillingPrice
SubscriptionOne time/ perpetual licenseAcademic/Researcher registration fee
SubscriptionOne time/ perpetual licensePhD Student registration fee
SubscriptionOne time/ perpetual licenseIndustry registration fee
SubscriptionOne time/ perpetual licenseVirtual Conference Registration

Distribution channels4 records

Marketing channels4 records

EMBL product offering

Product offering

Core offering

EMBL is an intergovernmental life sciences research organization that performs fundamental molecular biology research and delivers scientific services across six European sites. It provides open-access bioinformatics data resources (Ensembl, AlphaFold Protein Structure Database), develops novel scientific instrumentation (EasyGrid cryo-EM, BSxCuBE-Web), and offers specialized training programs, courses, and conferences through its Advanced Training Centre. The organization serves academic researchers, PhD students, and industry researchers worldwide through its facilities, data resources, and educational offerings.

Product overview

EMBL (European Molecular Biology Laboratory) is Europe's life sciences laboratory operating across six sites (Barcelona, Grenoble, Hamburg, Heidelberg, Hinxton/EMBL-EBI, Rome). The organization provides a suite of research products and services including: the Ensembl genome browser offering free genome annotation for over 5000 species with new GraphQL API access; the AlphaFold Protein Structure Database (with 1.7M predicted protein complexes) in partnership with Google DeepMind and NVIDIA; the EasyGrid cryo-EM automation system; BSxCuBE-Web for automated BioSAXS experiments; and EMBL Events providing courses, conferences, and workshops. EMBL-EBI provides open data resources and computational biology research, while the EMBL Imaging Centre offers advanced microscopy services. Services are delivered through an events platform with both virtual and on-site participation options.

Differentiator

Problem solved

Functional benefit

Brands

  • EMBL-EBI: European Bioinformatics Institute - provides open data resources that enable discovery, and performs research in computational biology

Products and services

  • Ensembl Genome Browser

Quantifiable outcome

  • Sevenfold improvement in vitrification quality for cryo-EM sample preparation compared to traditional methods
  • +2 more outcomes

Companies that use EMBL

Customer profile

Segments3 records

Ideal customer profiles3 records

EMBL technology and API

Technology

Technology focussed Yes

API detail

Has API
Yes
API docs
API detail

Core technology

AI maturity

App detail

AI capability7 records

Feature4 records

EMBL partnerships and signals

Strategic signal

Partnerships

Seven partnerships are on record, tiered core and minor.

  • NVIDIAcoreStrategic or Co-development PartnerNVIDIA partnership for AI infrastructure in life sciences, including expansion of the AlphaFold Protein Structure Database with Google DeepMind and EMBL, adding 1.7 million predicted protein complexes. NVIDIA GTC 2026 featured announcements around this collaboration in healthcare, robotics, and drug discovery.
  • Leiden University Medical Center (LUMC)coreStrategic or Co-development PartnerCollaborative research partnership with EMBL Heidelberg and Mi-EOCRC consortium for microbiome study analyzing 6,799 gut microbiome profiles from 27 studies, identifying robust colorectal cancer microbiome signature.
  • ESRF (European Synchrotron Radiation Facility)coreStrategic or Co-development PartnerCollaboration with ESRF beamline BM29 for BioSAXS experiments, where EMBL Grenoble developed BSxCuBE-Web interface to automate high-throughput BioSAXS experiments.
  • EMBOcoreStrategic or Co-development PartnerJoint funding and organization of courses and conferences. EMBO and EMBL jointly fund symposia promoting scientific communication and collaboration in the European research area.
  • Leica MicrosystemscoreStrategic or Co-development PartnerCooperation for STED nanoscopy course, with Leica providing expert faculty and technology demonstrations. Course organized in cooperation with Leica Microsystems CMS GmbH.
  • Google DeepMindcoreStrategic or Co-development PartnerPartnership for AlphaFold Protein Structure Database expansion, adding 1.7 million predicted protein complexes accessible to the global scientific community.
  • EMBL Advanced Training Centre Corporate Partnership ProgrammeminorGTM or Marketing PartnerCorporate partnership program providing financial assistance for training courses in the form of travel grants, childcare grants, and registration fee waivers.

Scale indicators7 records

Recent moves7 records

Expansion highlights5 records

EMBL competitors and assessment

Company assessment

Direct peers

  • Broad Institute: US-based biomedical and genomic research institute operating at comparable scale in molecular biology, genomics, and computational biology. Most direct analogue to EMBL's pan-disciplinary research-and-data model, including flagship data resources analogous to Ensembl.
  • Wellcome Sanger Institute: UK-based genomic and bioinformatics research institute with comparable focus on large-scale molecular biology, genome annotation, and open data resources. Closely comparable to EMBL-EBI in mission and outputs.
  • Francis Crick Institute: London-based biomedical research institute with multi-disciplinary molecular biology programs and significant training activity. Comparable as a European, government-and-philanthropy funded research organization serving a similar scientific audience.
  • Swiss Institute of Bioinformatics (SIB): Swiss non-profit coordinating bioinformatics resources, databases, and computational biology research. Direct counterpart to EMBL-EBI in maintaining open data resources (e.g., UniProt, neXtProt) for the scientific community.

Broad incumbents

  • Howard Hughes Medical Institute (HHMI): Large US biomedical research organization supporting Investigator-led labs across many institutions. Comparable as a sustainable, mission-driven funder of fundamental life-science research with strong training and open-science commitments.
  • Max Planck Society: German government-funded research society operating numerous institutes in life sciences and beyond. Comparable in scale, public funding model, and training mission; complementary geographically (Germany-based, like EMBL Heidelberg).
  • CNRS (Centre national de la recherche scientifique): France's largest government-funded research organization covering life sciences and beyond. Comparable as a public, multi-site European research umbrella with shared training infrastructure and a similar relationship to national funding cycles.
  • Salk Institute for Biological Studies: US non-profit basic-research institute in molecular and cellular biology. Comparable as a non-commercial, talent-driven research organization producing foundational life-science outputs.
  • NIH (National Institutes of Health): US government agency funding and conducting biomedical research at massive scale, including training programs analogous to EMBL's. Comparable as the dominant public funder of life-science research in its region, with similar training and data-sharing mandates.

Emerging players

  • Allen Institute: US non-profit research organization producing large-scale, open-access scientific data resources (e.g., brain atlases, cell atlases). Highly comparable to EMBL-EBI in mission of building reusable community data assets.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat6 records

Key risks6 records

Key highlights7 records

Customer concentration

EMBL social profiles

Digital presence

EMBL financial estimates

Financial estimate

Revenue estimate

Valuation estimate

EMBL leadership team

Management profile

Number of profiles

Profiles1 record

EMBL subsidiaries and ownership

Company hierarchy

Subsidiaries1 record

EMBL funding detail

Funding detail

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

EMBL M&A and investment

M&A and investment

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about EMBL

What does EMBL do?

EMBL is an intergovernmental life sciences research organization that performs fundamental molecular biology research and delivers scientific services across six European sites. It provides open-access bioinformatics data resources (Ensembl, AlphaFold Protein Structure Database), develops novel scientific instrumentation (EasyGrid cryo-EM, BSxCuBE-Web), and offers specialized training programs, courses, and conferences through its Advanced Training Centre. The organization serves academic researchers, PhD students, and industry researchers worldwide through its facilities, data resources, and educational offerings.

Is EMBL a public or private company?

EMBL is a private company. It is classified as state government owned and is currently operating.

When was EMBL founded?

EMBL was founded in 1974. It employs 1,001 to 5,000 people.

Where is EMBL based?

EMBL is headquartered in Heidelberg, Germany, in the Europe region.

Who are EMBL's main competitors?

Direct peers on record are Broad Institute, Wellcome Sanger Institute, Francis Crick Institute and Swiss Institute of Bioinformatics (SIB). Broad incumbents are Howard Hughes Medical Institute (HHMI), Max Planck Society, CNRS (Centre national de la recherche scientifique), Salk Institute for Biological Studies and NIH (National Institutes of Health). Allen Institute is listed as an emerging player.

Does EMBL have an API?

Yes. Ensembl provides programmatic access via Ensembl GraphQL API and refget for sequence data retrieval. Legacy access is available via Ensembl Perl API or direct MySQL database access. FTP file transfer access is provided for bulk data downloads, with a new FTP site structure serving all species together. The AlphaFold Protein Structure Database is available through Google DeepMind infrastructure with expanded access to 1.7 million predicted protein complexes. Developer documentation is at www.ebi.ac.uk/training/events/transitioning-new-ensembl-platform-genome-data-and-annotation.

What industry is EMBL in?

EMBL's product category is Life Sciences Research. Its primary akta.pro industry code is HLAGAJAN, Knowledge Management & Scientific Collaboration / Literature Intelligence, with a secondary code of HLAGANAE, Transcriptomics & Gene Expression Profiling Services. Its NAICS code is 541714 and its SIC code is 8731.

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Live signals
FoodinstituteCultivated Meat Makes Major Step Toward Lab-Grown SteakEMBL Barcelona researchers grew self-organizing bovine muscle, nerve, and blood vessel cells from embryonic stem cells, a step toward lab-grown steak. The tissue is small and requires expensive media, so mass production remains distant.Mirage NewsViral Enzyme Disables Bacterial Defenses for PhagesResearchers at EMBL Heidelberg discovered that the T7 phage utilizes a 'loose cannon' enzyme, T7 kinase, to trigger widespread phosphorylation of bacterial DNA-binding proteins, thereby disabling host immune defenses. This mechanism allows the virus to infect bacteria with robust defense systems and provides critical insights for developing bioengineered phage therapies against antimicrobial resistance.Mirage NewsProtein Degradation Rate Explains Human-Mouse Growth GapResearchers from EMBL Barcelona, PoL-TU Dresden, and EMBL Heidelberg discovered that human cells degrade proteins more slowly than mouse cells across approximately 4,000 shared proteins. This general difference in protein turnover rates provides a molecular explanation for the slower developmental tempo observed in humans compared to mice. The study identifies cellular metabolism as a key regulator of this process, linking physiological activity to developmental timing.Mirage NewsGolgi Complex Key in DNA Repair RegulationEMBL Heidelberg researchers have discovered that the Golgi complex, an organelle outside the nucleus, stores DNA-repair proteins and dynamically dispatches them to the nucleus when DNA damage occurs, matching repair proteins to specific types of damage. The study found that RAD51C, a protein strongly associated with increased risk of breast and ovarian cancers, is held at the Golgi through interaction with Giantin protein and released to the nucleus upon DNA damage, with disruption preventing proper DNA repair. This finding reframes the Golgi as an active participant in DNA damage response rather than a bystander, revealing a previously unknown layer of regulation that could open new opportunities for targeting cancer and related diseases.Mirage NewsTropical Forest Health: Insights From Above and BelowResearchers from EMBL, NASA, the Smithsonian Tropical Research Institute, and the University of Zurich conducted a soil microbiome sampling campaign in Panama in May as part of the COMADRE project, collecting 146 topsoil and humic-layer samples from the Barro Colorado Nature Monument to link satellite observations with underground microbial data. The project aims to help satellites better understand tropical forest health and resilience by adding microbial DNA and RNA sequencing to NASA's existing AVUELO airborne campaign. The samples will be analyzed at EMBL Heidelberg, EMBL Hamburg, and NASA's Jet Propulsion Laboratory to test whether underground molecular mechanisms can explain tree canopy health observed from space, potentially improving NASA's satellite models for monitoring tropical forests that account for 40% of global CO₂ sequestration.The TribuneNew study reveals how flu virus hijacks human cells to multiplyResearchers at EMBL Hamburg and collaborators from the Leibniz Research Institute for Molecular Pharmacology and Charite - Universitatsmedizin Berlin have published a study in Nature Microbiology that maps, for the first time, how influenza A virus directly rewires infected human cells by tracking virus-host protein interactions inside intact cells. The team combined cross-linking mass spectrometry with modified AlphaFold modeling to identify how the virus hijacks cellular machinery, including revealing that influenza A causes paraspeckles in the cell nucleus to dissolve, releasing RNA-binding proteins the virus uses for replication. The researchers believe this breakthrough could support development of improved flu drugs and vaccines, and their methodology could be applied to study other viruses of pandemic relevance such as H5N1.Mirage NewsFlu Virus Rewiring of Human Cells Mapped by ScientistsResearchers at EMBL Hamburg and collaborators at the Leibniz Research Institute for Molecular Pharmacology have mapped how the influenza A virus reprograms infected human cells by using cross-linking mass spectrometry combined with AlphaFold structural modeling to observe protein-protein interactions directly inside intact cells. The study, published in Nature Microbiology, revealed two key hijacking mechanisms: how the virus controls haemagglutinin protein movement through the cell's internal transport system, and how infection causes paraspeckles in the nucleus to dissolve, releasing RNA-binding proteins the virus can use for replication. The researchers believe this mapping approach could identify novel drug targets and be applied to pandemic-relevant viruses such as H5N1.Mirage NewsNovoTags: AI Proteins Illuminate Living CellsResearchers from the University of Washington, Janelia Research Campus, and EMBL Heidelberg developed a new class of synthetic fluorescent protein tags called NovoTags, using AI-driven protein design pioneered by Nobel Laureate David Baker. The tags bind to bright fluorescent dyes developed by Luke Lavis and enable scientists to simultaneously image up to 30 different proteins inside living cells using multicolour fluorescence microscopy. Future applications include combining the technology with cryo-electron tomography to study protein structures within cells at unprecedented resolution.Mirage NewsWorking Together To Facilitate BioSAXS ExperimentsThe McCarthy team at EMBL Grenoble has developed BSxCuBE-Web, a web-based interface to automate BioSAXS (Biological small-angle X-ray scattering) experiments at the ESRF beamline BM29, making high-throughput experiments accessible to both experts and non-experts. The interface enables real-time data monitoring, automated data analysis pipelines, and control of beamline parameters and sample conditions from a single platform. ARISE fellows Anton Popov and Dihia Moussaoui contributed to the project, with Popov developing microfluidic devices for the vacuum sample environment and Moussaoui testing the interface using X-ray footprinting-mass spectrometry techniques.Mirage NewsMajor Microbiome Study Finds Strong Colorectal Cancer MarkerResearchers from EMBL Heidelberg, Leiden University Medical Center (LUMC), and the Mi-EOCRC consortium reanalysed 6,799 gut microbiome profiles from 27 studies and identified a robust colorectal cancer microbiome signature that was consistent across populations, sequencing methods, and age-of-onset groups. The study, published in Cell Host & Microbe, also found that the cancer-associated microbiome pattern was linked to lower dietary fibre intake and could potentially be reduced through fibre-focused dietary interventions. While the findings represent a significant step toward understanding the microbiome's role in colorectal cancer, researchers emphasized this is not yet a diagnostic test but could serve as a foundation for future machine-learning-based detection and prevention strategies.