S3 Connected Health

Name

S3 Connected Health

Legal name

Silicon & Software Systems Ltd.

Website

https://s3connectedhealth.com

Company type

Private

Founded year

2016

Operating status

Operating

Headcount range

101–250 employees

Ownership category

akta.pro rank

Product category

Digital Health Platform

NAICS

Health Care and Social Assistance (62), Surgical and Medical Instrument Manufacturing (339112)

SIC

Surgical & Medical Instruments & Apparatus (3841), Services-Computer Integrated Systems Design (7373)

akta.pro primary industry

Connected Medical Devices & Wearables (Sensors, Patches, Implantables) (HLACAPAB)

akta.pro secondary industries

Therapeutic Companion Apps (Drug-Device-Digital Combination) (HLACANAH), Connected Therapeutics & Smart Drug Delivery Monitoring (HLACAFAL), Remote Therapeutic Monitoring (RTM) & Digital Rehabilitation Platforms (HLALABAK)

Keywords

• Digital health solutions
• Digital therapeutics development
• Connected medical devices
• Pharma digital companions
• Medtech software platform

Headquarters

HQ city

New York

HQ country

United States

HQ region

North America

Offices3 records

Markets served

GTM type

B2B

Offering type

Software

Cost components

Personnel, Technology or R&D, Operations, Marketing or Sales, Infrastructure

Revenue model

1. Digital Health Solutions Development: Custom development of digital health solutions, digital therapeutics (DTx), and Software as a Medical Device (SaMD) for pharma and medtech clients. Revenue generated through project-based professional services and solution development engagements.
2. Platform Services and Operations: Ongoing platform hosting, operation, and maintenance services for digital health solutions. Includes regulatory compliance management, data hosting, and solution scaling across markets.
3. Digital Health Consultancy: Strategy consulting services including digital health strategy development, regulatory roadmap creation, user research, and innovation workshops. Engagements follow structured methodology from definition through to launch and operation.

Pricing tiers

Go-to-market motion2 records

Distribution channels2 records

Marketing channels8 records

Core offering

S3 Connected Health designs, develops, and operates regulated digital health solutions for pharmaceutical and medical device companies on its proprietary Affinial platform. Core offerings span digital companions that support therapy adherence, chronic disease management applications, standalone and adjunct digital therapeutics (DTx), and connected medical device solutions for hospital-at-home and disease management, complemented by digital health strategy and innovation consulting services.

Product overview

S3 Connected Health is a specialist digital health partner for life sciences companies, offering a platform-plus-services architecture centered on the Affinial platform. The core Affinial platform enables creation and operation of regulated digital health solutions, which are delivered through distinct solution types including Digital Companions (therapy management apps), Chronic Disease Management solutions, Digital Therapeutics (DTx), and Connected Medical Devices solutions for medtech. The company also provides strategic Digital Health Consultancy services and Patient Support Programs. The product portfolio spans solutions for pharma companies (digital companions, chronic disease management, digital therapeutics, PSPs) and medtech companies (connected devices, hospital-at-home, disease management), supported by end-to-end services from strategy through development to operational launch.

Differentiator

Problem solved

Functional benefit

Brands

• Affinial: Digital health platform used to create and operate regulated digital health solutions for life sciences companies, supporting digital companions, chronic disease management, and digital therapeutics.
• MyBreathPrint

Products and services

• Affinial Platform A cloud-based proprietary digital health platform used to create and operate regulated digital health solutions for life sciences companies, supporting digital companions, chronic disease management, digital therapeutics, and connected medical device solutions.
• Digital Companions Digital applications and portals designed to work alongside pharmaceutical therapies to improve patient engagement and treatment adherence throughout the patient journey, targeted at pharmaceutical companies.
• Chronic Disease Management Solutions Comprehensive digital health solutions that support patients and clinicians in managing chronic diseases through applications, clinical portals, and connected devices for holistic disease management.
• Digital Therapeutics (DTx) Standalone and adjunct software-driven therapeutic interventions for the treatment, management, or prevention of diseases or disorders, requiring clinical evidence and regulatory approval, delivered for life sciences companies.
• Connected Medical Devices Solutions End-to-end digital health solutions for medtech companies including disease management, hospital-at-home, and connectivity solutions for medical equipment, including firmware development and cybersecurity for connected devices.
• Hospital-at-Home Solutions Connected medical equipment solutions enabling healthcare delivery in home settings, supporting at-home monitoring and in-hospital equipment connectivity for distributed care.
• Disease Management Solutions Solution areas for medtech companies focused on disease management through connected devices and digital health platforms.
• Digital Health Consultancy Strategic and innovation consulting services for life sciences companies including business opportunity development, user research, solution ideation, clinical pathway design, and regulatory and reimbursement strategy.
• Patient Support Programs (PSP) Customized patient support programs designed to support patients undergoing drug treatments, including pediatric support programs for rare conditions.
• MyBreathPrint Breath Analysis Solution A handheld breath analysis device and digital solution for early disease detection through volatile organic compound (VOC) analysis in exhaled breath, developed in partnership with Vocxi Health and Forj Medical.

Quantifiable outcome

• Merck published data showing adherence rates 10% higher than market average initially, growing to 25% higher as connected health solutions were extended
• +2 more outcomes

Named customers20 records

Segments3 records

Ideal customer profiles2 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

AI capability5 records

Feature4 records

Partnerships

Five partnerships are on record, tiered supporting and core.

• Digital Medicine Society (DiMe)supportingStrategic or Co-development Partner · 16 April 2026Participant in DiMe-led initiative 'Optimizing Direct-to-Patient (DTP) Strategies for Pharma' to establish operational, regulatory, and evidence-based foundations for scaling DTP healthcare models.
• Vocxi HealthcoreStrategic or Co-development Partner · 5 March 2026Partnership to develop handheld version of MyBreathPrint device for disease detection through breath analysis. Focused on miniaturizing the device, increasing manufacturability, and readying for clinical and home use. Resulted in prototype and initial production run.
• EVERSANAcoreStrategic or Co-development Partner · 26 May 2021Strategic partnership to advance the adoption and commercialization of digital health solutions across life sciences. EVERSANA provides next generation commercial services to global life sciences industry. Partnership enables combined expertise in digital health development and commercialization.
• Forj MedicalsupportingStrategic or Co-development PartnerTechnology partner for miniaturization of MyBreathPrint device. Collaboration focused on design for manufacturing and technical development of handheld breath analysis device.
• smartQarecoreStrategic or Co-development PartnerPartnership to develop cloud-based digital health platform for viQtor wearable device. Project scope evolved from at-home elderly monitoring to include hospital use for patient deterioration detection.

Scale indicators6 records

Recent moves8 records

Expansion highlights5 records

Broad incumbents

• Medidata Solutions (Dassault Systèmes): Medidata offers decentralized clinical trial technology and patient-centric digital health solutions for biopharma — overlapping with S3 Connected Health's clinical assessment capture and SaMD evidence generation capabilities for pharma clients.
• Veeva Systems: Veeva's Vault platform and Connected Health applications serve life sciences companies with regulated cloud content, clinical, and commercial platforms, representing an adjacent incumbent that could expand deeper into S3 Connected Health's SaMD and companion app territory.
• Accenture Health: Accenture's Health practice delivers digital health strategy, connected health platforms, and SaMD development to pharma and medtech, representing a larger and broader competitor with deeper enterprise sales reach than S3 Connected Health.
• IQVIA: IQVIA offers digital health, real-world evidence, and connected health solutions to life sciences companies globally, competing with S3 Connected Health for pharma digital health and SaMD engagements while operating at vastly larger scale across clinical and commercial services.
• Cognizant Life Sciences: Cognizant provides digital engineering, SaMD development, and connected health services to pharma and medical device manufacturers, competing with S3 Connected Health on custom digital health builds and platform operations at significantly larger scale.
• Deloitte Digital (Health & Life Sciences): Deloitte's Life Sciences and Health Care practice competes with S3 Connected Health on digital health strategy, connected device programs, and platform advisory for the same pharma and medtech enterprise buyers.

Direct peers

• BrightInsight: BrightInsight provides a regulated digital health platform for biopharma and medtech to build and host digital therapeutics, SaMD, and connected device software — the closest direct competitor to S3 Connected Health's Affinial platform, targeting the same pharma and medtech buyer base with a similar platform-plus-services model.
• Welldoc: Welldoc develops digital health and digital therapeutic solutions with pharma partners (including strategic collaborations with major manufacturers), targeting chronic disease management and SaMD — overlapping with S3 Connected Health's chronic disease and DTx offerings.
• Sidekick Health: Sidekick Health develops digital therapeutics and digital care programs in partnership with pharma for chronic and complex conditions, directly competing with S3 Connected Health for pharma digital companion and chronic disease management engagements.
• Voluntis (AstraZeneca): Voluntis builds digital therapeutics and connected companion apps for pharma across therapeutic areas, originally independent and now part of AstraZeneca — a direct competitor and adjacent model that illustrates both the opportunity and the consolidation risk in S3 Connected Health's space.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat6 records

Key risks5 records

Key highlights7 records

Customer concentration

• LinkedInlinkedin.com/company/s3-connected-health
• Xx.com/S3ConnectedH

Compliance2 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles9 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about S3 Connected Health