ZymeFlow
ZymeFlow is a privately held Houston-based chemical decontamination specialist serving refineries, petrochemical plants, and LNG facilities in 55+ countries with proprietary chemistries and the patented Vapour-Phase process, claiming 75% of the world's largest refineries as customers.
- Company typePrivate
- Founded1989
- HeadquartersHouston, United States
- Headcount251–500
- GTM typeB2B
- OfferingServices
What ZymeFlow does
ZymeFlow is a privately held chemical decontamination specialist founded in 1989 and headquartered in Houston, Texas. The company develops and applies proprietary water-based and solvent-based chemistries to remove hazardous contaminants—including hydrocarbons, pyrophoric iron sulfide, H2S, benzene, and VOCs—from refining, petrochemical, and LNG process equipment during turnarounds, maintenance, online operations, and pre-commissioning. Its product portfolio spans branded families such as ZymeFlow UN657 (water-based, VOC-compliant, biodegradable), Rezyd-X and Rezyd-HP (solvent-based heavy-oil dissolvers), CatZyme RT/LT/LTC (reactor decontamination chemistries for catalyst offloading), UltraZyme BT/FP (ultrasonic cleaning), the TankZyme family (3PS, H2S, SC, HP for tank cleaning), and the BAN Clean (Base/Acid/Neutralization) reactive chemistry approach launched in March 2025. These chemistries are deployed through the patented Vapour-Phase process, which delivers chemistry as hot vapor to reach areas that traditional liquid washes cannot.
Revenue is generated primarily through project-based decontamination service contracts at customer facilities, with proprietary chemistry sales accompanying engagements under non-public, quote-based pricing. ZymeFlow operates a global direct enterprise sales model with regional Directors of Business Development covering the US, Canada, APAC/India, Japan, Northern Europe, and Southern Europe, supported by a VP of Corporate Accounts & Sales and a channel partnership with Contract Resources for Australia, New Zealand, and Papua New Guinea. The company claims 75% of the world's 20 largest refineries as customers and executes over 200 turnaround projects annually across 55+ countries. Since December 2023 it has operated as a sister company to CR3 (an energy engineering solutions provider with 6,000+ staff) under common ownership, enabling a combined chemistry-plus-services platform spanning catalyst handling, industrial cleaning, mechanical maintenance, and shutdown/turnaround execution.
Certifications include ISO 45001 (occupational health and safety), REACH, and CEFAS; the company reports zero recordable incidents in its history. It recently opened a Canadian office in Edmonton (May 2025), launched Reactive Chemistry Solutions including HF and sulfuric alkylation capability (March 2025), and relocated its headquarters to a larger Houston facility with expanded labs (March 2026).
ZymeFlow firmographics
Firmographics- Name
- ZymeFlow
- Legal name
- ZymeFlow
- Website
- https://zymeflow.com
- Company type
- Private
- Founded year
- 1989
- Operating status
- Operating
- Headcount range
- 251–500 employees
- Short description
- ZymeFlow is a privately held Houston-based chemical decontamination specialist serving refineries, petrochemical plants, and LNG facilities in 55+ countries with proprietary chemistries and the patented Vapour-Phase process, claiming 75% of the world's largest refineries as customers.
- Ownership category
- akta.pro rank
ZymeFlow industry classification
Industry- Product category
- Industrial Decontamination Services
- NAICS
- Chemical Manufacturing (325), Hazardous Waste Treatment and Disposal (562211)
- SIC
- Chemicals & Allied Products (2800), Specialty Cleaning, Polishing And Sanitation Preparations (2842)
- akta.pro primary industry
- Chemical Tank Cleaning, Decontamination & Turnaround Waste Services (BPALAHAH)
- akta.pro secondary industries
- Industrial Wastewater Treatment Chemicals (IMAEAJAC), Gas Processing & NGL Recovery (Dehydration, Sweetening, Cryogenic Recovery) (EUALAGAG)
Keywords
Where ZymeFlow is headquartered
LocationHeadquarters
- HQ city
- Houston
- HQ country
- United States
- HQ region
- North America
Offices3 records
Markets served
ZymeFlow business model
Business model- GTM type
- B2B
- Offering type
- Services
- Cost components
- Personnel, Operations, Technology or R&D, Supply Chain, Marketing or Sales, Infrastructure
Revenue model
- Chemical Decontamination Services: Project-based decontamination services for refineries, petrochemical facilities, and LNG plants. Services include chemical decontamination, reactor cleaning, online/offline cleaning, tank cleaning, and pre-commissioning. Revenue generated through direct service contracts for turnaround projects.
- Proprietary Chemistry Products: Sale of proprietary chemical formulations including water-based and solvent-based chemistries. Products include ZymeFlow UN657, Rezyd-X, Rezyd-HP, CatZyme chemistries, UltraZyme products, and TankZyme product family. Chemistry sales accompany service engagements.
Go-to-market motion3 records
Distribution channels2 records
Marketing channels5 records
ZymeFlow product offering
Product offeringCore offering
ZymeFlow delivers chemical decontamination services for hydrocarbon process equipment at refineries, petrochemical plants, and LNG facilities, using proprietary water-based and solvent-based chemistries (UN657, Rezyd-X, Rezyd-HP, CatZyme, UltraZyme, TankZyme, BAN Clean) applied via the patented Vapour-Phase process. Core services include reactor cleaning, online and offline cleaning, tank cleaning, pre-commissioning and passivation, and effluent management, executed by field teams during plant turnarounds.
Product overview
ZymeFlow is a chemical decontamination company offering a unified portfolio of proprietary chemistries and application services for the refining and petrochemical industries. The core product line includes water-based and solvent-based chemistries (UN657, Rezyd-X, Rezyd-HP, CatZyme series, UltraZyme series, TankZyme series, BAN Clean) delivered through proprietary methods like the Vapour-Phase process. These chemistries are complemented by service offerings including Chemical Decontamination, Reactor Cleaning, Online/Offline Cleaning, Effluent Management, and Pre-commissioning. The entire family of ZymeFlow chemistries are complementary and can be used together safely and effectively. The company also owns CR3, an energy engineering solutions company providing catalyst handling, industrial cleaning, mechanical maintenance, and shutdown/turnaround services.
Differentiator
Problem solved
Functional benefit
Brands
- UltraZyme: Ultrasonic cleaning chemistries for exchangers, hoses, and components
- TankZyme
- CatZyme
- ZymeFlow UN657
- Rezyd-X
- Rezyd-HP
- BAN Clean
- Vapour-Phase
Products and services
- Chemical Decontamination
- Vapour-Phase Process
- ZymeFlow UN657
- Rezyd-X Solvent-based chemistry for dissolving heavy hydrocarbon sludge; can be reprocessed in-plant to reduce disposal needs and is safe and flexible for internal circulation or online treatments.
- Rezyd-HP High-potency chemistry with the highest solvency index on the market, formulated to rapidly break down heavy oils, tar, and asphalt deposits while enhancing cutter stock circulation and reducing the need for mechanical cleaning.
- CatZyme RT Original reactor decontamination chemistry with broad operating window (220-340 degrees C / 425-650 degrees F). Injected into hot hydrogen stream to rapidly strip residual gases, collapse LELs, and free compacted fines; REACH-certified.
- CatZyme LT Lower-temperature reactor decontamination chemistry engineered for sensitive precious-metal catalysts, delivering fast LEL reduction at temperatures as low as 400 degrees F with added margin against exotherms.
- UltraZyme BT Concentrated solvent-surfactant blend engineered for ultrasonic and circulation baths that attacks residual oils, greases, and asphaltenes with high solvency and customizable strength. Low-foaming, non-exothermic, and filter-safe.
- UltraZyme FP Biodegradable surface cleaner for pre-treatment or post-treatment around ultrasonic operations that pairs surfactant power with water-soluble solvent to instantly remove heavy hydrocarbons, oils, and H2S residues. EPD-certified components.
- TankZyme 3PS Non-entry three-phase separation chemistry for paraffinic and heavy-crude tanks that circulates to split hydrocarbons, water, and inorganics into three distinct layers; recovered oil meets BS&W specs.
- TankZyme H2S One-step sour-water eliminator for H2S and pyrophorics in sour-water tanks using a mild oxidizer injected directly into the vessel, permanently eliminating H2S with no exotherms; non-toxic and 100% biodegradable.
- TankZyme SC One-step oxidation and de-oiling chemistry for storage and product tanks that oxidizes sulfides/pyrophorics, de-oils solids, and promotes rapid VOC liberation via steam or water injection.
- TankZyme HP High-potency solvent additive dosed at 1-3% into LCO, diesel, naphtha, kerosene, light sweet crude, or HVGO to dissolve asphaltics and polymeric deposits; tolerates temperatures up to approximately 400 degrees F.
- BAN Clean Base, Acid, Neutralization reactive cleaning approach using stepwise application of engineered chemistries to dissolve organic sludge and heavy hydrocarbons, dissolve inorganic scales, and balance chemistry for safe handling and waste disposal.
- Reactive Chemistry Solutions Service line using advanced chemical reactions to safely neutralize hazardous contaminants, restore equipment performance, and reduce operational risks, including specialized decontamination for hydrofluoric (HF) and sulfuric acid alkylation units through innovative chemical neutralization.
- Reactor Cleaning Specialized cleaning service for fixed-bed reactors using CatZyme chemistries to reduce LELs and personnel risks during catalyst offloading and reactor preparation for inspection.
- Online and Offline Cleaning Chemical cleaning services delivered either while equipment remains in service (online) or during shutdown (offline), using solvent-based chemistries to maintain heat exchanger efficiency without disrupting operations.
- Pre-commissioning and Passivation Service for preparing new or modified systems for startup, ensuring equipment is clean and properly conditioned prior to commissioning.
- Effluent Management Management of waste streams generated during decontamination with chemistries designed to be wastewater-friendly and minimize impact on treatment facilities.
- Project Management and Engineering Engineered planning services providing custom solutions with detailed planning for decontamination projects, executed alongside chemical decontamination engagements.
- Chemical Cleaning Chemical cleaning service offering for industrial process equipment, listed as a distinct service line on the ZymeFlow website alongside chemical decontamination.
Quantifiable outcome
- Complete decontamination in 8-12 hours vs. 7-14 days for manual cleaning
- +4 more outcomes
Companies that use ZymeFlow
Customer profileNamed customers10 records
Segments3 records
Ideal customer profiles3 records
ZymeFlow technology and API
TechnologyTechnology focussed No
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Feature11 records
ZymeFlow partnerships and signals
Strategic signalPartnerships
Three partnerships are on record, tiered core, flagship and minor.
- Contract ResourcescorePartnership brings ZymeFlow's chemical solutions along with Contract Resources' service and execution capabilities to mutual clients in Australia, New Zealand, and Papua New Guinea. Contract Resources serves as the local delivery partner while ZymeFlow provides proprietary chemistries and technical expertise. Both companies share commitment to best-in-class industry solutions and continuous improvement.
- CR3flagshipZymeFlow and CR3 are under common ownership, combining ZymeFlow's chemical decontamination expertise with CR3's energy engineering solutions. CR3 provides industrial cleaning, catalyst handling, mechanical maintenance, pipeline services, and shutdown/turnaround services through facilities in Thailand, Singapore, Malaysia, Middle East, and India. CR3 employs over 6,000 staff. This collaboration enables both companies to provide broader services, innovative products, and seamless customer experience.
- Liberty Energy SolutionsminorLiberty Energy Solutions supported ZymeFlow's relocation to new headquarters location at 12055 Kurland Drive in Houston, TX in 2026.
Scale indicators6 records
Recent moves8 records
Expansion highlights7 records
ZymeFlow competitors and assessment
Company assessmentEmerging players
- Aquatech International: Aquatech provides industrial water and process treatment solutions to refineries and petrochemical operators, with overlapping chemistry and effluent management capabilities relative to ZymeFlow's chemistry portfolio.
Broad incumbents
- Petrofac: Petrofac provides operations, maintenance, and turnaround services to refineries and petrochemical operators, overlapping with ZymeFlow in providing industrial services to energy industry customers.
- Clean Harbors: Clean Harbors is a large environmental and industrial services company offering refinery turnaround cleaning, hazardous waste management, and industrial decontamination as part of a broad service portfolio overlapping with ZymeFlow's offering.
- Worley: Worley is a global energy and resources engineering services firm offering turnaround, maintenance, and industrial cleaning services to refiners and petrochemical operators, comparable in customer profile though broader in scope.
- Bilfinger: Bilfinger provides industrial services to the process industries including refinery maintenance, turnaround support, and cleaning services in Europe and globally, comparable to ZymeFlow's customer base.
- Veolia Environmental Services: Veolia operates industrial cleaning, hazardous waste handling, and refinery services globally through its environmental services segment, overlapping with ZymeFlow in industrial decontamination and effluent management.
Direct peers
- HydroChemPSC: HydroChemPSC is one of the largest industrial cleaning and chemical decontamination companies in North America, directly competing with ZymeFlow in refinery and petrochemical turnaround cleaning using chemical circulation and specialty chemistries.
- BrandSafway (formerly Furmanite): BrandSafway's Furmanite legacy business provides specialty industrial services including on-site machining, bolting, and chemical cleaning for refineries and petrochemical plants, directly competing with ZymeFlow in turnaround services.
- CR3 (Affiliated): CR3 is ZymeFlow's sister company under common ownership, providing energy engineering, industrial cleaning, catalyst handling, and turnaround services in APAC and the Middle East; a direct operational peer in adjacent geographies and services.
Regional players
- MUE Industries: MUE Industries is an industrial services firm focused on refinery and petrochemical turnaround and maintenance in North America, providing competing specialty cleaning and mechanical services to similar downstream customers.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat6 records
Key risks5 records
Key highlights7 records
Customer concentration
ZymeFlow social profiles
Digital presenceZymeFlow compliance and trust
Trust signalCompliance3 records
ZymeFlow financial estimates
Financial estimateRevenue estimate
Valuation estimate
ZymeFlow leadership team
Management profileNumber of profiles
Profiles8 records
ZymeFlow subsidiaries and ownership
Company hierarchySubsidiaries1 record
ZymeFlow funding detail
Funding detailFunding overview
Funding rounds
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
ZymeFlow M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about ZymeFlow
What does ZymeFlow do?
ZymeFlow delivers chemical decontamination services for hydrocarbon process equipment at refineries, petrochemical plants, and LNG facilities, using proprietary water-based and solvent-based chemistries (UN657, Rezyd-X, Rezyd-HP, CatZyme, UltraZyme, TankZyme, BAN Clean) applied via the patented Vapour-Phase process. Core services include reactor cleaning, online and offline cleaning, tank cleaning, pre-commissioning and passivation, and effluent management, executed by field teams during plant turnarounds.
Is ZymeFlow a public or private company?
ZymeFlow is a private company. It is classified as unknown and is currently operating.
When was ZymeFlow founded?
ZymeFlow was founded in 1989. It employs 251 to 500 people.
Where is ZymeFlow based?
ZymeFlow is headquartered in Houston, United States, in the North America region.
How does ZymeFlow make money?
Two revenue lines are on record. Chemical Decontamination Services are the primary driver. The others are proprietary Chemistry Products.
Who are ZymeFlow's main competitors?
Aquatech International is listed as an emerging player. Broad incumbents are Petrofac, Clean Harbors, Worley, Bilfinger and Veolia Environmental Services. Direct peers are HydroChemPSC, BrandSafway (formerly Furmanite) and CR3 (Affiliated). MUE Industries is listed as a regional player.
Does ZymeFlow have an API?
No public API is recorded for ZymeFlow.
What industry is ZymeFlow in?
ZymeFlow's product category is Industrial Decontamination Services. Its primary akta.pro industry code is BPALAHAH, Chemical Tank Cleaning, Decontamination & Turnaround Waste Services, with a secondary code of IMAEAJAC, Industrial Wastewater Treatment Chemicals. Its NAICS code is 325 and its SIC code is 2800.