Fivos

What Fivos does

Fivos (legal entity Fivos, Inc., Delaware; headquarters at 8 Commerce Avenue, West Lebanon, NH; formerly M2S and Medstreaming, rebranded 2021) provides cloud-based clinical registry infrastructure and data services to medical professional societies and medical device manufacturers. The company's core technology is the PATHWAYS platform — a cloud-based clinical data registry solution hosted on Oracle Cloud Infrastructure that supports 14+ specialty registries covering more than 950,000 procedures across 1,000+ participating medical centers in North America. Notable technical capabilities include a Data-Driven Architecture with real-time error trapping at the point of entry, universal EMR interoperability via a data-agnostic ingestion engine, AI-assisted data abstraction achieving 98-99% Inter-Rater Reliability, and a regulatory-grade security stack (SOC 2 Type 2, HIPAA/HITECH, GovRAMP Progressing Snapshot, Patient Safety Rule compliance, with HiTrust certification expected in 2026).

Fivos serves two primary segments. For medical societies (e.g., the Society for Vascular Surgery's VQI — partnered since 2011 with 900+ centers and 1.4M+ procedures — and the Society of NeuroInterventional Surgery's NVQI-QOD with 40 centers and 25,000+ procedures), Fivos delivers subscription-based registry platform access, registry design and management services, analytics, and benchmarking. For medical device manufacturers, the company offers the Device Evaluation Portal (DEP), a tiered membership providing near real-world data access, plus custom data services including regulatory submission support (FDA, EU MDR), label expansion analysis, external control arms, post-market surveillance, and CMS compliance reporting (50+ industry reports generated annually).

The business model is primarily subscription/recurring revenue (Clinical Registry Platform Subscription, Device Data Services, DEP Membership) supplemented by professional services for end-to-end society registry management. Pricing is quote-based enterprise annual contracting with no public disclosure. Go-to-market combines direct enterprise sales (led by a VP of Industry Sales for the manufacturer segment) with a partnership-driven model in which medical societies act as channel partners expanding reach to their member hospitals. Fivos is privately held with 200+ employees across the U.S. and Egypt. In late 2023, the company divested its clinical workflow products to Picis/Harris to focus exclusively on registry and data services.

Name

Fivos

Legal name

Fivos, Inc.

Website

https://fivoshealth.com

Company type

Private

Founded year

2006

Operating status

Operating

Headcount range

101–250 employees

Short description

Fivos provides cloud-based clinical registry infrastructure and real-world evidence data services for medical societies and device manufacturers, powering 14+ specialty registries covering 950,000+ procedures across 1,000+ North American medical centers.

Ownership category

akta.pro rank

Headquarters

HQ city

West Lebanon

HQ country

United States

HQ region

North America

Offices2 records

Markets served

GTM type

B2B

Offering type

Software

Cost components

Personnel, Technology or R&D, Operations, Marketing or Sales, Infrastructure

Revenue model

1. Clinical Registry Platform Subscription: Subscription-based access to PATHWAYS registry platform for medical societies, including data collection, management, analytics, and reporting capabilities
2. Device Data Services: Custom data processing and analysis services for medical device manufacturers including regulatory submissions, label expansion support, post-market surveillance, external control arms, and FDA/CMS compliance reporting
3. Device Evaluation Portal (DEP) Membership: Tiered membership model offering varying depths of data access from device usage snapshots to in-depth analyses of patient demographics and clinical outcomes
4. Professional Services: End-to-end society registry management including design, implementation, data collection projects, industry collaboration support, and marketing communications

Pricing tiers

Go-to-market motion3 records

Distribution channels4 records

Marketing channels7 records

Core offering

Fivos operates the PATHWAYS cloud-based clinical registry platform, which underpins more than 14 specialty registries capturing over 950,000 procedures for medical societies such as the Society for Vascular Surgery (VQI) and the Society of NeuroInterventional Surgery (NVQI-QOD). For medical device manufacturers, Fivos offers the Device Evaluation Portal (DEP) and bespoke data services for regulatory submissions, post-market surveillance, label expansion, external control arms, and FDA/CMS/EU MDR reporting.

Product overview

Fivos offers a unified platform-plus-services architecture anchored by the PATHWAYS cloud-based clinical registry platform, supplemented by specialized data services for medical device manufacturers. PATHWAYS serves as the core infrastructure for 14 specialty registries (including SVS VQI and NVQI-QOD), providing data capture, management, and analytics for medical societies. The Device Evaluation Portal (DEP) sits atop the registry infrastructure, offering device manufacturers direct tiered access to real-world data for regulatory, competitive analysis, and surveillance purposes. Data Services for Device Manufacturers provides tailored evidence solutions including external control arms, label expansion, EU MDR reporting, and FDA post-approval study support. All offerings share the same underlying registry data infrastructure and data governance framework.

Differentiator

Problem solved

Functional benefit

Products and services

• PATHWAYS Platform Cloud-based clinical registry platform hosted on Oracle Cloud Infrastructure that enables data capture, management, and analytics for more than 14 specialty registries covering 950,000+ procedures, with AI-assisted data abstraction, EMR integration, and real-time error trapping. It is sold primarily to medical societies.
• Device Evaluation Portal (DEP) Direct-access portal providing medical device manufacturers with near real-time data from clinical registries through tiered membership, enabling competitive analysis, regulatory submissions, outcome tracking, and product innovation opportunities.
• Clinical Registry Solutions Custom and standardized clinical registry offerings for any medical discipline, built on the PATHWAYS platform, supporting therapeutic areas from surgical interventions to chronic disease management with deep longitudinal tracking and precise clinical variables.
• Data Services for Medical Device Manufacturers Real-world evidence and analytics services for medical device manufacturers, including label expansion support, EU MDR regulatory reports, external control arm development, FDA and post-approval study facilitation, CMS requirement data compilation, and total product lifecycle surveillance.

Quantifiable outcome

• 98-99% Inter-Rater Reliability with AI-assisted data abstraction
• +4 more outcomes

Named customers6 records

Segments3 records

Ideal customer profiles2 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

AI capability3 records

Feature6 records

Partnerships

Six partnerships are on record, tiered core and strategic.

• Carta HealthcarecoreTechnology or Integration · 2 December 2025Strategic partnership leveraging Carta Healthcare's AI-powered Lighthouse platform and hybrid intelligence approach with Fivos' PATHWAYS registry platform. Combines AI abstraction technology with clinical registry infrastructure to enhance speed, accuracy, and consistency of data submitted to national vascular registries. Helps hospitals reduce manual data abstraction burden while improving data completeness and timeliness.
• Society for Vascular Surgery (SVS)coreStrategic or Co-development PartnerLong-term partnership since 2011 where Fivos provides data infrastructure for SVS VQI registry, collecting clinical information on vascular procedures across 900+ centers in North America. SVS VQI is governed by SVS Patient Safety Organization. Fivos supports data capture, management, and analytics for quality improvement across vascular care.
• Society of NeuroInterventional Surgery (SNIS) Patient Safety OrganizationcoreStrategic or Co-development PartnerPartnership supporting NVQI-QOD registry for neurovascular quality outcomes database. Fivos PATHWAYS platform hosts the registry which has recorded 25,000+ procedures across 40 medical centers. Registry captures 100% of procedures including demographic, procedure, and post-op data for quality assurance and improvement.
• NeuroPoint Alliance (NPA)coreStrategic or Co-development PartnerNPA, established by American Association of Neurological Surgeons, partners with SNIS PSO to govern NVQI-QOD registry. NPA represents neurosurgical practices' quality care and research needs nationally, working with Fivos for data collection and analysis.
• VISION (Vascular Implant Surveillance and Interventional Outcomes Network)strategicTechnology or IntegrationPartnership linking PVI registry dataset to CMS claims data through VISION, enabling access to longitudinal outcomes extending beyond one year for enhanced regulatory and clinical evidence generation.
• Picis/HarrisstrategicOEM/ Whitelabel/ Licensing PartnerIn late 2023, Fivos transitioned workflow products to Picis/Harris, allowing Fivos to focus exclusively on core registry and data services strength.

Scale indicators14 records

Recent moves8 records

Expansion highlights5 records

Direct peers

• Health Catalyst: Health Catalyst provides a healthcare data and analytics platform with quality and registry-adjacent offerings for health systems and life sciences customers. It competes most directly with Fivos on clinical data infrastructure and quality-improvement analytics sold into hospitals and medtech.
• Premier, Inc. Premier operates the PremierConnect clinical quality and benchmarking platform used by hospitals for quality improvement initiatives analogous to Fivos's registry-based benchmarking services. Both monetize aggregated clinical data for quality and operational improvement.
• TriNetX: TriNetX runs a federated real-world data network used by life sciences customers for clinical research and regulatory-grade evidence. Its network-effects-driven model and life sciences buyer focus closely parallel Fivos's Device Evaluation Portal and RWE services.

Broad incumbents

• IQVIA: IQVIA is the largest scaled RWE and clinical research provider for life sciences, with broad capabilities across real-world data, post-market studies, and regulatory submissions. It is a much broader incumbent than Fivos but competes for the same device manufacturer RWE budgets.
• ICON plc: ICON (post-PRA Health Sciences combination) operates large-scale clinical research and real-world evidence services for medtech and pharma. It overlaps with Fivos on device RWE and post-market surveillance work, but as part of a much wider CRO portfolio.
• Flatiron Health: Flatiron Health (Roche) provides real-world oncology evidence and electronic medical record solutions used by life sciences and regulators. While oncology-focused, it is a comparable real-world evidence platform monetized into pharma/medtech for regulatory and label-expansion use cases.
• Veradigm (formerly Allscripts): Veradigm operates large-scale EHR and clinical data assets used for registries and research, including registry-style datasets for cardiology and other specialties. As an EHR incumbent, it represents a structural alternative to Fivos for societies and hospitals wanting data infrastructure from their vendor.

Emerging players

• ConcertAI: ConcertAI is a real-world evidence and AI company focused on oncology and clinical research datasets for life sciences. It targets a similar buyer (life sciences RWE, regulatory-grade evidence) but in a narrower oncology specialty.
• Aetion: Aetion provides real-world evidence analytics software used by life sciences companies and regulators for safety, efficacy, and value assessment. It is a more analytics-software-led competitor to Fivos's device manufacturer RWE services.
• COTA Healthcare: COTA curates oncology real-world data and evidence used by life sciences companies for regulatory and commercial decisions. Like Fivos, it monetizes curated clinical datasets into device and pharma buyers for evidence generation.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• LinkedInlinkedin.com/company/fivoshealth
• Xx.com/FivosHealth
• Facebookfacebook.com/FivosHealth

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Fivos