De Novo Software

Name

De Novo Software

Legal name

De Novo Software, LLC

Website

https://denovosoftware.com

Company type

Private

Operating status

Operating

Headcount range

1–10 employees

Ownership category

akta.pro rank

Product category

Flow Cytometry Data Analysis Software

NAICS

Software Publishers (513210), Medical and Diagnostic Laboratories (62151)

SIC

Services-Prepackaged Software (7372), Services-Medical Laboratories (8071)

akta.pro primary industry

Laboratory Informatics for Diagnostics (LIS/Middleware/Analyzer Connectivity) (HLAHAAAO)

akta.pro secondary industries

Flow Cytometry & Cellular Analysis Diagnostics (HLAHAAAF), Clinical Laboratory LIS (Core Lab/Hospital Lab) (HLACAMAA), Clinical & Translational Informatics (Clinical Data Integration/Real-World Data for R&D) (HLAGAJAF)

Keywords

• Flow cytometry software
• Image cytometry analysis
• Clinical flow cytometry
• Cell and gene therapy software
• Laboratory data analysis

Headquarters

HQ city

Glendale

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Software

Cost components

Technology or R&D, Personnel, Marketing or Sales, Operations

Revenue model

1. Software Licenses: FCS Express is sold as software licenses with various editions including Research Use Only (RUO) and IVD (In Vitro Diagnostic) versions. The software is available for purchase with different licensing options including perpetual and subscription models.

Pricing tiers

Go-to-market motion1 record

Distribution channels4 records

Marketing channels9 records

Core offering

De Novo Software develops and distributes FCS Express, a flow cytometry and image cytometry data analysis platform used by academic, clinical, and pharmaceutical researchers. The software provides analysis, statistics, graphing, and reporting for flow cytometry data and is offered in multiple editions including a Research Use Only (RUO) version for individual and academic researchers, an IVD/Clinical Edition with 21 CFR Part 11 compliance, and a Validation Ready Package for GxP-regulated cell and gene therapy research.

Product overview

De Novo Software is a life sciences software company that provides FCS Express, a comprehensive flow cytometry and image cytometry data analysis software platform. The product portfolio includes the core FCS Express platform with multiple editions: FCS Express RUO (Research Use Only) for academic and corporate R&D, FCS Express IVD (In Vitro Diagnostic) for clinical diagnostic labs with 21 CFR Part 11 compliance, and FCS Express Validation Ready Package for GxP-regulated environments. The platform offers specialized capabilities including spectral data analysis, image cytometry features, Pipelines for automated workflows, advanced transformations (t-SNE, UMAP, SPADE, PCA), and comprehensive integration with instruments and third-party tools. Additional offerings include the free FCS Express Reader for collaboration, EasyPanel integration for panel design, and Luma platform connectivity for data management. The company operates as a subsidiary of Dotmatics and serves thousands of researchers worldwide at institutions including pharmaceutical companies, clinical labs, and academic research facilities.

Differentiator

Problem solved

Functional benefit

Brands

• FCS Express: Flow cytometry data analysis software for academic research, clinical diagnostics, and validated research applications

Products and services

• FCS Express Primary flow cytometry data analysis software that enables researchers to transition from raw cytometry data to publication-ready results. Features an intuitive interface similar to Microsoft Office programs, integrated spreadsheets, real-time updating analysis, and support for flow and image cytometry workflows.
• FCS Express RUO (Research Use Only) Research Use Only edition of FCS Express intended for individual researchers, shared resource facilities, and corporate R&D groups performing non-clinical flow cytometry data analysis.
• FCS Express IVD (Clinical Edition) In Vitro Diagnostic edition of FCS Express for Clinical Diagnostic and Clinical Reference Laboratories. Includes 21 CFR Part 11 compliance features such as electronic signatures, security logging, authorizations and permissions, and system-level audit reports for regulated clinical environments.
• FCS Express Validation Ready Package Pre-validated package designed for Cell and Gene Therapy Researchers working in GxP-regulated research environments. Provides validated workflows, audit trails, and electronic signatures to meet demanding regulatory requirements.
• FCS Express Reader Free collaboration tool that allows users to view and re-analyze data that colleagues have published with a licensed copy of FCS Express. Supports both flow and image cytometry data with full analysis capabilities for published layouts.

Quantifiable outcome

• Free trial available for evaluation before purchase
• +1 more outcomes

Named customers23 records

Segments3 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration20 records

AI capability6 records

Feature7 records

Partnerships

Three partnerships are on record, tiered core.

• DotmaticscoreStrategic or Co-development PartnerDe Novo Software is a subsidiary of Dotmatics (operating as De Novo Software, LLC). Dotmatics is a scientific intelligence platform provider for AI-powered data management and workflow automation. FCS Express is marketed as part of the Dotmatics portfolio of R&D software products.
• Thermo Fisher ScientificcoreTechnology or IntegrationDe Novo Software has a continued collaboration with Thermo Scientific to support both FCS file and ACS file exports from the Attune CytPix Flow Cytometer. The partnership enables FCS Express users to work with data from Thermo Fisher instruments including the Attune Nxt Flow Cytometer and Cellomics Platform.
• EasyPanelcoreTechnology or IntegrationFCS Express integrates with EasyPanel for intelligent panel design and inventory management for flow cytometry. The integration automatically QC/validates fluorochrome reagents by comparing actual spectral signatures with expected signatures.

Scale indicators1 record

Recent moves1 record

Expansion highlights5 records

Others

• Geneious: Geneious is a Dotmatics portfolio bioinformatics platform for sequence analysis and cloning. While not a direct flow cytometry competitor, it shares the same Dotmatics distribution and serves overlapping life sciences R&D buyers.
• CellProfiler (Broad Institute): CellProfiler is an open-source image analysis platform from the Broad Institute. It is complementary rather than directly competitive, but FCS Express supports exporting ImageJ/CellProfiler-segmented images, positioning it as an ecosystem partner in image cytometry.
• LabArchives: LabArchives is a Dotmatics electronic lab notebook (ELN). It is an adjacent R&D software tool serving the same institutional buyers as FCS Express and is bundled into the Dotmatics enterprise sales motion.
• SoftGenetics: SoftGenetics, also a Dotmatics subsidiary, provides genetic analysis software for research, forensics, and healthcare. It is a portfolio-mate in the Dotmatics scientific software family serving adjacent but not directly competing workflows.

Direct peers

• FlowJo (BD Biosciences): FlowJo is the long-standing market-leading flow cytometry data analysis software, sold by BD Biosciences. It is the closest direct competitor to FCS Express, serving the same researchers, clinical labs, and pharma R&D users with comparable analysis, gating, and statistics capabilities.
• OMIQ: OMIQ is a cloud-native, AI-focused flow and mass cytometry analysis platform. It competes head-to-head with FCS Express for modern R&D teams that prefer browser-based workflows and integrated ML pipelines; notably, OMIQ is also distributed within the Dotmatics portfolio alongside De Novo Software.
• Cytobank (Beckman Coulter Life Sciences): Cytobank is a cloud-based cytometry analysis platform acquired by Beckman Coulter, offering similar high-dimensional flow cytometry analysis, gating, and clustering capabilities. It targets translational and clinical researchers with shared collaboration workflows.

Emerging players

• SpectroFlo (Cytek Biosciences): SpectroFlo is Cytek's spectral cytometry analysis software bundled with its instruments. It overlaps with FCS Express's spectral data analysis capabilities and represents an OEM-bundled alternative that competes at the instrument purchase point.
• FlowLogic: FlowLogic is a flow cytometry analysis platform from AI4dx targeting clinical and research users with intuitive workflows. It competes with FCS Express in the mid-tier clinical/research segment, particularly in the Asia-Pacific region.

Broad incumbents

• GraphPad Prism: GraphPad Prism is a statistical analysis and graphing tool, also a Dotmatics subsidiary. It is integrated with FCS Express for downstream statistical analysis, making it a portfolio-mate and complementary incumbent in scientific software.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• YouTubeyoutube.com/denovosoftware
• Facebookfacebook.com/FCSExpress
• LinkedInlinkedin.com/company/de-novo-software

Compliance1 record

Revenue estimate

Valuation estimate

Number of profiles

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about De Novo Software