CryoConcepts
CryoConcepts is a privately held cryosurgery technology company that designs, manufactures, and distributes FDA-cleared portable cryosurgical devices (Histofreezer, CryoLab, CryOmega) and OTC consumer kits across medical, aesthetics, veterinary, and direct-to-consumer channels in 44+ countries.
- Company typePrivate
- Founded2010
- HeadquartersBethlehem, United States
- Headcount11–50
- GTM typeB2B and B2C
- OfferingHardware or Manufacturing
What CryoConcepts does
CryoConcepts LP is a privately held cryosurgery and cryotherapy technology company founded around 2010 and headquartered in Easton, Pennsylvania, led by Founder and CEO Sam Niedbala. The company designs, manufactures, and distributes a portfolio of portable and desk-top cryosurgical devices — most notably the Histofreezer, Histofreezer 2.0, Histofreezer FLEX, CryoLab, CryOmega, and CryoClear lines — that use cryogens (dimethyl ether/propane/isobutane, nitrous oxide, or CO2) and patented flow-control technology to freeze and remove benign skin lesions. Products are FDA-cleared for nine indications including common warts, plantar warts, molluscum contagiosum, skin tags, actinic keratosis, lentigo, seborrheic keratosis, and condyloma acuminata, and the portfolio is fully exempted from the EPA AIM Act HFC regulations effective January 2025.
CryoConcepts serves four horizontal customer segments through a dual-channel go-to-market model. Professional medical, aesthetics, and veterinary devices are sold exclusively through authorized medical/surgical distributors — including Henry Schein Arcona, Galen Limited, EBOS Group, BSN Medical, Hospithera, and Paladin Labs — reaching primary care, dermatology, podiatry, ob/gyn, internal medicine, medical-spa, and small-animal veterinary practices in 44+ countries. The Histofreezer brand, originally launched in 1991 by current management, was reacquired from OraSure Technologies in 2019. CryoConcepts also sells OTC consumer products (Skin Clinic Skin Tag Remover, Skin Clinic Ultimate, and Skin Clinic Advanced Wart Remover) direct-to-consumer via Amazon and the company website, marking a deliberate expansion into the at-home treatment market.
The business model is a hybrid hardware-plus-consumables structure: clinicians purchase the device (one-time hardware sale) and generate recurring revenue for CryoConcepts through replacement applicators, cones, cartridges, and refills. Aesthetic customers additionally purchase serums (TrichoCyte, Rapid Numb, Rapid Restore MD, Rejuvenate MD) used with CryoTouch and CryoTouch MD devices. The company emphasizes clinical validation (93.4% effectiveness in published studies), environmental compliance (EPA Safer Choice certification on Histofreezer 2.0, recyclable returnable canisters), and pricing advantages versus liquid-nitrogen-based cryosurgery. No funding rounds are disclosed, suggesting operations-funded or founder-financed growth, and no revenue or headcount figures are publicly reported.
CryoConcepts firmographics
Firmographics- Name
- CryoConcepts
- Legal name
- CryoConcepts LP
- Website
- https://cryoconcepts.com
- Company type
- Private
- Founded year
- 2010
- Operating status
- Operating
- Headcount range
- 11–50 employees
- Short description
- CryoConcepts is a privately held cryosurgery technology company that designs, manufactures, and distributes FDA-cleared portable cryosurgical devices (Histofreezer, CryoLab, CryOmega) and OTC consumer kits across medical, aesthetics, veterinary, and direct-to-consumer channels in 44+ countries.
- Ownership category
- akta.pro rank
CryoConcepts industry classification
Industry- Product category
- Cryosurgical Devices
- NAICS
- Electromedical and Electrotherapeutic Apparatus Manufacturing (334510), Surgical Appliance and Supplies Manufacturing (339113), Medical Equipment and Supplies Manufacturing (3391)
- SIC
- Surgical & Medical Instruments & Apparatus (3841), Perfumes, Cosmetics & Other Toilet Preparations (2844)
- akta.pro primary industry
- Cryotherapy Services (HSADAKAE)
- akta.pro secondary industries
- First Aid & Wound Care (Bandages, Dressings, Antiseptics, Burn Care) (CRADAMAB), Cryopreservation, Biobanking & Cell Banking (Cord/Adipose/MSC) (HLAMANAJ)
Keywords
Where CryoConcepts is headquartered
LocationHeadquarters
- HQ city
- Bethlehem
- HQ country
- United States
- HQ region
- North America
Offices1 record
Markets served
CryoConcepts business model
Business model- GTM type
- B2B and B2C
- Offering type
- Hardware or Manufacturing
- Cost components
- Personnel, Operations, Technology or R&D, Marketing or Sales, Supply Chain
Revenue model
- Professional Cryosurgery Devices: Sale of cryosurgical devices (Histofreezer, Histofreezer 2.0, Histofreezer FLEX, CryOmega, CryoLab) to medical, veterinary, and aesthetics professionals through authorized distributor network. One-time hardware purchase with recurring consumables (applicator buds, cones, replacement canisters).
- OTC Consumer Products: Sale of over-the-counter cryotherapy products (Skin Clinic line) directly to consumers via e-commerce platforms including Amazon. One-time purchase of treatment kits.
- Consumables and Accessories: Recurring revenue from replacement applicators, cones, cartridges, and serums for professional and consumer devices.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| One time/ perpetual license | Multi-year contract | Histofreezer 40T1C - 2mm Specialty Kit |
| One time/ perpetual license | Multi-year contract | Histofreezer 36F1C - 5mm Specialty Kit |
| One time/ perpetual license | Multi-year contract | Histofreezer 36M1C - Starter Kit |
| One time/ perpetual license | Multi-year contract | Histofreezer 60M2C+10 Value Kit |
| One time/ perpetual license | Multi-year contract | Histofreezer FLEX 50SM Mixed Kit |
| One time/ perpetual license | Multi-year contract | Histofreezer FLEX 80SM Mixed Kit |
| Unit Pricing | Pay-as-you-go | Histofreezer FLEX 240LR Replacement Kit |
| One time/ perpetual license | Pay-as-you-go | Skin Clinic Skin Tag Remover OTC Kit |
Go-to-market motion3 records
Distribution channels4 records
Marketing channels7 records
CryoConcepts product offering
Product offeringCore offering
CryoConcepts designs, manufactures, and distributes portable cryosurgical and cryotherapy devices for the medical, aesthetics, veterinary, and over-the-counter consumer markets. Its portfolio includes the Histofreezer, CryoLab, CryOmega, CryoClear, and CryoTouch product lines used to treat benign skin lesions, remove skin tags and warts, and deliver cryo-facial and carboxy therapy treatments. The company sells professional devices through authorized medical/surgical distributors in 44+ countries and OTC consumer kits through e-commerce channels.
Product overview
CryoConcepts is a cryosurgery and cryotherapy technology company offering a comprehensive portfolio of portable cryosurgical devices and systems across Medical, Aesthetics, Veterinary, and OTC/consumer market segments. The professional medical line includes Histofreezer (original and 2.0 versions), Histofreezer Flex, Histofreezer STAT, CryoLab Medical, CryoClear, and CryOmega devices for treating skin lesions. The aesthetics division offers CryoLab Aesthetics, CryoTouch, CryoTouch MD, and CryoGlobe for facial treatments and skin rejuvenation via topical carboxy therapy. Veterinary products include CryoLab Vet and CryOmega Vet variants. The OTC consumer line features Skin Clinic-branded at-home skin tag and wart removers. Supporting products include TrichoCyte for hair restoration, Rapid Numb numbing formulas, and Rapid Restore MD post-treatment serums. CryoConcepts ships to customers in over 44 countries with over 80 years of collective experience.
Differentiator
Problem solved
Functional benefit
Brands
- Histofreezer: Portable cryosurgical system for treating nine different types of skin lesions including common warts, plantar warts, genital warts, and other benign skin lesions. FDA-cleared for medical professionals.
- Histofreezer 2.0
- Histofreezer FLEX
- CryoLab Medical
- CryOmega
- CryoClear
- CryoLab Aesthetics
- CryoTouch
- CryoTouch MD
- CryoGlobe
- CryoLab Vet
- CryOmega Vet Dual Delivery
- CryOmega Vet
- Skin Clinic
- TrichoCyte
- Rapid Numb
Products and services
- Histofreezer 2.0 Enhanced portable cryosurgical system for medical professionals treating benign skin lesions and warts. Reaches -76°C with instant freezing technology, EPA Safer Choice certified, FDA-cleared, and includes a pre-paid canister return recycling program.
- Histofreezer (Original) Original portable cryosurgical system reaching -55°C using dimethyl ether/propane/isobutane cryogen and foam bud applicators. FDA-cleared for 9 indications including common warts, plantar warts, genital warts, skin tags, and actinic keratosis.
- Histofreezer FLEX Revolutionary portable cryosurgical device for medical professionals. Works with buds or cones, delivers colder environmentally-friendly cryogen via patented flow control technology that eliminates splattering, and features a rechargeable canister.
- Histofreezer STAT Environmentally friendly portable cryosurgical system with reusable canisters, available in the Canadian market for treating skin lesions.
- CryoLab Medical High-volume desk-top cryosurgical device for medical practices featuring reliability, easy maintenance, and portability for treating skin lesions.
- CryoClear Painless cryosurgical device using carbon dioxide cryogen for treating skin tags, sun spots, and age spots in medical and aesthetic practices.
- CryOmega Multi-use disposable cryosurgical pen delivering continuous direct spray of liquid nitrous oxide at -89°C/-128°F. Provides 30-45 five-second sprays per device with pinpoint precision; available in 16g single and twin pack configurations.
- CryoLab Aesthetics Refillable cylinder cryotherapy system for aesthetic practices treating age spots, sun spots, and skin tags. Delivers over 800 treatments per cylinder with illuminated wand, pre-set protocols, and real-time gas level indicator.
- CryoTouch Advanced cryo-facial device using topical carboxy therapy with hand-held CO2 dispenser and customizable serums (Hydration, Radiance, Rejuvenate). Delivers thermal shock, oxygenation, and topical infusion for facial rejuvenation.
- CryoTouch MD
- CryoGlobe
- CryoLab Vet
- CryOmega Vet Dual Delivery
- CryOmega Vet
- Skin Clinic Ultimate Skin Tag Remover
- Skin Clinic Skin Tag Remover
- Skin Clinic Advanced Wart Remover
Quantifiable outcome
- 93.4% effectiveness rate demonstrated in clinical studies for lesion treatment
- +3 more outcomes
Companies that use CryoConcepts
Customer profileNamed customers8 records
Segments4 records
Ideal customer profiles4 records
CryoConcepts technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Feature7 records
CryoConcepts partnerships and signals
Strategic signalPartnerships
Ten partnerships are on record, tiered core and minor.
- University of ChicagocoreCryoConcepts collaborated with research partners at the University of Chicago to develop the TrichoCyte supercharged hair growth formula for the CryoTouch MD hair restoration protocol.
- SUNY New YorkcoreCryoConcepts collaborated with research partners at SUNY, New York to develop the TrichoCyte supercharged hair growth formula for the CryoTouch MD hair restoration protocol.
- Galen LimitedminorInternational distributor for CryoConcepts products covering United Kingdom, Northern Ireland, Isle of Mann, and Channel Islands.
- BSN MedicalminorInternational distributor for CryoConcepts products covering Germany, Austria, South Africa, Lesotho, Swaziland, Botswana, Namibia, Zimbabwe, and Mozambique.
- EBOS Group Pty LtdminorInternational distributor for CryoConcepts products covering Australia.
- Henry Schein Arcona Inc.minorUS authorized distributor for CryoConcepts Histofreezer products.
- Paladin LabsminorCanadian authorized distributor for CryoConcepts Histofreezer products.
- ABC Medical Inc.minorCanadian authorized distributor for CryoConcepts Histofreezer products (800-361-3558).
- Advanced Medical TechnologyminorInternational distributor covering Lebanon, Qatar, Kingdom of Bahrain, United Arab Emirates, and Libya.
- Hospithera SAminorInternational distributor covering Belgium.
Scale indicators6 records
Recent moves6 records
Expansion highlights6 records
CryoConcepts competitors and assessment
Company assessmentDirect peers
- Apyx Medical (formerly Bovie Medical): Medical device company with a Renuvion/J-Plasma portfolio and historical cryosurgery product line (Bovie-brand cryosurgical devices). Competes directly with CryoConcepts in the medical cryosurgery device market serving dermatology and surgical practices.
- Brymill Cryogenic Systems: Leading manufacturer of liquid nitrogen-based cryosurgery devices for dermatology and general practice. Competes against CryoConcepts' Histofreezer in the professional cryosurgery device category, particularly with larger clinic-based systems.
- CryoPen (H&O Equipments): Manufacturer of disposable cryosurgical pens (CryoPen) used for medical and aesthetic lesion removal. Closely competing with CryoConcepts' CryOmega disposable cryosurgical pen product.
- MedGyn Products: Specialty medical device manufacturer with a portfolio including cryosurgical devices for gynecological applications. Direct competitor in the ob/gyn cryosurgery segment where CryoConcepts serves condyloma acuminata treatment.
- Special Medical Technology: Manufacturer of portable cryosurgical devices for medical and veterinary applications. Directly comparable to CryoConcepts' Histofreezer and CryoLab product lines in the portable cryosurgery category.
Broad incumbents
- AbbVie (Allergan Aesthetics): Owns CoolSculpting, the dominant non-invasive fat reduction/cryotherapy device in the medical aesthetics market. Competes with CryoConcepts' CryoLab Aesthetics and CryoTouch product lines for medical spa capital equipment budgets.
- Bayer Consumer Health: Owns Dr. Scholl's brand including Dr. Scholl's Freeze Away, a leading OTC cryotherapy wart/skin tag removal product. Competes with CryoConcepts' Skin Clinic line in mass retail and pharmacy channels.
- CooperSurgical: Diversified medical device company with gynecology/OB focus including cryosurgery products for women's health. Competes with CryoConcepts' Histofreezer in the ob/gyn segment for treatment of condyloma acuminata.
- Church & Dwight: Major consumer packaged goods company behind Compound W, the dominant OTC wart removal brand. Competes directly with CryoConcepts' Skin Clinic Advanced Wart Remover in the consumer OTC segment with significantly larger marketing and distribution capabilities.
Regional players
- Wartner (Perrigo Company): OTC cryotherapy brand for at-home wart and skin tag removal, owned by Perrigo. Directly competes with CryoConcepts' Skin Clinic line in international consumer markets, particularly in Europe and Asia.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat5 records
Key risks6 records
Key highlights7 records
Customer concentration
CryoConcepts social profiles
Digital presenceCryoConcepts compliance and trust
Trust signalCompliance3 records
CryoConcepts financial estimates
Financial estimateRevenue estimate
Valuation estimate
CryoConcepts leadership team
Management profileNumber of profiles
Profiles1 record
CryoConcepts funding detail
Funding detailFunding overview
Funding rounds
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
CryoConcepts M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about CryoConcepts
What does CryoConcepts do?
CryoConcepts designs, manufactures, and distributes portable cryosurgical and cryotherapy devices for the medical, aesthetics, veterinary, and over-the-counter consumer markets. Its portfolio includes the Histofreezer, CryoLab, CryOmega, CryoClear, and CryoTouch product lines used to treat benign skin lesions, remove skin tags and warts, and deliver cryo-facial and carboxy therapy treatments. The company sells professional devices through authorized medical/surgical distributors in 44+ countries and OTC consumer kits through e-commerce channels.
Is CryoConcepts a public or private company?
CryoConcepts is a private company. It is classified as founder individual operated bootstrapped and is currently operating.
When was CryoConcepts founded?
CryoConcepts was founded in 2010. It employs 11 to 50 people.
Where is CryoConcepts based?
CryoConcepts is headquartered in Bethlehem, United States, in the North America region.
How does CryoConcepts make money?
Three revenue lines are on record. Professional Cryosurgery Devices are the primary driver. The others are OTC Consumer Products and consumables and Accessories.
Who are CryoConcepts's main competitors?
Direct peers on record are Apyx Medical (formerly Bovie Medical), Brymill Cryogenic Systems, CryoPen (H&O Equipments), MedGyn Products and Special Medical Technology. Broad incumbents are AbbVie (Allergan Aesthetics), Bayer Consumer Health, CooperSurgical and Church & Dwight. Wartner (Perrigo Company) is listed as a regional player.
Does CryoConcepts have an API?
No public API is recorded for CryoConcepts.
What industry is CryoConcepts in?
CryoConcepts's product category is Cryosurgical Devices. Its primary akta.pro industry code is HSADAKAE, Cryotherapy Services, with a secondary code of CRADAMAB, First Aid & Wound Care (Bandages, Dressings, Antiseptics, Burn Care). Its NAICS code is 334510 and its SIC code is 3841.