Lectenz Bio

What Lectenz Bio does

Lectenz Bio is a privately-held glycobiology tools company that engineers, manufactures, and sells recombinant glycan-binding reagents, processing enzymes, neoglycoprotein standards, and a bead-based glycan profiling kit to academic researchers, biopharmaceutical manufacturers, and clinical diagnostics developers. The company operates two proprietary technology platforms: the Lectenz® platform produces engineered, enzyme-derived, lectin-like binding proteins with pre-defined glycan specificities generated through computationally-guided directed evolution, while the GlycoSense™ platform uses 6 μm fluorescent microspheres conjugated to these reagents and analyzed on a basic two-color flow cytometer to deliver multiplex glycan profiling in 1–2 hours without mass spectrometry.

The product portfolio includes the SiaFind™ line (Pan-Specific, α2,3-, and α2,6-specific sialic acid detection reagents), N-GlyFind™ and N-GlyRich™ N-glycan core reagents and resins, SiaRich™ affinity columns, recombinant processing enzymes (PNGase F, PNGase F-II, α2,3 Sialidase, Pan Sialidase, O-GlcNAcase, Endo S, Fucosidase, galactosidases, mannosidases), BSA-based neoglycoprotein standards (G0N-, G2N-, G2S2-BSA variants), and supporting buffers. The portfolio is anchored by multiple issued US patents (9,926,612; 10,358,637; 11,434,479; 9,605,014) and corresponding foreign filings, co-assigned with the University of Georgia Research Foundation.

Lectenz Bio sells direct through its e-commerce site (lectenz.com) accepting credit cards, purchase orders, ACH, and wire transfers at unit prices ranging from $25 for buffers to $1,600 for high-value kits, and supplements this with an international distributor network spanning Canada, China, France, the DACH region, India, Japan, Spain/Portugal, Taiwan, and the UK. The company has explicitly pursued non-dilutive funding through NIH SBIR, I-Corps, and commercialization accelerator programs rather than venture capital, and currently employs 1–10 people across its Athens, GA headquarters and San Diego R&D site.

Name

Lectenz Bio

Legal name

Lectenz Bio, Inc.

Website

https://lectenz.com

Company type

Private

Founded year

2009

Operating status

Operating

Headcount range

1–10 employees

Short description

Lectenz Bio is a private biotechnology company that develops and sells proprietary engineered glycan-binding reagents, processing enzymes, and a flow-cytometry-based glycan profiling kit for academic research, biopharmaceutical manufacturing QC, and clinical diagnostics developers worldwide.

Ownership category

akta.pro rank

Product category

Biotechnology Research Reagents

NAICS

Research and Development in Biotechnology (except Nanobiotechnology) (541714), Scientific Research and Development Services (5417)

SIC

In Vitro & In Vivo Diagnostic Substances (2835), Biological Products, (No Disgnostic Substances) (2836)

akta.pro primary industry

Protein Engineering & Directed Evolution Platforms (enzyme/therapeutic protein optimization) (HLAAAIAC)

akta.pro secondary industries

Proteomics & Biomarker Analytical Testing (HLAGADAG), Specialty & Biomarker Laboratory Services (Immunoassays/Flow/Cytometry) (HLAGAEAB)

Keywords

• Glycan detection reagents
• Glycan profiling kits
• Recombinant glycan enzymes
• Neoglycoprotein standards
• Glycobiology research tools

Headquarters

HQ city

Athens

HQ country

United States

HQ region

North America

Offices3 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Technology or R&D, Personnel, Operations, Marketing or Sales, Supply Chain, Infrastructure

Revenue model

1. Product Sales (Research Reagents): Lectenz Bio generates revenue primarily through direct sales of glycan detection kits, glycan processing enzymes, glycan profiling kits, neoglycoproteins, and buffers/accessories. Products are sold via e-commerce, with pricing ranging from $25 to $1,600 depending on product type. The company accepts credit cards, purchase orders, ACH transfers, and wire transfers.

Pricing tiers

Go-to-market motion2 records

Distribution channels2 records

Marketing channels6 records

Core offering

Lectenz Bio develops, manufactures, and sells proprietary glycan detection reagents, glycan processing enzymes, multiplex glycan profiling kits, and neoglycoprotein standards built around two patented technology platforms: the Lectenz® platform (engineered, enzyme-derived lectin-like binding reagents produced via computationally-guided directed evolution) and the GlycoSense™ platform (bead-based flow cytometry assay for near real-time glycan profiling). The company also offers outsourced glycan detection and profiling services using its proprietary tools.

Product overview

Lectenz Bio offers a comprehensive glycobiology product portfolio organized around two core technology platforms: the Lectenz® Platform for engineered, enzyme-derived glycan-binding reagents and the GlycoSense™ Platform for multiplex bead-based glycan profiling. The product line includes: (1) Glycan Detection products under the SiaFind™ brand (Pan-Specific, α2,3-Specific, and α2,6-Specific reagents) for sialic acid detection, and N-GlyFind™ and N-GlyRich™ products for N-glycan core detection and enrichment; (2) Glycan Profiling products including the GlycoSense™ Array Kit for flow cytometry-based glycan analysis; (3) Glycan Processing Enzymes including PNGase F, PNGase F-II, α2,3 Sialidase, Pan Sialidase, O-GlcNAcase, Endo S, Fucosidase, and various galactosidases/mannosidases; (4) Neoglycoprotein Standards (G0N-BSA, G2N-BSA, G2S2 variants) with uniform N-glycan decoration; (5) Buffers and Accessories including binding buffers, reaction buffers, and assay reagents; (6) Glycan Detection and Profiling Services for outsourced analysis. All products are designed to make glycoscience accessible to non-specialist researchers with validated protocols and consistent quality.

Differentiator

Problem solved

Functional benefit

Brands

• Lectenz®: Patented platform technology for engineered lectin-like, enzyme-derived glycan-targeting affinity reagents with high specificity and affinity for glycan biomarkers.
• GlycoSense™
• SiaFind™
• N-GlyFind™
• N-GlyRich™
• SiaRich™

Products and services

• SiaFind™ Pan-Specific Lectenz® Kit Recombinant sialic acid affinity reagent for detection, separation, or enrichment of sialoglycans terminating in Siaα2,3Gal, Siaα2,6Gal, and Siaα2,8Sia in a linkage-independent manner. Available in native, biotinylated, and SureLight® 488 fluorescent formats. Used by research scientists studying sialic acid biology.
• SiaFind™ α2,3-Specific Lectenz® Kit Sialic acid affinity reagent for detection of sialoglycans terminating in Neu5Acα2,3Gal, with high affinity and specificity for α2,3-linked sialic acids. Available in native, biotinylated, and SureLight® 488 formats. Used in ELISA, Western blot, and immunohistochemistry workflows.
• SiaFind™ α2,6-Specific Reagent Kit Recombinant protein engineered from Polyporus squamosus lectin (PSL) for sensitive, robust detection of Siaα2,6Gal. For use in ELISA, Western blot, and immunohistochemistry. Not recommended for flow cytometry.
• SiaFind™ Linkage Profiling Kit Kit for profiling sialic acid linkages, enabling comparison of α2,3 versus α2,6 sialic acid linkages between samples.
• N-GlyFind™ Core-Specific Reagent Kit Recombinant protein engineered from Mus musculus Fbs1 (Fbxo2) for detection of ManGlcNAc2-Asn within N-glycan core structure. Applications include ELISA, Western blot, and other assays. Also available as GST fusion variant with 10X sensitivity.
• N-GlyRich™ Core-Specific Resin Kit Agarose resin coupled with N-GlyFind™ Core-Specific Reagent for enrichment and purification of N-glycoconjugates. Features low volume (≤500 μL), benchtop use, reusability, and stability at 4°C for months.
• SiaRich™ α2,3-Specific Affinity Column Affinity column for enriching glycoproteins containing α2,3-linked sialic acid. Used for streamlined glycoprotein analysis and biomarker discovery.
• GlycoSense™ Array Kit Multiplex bead-based kit using flow cytometry to detect key terminal glycan monosaccharides (sialic acid, galactose, GlcNAc) on N-linked glycans. Generates high-level glycan analysis results in 1-2 hours using a basic two-color flow cytometer.
• PNGase F Recombinant enzyme for cleaving N-linked glycans without core α1,3 fucose. Available in 4,000 or 20,000 unit formats. pH range 6.0-9.0.
• PNGase F-II Recombinant enzyme that cleaves N-linked glycans with or without core fucose, including α1,3-core fucosylated glycans from insect or plant proteins. 100 units. pH range 5.5-8.0.
• α2,3 Sialidase Recombinant enzyme that cleaves terminal α2,3-linked sialic acid. 5,000 units. pH range 4.0-8.0.
• Pan Sialidase Recombinant neuraminidase (exo-α-sialidase, GH33) cloned from Arthrobacter ureafaciens. Catalyzes hydrolysis of terminal α-linked N-acetylneuraminic acid (Neu5Ac). 5,000 units.
• O-GlcNAcase Recombinant enzyme that cleaves O-linked β-N-Acetylglucosamine (GlcNAc). 1,000 units. pH range 6.0-9.0.
• FasTEV™ Protease TEV protease with enhanced stability and catalytic activity. Cleaves the peptide bond between glutamine and glycine or serine of consensus sequence ENLYFQ↑G/S. Used to remove His-tags from Lectenz reagents. 1,000 units.
• Thermophilic Fucosidase Enzyme that cleaves α1,2/3/4/6-linked fucose at high temperature. 5,000 units. pH range 3.5-8.0.
• Endo S Recombinant enzyme that cleaves N-linked glycans from IgG heavy chain. 2,500 units. pH range 5.5-6.5.
• β1,3 Galactosidase Recombinant enzyme that cleaves terminal β1,3-linked galactose. 2,000 units. pH range 4.5-7.5.
• α1,3 Mannosidase Recombinant enzyme that cleaves terminal α1,3-linked mannose. 1,000 units. pH range 5-8.5.
• β-N-Acetylhexosaminidase Recombinant enzyme (GH20) that catalyzes hydrolysis of non-reducing terminal GlcNAc and GalNAc. 500 units. pH range 3.5-7.5.
• β-N-Acetylglucosaminidase Recombinant enzyme (GH20) cloned from Streptococcus pneumoniae that catalyzes hydrolysis of non-reducing terminal N-Acetylglucosamine (GlcNAc). 500 units.
• G0N-BSA Neoglycoprotein BSA decorated uniformly with G0N (Man3GlcNAc2) N-glycan structure. Ideal N-glycoprotein standard for ELISA, Western blots, flow cytometry, and other applications.
• G2N-BSA Neoglycoprotein BSA decorated uniformly with G2N (biantennary N-glycan) structure. Ideal N-glycoprotein standard for glycan-binding reagent validation.
• G2S2(α2,3)N-BSA Neoglycoprotein BSA decorated uniformly with G2S2(α2,3) N-glycan structure containing α2,3-linked sialic acid. Ideal for validating α2,3-specific reagents.
• G2S2(α2,6)N-BSA Neoglycoprotein BSA decorated uniformly with G2S2(α2,6) N-glycan structure containing α2,6-linked sialic acid. Ideal for validating α2,6-specific reagents.
• Glycan Detection and Profiling Services Outsourced glycan analysis services using Lectenz Bio's proprietary methods. Includes SiaFind characterization (Western blot, IHC, ELISA, flow cytometry, biolayer interferometry), SiaRich chromatography, and GlycoSense GlycoPrint analysis for research and industry customers requiring timely and cost-effective outsourced solutions.

Quantifiable outcome

• GlycoSense™ generates high-level glycan analysis in 1-2 hours including incubation time
• +2 more outcomes

Segments3 records

Ideal customer profiles3 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Integration1 record

Feature5 records

Partnerships

Seven partnerships are on record, tiered minor, core and historical.

• Society for GlycobiologyminorOthers · 25 June 2026Lectenz Bio sponsored and presented posters at GGS 2026 (Glycobiology conference). Principal Scientist Sylvain Lehoux gave talks on Neoglycoprotein technology. Also sponsored Society for Glycobiology 2025 in San Diego and 2024 in Amelia Island, Florida.
• Abyntek BiopharmacoreChannel Partner/ Reseller/ Distributor · 8 June 2026Distribution agreement signed June 8, 2026. Abyntek Biopharma, a leading Spanish life sciences distributor, will promote and supply Lectenz Bio products to researchers across Spain and Portugal. This partnership expands Lectenz Bio's European market presence.
• SialoGlyco ConferenceminorOthers · 28 May 2026Lectenz Bio attended SialoGlyco 2026 in Taipei. CEO and CSO Lori Yang presented on SiaFind and N-GlyFind reagents. Also sponsored SialoGlyco 2024 in Lille, France.
• AmyJet Scientific Inc.coreChannel Partner/ Reseller/ Distributor · 8 March 2024Distribution agreement signed March 8, 2024. AmyJet Scientific Inc., a Chinese life science distributor, will distribute Lectenz Bio products in China. Located at 13/F, Block 1, Harbour of Technology Times, No.35 Optical Valley Ave, Wuhan, Hubei 430074, China.
• Johnson & Johnson Innovation, JLABShistoricalStrategic or Co-development PartnerLectenz Bio (formerly Glycosensors and Diagnostics) established satellite operations in 2013 as a resident company of Johnson & Johnson Innovation, JLABS San Diego. Graduated from JLABS in 2016 and relocated to San Diego Science Center. Historical partnership that facilitated early company development.
• University of Georgia (Complex Carbohydrate Research Center)coreStrategic or Co-development PartnerLectenz Bio was spun-out from Prof. Robert J. Woods' research group at UGA's Complex Carbohydrate Research Center in 2009. Company maintains close ties with university researchers including Scientific Advisory Board members Prof. Robert Woods, Prof. Gerald Hart, and Prof. Michael Pierce. Co-founder Prof. Woods holds joint faculty appointments at UGA.
• University of Copenhagen Centre for GlycomicsminorStrategic or Co-development PartnerCollaborating academic institution. Dr. Hans Wandall and Mikkel Andersen from University of Copenhagen provided immunofluorescence images using Lectenz products on human skin cells as part of product validation.

Scale indicators4 records

Recent moves10 records

Expansion highlights5 records

Direct peers

• Vector Laboratories (Maravai LifeSciences): Vector Laboratories (now part of Maravai LifeSciences) is the traditional leader in lectin-based glycan detection reagents. It is the most direct competitor to Lectenz Bio's SiaFind™ and N-GlyFind™ products, and both companies serve the same academic and biopharma glycobiology customer base.
• New England Biolabs: NEB is the dominant supplier of PNGase F and other glycan-processing enzymes (including the PNGase F-II equivalent Lectenz sells). The two companies directly compete in recombinant glycoenzyme reagent sales to the same academic and biopharma customers.
• Promega Corporation: Promega sells glycoprotein analysis reagents and detection kits for life science research, directly overlapping with Lectenz Bio's glycan detection product portfolio. Both companies target bench scientists needing validated, easy-to-use reagent workflows.
• Galab Laboratories: Galab Laboratories is a contract research organization specializing in glycan analysis services. It competes with Lectenz Bio's outsourced glycan detection and profiling service line, addressing the same biopharma and food industry customers needing glycan characterization.

Broad incumbents

• Millipore Sigma (Merck KGaA Life Science): Millipore Sigma offers the broadest catalog of lectins, glycan reagents, and analytical enzymes globally. As a broad incumbent, it competes with Lectenz Bio across nearly every product category but does not specialize in the engineered Lectenz® reagent niche.
• Bio-Techne (R&D Systems): Bio-Techne sells antibodies, proteins, and lectin reagents through R&D Systems, Novus Biologicals, and Tocris brands. The catalog overlaps with Lectenz Bio's glycan detection reagent offerings, but Bio-Techne operates as a broad protein reagent provider rather than a glycobiology specialist.
• Thermo Fisher Scientific: Thermo Fisher is the largest life sciences tools company and offers glycan analysis reagents, lectins, and analytical instruments. It competes with Lectenz Bio primarily through its broad catalog and established biopharma customer relationships rather than technical specialization in engineered glycan binders.
• Bruker Corporation: Bruker is the leading mass spectrometry-based glycan analysis platform provider. Its instruments represent the incumbent workflow that Lectenz Bio's GlycoSense™ platform positions against — both serve biopharma glycosylation characterization needs but through different technical approaches.
• Agilent Technologies: Agilent provides glycan analysis reagents, columns, and mass spectrometry-based workflows used by biopharma manufacturers for glycosylation QC. It overlaps with Lectenz Bio in serving biopharma customers analyzing glycosylation but via established analytical workflows rather than Lectenz's flow cytometry-based approach.

Emerging players

• Creative Biolabs: Creative Biolabs offers glycan-related products and custom services including glyco-engineering and glycan analysis. As an emerging player it overlaps with Lectenz Bio in target customer base but is a custom services provider rather than a focused reagent product company.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/lectenz_bio
• LinkedInlinkedin.com/company/lectenz_bio

Revenue estimate

Valuation estimate

Number of profiles

Profiles1 record

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Lectenz Bio