What Scisco Genetics does

Scisco Genetics is a privately held specialty genomics company headquartered in Seattle, Washington, that provides high-resolution genotyping solutions and services for complex immune gene systems, including HLA, KIR, MICA/B, Fc Receptor, and IGHG loci. Founded in 2012 by Daniel Geraghty, the company operates as an ASHI-accredited and CLIA-certified clinical laboratory serving clinical and research customers globally. Its core technology is a Next Generation Sequencing workflow on the Illumina MiSeq platform, coupled with proprietary ScisGo assay kits (HLA-v6, KIR-v3, MICAB-v3, FcR/IGHG-v2, Chimerism MD) and the ScisCloud/GeMS analysis software for cloud-based typing and data management. The technology uses phased, in-phase sequencing combined with an enhanced proprietary database integrating IMGT, NCBI GenBank, and 1000 Genomes Project data across 25 populations to resolve allele ambiguities and detect null alleles that traditional and lower-resolution methods miss.

The company operates a dual revenue model: (1) fee-for-service laboratory testing where customers submit DNA samples and receive detailed genotyping reports, with quoted turnaround times such as 30 hours for HLA typing and 12 hours for chimerism, and (2) direct sales of proprietary ScisGo reagent kits (HLA v6 kits, Chimerism kits, Fc-FcR kits) that allow external laboratories to perform NGS-based genotyping on their own MiSeq instruments. Pricing is quote-based and not publicly disclosed, with order processes mediated through manifest submission, email, and phone channels. The go-to-market is B2B sales-led, targeting transplant centers and hospitals (donor-recipient matching), pharmaceutical and biotechnology firms (Fc receptor genotyping for therapeutic antibody development and ADCC optimization), and academic research institutions (immunogenetics and population genetics studies). Marketing relies on the company website with a peer-reviewed publication library, scientific society references, and direct sales outreach, with distribution positioned as global for both service and kit channels.

Scisco Genetics is a lean operation of 11-50 employees with no disclosed external funding, parent company, or M&A activity, and no named enterprise customers or revenue figures in the public record. Its competitive positioning rests on regulatory credentials (ASHI and CLIA), a vertically integrated assay-software-database stack, and validated performance metrics including greater than 99% accuracy for DRB1 and DQB1 genotyping, detection of all known null alleles, and chimerism sensitivity down to 0.1%. The business model is that of a niche specialty clinical laboratory and reagent supplier rather than a high-venture-backed scaling platform.

Name

Scisco Genetics

Legal name

Scisco Genetics Inc.

Website

https://sciscogenetics.com

Company type

Private

Founded year

2012

Operating status

Operating

Headcount range

11–50 employees

Short description

Scisco Genetics is a Seattle-based ASHI/CLIA-certified clinical laboratory that provides NGS-based high-resolution genotyping services and reagent kits for HLA, KIR, MICA/B, Fc Receptor, and IGHG immune gene systems, serving transplant centers, pharmaceutical developers, and academic research institutions globally.

Ownership category

akta.pro rank

Product category

Immunogenetics and HLA Genotyping Services

NAICS

Medical Laboratories (621511)

SIC

Services-Medical Laboratories (8071)

akta.pro primary industry

Molecular Diagnostics & Genomics Laboratories (HLAFAMAE)

akta.pro secondary industries

Molecular & Genetic Testing (PCR/NGS/qPCR) (HLAGADAF), Genetic, Cytogenetic & Prenatal Screening IVD (HLAHAAAI), Genomic Profiling & Sequencing-Based Precision Medicine (HLAAANAA)

Keywords

• HLA genotyping services
• NGS immunogenetics testing
• Transplant matching assays
• KIR haplotype typing
• Chimerism monitoring kits

Headquarters

HQ city

Seattle

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Technology or R&D, Supply Chain, Operations, Marketing or Sales, Infrastructure

Revenue model

1. Laboratory Testing Services: Provides comprehensive genotyping services for clinical and research laboratories including HLA typing, KIR typing, MICAB typing, FcR/IGHG typing, and chimerism testing. Services include ScisGo-HLA, ScisGo-KIR, ScisGo-MICAB, ScisGo-FcR/IGHG, and ScisGo Chimerism. Customers send DNA samples for analysis and receive detailed genotyping reports.
2. Kit Sales: Sale of proprietary ScisGo genotyping kit products including HLA v6 Kits (Cat. No. HLA-24S-v6), Chimerism Kits (Cat. No. CHIM-24S-v5), and Fc-FcR Kits (Cat. No. FcFcR-96S-v2). Kits enable customers to perform their own NGS-based genotyping using the company's technology platform.

Go-to-market motion1 record

Distribution channels2 records

Marketing channels3 records

Core offering

Scisco Genetics provides high-resolution NGS-based genotyping laboratory services and reagent kits for complex immune gene systems including HLA, KIR, MICA/B, Fc Receptor, and IGHG, supported by proprietary ScisGo assays and ScisCloud/GeMS analysis software. Customers either submit DNA samples for testing or purchase kits to perform genotyping in-house for transplant matching, chimerism monitoring, disease association studies, and therapeutic antibody development.

Product overview

Scisco Genetics offers a comprehensive portfolio of NGS-based genotyping solutions for complex immune gene systems, consisting of two main product lines: laboratory testing services (ScisGo-HLA, ScisGo-KIR, ScisGo-MICAB, ScisGo-FcR/IGHG, ScisGo Chimerism MD, and Targeted Variation Detection) and research-use kit products (ScisGo™ HLA v6 Kits, ScisGo™ Chimerism Kits, ScisGo™ Fc-FcR Kits). The company also provides ScisCloud Software including GeMS (Genetics Management System) for cloud-based data storage, analysis, and visualization. All products leverage Illumina Miseq sequencing technology and share a standardized 4-reaction PCR workflow for sample preparation.

Differentiator

Problem solved

Functional benefit

Products and services

• ScisGo-HLA Genotyping Service NGS-based high-resolution genotyping service for all eleven HLA class I and class II loci, providing phased 3-field typing with detection of null alleles; intended for clinical and research laboratories, including transplant centers.
• ScisGo-KIR Genotyping Service KIR haplotype and allele typing service that determines gene copy number, haplotype structure, and targeted KIR gene allele determination; for clinical and research customers in immunogenetics and transplantation.
• ScisGo-MICAB Genotyping Service High-resolution NGS-based genotyping service for MICA and MICB genes, providing 2-field typing including detection of null alleles; for clinical and research customers studying immune gene variation.
• ScisGo-FcR/IGHG Genotyping Service High-resolution genotyping service for Fc Receptor genes and IgG constant region domains, using a proprietary database for variant phasing; intended for pharmaceutical, biotechnology, and research customers developing therapeutic antibodies.
• ScisGo Chimerism MD Service High-sensitivity multi-donor chimerism detection service for post-transplant engraftment analysis, capable of detecting up to 3 independent donors with sensitivity down to 0.1%; serves transplant centers and clinical laboratories.
• Targeted Variation Detection Service Custom variant detection service for any customer-defined target in the human genome, starting from rsID numbers and including reference frequency information from 5 major ancestral populations; intended for research and clinical customers.
• ScisGo HLA v6 Kit PCR-based reagent kit for phased 3-field HLA typing of all class I and class II loci in a single assay, with DNA to data in 30 hours and total DNA input as low as 10 ng; for clinical and research laboratories running their own NGS workflows on Illumina MiSeq.
• ScisGo Chimerism Kit Post-transplant chimerism testing kit for donor/recipient origin analysis in peripheral blood and marrow, offering next-generation sensitivity down to 0.1%, DNA to data in 12 hours, and detection of up to 3 donors; for clinical laboratories performing their own NGS testing.
• ScisGo Fc-FcR Kit High-resolution genotyping kit for Fc Receptor genes and IgG constant region domains, analyzing up to 384 samples in a single NGS run with DNA to data in 36 hours; for clinical and research customers studying Fc receptor and IgG variation.
• ScisCloud Software (including GeMS) Cloud-based analysis software for laboratory workflow, typing analysis, and data management, including the Genetics Management System (GeMS) for data storage and visualization of HLA allele types and KIR haplotypes; supports customers using ScisGo assays and services.

Quantifiable outcome

• Greater than 99% accuracy for DRB1 and DQB1 genotypes
• +3 more outcomes

Segments3 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature7 records

Scale indicators1 record

Recent moves6 records

Expansion highlights4 records

Direct peers

• HistoGenetics: HistoGenetics is a CLIA-certified HLA typing laboratory offering high-resolution sequencing-based HLA and KIR genotyping services. It is the most directly comparable peer, serving transplant centers and research institutions with a similar NGS-based service model.
• GenDx (Eurofins): GenDx (now part of Eurofins) provides NGS-based HLA and KIR typing reagents, kits, and software (e.g., NGSengine) to transplant labs worldwide. It directly competes with Scisco on both laboratory services and the kit/reagent side of the business.
• Omixon (now part of Eurofins): Omixon develops NGS-based HLA typing kits and analysis software (Holotype) used by transplant labs globally. It directly competes with Scisco on the HLA kit/software product line and shares a similar customer base of clinical laboratories.

Broad incumbents

• CareDx: CareDx is a leading transplant diagnostics company offering AlloSure, AlloMap, and related donor-derived cell-free DNA tests. While broader in scope, CareDx increasingly intersects with HLA typing and post-transplant monitoring, the same clinical use cases Scisco's chimerism service addresses.
• Thermo Fisher Scientific (One Lambda): One Lambda (Thermo Fisher) is a dominant supplier of HLA typing reagents, antibody detection assays, and lab software for transplant immunology. It is the most established incumbent in the histocompatibility market and competes with Scisco on kits, software, and services.
• Immucor: Immucor specializes in transfusion and transplantation diagnostics, including HLA typing reagents and instruments. Its transplant product portfolio overlaps with Scisco's HLA and chimerism services, though Immucor is a much larger, established player.
• LabCorp (Transplant Services): LabCorp is a large reference laboratory offering transplant-related testing, including HLA typing through its diagnostics division. As a broad incumbent, LabCorp serves many of the same transplant center customers as Scisco, albeit at a much larger scale.
• Quest Diagnostics: Quest Diagnostics is a major U.S. reference laboratory with transplant and immunogenetics testing capabilities. Its scale and hospital contracts make it an indirect competitor for HLA and chimerism testing volume.

Others

• Illumina: Illumina supplies the MiSeq sequencing platform that underpins Scisco's workflow and also offers HLA typing library prep products and BaseSpace software. It is both a critical technology provider and a partial competitor via its own transplant-focused offerings.

Emerging players

• PIRCHE: PIRCHE develops epitope-based HLA matching algorithms for transplant risk assessment. As an emerging software/data player in immunogenetics, PIRCHE represents a complementary or potentially competing analytic layer adjacent to Scisco's HLA typing services.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat4 records

Key risks6 records

Key highlights6 records

Customer concentration

• LinkedInlinkedin.com/company/scisco-genetics-inc

Compliance2 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Scisco Genetics