What Brymill Cryogenic Systems does

Brymill Cryogenic Systems is a privately held, family-owned manufacturer of hand-held liquid nitrogen (LN2) cryosurgical and cryospray devices, headquartered and producing out of a single facility in Ellington, Connecticut. Founded in 1966, the company has operated continuously for nearly six decades and self-identifies as the world leader in its narrow product category. Its portfolio centers on the Cry-Ac® and Cry-Ac®-3 dispensers (500ml and 300ml capacities) and the compact CRY-BABY® variant, complemented by closed probes (mini, conical, ball, flat), open-spray accessories (apertures, extensions, cryochambers, adapters), LN2 storage dewars, withdrawal devices, and ancillary consumables such as Cryo-Gloves™ and the Cryotote carrying case. Distinct industrial (CRYOGUN, MINI-CRYOGUN) and veterinary configurations extend the same hand-held platform to non-medical users.

The core technology is mechanical-thermal rather than digital: stainless-steel and brass construction with Delrin bases, a patented Safety Auto-vent that releases pressure during cap removal, a fingertip trigger for controlled LN2 application, and consistent operating-pressure delivery via a streamlined relief valve. Brymill supports its devices with a three-year equipment warranty (twelve months on certain accessories) and a certified repair-center network for post-sale service. There is no evidence of embedded electronics, sensors, connectivity, or AI/ML components in the product set.

Brymill's commercial model is a hybrid of one-time capital-equipment sales, consumables/accessory sales, and a global authorized-distributor channel with direct contact funnels reserved for the United States, United Kingdom, and Europe. Pricing is not publicly disclosed and is routed through distributors; a trade-in program for older units is operated by a named contact. Customer end-markets include dermatology and Mohs-surgery practices, primary-care and outpatient clinics, veterinary clinics, and industrial freezing users, with marketing conducted via the company website, tradeshows, residency programs, and virtual in-service training. The company has no disclosed funding rounds, no institutional ownership, no public ticker, and no reported revenue, and it operates with 11-50 employees.

Name

Brymill Cryogenic Systems

Legal name

Brymill Cryogenic Systems

Website

https://brymill.com

Company type

Private

Founded year

1966

Operating status

Operating

Headcount range

11–50 employees

Short description

Brymill Cryogenic Systems is a family-owned, Ellington, Connecticut–based manufacturer, founded in 1966, of hand-held liquid nitrogen cryosurgical and cryospray devices — chiefly the Cry-Ac® line and CRY-BABY® — serving dermatologists, veterinarians, and industrial users globally through distributors and direct channels.

Ownership category

akta.pro rank

Product category

Medical Cryosurgical Equipment

NAICS

Surgical Appliance and Supplies Manufacturing (339113)

SIC

Surgical & Medical Instruments & Apparatus (3841)

akta.pro primary industry

Sample Preparation, Storage & Cryogenics (Freezers, Cryovials, Cryostats) (HLAGAIAJ)

Keywords

• Cryosurgical equipment
• Liquid nitrogen dispensers
• Dermatology cryosurgery
• Veterinary cryosurgery
• Cryogenic storage dewars

Headquarters

HQ city

Ellington

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Supply Chain, Personnel, Operations, Technology or R&D, Marketing or Sales, Infrastructure

Revenue model

1. Medical Cryosurgical Equipment Sales: Brymill generates revenue through the manufacture and sale of hand-held liquid nitrogen cryosurgical devices, including Cry-Ac®, Cry-Ac®-3, and CRY-BABY® units. Equipment sales typically includes a 3-year warranty.
2. Accessories and Consumables: Sale of supporting products including cryosurgical probes (mini, conical, ball, flat), apertures, spray extensions, cryochambers, LN2 storage dewars, withdrawal devices, and accessories like Cryo-Gloves™ and Cryo Tweezers.
3. Industrial and Veterinary Units: Separate product lines for industrial applications (CRYOGUN and MINI-CRYOGUN) and veterinary uses.

Go-to-market motion2 records

Distribution channels3 records

Marketing channels5 records

Core offering

Brymill Cryogenic Systems manufactures hand-held liquid nitrogen cryosurgical and cryospray devices—including the Cry-Ac®, Cry-Ac®-3, and CRY-BABY® dispensers—together with closed probes, open spray accessories, LN2 storage and withdrawal equipment, industrial and veterinary CRYOGUN units, and protective accessories such as Cryo-Gloves™ and Cryo Tweezers. Equipment is engineered for precise, controlled cryogen delivery in dermatology, general medical surgery, veterinary, Mohs surgery, and industrial freezing applications, and is backed by 3-year warranties on main devices and a global distributor and certified repair network.

Product overview

Brymill Cryogenic Systems is a family-owned manufacturer of hand-held liquid nitrogen cryosurgical and cryospray equipment based in Ellington, Connecticut, operating since 1966. The product portfolio centers on the Cry-Ac® and Cry-Ac®-3 flagship dispensers (available in 500ml and 300ml capacities) complemented by the compact CRY-BABY® model. The offering is organized around four equipment categories: (1) closed probes (mini, conical, ball, flat) for contact freezing applications; (2) open spray accessories (apertures, extensions, cryochambers, adapters) for spray-based treatments; (3) LN2 handling equipment (withdrawal devices, tubes, filters, storage dewars ranging 5L-50L with 3-year warranty); and (4) accessories (Cryo-Gloves™, Cryo Tweezers, Cryoplate, Cryotote carrying case). Specialized versions include industrial and veterinary CRYOGUN units, with three-year warranties on main devices and 12-month warranties on accessories. All Brymill products are designed for medical cryosurgery applications including dermatology, oncology, and general surgical procedures, as well as veterinary use.

Differentiator

Problem solved

Functional benefit

Brands

• Cry-Ac®: Industry gold standard hand-held liquid nitrogen cryosurgical device, available in 500ml (B-700) and 300ml (B-800) capacities.
• Cry-Ac®-3
• CRY-BABY®
• CRYOGUN
• MINI-CRYOGUN
• Cryo-Gloves™

Products and services

• Cry-Ac® & Cry-Ac®-3 Liquid Nitrogen Dispensers Hand-held liquid nitrogen cryosurgical dispensers available in 500ml (B-700) and 300ml (B-800) capacities, featuring fingertip trigger control, patented Safety Auto-vent, stainless steel and brass construction, and a three-year warranty, used by physicians, NPs, PAs, and veterinarians.
• CRY-BABY® Compact LN2 Dispenser Compact version of the Cry-Ac® redesigned for improved handling and portability, offering the same reliability and precision in a smaller unit ideal for practitioners using smaller volumes of liquid nitrogen.
• Cryosurgical Closed Probes (Mini, Conical, Ball, Flat) Industry-leading closed probes for precise cryosurgical contact treatment, including mini probes for small areas and eyelid margins, conical probes for larger surface areas, ball probes for dome-like symmetrical freezing, and flat probes for deeper, quicker freezing.
• Cryosurgical Open Sprays (Apertures, Spray Extensions, Cryochambers, Adapters) Open-spray accessory line including apertures in various sizes, bent and straight spray extensions with 360° rotation, cryochambers for confined spray application, back vent adapters, angle adapters, malleable extensions, and luer lock adapters for disposable needles.
• LN2 Withdrawal Equipment (Withdrawal Device, Withdrawal Tube, Filters) Equipment for extracting liquid nitrogen from dewars, including a permanent withdrawal device with faucet-like on/off control for filling multiple units, a removable withdrawal tube for single-unit filling, and replacement filters, backed by a 12-month warranty.
• LN2 Storage Dewars (5L–50L, including LongLast 20L) Liquid nitrogen storage dewars in 5L to 50L capacities with static holding times ranging from 4–5 weeks to 14–17 weeks, including the LongLast 20L model with a 220-day holding time, plus dewar cap replacements and roller bases, backed by a 3-year warranty.
• Cryo-Gloves™ Protective Cryogenic Gloves Protective cryogenic gloves measuring 14–15 inches up to mid-arm, designed for working in hazardous ultra-cold environments; available in small (size 8), medium (size 9), and large (size 10).
• Cryo Tweezers Precision tweezers for localized skin tag treatment, providing controlled and accurate freezing of individual lesions.
• Cryoplate Focused Freezing Plate Transparent lexan plate with four conical openings (4mm, 7mm, 9mm, and 12mm) for use with Brymill apertures to deliver more focused localized freezing while protecting sensitive areas such as eyes.
• Cryotote Carrying Case for Cry-Ac® Units Durable nylon carrying bag with interior accessory pocket and shoulder strap for safely transporting Cry-Ac® or Cry-Ac®-3 units offsite.
• Industrial Units (CRYOGUN and MINI-CRYOGUN) Industrial-grade CRYOGUN units designed for industrial applications requiring hand-held liquid nitrogen delivery, distinct from medical/veterinary versions.
• Veterinary Units (CRYOGUN and MINI-CRYOGUN) CRYOGUN units designed for veterinary applications, utilizing the same liquid nitrogen cryosurgical technology adapted for animal healthcare settings.
• Starter Package Options Pre-configured starter packages that bundle essential Brymill cryosurgical products for practitioners new to the technology.

Quantifiable outcome

• 3-year warranty on main cryosurgical devices
• +1 more outcomes

Named customers5 records

Segments4 records

Ideal customer profiles4 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature7 records

Partnerships

One partnership is on record.

• Global DistributorscoreChannel Partner/ Reseller/ DistributorBrymill has established a network of authorized distributors worldwide who market and sell Brymill cryosurgical products in their respective regions. Distributors have access to product training, marketing support, and repair center certification.

Scale indicators3 records

Recent moves6 records

Expansion highlights5 records

Direct peers

• Cortex Technology: Danish manufacturer of cryosurgery and medical equipment, including hand-held liquid nitrogen spray devices for dermatology. Closest direct competitor to Brymill's Cry-Ac® line in Europe and globally.
• Wallach Surgical Devices: US-based manufacturer of office-based surgical devices including cryosurgery generators and hand-held probes used in dermatology and women's health. Directly competes with Brymill in the physician-office cryosurgery market.
• MedGyn Products: US manufacturer of gynecological medical devices including cryosurgery systems for cervical and gynecological cryotherapy. Overlaps with Brymill's clinical cryosurgery use cases, particularly in outpatient women's health settings.
• Elmed: German medical device manufacturer producing electrosurgery and cryosurgery equipment for dermatology and surgical applications. Competes head-to-head with Brymill in hand-held cryosurgical device categories.
• Genicon: US manufacturer of single-use and reusable surgical instruments including cryosurgery devices for office-based procedures. Comparable to Brymill in scale and customer base, with overlapping distribution into dermatology and primary care.

Broad incumbents

• CooperSurgical: Large US-based women's health and reproductive medical device company that offers cryosurgery systems as part of a broader portfolio. Overlaps with Brymill's clinical cryosurgery products but as part of a much wider device franchise.
• Apyx Medical (formerly Bovie Medical): US medical device company offering electrosurgical and cryosurgical technologies to surgeons and dermatologists. Cryo-based offerings overlap with Brymill's medical use cases though the company is much broader and publicly listed.
• Mettler Electronics: US manufacturer of therapeutic and medical electronic devices including cryotherapy equipment. Adjacent rather than directly overlapping, serving physical therapy and clinical cryotherapy use cases.
• Chart Industries: Major US manufacturer of industrial cryogenic equipment including LN2 storage dewars and distribution systems. Overlaps with Brymill's LN2 storage dewar and withdrawal device product line, though Chart serves industrial-scale customers.

Emerging players

• CryoConcepts: Smaller US player focused on portable cryotherapy and cryosurgery products. Targets similar clinical end-users as Brymill but with narrower product depth, representing an emerging alternative in portable cryo delivery.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat4 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/BrymillCryo
• Facebookfacebook.com/BrymillCryogenicSystems
• LinkedInlinkedin.com/company/brymill-cryogenic-systems

Revenue estimate

Valuation estimate

Number of profiles

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Brymill Cryogenic Systems