Nen

What Nen does

Nen is a Barcelona-based digital therapeutics company founded in 2022 that develops nendo, a gamified cognitive behavioral therapy (CBT) mobile application for pain management in pediatric oncology patients aged 7-12. The core platform delivers evidence-based behavioral techniques through interactive games and virtual companions to help children modulate pain, emotional regulation, and resilience during cancer treatment. A linked nendo parents companion app provides caregivers with educational content, support techniques, and tracking of their child's pain and mood progression. The company operates under a "buy one share one" social impact model where each app purchase subsidizes free access for an underserved child, distributed through the iOS App Store and Google Play.

Nen combines product-led consumer distribution with clinical evidence generation through academic and institutional partnerships. In February 2026, the company launched Proyecto ABRAZO, its first pediatric oncology clinical trial enrolling 150 patients in Puebla, Mexico, in collaboration with the University of Notre Dame, Harper Cancer Research Institute, Universidad Popular Autónoma del Estado de Puebla (UPAEP), and Una Nueva Esperanza. The product is not FDA-approved and is positioned as a support tool rather than a diagnostic or treatment device. Clinical advisors include specialists from Children's National, Weill Cornell Medicine, and Hospital Sant Joan de Déu.

The company is privately held and venture-backed, with board representation from 7WireVentures and Phs, and accelerator support from Plug and Play, CancerX, KidsX, EIT Health, Parkview Health/Matter, UNICEF Lab, and Accel-Ed. Leadership is led by founder and CEO Francesca Domenech Wuttke, PhD, a former Chief Digital Officer with 25+ years of pharmaceutical and digital health experience. Nen operates with 1-10 employees from its registered office in Sant Cugat del Vallès (Barcelona), Spain.

Name

Nen

Legal name

NEN EVIDENCE BASED SOLUTIONS, S.L.

Website

https://nen.health

Company type

Private

Founded year

2022

Operating status

Operating

Headcount range

1–10 employees

Short description

Nen is a Barcelona-based digital therapeutics company that develops nendo, a gamified cognitive behavioral therapy mobile app for pain management in pediatric oncology patients aged 7-12, distributed via app stores alongside a companion app for parents and caregivers.

Ownership category

akta.pro rank

Product category

Digital Therapeutics

akta.pro primary industry

Behavioral Health & Neurocognitive Therapeutics (Digital) (HLACANAI)

Keywords

• Pediatric pain management
• Digital therapeutics
• Cognitive behavioral therapy
• Mobile health apps
• Gamified health interventions

Headquarters

HQ city

Barcelona

HQ country

Spain

HQ region

Europe

Offices2 records

Markets served

GTM type

B2C

Offering type

Software

Cost components

Personnel, Technology or R&D, Marketing or Sales, Operations

Revenue model

1. App Sales (Buy One, Share One): Revenue generated from direct consumer app sales through iOS App Store and Google Play. The company operates a social impact model where each purchase provides free access to another child in need, effectively subsidizing access for underserved populations through commercial sales.
2. Clinical Trial Partnerships: Collaborative clinical trials with academic and clinical institutions generate clinical evidence to support product efficacy and potentially support future reimbursement or healthcare system adoption.

Pricing tiers

Go-to-market motion1 record

Distribution channels3 records

Marketing channels5 records

Core offering

Nen develops and sells nendo, a digital cognitive behavioral therapy platform delivered as a mobile app that uses gamification and behavioral techniques to help children aged 7-12 manage pain, particularly pain associated with cancer treatment. The company also offers nendo parents, a companion app providing caregivers with educational content, support techniques, and tracking of the child's pain and mood progression.

Product overview

Nen offers a pediatric digital therapeutic platform comprising two companion mobile apps: nendo and nendo parents. nendo is the core digital program designed for children aged 7-12 that delivers behavioral techniques for pain management through gamified interactive games. nendo parents is the companion app for caregivers that provides educational support, tracks the child's pain and mood progression, and reinforces adaptive coping strategies. The platform leverages cognitive behavioral therapy (CBT) techniques and is specifically designed for pediatric oncology patients to help manage pain, emotional regulation, and resilience during cancer treatment.

Differentiator

Problem solved

Functional benefit

Products and services

• nendo A digital cognitive behavioral therapy platform for children aged 7-12, primarily those with cancer, that delivers behavioral techniques through gamified interactive games and virtual companions to help manage pain, emotional regulation, and resilience.
• nendo parents A companion app linked to nendo that provides parents and caregivers with educational services, support techniques, access to the child's pain progression data, and mood tracking to support their involvement in pain management.

Quantifiable outcome

• Behavioral methods can lead to significant improvement in quality of life for children experiencing pain

Named customers1 record

Segments3 records

Ideal customer profiles2 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature4 records

Partnerships

Nine partnerships are on record, tiered core and minor.

• University of Notre DamecoreStrategic or Co-development Partner · 17 February 2026Academic research partner in Proyecto ABRAZO clinical trial, contributing to Harper Cancer Research Institute collaboration for pediatric oncology pain management research.
• Harper Cancer Research InstitutecoreStrategic or Co-development Partner · 17 February 2026Research institute collaborating on the Proyecto ABRAZO clinical trial to evaluate digital CBT platform for pain management in pediatric oncology patients.
• Universidad Popular Autónoma del Estado de Puebla (UPAEP)coreStrategic or Co-development Partner · 17 February 2026Academic partner in Mexico hosting the clinical trial enrollment site for 150 pediatric oncology patients and their caregivers in Puebla.
• Una Nueva EsperanzacoreStrategic or Co-development Partner · 17 February 2026Clinical partner in Mexico contributing to the Proyecto ABRAZO pediatric oncology clinical trial for digital therapeutic intervention.
• Plug and PlayminorGTM or Marketing PartnerSelected as portfolio company for health innovation ecosystem and acceleration support.
• UNICEF LabminorGTM or Marketing PartnerSelected for UNICEF Lab VI edition program supporting child-focused digital health innovation.
• KidsXminorGTM or Marketing PartnerSelected for 2023 KidsX Pediatric Accelerator, a program focused on accelerating pediatric digital health startups.
• EIT HealthminorGTM or Marketing PartnerSelected as semifinalist for EIT Health Catapult 2023-24, a European healthtech accelerator program.
• Parkview Health and MatterminorGTM or Marketing PartnerSelected as semifinalist for the Healthy Kids Healthy Future Pediatrics Accelerator.

Scale indicators3 records

Recent moves6 records

Expansion highlights6 records

Others

• HopeLab: Non-profit social impact organization that develops evidence-based digital tools for the health of young people, including cancer-related fatigue interventions. Others peer because HopeLab operates with a similar mission-driven, evidence-based pediatric digital health model — even though it is non-profit and not directly commercial.

Direct peers

• Akili Interactive: US-based prescription digital therapeutic company focused on cognitive/behavioral interventions, including pediatric ADHD (EndeavorRx). Direct peer because both build regulated digital therapeutics delivering cognitive/behavioral techniques to children via game-like interfaces.
• Mahana Therapeutics: Digital therapeutics company developing prescription CBT-based software for conditions including irritable bowel syndrome. Direct peer because both deliver evidence-based digital CBT through a software-as-medical-device model targeting a specific patient population.
• Limbic: Digital therapeutics company offering an AI-supported self-help platform for depression and anxiety. Direct peer because both are European-headquartered digital therapeutic platforms delivering evidence-based behavioral interventions at scale.
• Smileyscope: Develops VR-based digital interventions to reduce needle pain and anxiety in children undergoing medical procedures. Direct peer because Smileyscope targets pediatric procedural pain with non-pharmacological digital tools — same end user (children undergoing medical treatment) and same unmet need (pediatric pain management).

Emerging players

• Wysa: AI-chatbot-based mental health support app with a specific pediatric configuration and clinical partnerships. Emerging player peer because Wysa is a digital behavioral health tool that has navigated pediatric mental health regulatory pathways and payer discussions similar to what Nen must pursue.
• BehaVR: Develops VR-based digital therapeutics for mental health and chronic pain conditions. Emerging player peer because BehaVR applies immersive behavioral techniques to pain — overlapping therapeutic mechanism with Nen, but with a broader adult-leaning indication portfolio and VR delivery format.

Broad incumbents

• Pear Therapeutics (legacy / re-emerging assets): Pioneer in prescription digital therapeutics (reSET, reSET-O, Somryst) before winding down its commercial operations in 2023. Broad incumbent peer because Pear's playbook — clinical evidence generation, FDA clearance, payer reimbursement — defines the strategic pathway Nen is pursuing.
• Headspace Health: Mental health/wellness platform with a dedicated pediatric offering (Headspace for Kids) and Ginger integration. Broad incumbent peer because Headspace reaches children through digital channels with behavioral/wellness content, partially overlapping Nen's pediatric mental wellness positioning.
• Big Health: Digital therapeutics company offering Sleepio (insomnia) and Daylight (anxiety), marketed through employer/payer channels. Broad incumbent peer because Big Health has scaled CBT-based digital therapeutics commercially and demonstrates the payer/provider channel strategy Nen likely needs.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat4 records

Key risks6 records

Key highlights6 records

Customer concentration

• LinkedInlinkedin.com/company/nen-evidence-based-solutions

Compliance2 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles6 records

Funding overview

Funding rounds2 records

Investors2 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Nen