BioPlus Specialty Pharmacy

What BioPlus Specialty Pharmacy does

BioPlus Specialty Pharmacy (formerly Kroger Specialty Pharmacy) is a U.S. specialty pharmacy headquartered in Altamonte Springs, Florida, operating as a subsidiary of Carelon, the healthcare services arm of Elevance Health. Founded in 1990, the company dispenses high-cost specialty medications for chronic and complex conditions including cancer, multiple sclerosis, autoimmune diseases, hepatitis C, HIV, rheumatology, gastroenterology, and transplant, with five licensed pharmacies in California, Florida, Louisiana, and North Carolina plus a national mail-order fulfillment operation delivering next-day to patients and providers.

The company's technology layer centers on a specialty pharmacy management platform that integrates prescription processing, prior authorization workflows, clinical care coordination, and a mobile refill application. Its branded service promises — the 2 Hour Patient Acceptance Guarantee, Ready 2 Ship 2-day fulfillment, 2 Click Prescription Refills, and Tailored 2 You care management — are operational SLAs wrapped around proprietary workflow tools rather than AI-driven automation. The platform supports therapy-specific referral forms, EHR-integrated provider referrals, payer data analytics, pharma hub collaboration, and 340B program workflows.

BioPlus operates a B2B2C commercial model with six revenue streams: specialty drug dispensing reimbursements from insurers and PBMs, payer services through the BioPlus Shift program, pharmaceutical manufacturer services including hub program collaboration and limited-distribution drug network management, employer specialty benefit management, 340B program solutions for health systems, and infusion services through a Paragon Healthcare partnership. Customer acquisition flows through healthcare provider referrals, payer/insurer network inclusion, employer benefit carve-outs, and pharmaceutical co-marketing programs. The company is URAC, ACHC, and NABP accredited and employs 251-500 staff.

Name

BioPlus Specialty Pharmacy

Legal name

BioPlus Specialty Pharmacy Services, LLC

Website

https://bioplusrx.com

Company type

Private

Founded year

1990

Operating status

Operating

Headcount range

251–500 employees

Short description

BioPlus Specialty Pharmacy is a U.S. specialty pharmacy (Carelon/Elevance Health subsidiary) that dispenses high-cost specialty medications for chronic conditions including cancer, MS, autoimmune, HIV, and HCV, serving patients, providers, payers, pharma, employers, and 340B-covered entities through mail-order and five state-licensed pharmacy locations.

Ownership category

akta.pro rank

Product category

Specialty Pharmacy Services

NAICS

Pharmacies and Drug Retailers (456110)

SIC

Retail-Drug Stores And Proprietary Stores (5912), Wholesale-Drugs, Proprietaries & Druggists' Sundries (5122)

akta.pro primary industry

Specialty Pharmacies (Complex/High-Cost Therapies) (HLAFALAC)

akta.pro secondary industries

Specialty Pharmacy & Complex Therapy Management Platforms (HLACAKAG), Specialty Pharmacy & Biologics Distribution (CRAOAHAD), Biologics & Biosimilars Distributors (HLAIAJAH)

Keywords

• Specialty pharmacy services
• Medication therapy management
• Chronic disease pharmacy
• Patient care coordination
• Specialty drug distribution

Headquarters

HQ city

Altamonte Springs

HQ country

United States

HQ region

North America

Offices5 records

Markets served

GTM type

B2B and B2C

Offering type

Services

Cost components

Personnel, Operations, Supply Chain, Marketing or Sales, Technology or R&D, Infrastructure

Revenue model

1. Specialty Pharmacy Dispensing: BioPlus generates revenue primarily through dispensing specialty medications to patients with chronic conditions. Revenue is derived from insurance reimbursements, pharmacy benefit manager (PBM) contracts, and direct payer relationships. The pharmacy handles high-cost specialty drugs for conditions including cancer, multiple sclerosis, autoimmune diseases, and other complex therapeutic areas.
2. Payer Services: Provides specialty pharmacy benefit management services to payers including formulary management, utilization optimization, and custom data reporting through the BioPlus Shift Program for cost savings on specialty therapies.
3. Pharma Partner Services: Offers pharmaceutical manufacturers services including patient onboarding and retention, copay program maximization, field sales support, limited distribution drug network management, and hub program collaboration.
4. Employer Specialty Benefit Management: Helps employers manage specialty pharmacy benefits and achieve savings through the BioPlus Shift program, working with PBMs to create specialty pharmacy carve-out programs.
5. 340B Program Services: Provides 340B program solutions for health systems including expanded in-network infusion access, coordinated specialty and infusion workflows, and program visibility and revenue retention.

Go-to-market motion2 records

Distribution channels4 records

Marketing channels7 records

Core offering

BioPlus Specialty Pharmacy is a mail-order and multi-location specialty pharmacy that dispenses high-cost specialty medications and provides clinical care coordination for patients with chronic, complex conditions such as cancer, multiple sclerosis, autoimmune diseases, hepatitis C, HIV, rheumatology, and transplant. Core operations are wrapped in the proprietary "Power of 2" service promise: a 2-Hour Patient Acceptance Guarantee, 2-Day Ready-to-Ship fulfillment, and 2-Click mobile prescription refills, supported by prior authorization assistance, 24/7 pharmacist access, and financial assistance programs.

Product overview

BioPlus Specialty Pharmacy (formerly Kroger Specialty Pharmacy) is a specialty pharmacy that provides comprehensive medication management services for patients with chronic and complex conditions including cancer, multiple sclerosis, autoimmune diseases, hepatitis C, HIV, rheumatology, gastroenterology, and transplant. The company operates a core specialty pharmacy service platform with integrated modules including the 2 Hour Patient Acceptance Guarantee, Ready 2 Ship 2-day fulfillment, and 2 Click mobile refill capabilities. Additional offerings include the BioPlus Shift payer program, Pharma partner services with hub program collaboration, 340B solutions for health systems, Oncology Center of Excellence, payer analytics reporting, and infusion services. The company is part of the Carelon family (an Elevance Health company) and holds URAC and ACHC accreditations.

Differentiator

Problem solved

Functional benefit

Brands

• 2 Hour Patient Acceptance Guarantee: Service guarantee providing notification to physician offices within 2 hours on patient acceptance.
• Ready 2 Ship
• 2 Click Prescription Refills
• Tailored 2 You
• BioPlus Shift
• BioPlus 340B Solutions

Products and services

• Specialty Pharmacy Dispensing and Medication Management Comprehensive specialty pharmacy services for patients with chronic, complex conditions including cancer, multiple sclerosis, autoimmune diseases, HIV, hepatitis C, rheumatology, gastroenterology, dermatology, neurology, osteoporosis, and transplant. Includes prior authorization assistance, 24/7 pharmacist access, financial assistance, and adherence support.
• 2 Hour Patient Acceptance Guarantee Guarantee to contact a referred patient's insurance company about pharmacy benefits and notify the prescribing physician office within 2 hours regarding whether the patient is accepted for specialty therapy treatment.
• Ready 2 Ship 2-Day Fulfillment Covered, qualifying specialty prescriptions are packed and ready to ship within 2 days of approval, with next-day delivery to the patient's door or doctor's office.
• 2 Click Prescription Refills Mobile App Mobile application that allows patients to refill qualifying medications with 2 clicks and receive text/email refill reminders approximately 10 days before refill due date.
• Tailored 2 You Personalized Patient Care Management Clinical teams provide personalized high-touch or high-tech support across the treatment journey, navigating therapy guidelines, access hurdles, adherence, and provider communication.
• BioPlus Shift Specialty Pharmacy Benefit Management Program Specialty carve-out program that delivers optimized formulary management, appropriate utilization, custom data analytics and reporting, and cost savings of 10-20% on specialty therapies for payers and employers.
• Pharma Partner Services and Hub Programs Comprehensive support for biopharmaceutical manufacturers including program design and implementation, pull-through, customized data solutions, copay program maximization, field sales support, limited distribution drug network management, and hub program collaboration.
• BioPlus 340B Program Solutions for Health Systems Specialty and infusion pharmacy program for 340B covered entities (FQHCs, rural hospitals, safety-net providers), offering expanded in-network infusion access, coordinated specialty and infusion workflows, and 340B program visibility and revenue retention.
• Oncology Center of Excellence Specialized oncology care coordination and clinical support offering for cancer patients on specialty therapies, including dedicated clinical training and patient-centered resources.
• Payer Data Analytics and Reporting Custom data collection and reporting for payers covering diagnoses analysis, patient utilization tracking, transactional analysis, provider profiling, adherence and compliance analysis, and performance assessment.
• Therapy-Specific Referral Forms and Drug List Specialized referral forms and drug formularies organized by therapeutic category, including Alpha 1 Antitrypsin, Blood Modifying Agents, Clotting Factor, Dermatology, Gastroenterology, HCV, HIV, Immunology, Neurology (MS), Oncology, Osteoporosis, Rheumatology, and Transplant.
• Infusion Services Medical infusion therapy services with national nursing coverage for patients requiring intravenous specialty medications across multiple disease states.

Quantifiable outcome

• 97% patient survey satisfaction rate in 2025
• +5 more outcomes

Named customers6 records

Segments6 records

Ideal customer profiles6 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature4 records

Partnerships

Four partnerships are on record, tiered minor and core.

• Pinksocks LifeminorStrategic or Co-development Partner · 1 January 2020BioPlus collaborates with Pinksocks Life, a nonprofit focused on human connection in healthcare. Through this collaboration, nearly 50,000 pairs of pinksocks have been distributed to oncology patients and healthcare workers since 2020. Dr. Nick Maroulis of BioPlus authored an article in Pharmacy Times highlighting this initiative to inspire compassion and connection in cancer care.
• CareloncoreOthersBioPlus is a Carelon Company. Carelon provides healthcare services that touch the lives of 1 in every 3 Americans. Together with BioPlus, Carelon supports consumers, families, and communities across the entire care journey - connecting them to the care, support, and resources they need to lead healthier lives. This parent-subsidiary relationship provides BioPlus with significant backing and integration into a major healthcare enterprise.
• Paragon HealthcarecoreStrategic or Co-development PartnerBioPlus + Paragon Healthcare partnership provides infusion services through a Better with a Partner Network. This collaboration expands in-network infusion access for health system partners and 340B programs, helping protect 340B program value by keeping high-cost infusion therapies inside health systems. The partnership addresses fragmented infusion networks that push care outside health systems.
• ExactCare PharmacyminorStrategic or Co-development PartnerBioPlus partners with ExactCare Pharmacy to support patients with polypharmacy needs. ExactCare makes it easier for patients to manage multiple medications while enabling healthcare organizations to achieve better outcomes. This partnership supports the management of patients taking 8+ medications who benefit from a 'quarterback' overseeing potential medication interactions.

Scale indicators4 records

Recent moves7 records

Expansion highlights6 records

Direct peers

• Accredo (Express Scripts): Accredo is one of the largest specialty pharmacies in the US, owned by Express Scripts (Cigna). It directly competes with BioPlus in dispensing high-cost specialty medications for chronic conditions, with overlapping therapy categories and payer relationships.
• CVS Specialty (Caremark): CVS Specialty is the specialty pharmacy arm of CVS Health, integrated with the Caremark PBM. It competes with BioPlus across dispensing, prior authorization workflows, and limited distribution drug networks for the same chronic therapy patient populations.
• Optum Specialty Pharmacy: Optum Specialty Pharmacy (UnitedHealth Group) is a vertically integrated specialty pharmacy serving chronic disease patients. It is a direct competitor with BioPlus in dispensing, payer services, and pharma manufacturer partnerships.
• Walgreens Specialty Pharmacy: Walgreens Specialty Pharmacy dispenses specialty medications through its national retail footprint and mail-order platform. It serves the same chronic condition patient segments as BioPlus (oncology, MS, autoimmune) with comparable therapy management services.
• Humana Specialty Pharmacy: Humana Specialty Pharmacy, part of Humana Inc.'s CenterWell division, dispenses specialty medications primarily to Humana plan members. It directly competes with BioPlus in payer-aligned specialty pharmacy dispensing for chronic conditions.
• Orsini Specialty Pharmacy: Orsini is a specialty pharmacy focused on rare diseases, oncology, and complex specialty therapies. It competes with BioPlus's specialty dispensing capabilities, particularly for limited distribution drugs and high-touch chronic therapy management.
• PantherRx Rare: PantherRx Rare is a specialty pharmacy focused on rare and orphan disease therapies. It overlaps with BioPlus in chronic, high-cost specialty dispensing and competes for limited distribution drug network partnerships with manufacturers.
• Biologics by McKesson: Biologics by McKesson is an oncology-focused specialty pharmacy with national reach. It is a direct competitor with BioPlus in oncology dispensing and broader specialty therapy management for complex chronic conditions.
• Avella Specialty Pharmacy: Avella is a national specialty pharmacy providing dispensing and clinical management for complex conditions including oncology, fertility, and hepatitis C. It competes with BioPlus in payer contracting, pharma hub services, and limited distribution drug handling.

Broad incumbents

• Kroger Health: Kroger Health is the retail and pharmacy arm of Kroger Co. Although BioPlus was formerly Kroger Specialty Pharmacy and was divested/rebranded to Carelon, Kroger Health remains a broad incumbent with pharmacy and health services overlapping BioPlus's chronic care patient base.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• Facebookfacebook.com/bioplusspecialtypharmacy
• LinkedInlinkedin.com/company/137575
• Xx.com/biopluspharmacy

Compliance3 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles4 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about BioPlus Specialty Pharmacy