Fulcrum Genomics
Fulcrum Genomics is a private, founder-owned boutique bioinformatics consulting firm that provides bespoke pipeline development, computational biology, and software engineering services to clinical diagnostics, sequencing chemistry, pharma, and population genomics clients worldwide.
- Company typePrivate
- Founded2015
- HeadquartersBoulder, United States
- Headcount11–50
- GTM typeB2B
- OfferingServices
What Fulcrum Genomics does
Fulcrum Genomics, LLC is a private, founder-owned bioinformatics consulting firm headquartered in Somerville, Massachusetts, with a fully distributed team of 14 bioinformaticians, computational biologists, and software engineers operating across the United States, Canada, and France. Founded by Tim Fennell (former Director of Bioinformatics at the Broad Institute) and Nils Homer, the firm delivers bespoke genomics data analysis, pipeline development, and software engineering services to clients ranging from single-person startups to large pharmaceutical and life science companies. Engagements are structured as Time & Materials Statements of Work under Master Services Agreements, evolving from small, well-scoped projects into ongoing reserved-capacity arrangements, with monthly invoicing and no upfront payment required.
The firm's technical core spans clinical-grade pipeline development (CAP/CLIA, 21 CFR Part 11), error-corrected sequencing (notably the DuplexSeq pipeline originally architected internally), and large-scale population genomics. Fulcrum's senior staff contributed to industry-standard open-source infrastructure, including the Workflow Description Language (WDL), the Cromwell workflow engine, and the Picard suite, providing credibility and integration advantages. Representative work includes taking Belay Diagnostics' Summit liquid biopsy assay from prototype to CAP/CLIA clinical deployment in approximately one year, independently validating Canal Biosciences' TrueLink library prep chemistry, and building the largest feline imputation reference panel (992 cats) for Darwin's Ark's citizen science population study.
Customer acquisition is sales-led and reputation-driven, with no external institutional funding, no patents, and no packaged product offering. Distribution is direct-to-client supplemented by a registered supplier presence on Scientist.com and content marketing through a Substack blog, LinkedIn, GitHub, and BlueSky. Notable client logos include Myriad Genetics, Verogen, Strata Oncology, Jumpcode Genomics, Belay Diagnostics, Canal Biosciences, Darwin's Ark, and Directed Genomics, with several relationships exceeding five years of continuous service.
Fulcrum Genomics firmographics
Firmographics- Name
- Fulcrum Genomics
- Legal name
- Fulcrum Genomics, LLC
- Website
- https://fulcrumgenomics.com
- Company type
- Private
- Founded year
- 2015
- Operating status
- Operating
- Headcount range
- 11–50 employees
- Short description
- Fulcrum Genomics is a private, founder-owned boutique bioinformatics consulting firm that provides bespoke pipeline development, computational biology, and software engineering services to clinical diagnostics, sequencing chemistry, pharma, and population genomics clients worldwide.
- Ownership category
- akta.pro rank
Fulcrum Genomics industry classification
Industry- Product category
- Bioinformatics Consulting Services
- NAICS
- Other Scientific and Technical Consulting Services (54169), Custom Computer Programming Services (541511), Scientific Research and Development Services (5417)
- SIC
- Services-Computer Programming, Data Processing, Etc. (7370), Services-Commercial Physical & Biological Research (8731)
- akta.pro primary industry
- Scientific Data Management & Data Platforms (SDMS/Data Lakehouse for R&D) (HLAGAJAC)
- akta.pro secondary industries
- Data Management, Biostatistics & Statistical Programming FSP (HLAGAOAB), Transcriptomics & Gene Expression Profiling Services (HLAGANAE), Biostatistics, Statistical Computing & Clinical Programming (SAS/R/Pipelines) (HLACAOAO)
Keywords
Where Fulcrum Genomics is headquartered
LocationHeadquarters
- HQ city
- Boulder
- HQ country
- United States
- HQ region
- North America
Offices13 records
Markets served
Fulcrum Genomics business model
Business model- GTM type
- B2B
- Offering type
- Services
- Cost components
- Personnel, Technology or R&D, Operations, Marketing or Sales, Infrastructure
Revenue model
- Professional Services - Time and Materials: Consulting engagements billed on Time and Materials basis with monthly invoicing. Clients receive effort estimates and are charged only for work performed. No upfront payment required. Engagements structured through Master Services Agreements with individual Statements of Work.
Pricing tiers
| Model | Billing | Price |
|---|---|---|
| Other | Monthly | Time and Materials consulting |
Go-to-market motion1 record
Distribution channels1 record
Marketing channels6 records
Fulcrum Genomics product offering
Product offeringCore offering
Fulcrum Genomics is a bioinformatics consulting firm that delivers bespoke genomics data analysis, NGS pipeline development, software engineering, and computational biology solutions through professional services engagements. The firm works directly with client teams on problems spanning clinical diagnostics, novel sequencing chemistry validation, population-scale genomics, and pharmaceutical R&D, embedding bioinformaticians and software engineers with clients via Statements of Work or reserved capacity arrangements. They do not sell a packaged software product; every engagement is a customized service delivering actionable insights, production pipelines, and high-quality software tailored to the client's data.
Product overview
Fulcrum Genomics is a bioinformatics consulting firm that provides expert consulting services in genomics data analysis, pipeline development, software engineering, and technology validation. Rather than offering a packaged software product, they deliver bespoke bioinformatics solutions as a service, working directly with client teams on problems spanning clinical diagnostics, sequencing chemistry development, and population genomics research. Their work is structured around consulting engagements, including Statement of Work-based projects, ad-hoc advisory, and reserved capacity arrangements.
Differentiator
Problem solved
Functional benefit
Products and services
- Bioinformatics Consulting Services
- Clinical Diagnostics Pipeline Development
- Sequencing Chemistry Validation Services
- Population Genomics Pipeline Development
- Bioinformatics Team Augmentation
Quantifiable outcome
- 99.5% genotype accuracy achieved in population genomics project
- +2 more outcomes
Companies that use Fulcrum Genomics
Customer profileNamed customers8 records
Segments5 records
Ideal customer profiles5 records
Fulcrum Genomics technology and API
TechnologyTechnology focussed Yes
API detail
- Has API
- No
- API docs
- API detail
Core technology
AI maturity
App detail
Feature3 records
Fulcrum Genomics partnerships and signals
Strategic signalPartnerships
Four partnerships are on record, tiered minor and core.
- Scantox GroupminorClint Valentine, former VP of Operations at Fulcrum Genomics (who originally architected the DuplexSeq pipeline), led the migration of DuplexSeq bioinformatics to LatchBio for Scantox Group. This represents a technology transfer/exit of the DuplexSeq pipeline intellectual property developed at Fulcrum.
- Belay DiagnosticscoreEmbedded two scientists with Belay team to move Summit liquid biopsy assay from prototype to clinical deployment, achieving CAP/CLIA certification in approximately one year.
- Canal BiosciencescoreProvided independent validation of TrueLink library prep chemistry, including cycle-resolved error analysis and chimera rate assessment ahead of commercial launch.
- Darwin's ArkcoreBuilt largest feline imputation reference panel and containerized GLIMPSE2-based imputation pipeline for 20,000+ enrolled cats in citizen science project.
Scale indicators7 records
Recent moves6 records
Expansion highlights6 records
Fulcrum Genomics competitors and assessment
Company assessmentDirect peers
- BioTeam: BioTeam is a US-based bioinformatics consulting and IT services firm supporting life science, pharma, and academic genomics. Highly comparable to Fulcrum in services-only model, scientific pedigree, and customer segments (clinical diagnostics, pharma, research institutions).
- Eagle Genomics: Eagle Genomics combines bioinformatics consulting with a platform product (e[gnosis]) for life sciences R&D. Comparable to Fulcrum in serving genomics-driven pharma and consumer goods customers and offering both custom pipeline development and broader scientific services.
- Strand Life Sciences: Strand Life Sciences provides bioinformatics software and services across clinical genomics, pharma, and research, including clinical interpretation and pipeline development. Comparable in clinical genomics consulting, Indian/global delivery model, and combined software-plus-services offering.
- Genohub: Genohub is a bioinformatics services marketplace and consultancy providing sequencing data analysis, custom pipeline development, and consulting to academic and biotech clients. Comparable in T&M-style bioinformatics services and customer base spanning startups to pharma.
Broad incumbents
- Seven Bridges (Velsera): Velsera (formerly Seven Bridges Genomics) provides a bioinformatics platform combined with professional services for clinical and translational genomics. Comparable to Fulcrum in offering pipeline development and clinical-grade NGS support, but at substantially greater scale and with proprietary platform IP.
- DNAnexus: DNAnexus operates a cloud-based bioinformatics platform serving pharma, clinical diagnostics, and research customers, with services layered on top. Directly comparable in clinical pipeline delivery and CAP/CLIA-aligned workflows, though DNAnexus is a broader platform incumbent with venture backing.
- Qiagen Digital Insights (QIAGEN Bioinformatics): QIAGEN Digital Insights offers commercial bioinformatics software (e.g., CLC, Ingenuity Pathway Analysis) plus services for clinical and pharma genomics. Comparable in providing both pipeline development and clinical interpretation, but as part of a much larger life science tools portfolio.
Others
- Seqera Labs: Seqera is the commercial steward of Nextflow and provides cloud workflow infrastructure plus services for genomics pipelines. Comparable because it serves the same bioinformatics developer community and competes for the same workflow-engineering scope of work Fulcrum delivers.
Emerging players
- Form Bio: Form Bio offers a bioinformatics platform for genomics R&D with associated services for life science customers. Comparable as a younger, venture-backed entrant providing pipeline development capabilities that overlap with Fulcrum's bespoke consulting.
- BC Platforms: BC Platforms provides a genomics and clinical data platform with associated services for pharma, biobanks, and clinical customers. Comparable in serving regulated genomics workflows and providing both software and custom bioinformatics services.
Market position
Strengths5 records
Weaknesses5 records
Competitive moat4 records
Key risks6 records
Key highlights7 records
Customer concentration
Fulcrum Genomics social profiles
Digital presenceFulcrum Genomics financial estimates
Financial estimateRevenue estimate
Valuation estimate
Fulcrum Genomics leadership team
Management profileNumber of profiles
Profiles14 records
Fulcrum Genomics funding detail
Funding detailFunding overview
Funding rounds
Investors
Funding detail is available on the Subscription and Enterprise plan.Contact sales →
Fulcrum Genomics M&A and investment
M&A and investmentM&A
Investments
M&A and investment is available on the Subscription and Enterprise plan.Contact sales →
Frequently asked questions about Fulcrum Genomics
What does Fulcrum Genomics do?
Fulcrum Genomics is a bioinformatics consulting firm that delivers bespoke genomics data analysis, NGS pipeline development, software engineering, and computational biology solutions through professional services engagements. The firm works directly with client teams on problems spanning clinical diagnostics, novel sequencing chemistry validation, population-scale genomics, and pharmaceutical R&D, embedding bioinformaticians and software engineers with clients via Statements of Work or reserved capacity arrangements. They do not sell a packaged software product; every engagement is a customized service delivering actionable insights, production pipelines, and high-quality software tailored to the client's data.
Is Fulcrum Genomics a public or private company?
Fulcrum Genomics is a private company. It is classified as founder individual operated bootstrapped and is currently operating.
When was Fulcrum Genomics founded?
Fulcrum Genomics was founded in 2015. It employs 11 to 50 people.
Where is Fulcrum Genomics based?
Fulcrum Genomics is headquartered in Boulder, United States, in the North America region.
How does Fulcrum Genomics make money?
One revenue line is on record: professional Services - Time and Materials.
Who are Fulcrum Genomics's main competitors?
Direct peers on record are BioTeam, Eagle Genomics, Strand Life Sciences and Genohub. Broad incumbents are Seven Bridges (Velsera), DNAnexus and Qiagen Digital Insights (QIAGEN Bioinformatics). Seqera Labs is listed as an others. Emerging players are Form Bio and BC Platforms.
Does Fulcrum Genomics have an API?
No public API is recorded for Fulcrum Genomics.
What industry is Fulcrum Genomics in?
Fulcrum Genomics's product category is Bioinformatics Consulting Services. Its primary akta.pro industry code is HLAGAJAC, Scientific Data Management & Data Platforms (SDMS/Data Lakehouse for R&D), with a secondary code of HLAGAOAB, Data Management, Biostatistics & Statistical Programming FSP. Its NAICS code is 54169 and its SIC code is 7370.