Mevion Medical Systems

What Mevion Medical Systems does

Mevion Medical Systems, Inc. is a privately-held medical device company founded in 2004 and headquartered in Littleton, Massachusetts, that develops and manufactures compact proton therapy systems for cancer treatment. Its core product platform is the MEVION S250 Series, built around a proprietary 250 MeV TriNiobium Superconducting Cyclotron and including the original MEVION S250, the gantry-based MEVION S250i with HYPERSCAN pencil beam scanning and Adaptive Aperture proton multi-leaf collimator, the multi-room MEVION S250mx, and the flagship MEVION S250-FIT — the first and only proton therapy system designed to fit inside a standard radiation therapy (LINAC) vault, paired with Leo Cancer Care's Marie® upright patient positioning platform. The systems are sold as large one-time capital purchases (e.g., $33 million for the Stanford S250-FIT) bundled with one year of service and maintenance, followed by optional multi-year service contracts at >95% guaranteed uptime; revenue is supplemented by training, implementation, and tailored financing programs. Mevion goes to market through direct enterprise sales, regional offices in EMEA (Maastricht), Asia-Pacific (Tokyo), and China (Kunshan), and channel partners such as TD Tech in Vietnam and Morveducci in Italy, targeting NCI-designated Comprehensive Cancer Centers, academic medical centers, community hospitals, and international first-in-country sites — claiming to equip 50% of leading U.S. cancer centers and capture 60% of the announced U.S. proton therapy market over the past five years.

Name

Mevion Medical Systems

Legal name

Mevion Medical Systems, Inc.

Website

https://mevion.com

Company type

Private

Founded year

2004

Operating status

Operating

Headcount range

101–250 employees

Short description

Mevion Medical Systems develops and manufactures compact proton therapy systems for cancer treatment, anchored by the MEVION S250 Series. The flagship MEVION S250-FIT is the first proton therapy system designed to fit inside a standard LINAC vault, sold to hospitals and cancer centers globally.

Ownership category

akta.pro rank

Product category

Proton Therapy Systems

NAICS

Irradiation Apparatus Manufacturing (334517), Medical Equipment and Supplies Manufacturing (3391)

SIC

Electromedical & Electrotherapeutic Apparatus (3845), Surgical & Medical Instruments & Apparatus (3841)

akta.pro primary industry

Radiation Therapy Planning & Simulation Imaging (CT Sim/MR Sim) (HLAHABAH)

akta.pro secondary industries

Reactor Instrumentation & Control (I&C) Platforms (Safety/Non-safety, Digital Upgrades) (EUAKADAH), Radiation Oncology (HLAKAFAC)

Keywords

• Compact proton therapy
• Radiation oncology systems
• Proton beam therapy
• Superconducting cyclotron
• Cancer treatment equipment

Headquarters

HQ city

Littleton

HQ country

United States

HQ region

North America

Offices4 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Technology or R&D, Supply Chain, Personnel, Marketing or Sales, Operations, Infrastructure

Revenue model

1. Proton Therapy System Hardware Sales: Large one-time capital equipment sales of the MEVION S250, MEVION S250i, MEVION S250-FIT, and MEVION S250mx systems to hospitals and cancer centers, typically requiring multi-year capital planning (e.g., the $33 million Stanford system). Includes standard 1-year service and maintenance bundled with the price.
2. Service and Maintenance Agreements: Recurring post-installation service contracts with on-site engineering, 24/7 beam availability, quarterly preventative maintenance, and 95%+ contractual uptime guarantee. Optional additional coverage with cost dependent on services and term.
3. Customized Business and Financing Programs: Tailored financial programs and proforma support for customers, varying by individual customer needs and including assistance with business planning, market analysis, and capital project development.
4. Training, Implementation, and Collaboration Services: Comprehensive training programs for physicians, therapists, dosimetrists, physicists, administrators, and hospital engineers; ramp-up and continuous improvement consulting; and long-term collaboration services for research partnerships.

Pricing tiers

Go-to-market motion3 records

Distribution channels5 records

Marketing channels11 records

Core offering

Mevion Medical Systems designs, manufactures, and installs compact single-room proton therapy systems for the treatment of cancer. Its MEVION S250 Series portfolio—built around a 250 MeV TriNiobium Superconducting Cyclotron—includes the MEVION S250, S250i, S250mx, and S250-FIT systems, which deliver Intensity-Modulated Proton Therapy (IMPT) to hospitals and cancer centers with a fraction of the footprint, cost, and energy of traditional multi-room proton facilities.

Product overview

Mevion Medical Systems offers a unified MEVION S250 Series of compact single-room proton therapy systems for cancer care, built on a common TriNiobium Superconducting Cyclotron platform. The portfolio comprises the MEVION S250 Proton Therapy System, the flagship MEVION S250i with HYPERSCAN and Adaptive Aperture, the MEVION S250mx Multi-Room Proton Therapy System, and the newest MEVION S250-FIT designed to fit into an existing LINAC vault. The S250i and S250-FIT share the HYPERSCAN pencil beam scanning platform for Intensity Modulated Proton Therapy (IMPT) and are designed to support DirectARC proton arc therapy, daily online adaptive proton therapy, and FLASH research capabilities. The S250-FIT is the first and only proton therapy system designed for installation in a standard radiation therapy vault, dramatically reducing infrastructure costs and complexity.

Differentiator

Problem solved

Functional benefit

Brands

• MEVION S250 Series: The overarching product family of compact proton therapy systems, encompassing the S250, S250i, S250-FIT, and S250mx models.
• MEVION S250
• MEVION S250i
• MEVION S250-FIT
• MEVION S250mx
• HYPERSCAN
• Adaptive Aperture

Products and services

• MEVION S250-FIT Proton Therapy System The first and only full proton therapy system designed to fit inside an existing standard LINAC vault (as small as ~110 m² / 1,200 sq ft), featuring HYPERSCAN Pencil Beam Scanning for IMPT, large-bore diagnostic CT at isocenter for IGRT and adaptive therapy, AI-driven treatment planning, and FLASH research readiness. Targets hospitals seeking to add proton therapy without building dedicated proton bunkers.
• MEVION S250i Proton Therapy System Gantry-based compact proton therapy system with a 190-degree rotating gantry and gantry-mounted proton accelerator, integrating HYPERSCAN pencil beam scanning and Adaptive Aperture pMLC for high-quality IMPT treatments at hyper-speed with 1–3 mm collimated spot sizes for 0–32 cm depth range. Used by leading cancer centers for adult and pediatric tumors.
• MEVION S250 Proton Therapy System The world's first compact single-room proton therapy system, utilizing a 250 MeV TriNiobium Superconducting Cyclotron with a Direct Dose beam line design. Pioneered Mevion's compact proton therapy approach with reduced footprint, lower capital costs, and clinical capabilities comparable to conventional LINACs.
• MEVION S250mx Multi-Room Proton Therapy System Mevion's multi-room proton therapy solution that extends the compact single-room architecture to support treatment of multiple rooms in parallel or in series, without disrupting existing clinical services.
• Mevion Service and Maintenance Agreements Recurring post-installation service contracts with on-site engineering, 24/7 beam availability, quarterly preventative maintenance, and 95%+ contractual uptime guarantee. Optional additional coverage with cost dependent on services and term selected.

Quantifiable outcome

• 80% lower capital cost vs. traditional proton therapy systems
• +9 more outcomes

Named customers16 records

Segments4 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration18 records

AI capability4 records

Feature8 records

Partnerships

17 partnerships are on record, tiered flagship — core technology integration for the mevion s250-fit platform, flagship — primary treatment planning and oncology information system partner, supporting — architectural design for the stanford s250-fit installation, supporting — radiation shielding door systems for stanford, core — exclusive distributor for the vietnamese market, flagship — first proton therapy site in vietnam, core — turnkey construction partner for the pascale (naples) project, flagship — first proton therapy center in southern italy, flagship — first s250-fit clinical site and clinical validation partner, supporting — construction and shielding partners for nebraska medicine fit integration, core — industry association partner, core — particle therapy cooperative group partner, core — flagship industry society partner, core — medical physics professional society partner, core — european radiation oncology society partner, core — research and clinical collaboration partner (patient registry) and supporting — multi-vendor clinical interoperability ecosystem.

• Leo Cancer Careflagship — core technology integration for the mevion s250-fit platformStrategic or Co-development Partner · 4 June 2026Leo Cancer Care's Marie® upright patient positioning and integrated diagnostic CT imaging system is paired with the MEVION S250-FIT, enabling 360-degree patient rotation and removing the need for a rotating gantry. The Marie® platform is central to the FIT architecture and is co-deployed with Mevion at Stanford, Pascale, Tam Anh, and other FIT sites.
• RaySearch Laboratoriesflagship — primary treatment planning and oncology information system partnerTechnology or Integration · 4 June 2026RaySearch provides the RayStation® treatment planning system (with HYPERSCAN, Adaptive Aperture, DirectARC, and multi-criteria optimization) and the RayCare® oncology information system. RayStation powers the S250-FIT systems at Stanford, Tam Anh, and Pascale. Some proprietary features of HYPERSCAN with Adaptive Aperture are only available on RayStation.
• Stantecsupporting — architectural design for the stanford s250-fit installationImplementation/ SI/ Consulting Partner · 4 June 2026Stantec provided architectural design for the Stanford Medicine Cancer Center S250-FIT installation, supporting the fit-out of a conventional 110 m² (1,200 sq ft) LINAC vault into a proton therapy vault.
• NELCOsupporting — radiation shielding door systems for stanfordImplementation/ SI/ Consulting Partner · 4 June 2026NELCO provided radiation shielding door systems for the Stanford Medicine Cancer Center S250-FIT installation.
• TD Tech Company (Toan Dien Medical Technology Company Limited)core — exclusive distributor for the vietnamese marketChannel Partner/ Reseller/ Distributor · 26 May 2026TD Tech Company is Mevion's distributor in Vietnam with more than twenty years of experience in radiation oncology. TD Tech facilitated the Tam Anh General Hospital agreement to bring the first proton therapy system to Vietnam.
• Tam Anh General Hospital Groupflagship — first proton therapy site in vietnamStrategic or Co-development Partner · 26 May 2026Tam Anh General Hospital Group signed a definitive purchase agreement for the MEVION S250-FIT, bringing the first proton therapy system to Vietnam at its new Phu My Hung facility, expected operational by late 2027. One of Vietnam's leading private healthcare systems.
• Morveduccicore — turnkey construction partner for the pascale (naples) projectImplementation/ SI/ Consulting Partner · 17 May 2026Morveducci serves as the general contractor responsible for the design and construction of the new proton therapy center at Istituto Nazionale Tumori IRCCS Fondazione G. Pascale in Naples, Italy. Delivered as a turnkey collaboration with Mevion and Leo Cancer Care.
• Istituto Nazionale Tumori IRCCS Fondazione G. Pascaleflagship — first proton therapy center in southern italyStrategic or Co-development Partner · 17 May 2026Selected the MEVION S250-FIT through a competitive European tender to establish the first proton therapy center in Southern Italy. Turnkey project delivered with Leo Cancer Care and Morveducci.
• Stanford Medicine Cancer Center (Stanford Health Care)flagship — first s250-fit clinical site and clinical validation partnerStrategic or Co-development Partner · 7 April 2026Stanford Health Care is the world's first installation of the MEVION S250-FIT inside a conventional LINAC vault (Palo Alto), and the site of the world's first clinical proton therapy treatment on the S250-FIT (June 4, 2026). Deep clinical collaboration with Mevion.
• H&H Design-Build and Kiewitsupporting — construction and shielding partners for nebraska medicine fit integrationImplementation/ SI/ Consulting Partner · 29 September 2024H&H Design-Build and Kiewit partnered with Nebraska Medicine to integrate the MEVION S250-FIT into the Fred & Pamela Buffett Cancer Center, providing engineering, construction, and shielding expertise.
• National Association for Proton Therapy (NAPT)core — industry association partnerGTM or Marketing Partner · 1 January 2024Mevion is a partner of NAPT and is a presenting industry partner at the 2026 National Proton Conference. NAPT advances advocacy, education, and access to proton therapy.
• PTCOG / PTCOG-NAcore — particle therapy cooperative group partnerGTM or Marketing Partner · 1 January 2024Mevion is a partner of the Particle Therapy Cooperative Group (PTCOG) and PTCOG-NA, supporting research, education, and clinical collaboration in particle therapy.
• ASTRO (American Society for Radiation Oncology)core — flagship industry society partnerGTM or Marketing Partner · 1 January 2024Mevion is a partner of ASTRO and exhibits annually at the ASTRO Annual Meeting (Booth 1917 in 2024, Booth 1215 in 2025), hosting symposia and product launches.
• AAPM (American Association of Physicists in Medicine)core — medical physics professional society partnerGTM or Marketing Partner · 1 January 2024Mevion is a partner of AAPM, supporting medical physics research, education, and standards in radiation oncology.
• ESTRO (European Society for Radiotherapy & Oncology)core — european radiation oncology society partnerGTM or Marketing Partner · 1 January 2024Mevion is a partner of ESTRO and exhibits at the ESTRO Annual Congress (Booth C08:89 in 2026) to introduce the MEVION S250-FIT to the European radiation oncology community.
• Washington University / Siteman Cancer Centercore — research and clinical collaboration partner (patient registry)Strategic or Co-development Partner · 1 January 2024Washington University developed a multi-center proton patient registry and clinical education programs for Mevion customers to collect clinical data and patient treatment plans and track outcomes. The Siteman Cancer Center at Washington University School of Medicine was also the first to treat a patient on a Mevion S250 in 2013.
• VisionRT, humediQ, C-RAD, Philips, Varian, Elekta, Qfix, Siemens, Airo, BodyTom (3rd party clinical system vendors)supporting — multi-vendor clinical interoperability ecosystemTechnology or Integration · 1 January 2024Mevion integrates with leading 3rd party clinical systems including RaySearch RayStation/Philips Pinnacle/Varian Eclipse/Elekta XiO for treatment planning; RaySearch RayCare/Varian ARIA/Elekta MOSAIQ OIS; VisionRT AlignRT & GateRT, humediQ Identify, C-RAD Catalyst for motion management; Airo, BodyTom, Siemens CTVision for CT imaging; Qfix kVue, BoS Insert, BoS Headframe for immobilization.

Scale indicators10 records

Recent moves7 records

Expansion highlights5 records

Direct peers

• IBA Worldwide: Global market leader in proton therapy with the ProteusONE single-room and ProteusPLUS multi-room systems. Directly competes with Mevion's MEVION S250 Series for hospital and cancer center proton therapy procurements worldwide.
• Hitachi (Hitachi High-Tech / proton therapy business): Historically a direct proton therapy competitor (PROBEAT systems in Japan and the U.S.). The Hitachi proton therapy business has been reorganized but represents the legacy multi-room proton therapy architecture Mevion's compact S250 Series competes against.

Broad incumbents

• Varian Medical Systems (a Siemens Healthineers company): Largest radiation oncology incumbent offering the ProBeam proton therapy system alongside conventional LINACs and software. Overlaps with Mevion's customer base (cancer centers) and competes across the broader radiation oncology procurement budget.
• Elekta: Major radiation therapy and radiosurgery incumbent offering LINACs (Versa HD, Elekta Unity MR-LINAC) and the Leksell Gamma Knife. Competes with Mevion for hospital radiation oncology capital budgets and through its MOSAIQ OIS integrated into many proton centers.
• Accuray: Radiation oncology equipment maker (CyberKnife, TomoTherapy, Radixact) competing with Mevion for the same hospital capex pool, particularly at community cancer centers evaluating alternatives to proton therapy.

Emerging players

• RaySearch Laboratories: Independent treatment planning (RayStation) and oncology information system (RayCare) vendor. Key Mevion partner whose TPS powers HYPERSCAN/Adaptive Aperture/DirectARC workflows, but also a standalone vendor selling into other proton and photon therapy centers.
• Leo Cancer Care: Developer of the Marie® upright patient positioning platform that is co-deployed with Mevion's S250-FIT to enable vault-compatible proton therapy. A technology partner but with overlapping commercial activity in the upright proton therapy category.
• B dot Medical: Japanese startup developing a compact proton therapy system targeting similar single-room, lower-cost positioning to Mevion. Represents the next wave of compact proton competitors in Asia.
• TAE Life Sciences: Developer of accelerator-based boron neutron capture therapy (BNCT) systems for cancer treatment. Adjacent technology category competing for advanced radiation therapy hospital capex.
• ProNova Solutions: Compact proton therapy system developer (SC360) historically targeting the same single-room, lower-cost segment as Mevion. A relevant emerging peer in the compact proton therapy category despite its different commercial trajectory.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/MevionMedical
• YouTubeyoutube.com/channel/UCK1hmLTqYoDxJfHJCPuqQ8Q
• Facebookfacebook.com/18214828853
• LinkedInlinkedin.com/company/mevion-medical-systems
• Instagraminstagram.com/mevionmedicalsystems

Compliance7 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles7 records

Subsidiaries4 records

Funding overview

Funding rounds12 records

Investors8 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Mevion Medical Systems