What Synbio Technologies does

Synbio Technologies is a synthetic biology manufacturer founded in 2013 that provides custom DNA synthesis, RNA synthesis, protein expression, antibody services, gene editing, and viral packaging for academic researchers, biotechnology firms, and pharmaceutical organizations. The company operates from a primary headquarters in Suzhou, China and a US regional office in Monmouth Junction, New Jersey, serving more than 20,000 customers across 60+ countries with cumulative output exceeding 10 billion synthesized bases and 1 million+ genes.

The technology platform is built around proprietary AI-enabled systems: the NG Codon Optimization tool applies deep learning to expression characteristics for codon optimization; the Complexity Index (CI) System is engineered to handle high-GC, repetitive, and hairpin-rich sequences with a stated 100% accuracy guarantee; and the AI-TAT system predicts production cycles from a real order database. Supporting platforms include the GPS microbial gene editing system (E.coli and yeast), the Syno Ab and Geno Ab antibody design and discovery platforms, ProXpress rapid expression validation, Syno 2.0 cloning technology that is independent of restriction enzyme sites, and DNA Studio for DNA data storage with VR-based secondary structure visualization. The product portfolio spans custom gene synthesis, oligo and RNA synthesis, protein expression across mammalian, bacterial, yeast, insect, and cell-free systems, antibody discovery and production, lentivirus, adenovirus, and AAV packaging, and diagnostic probes with ISO 9001 and ISO 13485 certifications.

The business model is service-and-catalog hybrid with per-base-pair and per-unit pricing (e.g., gene fragments starting at $0.036/bp, recombinant antibody expression at $239, microbial gene editing from $1,600) and quote-based enterprise contracts. Go-to-market combines a self-serve online ordering portal (order.synbio-tech.com), a direct sales team handling custom enterprise work, event-driven demand generation at conferences such as SynBioBeta, ASGCT, PEGS Boston, and BIO International, and a flagship VWR International distribution partnership that extends reach to 180+ countries. Revenue streams include one-time service fees for gene synthesis, oligos, and catalog products alongside professional services for protein expression, antibody discovery, viral packaging, and gene editing. The company is privately held (with a prior 2017 NEEQ listing in China) and disclosed no venture funding rounds or ownership structure.

Name

Synbio Technologies

Legal name

Synbio Technologies

Website

https://synbio-tech.com

Company type

Private

Founded year

2013

Operating status

Operating

Headcount range

51–100 employees

Short description

Synbio Technologies is a synthetic biology manufacturer providing custom DNA, RNA, protein, antibody, and viral vector services to academic researchers, biotech firms, and pharmaceutical organizations across 60+ countries, leveraging AI-powered platforms for codon optimization, complex sequence handling, and turnaround prediction.

Ownership category

akta.pro rank

Product category

Synthetic Biology Services / DNA Manufacturing & Gene Synthesis

NAICS

Research and Development in Biotechnology (except Nanobiotechnology) (541714), Scientific Research and Development Services (5417), Biological Product (except Diagnostic) Manufacturing (325414)

SIC

Services-Commercial Physical & Biological Research (8731)

akta.pro primary industry

mRNA & Nucleic Acid Manufacturing Services (mRNA/saRNA/Plasmid DNA) (HLAGAGAC)

akta.pro secondary industries

Synthetic Biology & Genetic Circuit Design Platforms (pathway engineering, chassis development) (HLAAAIAD), Library & Diversity Generation Platforms (display libraries, DNA-encoded libraries for biologics, variant libraries) (HLAAAIAL), RNA Therapeutics Platforms & Design (sequence design, target ID/validation, AI/bioinformatics) (HLAAADAG), Protein Engineering & Directed Evolution Platforms (enzyme/therapeutic protein optimization) (HLAAAIAC)

Keywords

• Gene synthesis services
• Oligo synthesis services
• Protein expression services
• Antibody discovery services
• Viral vector packaging

Headquarters

HQ city

Monmouth Junction

HQ country

United States

HQ region

North America

Offices2 records

Markets served

GTM type

B2B

Offering type

Services

Cost components

Personnel, Technology or R&D, Operations, Marketing or Sales, Supply Chain, Infrastructure

Revenue model

1. Gene Synthesis Services: Custom DNA synthesis services including standard gene synthesis, long gene synthesis, gene fragments, and challenging sequence synthesis. Provides 100% accurate sequences with free codon optimization and vector build.
2. Oligo and RNA Synthesis: Custom DNA oligos, RNA oligos, siRNA/miRNA, sgRNA, modified oligos, and oligo pools synthesis services.
3. Protein Expression Services: Recombinant protein expression in mammalian, bacterial, yeast, and insect systems, including cell-free protein expression and protein purification.
4. Antibody Services: Comprehensive antibody discovery, synthesis, and production including hybridoma sequencing, recombinant antibody production, monoclonal/polyclonal preparation, and nanobody services.
5. Virus Packaging Services: Lentivirus, adenovirus, and adeno-associated virus packaging services for gene delivery research.
6. Gene Editing Services: sgRNA design, genome KO library construction, CRISPR editing services, and microbial gene editing.
7. Standard Products: Standard oligos, standard genome KO libraries, standard genome editing plasmids, protein products (recombinant streptavidin, Protein A/G/L), and therapeutic peptides sold as catalog products.

Pricing tiers

Go-to-market motion4 records

Distribution channels4 records

Marketing channels8 records

Core offering

Synbio Technologies is a synthetic biology company that designs and manufactures custom DNA, RNA, proteins, antibodies, peptides, and viral vectors on a custom services and catalog basis. Its core deliverable is high-accuracy gene synthesis (standard, long, fragment, and complex sequences) supported by AI-powered platforms (NG Codon Optimization, Complexity Index System, AI-TAT), extended downstream into protein expression (including ProXpress rapid validation), antibody discovery and production (Geno Ab, Syno Ab), and gene editing/viral packaging services.

Product overview

Synbio Technologies is a synthetic biology company offering a comprehensive molecular manufacturing platform spanning DNA, RNA, proteins, antibodies, and peptides. The core offerings include Gene Synthesis services (including Gene Synthesis – V for 2nd generation synthesis and Fragment XP Synthesis for gene fragments), Oligo Synthesis, RNA Synthesis, Protein Expression with ProXpress validation, and Antibody Services via Geno Ab and Syno Ab platforms. AI-powered platforms include NG Codon Optimization, Complexity Index (CI) System for complex sequences, and AI-TAT for turnaround prediction. Supporting infrastructure includes DNA Studio for data storage, Vector Selection services, and various library products (Variant Libraries, Genome KO Libraries). The portfolio also includes Virus Packaging (Lentivirus, Adenovirus, AAV), Peptide Synthesis including therapeutic peptides, and Diagnostic Probes & Oligos for molecular diagnostics. Standard product lines include CpG ODN, Syno Adapters/Blockers/Hybrid Capture Probes, and recombinant proteins (Streptavidin, Protein A/G/L). Recent additions include Cell-Free Expression, Nano Antibodies, and ELISA Kit Development services.

Differentiator

Problem solved

Functional benefit

Brands

• ProXpress: Protein expression platform service offering accelerated protein synthesis and high-throughput screening solutions.
• Syno
• DNA Studio
• NG Codon Optimization

Products and services

• Gene Synthesis Custom DNA synthesis service delivering 100% accurate sequences for standard and complex gene targets (including high/low GC content, repetitive sequences, and hairpins), with AI-powered complex sequence handling, free codon optimization, and free vector build. For researchers and biotech organizations needing high-fidelity synthetic genes.
• Gene Synthesis – V (2nd Generation Gene Synthesis) Second-generation gene synthesis with an upgraded workflow that integrates rapid protein expression validation directly into the synthesis pipeline, enabling an ultra-short path from sequence to validated expression. For researchers needing faster integrated gene-to-protein turnaround.
• Fragment XP Synthesis Gene fragment synthesis for fragments under 1,800 bp with AI-optimized synthesis for GC-rich, repetitive, and difficult sequences, starting at 3.6 cents per base pair. For researchers needing economical synthesis of shorter DNA fragments.
• Oligo Synthesis Custom DNA oligo synthesis covering custom oligos, diagnostic probes, NGS oligos, modified oligos, antisense oligonucleotides (ASOs), CpG ODNs, and oligo libraries. For molecular biology and diagnostics researchers.
• siRNA/miRNA Synthesis Custom siRNA and miRNA synthesis with chemically modified variants for enhanced stability and efficacy, including a Guaranteed siRNA service with at least 70% knockdown efficiency. For RNA interference researchers.
• RNA Synthesis Custom RNA oligo synthesis, RNA modification, long RNA synthesis, sgRNA synthesis via chemical synthesis and in vitro transcription, and mRNA synthesis services. For RNA research and therapeutic developers.
• sgRNA Synthesis CRISPR/Cas9 guide RNA synthesis via in vitro transcription and chemical synthesis with ready-to-use products and customizable options. For genome editing researchers.
• Protein Expression Recombinant protein expression in mammalian, bacterial, yeast, insect, and cell-free systems, with codon optimization and protein structure analysis. For researchers and biotech companies requiring custom recombinant proteins.
• ProXpress Rapid protein expression validation platform enabling accelerated expression testing and screening for fast iteration on construct design. For researchers optimizing protein expression conditions.
• Antibody Services Comprehensive antibody discovery via Geno Ab (sequencing) and Syno Ab (design) platforms, including hybridoma sequencing, recombinant antibody production, monoclonal/polyclonal preparation, humanization, nanobody services, and ELISA kit development. For therapeutic antibody developers and academic researchers.
• ELISA Kit Development Custom ELISA kit development service for accurate single-step quantification. For assay developers and diagnostics teams.
• Cell-Free Protein Expression Cell-free protein expression service delivering accelerated protein synthesis in as little as 2 hours with yields up to 3 mg/mL. For researchers needing rapid protein production without cell-based expression.
• Nanobody Discovery Service Rapid nanobody (single-domain antibody) discovery via alpaca immunization and phage display workflow. For antibody therapeutic and research programs needing small, stable antigen-binding fragments.
• Peptide Synthesis Custom peptide synthesis, peptide libraries, peptide modification, and therapeutic peptides with various modifications. For peptide research and therapeutic development.
• Therapeutic Peptides Therapeutic peptides product line offering peptide synthesis at R&D level (1 week delivery) and manufacturing level (quote-based). For pharmaceutical and biotech developers.
• Lentivirus Packaging Third-generation lentiviral packaging using HIV-1-derived vectors with optimized safety, supporting overexpression, RNAi interference, and stable cell line construction. For cell and gene therapy researchers.
• Adenovirus/AAV Packaging Viral vector packaging services for adenovirus and adeno-associated virus (AAV) for gene therapy applications. For gene therapy developers and researchers.
• Microbial Gene Editing Precision gene editing in E.coli and yeast using the proprietary GPS platform with base-pair level accuracy, multiplex site editing, and 96.6-100% knock-in success rate. For synthetic biology and industrial biotech developers.
• Mammalian Cell Gene Editing Gene editing services in mammalian cells, including sgRNA customized design, sgRNA bioinformatics analysis, human genome KO vectors, and high-throughput gene editing vectors. For genome editing researchers and therapeutic developers.
• Genome-Wide Knockout Screening Workflow End-to-end genome-wide knockout screening workflow combining sgRNA library construction, lentivirus packaging, and cell pool construction, delivering 97.93% library coverage and 8.8 distribution uniformity. For functional genomics researchers.
• Genome KO Libraries Custom and standard genome knockout libraries for human, mouse, poultry, animal, and microbial genomes, including sgRNA library cell pools for functional screening. For functional genomics researchers.
• shRNA Library Customization One-stop shRNA library construction service from design through lentivirus packaging with high coverage (>90%) and NGS verification. For RNAi screening researchers.
• Variant Libraries Synthetic CDR variant antibody libraries and error-prone scFv variant antibody libraries for antibody affinity maturation and discovery. For antibody engineers and therapeutic developers.
• Diagnostic Probes & Oligos FISH probes, qPCR probes (TaqMan/MGB), SNP probes, and modified oligos with purity up to 98% manufactured under ISO 9001 and ISO 13485 quality systems. For molecular diagnostics developers.
• Antisense Oligonucleotide (ASO) Manufacturing ASO manufacturing service with R&D-level delivery in 1 week and manufacturing level available from microgram-to-gram scale, ISO 9001 and ISO 13485 certified. For therapeutic oligonucleotide developers.
• DNA Data Storage DNA-based digital data storage solutions using the proprietary DNA Studio platform for bidirectional conversion between digital information and DNA coding. For archival storage developers and researchers.
• Plasmid DNA Preparation Plasmid DNA preparation, PCR cloning and subcloning, and site-directed mutagenesis services for molecular biology research. For researchers requiring cloning and plasmid production.
• Recombinant Streptavidin Recombinant streptavidin protein product for biotin-binding applications in assays and purification. For laboratory researchers and assay developers.
• Protein A/G/L Recombinant protein A, protein G, and protein L products for antibody purification in research and process applications. For antibody researchers and process developers.
• CpG ODN Toll-like receptor 9 (TLR9) agonists (CpG oligodeoxynucleotides) for immune response activation in vaccine development and cancer immunotherapy research. For immunology and vaccine researchers.
• Syno Capture & Adapter Reagents (Syno Adapters, Syno Blocker, Syno Hybrid Capture Probe) Catalog oligo reagents for NGS and hybridization workflows: Syno Adapters for next-generation sequencing, Syno Blocker blocking oligos to improve hybridization specificity, and Syno Hybrid Capture Probes for targeted sequencing and resequencing. For genomics and NGS researchers.

Quantifiable outcome

• 100% accurate DNA sequence synthesis guaranteed
• +3 more outcomes

Named customers3 records

Segments4 records

Ideal customer profiles4 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

AI capability7 records

Feature8 records

Partnerships

Six partnerships are on record, tiered flagship, core and minor.

• VWR InternationalflagshipChannel Partner/ Reseller/ Distributor · 26 May 2026Strategic distribution partnership making Synbio Technologies' molecular manufacturing portfolio accessible through VWR's global laboratory supply network spanning 180+ countries and 170+ years of industry experience. The partnership strengthens VWR's synthetic biology offerings while creating an integrated supply-to-application ecosystem.
• Porton AdvancedflagshipStrategic or Co-development Partner · 8 May 2023Partnership providing end-to-end solutions for cell and gene therapy clients, combining Synbio Technologies' molecular design, synthesis, and optimization expertise with Porton Advanced's CGT CDMO services from plasmid and viral vectors to cellular product GMP manufacturing.
• SnapGenecoreTechnology or Integration · 13 November 2017Partnership to streamline construct design and synthesis, integrating Synbio Technologies' synthesis services with SnapGene's molecular biology software for efficient construct design workflows.
• Twist BiosciencecoreTechnology or Integration · 11 July 2017Collaboration for supplying Long DNA to customers, combining Synbio Technologies' synthesis capabilities with Twist Bioscience's DNA writing technology.
• Fusion Antibodies LtdcoreStrategic or Co-development Partner · 1 June 2017Commercial partnership to support biologic drug development in China, combining Fusion Antibodies' antibody expertise with Synbio Technologies' synthetic biology capabilities for the Chinese market.
• ALSTEMminorChannel Partner/ Reseller/ Distributor · 17 June 2015Cooperative relations established for expanded market reach and distribution of Synbio Technologies' products and services.

Scale indicators8 records

Recent moves7 records

Expansion highlights6 records

Direct peers

• Twist Bioscience: Direct competitor in gene synthesis and DNA manufacturing; Twist operates silicon-based DNA writing at industrial scale and signed a long-DNA supply collaboration with Synbio in 2017, indicating direct overlap in target customers and product categories.
• IDT (Integrated DNA Technologies): Danaher-owned leader in custom oligonucleotides, probes, and gene synthesis — the most direct comparator on oligo and gene fragment services used by the same academic/biotech researcher base.
• GenScript: Asia-rooted global CDMO/CDS provider offering gene synthesis, protein expression, antibody services, and cell/gene therapy solutions — overlaps almost one-to-one with Synbio's service catalogue including viral vector packaging and CGT end-to-end solutions.
• Eurofins Genomics: Offers gene synthesis, oligo synthesis, and sequencing services globally; comparable commercial biological research services business targeting similar academic and biopharma researchers.
• Azenta Life Sciences (GENEWIZ): Provides gene synthesis, NGS, and molecular biology services including custom antibody and recombinant protein services — directly comparable service mix and customer base to Synbio's academic/biotech segment.

Broad incumbents

• Thermo Fisher Scientific (GeneArt): Operates GeneArt gene synthesis and protein expression as part of a much larger life sciences portfolio; broad incumbent with overlapping capabilities in molecular manufacturing serving same biopharma customers.
• Agilent Technologies (Oligo service): Broad life sciences instrumentation and services company with oligo and molecular biology offerings serving analogous diagnostic and academic customers, though Agilent is not a pure-play gene synthesis peer.

Regional players

• Bioneer: Korean oligonucleotide and molecular biology services provider — Asian-based direct competitor with overlapping oligo synthesis, gene synthesis, and molecular diagnostics probe offerings.
• Bio Basic: Asian competitor offering custom DNA/RNA oligos, gene synthesis, and protein services with cost-competitive positioning comparable to Synbio for the regional and global academic market.

Others

• Porton Advanced: Strategic CGT CDMO partner; not a direct competitor but a downstream collaborator in cell and gene therapy services — relevant ecosystem participant for understanding adjacent capacity and competitive dynamics.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat6 records

Key risks5 records

Key highlights7 records

Customer concentration

• Xx.com/synbio_tech
• YouTubeyoutube.com/@synbiotechnologies
• Facebookfacebook.com/SynbioTechnologies
• LinkedInlinkedin.com/company/synbio-technologies
• Instagraminstagram.com/synbiotech

Compliance4 records

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Synbio Technologies