What Purolite Life Sciences does

Purolite Life Sciences, legally Purolite Corporation, is a global manufacturer of ion exchange and chromatography resins operating as a subsidiary of Ecolab Inc. Founded in 1980 and headquartered in King of Prussia, Pennsylvania with UK manufacturing operations in Wales, the company produces polymeric resin beads used to separate, purify, and extract specific elements and compounds across highly regulated industries. Its product portfolio is organized into affinity chromatography resins (the Praesto and DurA Cycle Protein A lines for monoclonal antibody purification), ion exchange chromatography resins (Praesto Jetted SP and Q), chelating resins under the Puromet brand for hydrometallurgy (antimony, bismuth, uranium, copper, cobalt), Purogold resins for gold recovery, and specialty brands such as CriticalResin (nuclear-grade), UltraClean (ultrapure water), Macronet, Purofine, PuroSorb, and Shallow Shell.

The company's core technology is built on proprietary chemistries and bead-architecture methods, including jetting technology for Protein A and ion exchange resins, Shallow Shell resin morphology for improved kinetics, and aminophosphonic/isothiouronium chelating functional groups with documented 10-20% capacity advantages over conventional resins. Purolite operates five R&D centers, nine application laboratories (including a new BPAL in Dongtan, Korea opened in April 2026), and five production facilities, supported by one of the industry's largest technically trained direct sales forces across the Americas, EMEA, APAC, and FSU.

Revenue is generated primarily through direct hardware sales of resin products to enterprise customers, supplemented by value-added services such as Field Applications Scientists, applications laboratory support, and free simulation software (PRSM). Customer segmentation spans biopharmaceutical and biotechnology manufacturers, water treatment and power generation operators, mining and hydrometallurgy firms, pharmaceutical companies, nuclear power facilities, and food & beverage/nutraceutical processors in 100+ countries. Pricing is quote-based and not publicly disclosed, and the visual branding transitioned from Purolite to Ecolab in April 2024 while the legal entity name remains unchanged.

Name

Purolite Life Sciences

Legal name

Purolite Corporation

Website

https://purolite.com

Company type

Private

Founded year

1980

Operating status

Operating

Headcount range

501–1,000 employees

Short description

Purolite Life Sciences, a subsidiary of Ecolab Inc., manufactures ion exchange and chromatography resins for biopharmaceutical purification, water treatment, mining, and nuclear customers globally through five production facilities, nine application labs, and direct enterprise sales across 100+ countries.

Ownership category

akta.pro rank

Product category

Ion Exchange and Chromatography Resin Manufacturing

NAICS

Resin, Synthetic Rubber, and Artificial and Synthetic Fibers and Filaments Manufacturing (3252), Resin and Synthetic Rubber Manufacturing (32521)

SIC

Plastic Materials, Synth Resins & Nonvulcan Elastomers (2821), Industrial Organic Chemicals (2860)

akta.pro primary industry

Ion Exchange Resins & Functional Adsorbents (IMAEAIAH)

akta.pro secondary industries

Specialty Polymers & Resins (Engineered Materials) (IMAEABAK), Bioprocess Consumables & Reagents (resins, membranes, media components, buffers) (HLAAAJAI)

Keywords

• Ion exchange resins
• Chromatography resins
• Biopharmaceutical purification
• Water treatment resins
• Metal extraction resins

Headquarters

HQ city

Llantrisant

HQ country

United Kingdom

HQ region

Europe

Offices6 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Operations, Technology or R&D, Personnel, Marketing or Sales, Infrastructure

Revenue model

1. Resin Product Sales: Sale of ion exchange resins, chromatography resins, adsorbents, and chelating resins to pharmaceutical, biotechnology, water treatment, mining, food & beverage, nuclear, and industrial customers. Products are sold directly through sales teams with technical support.

Go-to-market motion2 records

Distribution channels3 records

Marketing channels6 records

Core offering

Purolite Life Sciences develops, manufactures, and sells ion exchange resins, chromatography resins, chelating resins, and adsorbents used by industrial customers to separate, purify, and extract specific elements and compounds. Core offerings include Protein A affinity resins and ion exchange chromatography resins (Praesto, DurA Cycle A50, Jetted A50 platform) for monoclonal antibody and protein purification, Puromet chelating resins for uranium, copper, cobalt, and precious metals recovery, Purogold resins for gold recovery, and CriticalResin nuclear-grade products, supported by PRSM simulation software and field applications services.

Product overview

Ecolab Purolite Life Sciences is a global leader in resin-based separation, purification, and extraction technology, offering a comprehensive portfolio of chromatography resins and ion exchange solutions. The product portfolio centers on Purolite branded chromatography resins for biopharmaceutical purification (including Protein A affinity resins such as DurA Cycle A50, Praesto AP+ Platform, Praesto Jetted A50 variants, and Praesto 70 CH1 for specialized mAbs), IEX chromatography resins (Praesto Jetted SP and Q), and metallurgical ion exchange resins under the Puromet and Purogold brands for uranium extraction, gold recovery, and metals purification. The portfolio is organized under sub-brands including CriticalResin (nuclear-grade products), Macronet, Purofine, Puromet (hydrometallurgy), PuroSorb (adsorbents), Shallow Shell (improved kinetics), and UltraClean (ultrapure water). Supporting software tools include PRSM (Purolite Resin System Modeling) with nine calculator modules for ion exchange plant design, Affinity Resin Selector, Chromatography Column Packing Calculator, and Unit Conversion Calculator. The company also offers value-added services including Bioprocessing Applications Laboratories and Field Applications Scientists for customer technical support.

Differentiator

Problem solved

Functional benefit

Products and services

• Purolite DurA Cycle A50 Affinity Protein A chromatography resin for monoclonal antibody purification, intended for biopharmaceutical manufacturers producing mAbs at clinical and commercial scale.
• Purolite Praesto 70 CH1 Chromatography resin engineered to purify specialized monoclonal antibodies including bispecifics and antibody fragments, for biopharmaceutical manufacturers developing next-generation antibody therapeutics.
• Purolite Praesto AP+ Platform Affinity resin platform offering cost savings, high capacity, and sustainability for biopharmaceutical purification processes across mAb manufacturing.
• Purolite Praesto Jetted A50 HipH Protein A affinity resin designed for high pH elution, reducing both aggregation and host cell protein levels in monoclonal antibody production for biopharmaceutical manufacturers.
• Purolite Praesto Jetted A50 Jetted Protein A affinity resin for monoclonal antibody purification, manufactured using Purolite's proprietary jetting technology for biopharmaceutical customers.
• Purolite Praesto Jetted SP Cation exchange chromatography resin using jetting technology for protein and antibody purification in downstream bioprocessing.
• Purolite Praesto Jetted Q Anion exchange chromatography resin using jetting technology for downstream processing and protein purification in biopharmaceutical manufacturing.
• Purolite CriticalResin NRW1160 Nuclear-grade strong acid cation resin for condensate polishing and chemical volume and control system (CVCS) purification in nuclear power plants.
• Puromet MTA8000PPSO4 Ion exchange resin for fluidized bed systems in uranium extraction, optimized to maximize recovery by minimizing corrosive chloride introduction.
• Puromet MTA6002PF Gel-type strong base anion resin for extracting uranyl sulfate and carbonate complexes from leaching processes in uranium recovery operations.
• Puromet MTA5014SO4 Ion exchange resin for resin-in-pulp (RIP) technology that enables direct uranium recovery from leached pulp in mining operations.
• Puromet MTA6601 Resin-in-pulp grade resin for uranium extraction from leached pulp streams in mining and hydrometallurgical operations.
• Puromet MTS9510PF Polystyrenic macroporous aminophosphonic chelating resin for iron, copper, zinc, and fluoride removal, with superior selectivity for antimony and bismuth removal from copper electrolyte in metals processing.
• Puromet MTS9200 Polystyrenic macroporous isothiouronium chelating resin (non-regenerable) for mercury removal and precious metals recovery including gold, in metals processing and wastewater treatment applications.
• Purogold MTA5013SO4 Polystyrenic macroporous Type I strong base anion resin in sulfate form, resin-in-pulp grade, designed for gold recovery from thiosulfate leach liquors and pulps with superior mechanical strength in mining operations.
• FerrIX A33E Iron-infused adsorbent resin for arsenic removal in water treatment applications for municipal drinking water and industrial operators.

Quantifiable outcome

• 10-20% higher capacity for bismuth and antimony removal from copper electrolyte compared to conventional aminophosphonic chelating resins
• +2 more outcomes

Named customers1 record

Segments6 records

Ideal customer profiles5 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature6 records

Partnerships

One partnership is on record.

• Ecolab Inc.coreOthersPurolite Corporation operates as a subsidiary and division of Ecolab Inc., a world leader in water treatment and infection prevention. The visual branding is transitioning from Purolite to Ecolab while legal name remains Purolite Corporation. Ecolab provides continued investment to support development, production, and customer support for Purolite resin products.

Scale indicators5 records

Recent moves6 records

Expansion highlights5 records

Direct peers

• Cytiva: Cytiva (a Danaher company) is the global market leader in Protein A affinity resins (MabSelect, Fibro) and chromatography media for biopharmaceutical purification, directly competing with Purolite's Praesto and DurA Cycle product lines.
• Tosoh Bioscience: Tosoh is a leading manufacturer of Protein A affinity resins (TOYOPEARL AF-rProtein A) and ion exchange chromatography media for mAb purification, competing head-to-head with Purolite's Praesto AP+ and Jetted A50 platforms.
• Merck MilliporeSigma: Merck's Life Science division sells Eshmuno chromatography resins and a full bioprocessing consumables portfolio (mixed with filters, single-use systems) directly competing with Purolite in biopharma purification and offering bundled solutions Purolite cannot match.
• Repligen: Repligen offers OPUS pre-packed chromatography columns and is expanding into affinity resins, directly competing with Purolite's chromatography resin business while also serving as a downstream channel partner for resin suppliers.
• Bio-Rad Laboratories: Bio-Rad's Life Science segment manufactures UNOsphere and Nuvia ion exchange and affinity chromatography resins for bioprocessing, directly comparable to Purolite's Praesto and Puromet product families.
• Sartorius: Sartorius (following the BIA Separations acquisition) sells CIMmultus monolithic chromatography columns and bioprocessing consumables, competing with Purolite in downstream purification for biopharmaceutical manufacturing.
• DuPont Water Solutions: DuPont (formerly Dow Chemical) sells AmberLite, AMBERJET, and DOWEX ion exchange resins for industrial water treatment and power generation, the closest direct competitor to Purolite's industrial ion exchange portfolio.
• Lanxess: Lanxess Lewatit ion exchange resins serve water treatment, food & beverage, and industrial applications across global markets, providing direct competition with Purolite's MonoPlus, MonoPlus S, and standard resin lines.
• Mitsubishi Chemical (Organo): Mitsubishi Chemical's Diaion and Sepabeads ion exchange and adsorbent resins serve power generation, electronics ultrapure water, and pharmaceutical markets globally, comparable to Purolite's UltraClean and CriticalResin brands.

Emerging players

• Sunresin New Materials: Sunresin is a rapidly growing Chinese manufacturer of ion exchange, chelating, and chromatography resins targeting pharmaceutical, food, and hydrometallurgy markets globally, emerging as a cost-competitive alternative to Purolite in Asia and emerging markets.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks5 records

Key highlights7 records

Customer concentration

• Facebookfacebook.com/purolitecorporation
• LinkedInlinkedin.com/company/purolite-life-sciences

Compliance2 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles2 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Purolite Life Sciences