Salience

What Salience does

Salience TMS Neuro Solutions, operating as Salience, is a Texas-based outpatient healthcare provider founded in 2011 and headquartered in Dallas, specializing in Transcranial Magnetic Stimulation (TMS) therapy for treatment-resistant Major Depressive Disorder (MDD), Obsessive-Compulsive Disorder (OCD), anxious depression, and—under the VA MISSION Act—veterans with depression and mood disorders. The company operates 12 clinic locations across the Dallas-Fort Worth metroplex (Allen, Carrollton, Dallas Uptown, Dallas Lake Highlands, Frisco, Plano, McKinney, Southlake) and is expanding into the Houston metro, with affiliated co-location with Salience Health behavioral health services at several sites. Salience is backed operationally by Bent Tree Health Professionals and runs a research arm through the Tim J. Kriske Research Institute in Plano, publishing peer-reviewed findings from its naturalistic outcomes database.

The core technology is FDA-cleared, non-invasive TMS therapy that delivers MRI-strength magnetic pulses to targeted brain regions—most notably the Salience Network—to restore neural pathway function without medication side effects. A standard course consists of approximately 36 outpatient sessions of about 20 minutes each over six to seven weeks, delivered via rTMS, Dorsal Medial, Theta Burst, or SAINT protocols using devices from manufacturers such as MagVenture. The company applies a multi-targeted approach for OCD that addresses both the Anti-Reward and Salience Networks.

Salience generates revenue primarily through insurance-covered treatment sessions billed to major carriers (Aetna, Cigna, BlueCross BlueShield, Optum, Magellan, Beacon, Tricare, plus Medicare/Medicaid), supplemented by self-pay courses priced at $6,000–$12,000 with financing via a SmartHealth PayCard partnership. Patient advocates handle insurance verification and prior authorization (typical approval in 4–7 business days). The go-to-motion combines a direct consumer funnel (website education, online assessment quiz, consultation requests) with a provider referral channel managed by a dedicated Director of Provider & Community Outreach and supported by recurring UTSW-accredited CME events. Salience reports a 94% patient improvement rate and 59% remission rate in depression, with 97% patient satisfaction.

Name

Salience

Legal name

Salience TMS Neuro Solutions

Website

https://salienceneuro.com

Company type

Private

Founded year

2011

Operating status

Operating

Headcount range

101–250 employees

Short description

Salience is a Dallas-based, private outpatient healthcare provider founded in 2011 that delivers FDA-cleared Transcranial Magnetic Stimulation (TMS) therapy across twelve Dallas-Fort Worth clinics and Houston for treatment-resistant depression, OCD, anxious depression, and veterans under the VA MISSION Act, with revenue sourced primarily from insurance-covered treatment courses.

Ownership category

akta.pro rank

Product category

Behavioral Health Services / Mental Health Treatment

NAICS

Offices of Physicians, Mental Health Specialists (621112)

SIC

Services-Offices & Clinics Of Doctors Of Medicine (8011)

akta.pro primary industry

Rehabilitation Therapy Equipment (PT/OT Modalities, Exercise & Balance Devices) (HLAHAMAG)

Keywords

• Transcranial magnetic stimulation
• Depression treatment services
• OCD neurostimulation
• Behavioral health clinics
• Mental health therapy

Headquarters

HQ city

Dallas

HQ country

United States

HQ region

North America

Offices11 records

Markets served

GTM type

B2C

Offering type

Services

Cost components

Personnel, Operations, Marketing or Sales, Technology or R&D, Infrastructure

Revenue model

1. TMS Therapy Treatment Sessions: Revenue generated from providing TMS therapy treatment sessions to patients. Most major insurance carriers cover TMS therapy for Major Depressive Disorder and OCD. Patients may have out-of-pocket costs depending on their insurance coverage. In-house financing available through SmartHealth PayCard partnership.
2. Insurance-Covered Healthcare Services: Services billed through insurance including Medicare/Medicaid, private insurance (Aetna, Cigna, BlueCross, Optum, Magellan, Beacon, Tricare). The company handles prior authorization and insurance coordination on behalf of patients.

Pricing tiers

Go-to-market motion2 records

Distribution channels3 records

Marketing channels8 records

Core offering

Salience provides FDA-approved Transcranial Magnetic Stimulation (TMS) therapy through a network of outpatient clinics in the Dallas-Fort Worth metroplex, targeting treatment-resistant Major Depressive Disorder, OCD, and anxious depression. The standard treatment course consists of approximately 36 sessions over 6-7 weeks using MRI-strength magnetic pulses to stimulate the brain's Salience Network. Services are delivered by board-certified psychiatrists and a 100% TMS-dedicated clinical team, with patient advocates handling insurance verification and prior authorization.

Product overview

Salience is a leading provider of TMS (Transcranial Magnetic Stimulation) therapy for the treatment of Major Depressive Disorder (MDD), OCD, and anxious depression. The company operates a network of clinic locations across the Dallas-Fort Worth metroplex, offering non-invasive, FDA-approved TMS therapy that targets the Salience Network in the brain. Services include core TMS treatment for depression, OCD, and anxious depression; specialized veterans programs; provider referral coordination; research through the Salience TMS Research Institute; and patient support including the TMS Alumni Program and insurance navigation. The treatment protocol typically involves 36 daily sessions over six to seven weeks, with insurance approvals typically processed within 4-7 business days.

Differentiator

Problem solved

Functional benefit

Products and services

• TMS Therapy
• Depression Treatment (Major Depressive Disorder)
• OCD Treatment
• Anxious Depression Treatment
• Veterans TMS Program

Quantifiable outcome

• 94% of patients report improvement in depression symptoms
• +4 more outcomes

Named customers10 records

Segments5 records

Ideal customer profiles5 records

Technology focussed No

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature4 records

Partnerships

Four partnerships are on record, tiered core.

• University of Texas Southwestern (UTSW)coreStrategic or Co-development PartnerSalience sponsors quarterly complimentary CME (Continuing Medical Education) events partnered with UTSW for accreditation. UTSW provides accreditation for educational events for medical professionals learning about TMS therapy and the latest research.
• Leading Universities and Research InstitutionscoreStrategic or Co-development PartnerSalience collaborates with leading universities and research institutions to conduct TMS therapy studies. Findings have been published in peer-reviewed journals. The company actively seeks new research opportunities and presents findings at medical conferences worldwide.
• Tim J. Kriske Research InstitutecoreStrategic or Co-development PartnerNamed research institute partnership for advancing TMS therapy research. Located in Plano, Texas, the institute collaborates with Salience TMS on research initiatives and continuing medical education.
• Salience HealthcoreOthersRelated healthcare company providing related behavioral health services including therapy services, psychiatry, and depression treatment. Salience TMS clinics are co-located with Salience Health at several locations including Frisco, Allen, and McKinney.

Scale indicators7 records

Recent moves6 records

Expansion highlights6 records

Direct peers

• Greenbrook TMS / TMS NeuroSolutions Centers: Founded as the largest multi-site TMS clinic operator in the US (formerly public via SPAC). Runs a national network of TMS centers with the same core offering (FDA-cleared TMS for MDD/OCD) and similar insurance-reimbursement economics as Salience, making it the closest comparable business model at scale.
• Neuronetics, Inc. Public (NEUO) manufacturer of the NeuroStar TMS system and operator of affiliated treatment centers. Directly comparable as a TMS-ecosystem participant combining device IP with clinic delivery of the same FDA-cleared therapy Salience delivers.
• MagVenture: Danish manufacturer of TMS coils and systems used in depression and OCD treatment; named in Salience's own partnerships as the supplier of FDA-cleared equipment. Directly comparable as a TMS technology and clinical-provision ecosystem participant.
• Brainsway Ltd. Israeli manufacturer of Deep TMS systems with FDA clearances for MDD, OCD, and smoking cessation—indications Salience also markets. Comparable as both a competitor for TMS equipment inside clinics and a proxy for the disease-area technology roadmap.
• Mindful Health Solutions: Multi-site psychiatric practice across California that delivers TMS therapy alongside medication management and psychotherapy. Closely comparable multi-clinic model focused on treatment-resistant depression in regional geographies.

Broad incumbents

• Talkiatry: Tech-enabled outpatient psychiatry group delivering in-network psychiatric care for anxiety, depression, ADHD, and substance use. Comparable as a scaled outpatient mental health provider; an upstream referring channel and increasingly a competitor for the same TRD patients.
• Cerebral: National telehealth mental health platform providing online assessment, medication management, and therapy for depression and anxiety. Comparable as a tech-enabled mental health provider targeting the same patient demand for accessible psychiatric care.
• LifeStance Health: Public (LFST) outpatient mental health platform with 600+ centers providing psychiatric, psychological, and TMS-adjacent services. Comparable as a large-scale outpatient mental health delivery model; competes for the same patient base Salience serves.
• Acadia Healthcare: Public (ACHC) operator of psychiatric hospitals, residential treatment facilities, and outpatient behavioral health programs. Comparable as a behavioral health delivery incumbent whose scale, payor contracts, and clinical infrastructure benchmark what a scaled mental health company looks like in adjacent care settings.

Emerging players

• Ellie Mental Health: Fast-growing mental health franchise operating outpatient clinics across multiple US states with therapy and psychiatry services. Comparable as an emerging multi-site behavioral health delivery model pursuing similar geographic-density strategies.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat6 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/salienceneuro

Compliance1 record

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Salience