What TissueGnostics GmbH does

TissueGnostics GmbH is a Vienna-based precision-medicine and digital-pathology vendor founded in 2003 that builds modular whole-slide imaging systems and AI-assisted image-analysis software used by academic, pharmaceutical, and clinical-research laboratories. The company's product stack centers on the TissueFAXS platform — a modular, automated microscope family covering brightfield, fluorescence, spinning-disk confocal, and multispectral (CHROMA, SPECTRA) imaging, available from entry-level scanners (StrataFAXS II, COLUBRIS) up to high-throughput batch units (TissueFAXS 200) — and on the StrataQuest analysis software, which provides spatial immunophenotyping, tissue classification, deep-learning nuclei segmentation, and machine-learning tissue classifiers.

The business model combines capital-equipment sales (TissueFAXS hardware) with recurring software licences/subscriptions (TissueFAXS Suite, TissueQUEST, HistoQUEST, StrataQuest), service and support contracts, and professional services for training and workflow optimisation. Distribution is hybrid: wholly-owned regional entities in Austria (HQ), Germany coverage through the European office, Australia, China, South Africa, Romania, the UK, and a LATAM division established in 2025 are complemented by a global distributor network (Klein Scientific, Biogenuix, Incise Infotech, Ursulab, ScientiaLux, etc.) reaching 30 countries across six continents. Pricing is quote-based and not publicly disclosed; the company targets enterprise academic and biopharma buyers.

Customer segments are horizontal, with academic research institutions (oncology, immunology, dermatology, neuroscience) as the primary buyer, supplemented by pharmaceutical/biotech drug-discovery groups, core imaging facilities, and clinical research organisations. Adoption is evidenced by more than 3,000 peer-reviewed customer publications and named long-tenure users including Medical University of Vienna, RWTH Aachen, Northwestern University, University of Cape Town and the Pan African Cancer Research Institute. The company operates an active AI/research collaboration footprint across multiple EU-funded Marie Skłodowska-Curie training networks and Horizon Europe consortia, positioning its platform as a bridge between research microscopy and spatial-biology workflows.

Name

TissueGnostics GmbH

Legal name

TissueGnostics GmbH

Website

https://tissuegnostics.com

Company type

Private

Founded year

2003

Operating status

Operating

Headcount range

11–50 employees

Short description

TissueGnostics GmbH develops modular whole-slide imaging systems (TissueFAXS) and AI-assisted image-analysis software (StrataQuest) for digital pathology, serving academic, pharmaceutical, and clinical-research laboratories across more than 30 countries.

Ownership category

akta.pro rank

Product category

Digital Pathology Imaging Systems

NAICS

Research and Development in Biotechnology (except Nanobiotechnology) (541714), Diagnostic Imaging Centers (621512)

SIC

Laboratory Analytical Instruments (3826), Surgical & Medical Instruments & Apparatus (3841)

akta.pro primary industry

Anatomic Pathology & Histology/Cytology IVD (Tissue Diagnostics) (HLAHAAAE)

akta.pro secondary industries

Microscopy, Imaging & Flow Cytometry Instruments (HLAGAIAE), Medical Imaging AI (HDAAAEAH), Cytology & Histopathology Diagnostics (IHC, ISH, tissue-based assays) (HLAAALAI)

Keywords

• Digital pathology
• Tissue imaging systems
• Whole-slide imaging
• Spatial tissue cytometry
• Image analysis software

Headquarters

HQ city

Vienna

HQ country

Austria

HQ region

Europe

Offices6 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Technology or R&D, Personnel, Supply Chain, Marketing or Sales, Operations

Revenue model

1. Hardware Systems Sales: Sale of TissueFAXS imaging platforms including TissueFAXS Plus, TissueFAXS FLUO, TissueFAXS HISTO, TissueFAXS 200, TissueFAXS SL, and TissueFAXS SPECTRA systems
2. Software Licenses and Subscriptions: Software modules including TissueFAXS, TissueQUEST, HistoQuest, and StrataQuest offered as perpetual licenses or subscription models with different configurations for fluorescence and brightfield analysis
3. Professional Services and Training: Training services for product operation, pipeline optimization, and customization support provided to customers
4. Service and Support Contracts: Ongoing technical support and maintenance services for imaging systems and software

Pricing tiers

Go-to-market motion3 records

Distribution channels3 records

Marketing channels8 records

Core offering

TissueGnostics GmbH designs, manufactures, and sells modular whole-slide microscopy imaging platforms (the TissueFAXS family) and accompanying AI-driven image analysis software (StrataQuest) for biomedical and clinical research. Its solutions enable automated brightfield, fluorescence, multispectral, and confocal imaging of tissue sections, combined with quantitative, contextual image analysis for applications such as cancer research, immunology, biomarker discovery, and spatial tissue cytometry.

Product overview

TissueGnostics provides a modular, platform-based product architecture centered on the TissueFAXS imaging platform and StrataQuest analysis software. The core TissueFAXS Platform serves as the modular imaging system supporting multiple configurations (CHROMA for multispectral, SPECTRA for spectral unmixing, Q for confocal, SL/200 for high-throughput batch scanning, and TissueFAXSplus as a comprehensive cell analysis system). StrataQuest software provides the analytical layer with AI-enhanced capabilities including deep learning nuclei segmentation and machine learning tissue classification, supported by a library of predefined App Center workflows. Legacy products (TissueQuest, HistoQuest) and entry-level solutions (StrataFAXS II, COLUBRIS) round out the portfolio. The company positions itself at the intersection of whole-slide imaging and spatial biology, with over 20 years of innovation since the 2006 launch of the world's first tissue cytometer.

Differentiator

Problem solved

Functional benefit

Brands

• TissueFAXS: Modular imaging platform for whole-slide imaging and scanning of diverse sample types
• StrataQuest
• COLUBRIS
• TissueQuest
• HistoQuest
• App Center
• TissueFAXS Spectra
• TissueFAXS CHROMA

Products and services

• TissueFAXS Platform Modular whole-slide imaging platform for scanning diverse sample types including brightfield, fluorescence, spinning-disk confocal, and multispectral imaging, used by academic and pharmaceutical researchers for automated high-throughput tissue imaging.
• TissueFAXS CHROMA

Quantifiable outcome

• 225% revenue increase vs pre-pandemic levels (2023)
• +3 more outcomes

Named customers7 records

Segments4 records

Ideal customer profiles4 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

AI capability7 records

Feature8 records

Partnerships

22 partnerships are on record, tiered core, flagship and minor.

• Klein ScientificcoreChannel Partner/ Reseller/ Distributor · 18 February 2026Business partnership to bring advanced microscopy solutions to researchers and institutions across Australia. Expands TissueGnostics reach in Asia-Pacific and gives Klein Scientific customers access to tissue cytometry and spatial phenotyping tools.
• Software Competence Centre Hagenberg (SCCH)coreStrategic or Co-development PartnerIndustry partnership for The Virtual Histopathologist for Precision Cancer Diagnostics project (2022-2025), developing AI-based decision support system for histopathology with deep learning algorithms within transfer learning framework. Funded by Austrian Chamber of Commerce Life Science Call 2021.
• SCOPE Microscopy Facility, UMass Chan Medical SchoolflagshipStrategic or Co-development PartnerCenter of Excellence recognized for its role as core imaging facility supporting a large and diverse research community. Led by Dr. Christina Baer, SCOPE provides slide scanning and image analysis services enabling wide range of research applications with high-throughput workflows.
• eRaDicate (Horizon-Europe Marie Sklodowska-Curie Doctoral Network)coreStrategic or Co-development PartnerInternational PhD programme in cancer field. PhD candidates test novel drugs as anti-cancer agents using molecular biology, biochemical methods, and bioinformatics approaches. TissueGnostics hosts kick-off meeting and provides technology for drug testing.
• COMET-Zentrum VASCagecoreStrategic or Co-development PartnerResearch Center on Vascular Aging and Stroke in Innsbruck. Focuses on stroke and age-related blood vessel changes. Part of COMET center developing innovative strategies for diagnosis, therapy and rehabilitation with world-leading experts from universities, clinics and companies.
• STOP SPREAD BAD BUGS (SSBB) ProjectcoreStrategic or Co-development PartnerMarie Sklodowska-Curie Actions research training consortium training 15 early stage researchers in drug development, infectiology, immunology and pharmacology. TissueGnostics hosts 3 Doctoral Candidates and provides equipment, service and training.
• ARC Training Centre for Cell and Tissue Engineering TechnologiesminorStrategic or Co-development PartnerNewly funded centre jointly led by Monash University in collaboration with Queensland University of Technology with 22 partner organisations. TissueGnostics participates as industry partner.
• African Microscopy Initiative (AMI) Imaging CentrecoreStrategic or Co-development PartnerTissueGnostics is founding sponsor at AMI Imaging Centre at University of Cape Town, funded by Chan Zuckerberg Initiative and Melinda and Bill Gates Foundation. Centre offers TissueFAXS SL slide scanner for scientists working in Africa.
• Euro-BioImaging Industry Board (EBIB)minorStrategic or Co-development PartnerTissueGnostics is member of EBIB. Cooperates with other members to meet research needs in microscopy, molecular imaging, image analysis and tissue cytometry. Offers webinars, training opportunities, equipment support and knowledge exchange.
• Brazilian Society of Microscopy and Microanalysis (SBMM)minorStrategic or Co-development PartnerTissueGnostics is associated company of SBMM, the oldest society of microscopy in Latin America. SBMM is key player in progress of microscopy and microanalysis research in Brazil and South America.
• COMULIS (COST Action)coreStrategic or Co-development PartnerCorrelated Multimodal Imaging in Life Sciences COST Action. TG was among first members. Awarded additional funding from COST via COST Innovators Grant (CIG 17121) MultEMPlex and Chan-Zuckerberg-Initiative grant for COMULISglobe expansion.
• K1 Excellence Centre microONEcoreStrategic or Co-development PartnerResearch project on relationship between micro-/nanoplastic particles and cancer. Community of researchers and industry partners work together to provide evidence on how different particles influence tumor development and spread using colorectal cancer as example.
• Queensland University of Technology (QUT)coreStrategic or Co-development PartnerREDI Industry Fellowship Program collaboration. Associate Professor Jyotsna Batra develops antibodies detecting prostate cancer with TissueGnostics in Vienna.
• AIDPATH Partners (Marie Curie FP7)coreStrategic or Co-development PartnerAcademia and Industry Collaboration for Digital Pathology - EU FP7 funded project. Partners include Astra Zeneca, Leica Biosystems, Barco, universities including Nottingham, UCLM, Udine, and others.
• ALKATRAS Partners (Marie Curie FP7)coreStrategic or Co-development PartnerEuropean Research Initiative on ALK-related malignancies. 15 recruited fellows incorporated into international academic study groups with secondments including TissueGnostics. Partners include Charité Berlin, Roche, Novartis, Pfizer, and 14 other institutions.
• CaSR Biomedicine Partners (Horizon 2020)coreStrategic or Co-development PartnerInternational research project investigating calcium-sensing receptor for treatment of cancer, diabetes, and cardiovascular diseases. Partners include Medical University of Vienna (coordinator), Amgen, Novartis, Cardiff University, Oxford, Manchester and 12 others.
• HELICAL Partners (Horizon 2020)coreStrategic or Co-development PartnerHealthcare Data Linkage for Clinical Benefit training network with 17 academic and 9 industry partners. TissueGnostics is industry partner in training early stage researchers in big data analysis using autoimmune vasculitis as paradigm.
• InCeM Partners (Horizon 2020)coreStrategic or Co-development PartnerResearch Training Network on Integrated Component Cycling in Epithelial Cell Motility. Focus on cell migration research. 11 beneficiaries from 6 European countries and Israel including 4 universities, 4 research institutes, and 3 companies.
• Department of General, Visceral and Transplant Surgery, RWTH Aachen University HospitalflagshipStrategic or Co-development PartnerCenter of Excellence recognized for strong and long-standing collaboration. Led by Prof. Klinge and Dr. Dievernich with significant scientific contributions through numerous high-impact publications using TissueGnostics technologies.
• Institute for Pathophysiology and Allergy Research, Medical University of ViennaflagshipStrategic or Co-development PartnerCenter of Excellence recognized for long-standing collaboration and outstanding scientific contributions. Producing numerous high-impact publications using TissueGnostics technologies with active involvement in collaborative research projects.
• Department for Immunology, Leibniz Institute for Immunotherapy (LIT)flagshipStrategic or Co-development PartnerCenter of Excellence recognized for long-standing collaboration since 2012. Led by Prof. Uwe Ritter with significant scientific contributions through publications and active participation in joint webinars and conference activities.
• Institute of Chemistry, University of São PauloflagshipStrategic or Co-development PartnerCenter of Excellence recognized for long-standing collaboration and scientific impact. First in South America to implement TissueFAXS systems. Prof. Henning Ulrich is key collaborator and scientific advisor to TissueGnostics.

Scale indicators7 records

Recent moves6 records

Expansion highlights6 records

Direct peers

• Akoya Biosciences: Akoya's Phenoptics platform enables multiplexed spatial tissue analysis and is one of the closest direct competitors to TissueGnostics' StrataQuest/TissueFAXS workflow, particularly in immuno-oncology and tumor microenvironment research.
• Hamamatsu Photonics: Hamamatsu's NanoZoomer digital pathology slide scanners compete head-to-head with TissueFAXS for whole-slide brightfield and fluorescence imaging in research and clinical labs globally.
• 3DHistech: 3DHistech sells P1000/MIRAX whole-slide scanners and CaseViewer/QuantCenter software, directly overlapping with TissueFAXS and StrataQuest in digital pathology research workflows.
• Visiopharm: Visiopharm's Phenomap and AI-based image analysis software competes with StrataQuest for quantitative pathology and tissue classification workloads in research and pharma.
• Indica Labs: Indica Labs' HALO and HALO AI platforms offer quantitative tissue image analysis comparable to StrataQuest, used widely in pharma and academic spatial pathology.

Broad incumbents

• Leica Biosystems: Leica's Aperio line of whole-slide scanners and BrightVision/ImageScope software is the dominant pathology imaging platform in clinical labs, offering overlapping but broader capabilities than TissueGnostics' research-focused portfolio.
• Roche Diagnostics (Ventana): Roche's Ventana digital pathology platform integrates scanners, image analysis, and a vast reagent business, making Roche a much larger incumbent that competes for the same translational/clinical pathology budgets TissueGnostics targets.
• Philips Digital Pathology: Philips IntelliSite Pathology Solution combines whole-slide scanners and image management software, representing a broad-incumbent alternative to TissueGnostics in both research and clinical digital pathology.

Emerging players

• PathAI: PathAI applies deep learning to pathology images, with AISight and pharma services overlapping with StrataQuest's AI/ML classification features but focused on clinical-grade decision support and biomarker development.
• Aignostics: Aignostics is an AI-pathology spinout from Charité Berlin building computational pathology products for pharma and diagnostics, competing with StrataQuest's AI tissue classification capabilities in translational research.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat6 records

Key risks6 records

Key highlights7 records

Customer concentration

• Xx.com/TissueGnostics
• Facebookfacebook.com/TissueGnosticsGlobal
• LinkedInlinkedin.com/company/tissuegnostics
• Instagraminstagram.com/tissuegnostics

Revenue estimate

Valuation estimate

Number of profiles

Profiles4 records

Subsidiaries8 records

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about TissueGnostics GmbH