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MRC Laboratory of Molecular Biology

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uuid000dxw3

Namestring
MRC Laboratory of Molecular Biology
Legal namestring
MRC Laboratory of Molecular Biology
Company typeenum
Private
Founded yearint
1947
Operating statusenum
Operating
Ownership categoryenum
Headcount rangeband
5,001–10,000
akta.pro rankint
HeadquartersCambridge, United Kingdom
HQ citystring
Cambridge
HQ countrystring
United Kingdom
HQ regionstring
Europe
Markets served

Serves global market

Offices1 record

Each record includes

City, Country, Type, Description, Source

Keyword5 values
molecular biology research, structural biology, cryo-electron microscopy, protein design methods, biomedical research
NAICS code3 codes
  • 54171
  • 541714
  • 5417
SIC code1 code
  • 8731
Product category
Biomedical Research Services
GTM motion1 record

Each record includes

Type, Description, Source

Revenue model2 records
1Core Government Funding
TypeSubscription Recurring
Description

The LMB receives generous core-funding from the Medical Research Council (MRC), which is part of UK Research and Innovation (UKRI). This provides stable base funding for fundamental research operations.

mrclmb.ac.uk
2Commercialization and Licensing
TypeLicensing Royalties
Description

Discoveries from LMB research have led to highly successful commercialisations. The Achievements page specifically mentions 'Commercial Activities' as a section, indicating active commercialization of research outputs through licensing, patents, and spin-out companies.

mrclmb.ac.uk
Marketing channels6 records

Each record includes

Title, Type, Stage, Description, Source

Distribution channels4 records

Each record includes

Title, Type, Scope, Target buyer, Description, Source

Cost components5 values
Personnel, Technology or R&D, Infrastructure, Operations, Others
GTM typeB2B
B2B
Offering typeServices
Services
Core offering1 text field

The MRC Laboratory of Molecular Biology (LMB) is a publicly funded fundamental research institute dedicated to understanding biological processes at atomic, molecular, cellular, and organismal levels. It pursues ambitious research across over 50 scientific groups using cutting-edge facilities such as cryo-electron microscopy, computational protein design, and brain connectomics. Outputs are disseminated to the global scientific community through open-access publications, open-source scientific software, training seminars, and technology commercialisation through licensing and spin-out companies.

Differentiator
Functional benefit
Problem solved
Quantifiable outcome1 of 2 values shown
  • Discoveries have led to highly successful commercialisations and medical advances that have improved human life
+1 more record
Product overview1 text field

The MRC Laboratory of Molecular Biology (LMB) is a fundamental research institute dedicated to understanding biological processes at atomic, molecular, cellular, and organismal levels. The LMB comprises over 50 scientific groups pursuing research across multiple divisions, supported by cutting-edge scientific facilities including cryo-EM, electron microscopy, and other advanced imaging technologies. As a research institution rather than a commercial product company, LMB's offerings include published scientific research, training seminars, and the LMB Developed Software collection of research tools.

Product and service1 record
1LMB Developed Software
CategoryScientific Software Tools
Description

A collection of open-source scientific software tools developed by LMB researchers and shared with the global scientific research community, including tools such as SpineDL and SAMJ (Segment Anything Model for ImageJ/Fiji). The tools are made freely available for use in biological and biomedical research workflows.

Scale indicator4 records

Each record includes

Type, Value, Description, Source

Partnership6 partners
Strategic tierMajorTypeStrategic or Co-development Partner
Description

International research collaboration partner in the development of novel designer fluorescent proteins with near-infrared and short-wave infrared spectra capabilities.

Strategic tierMajorTypeStrategic or Co-development Partner
Description

Collaborating institution in the international research team developing novel fluorescent proteins using computational protein design.

Strategic tierMajorTypeStrategic or Co-development Partner
Description

Key collaboration partner in cancer research including the National Center for Tumor Diseases Dresden for developing fluorescent proteins with applications in cancer detection during surgery.

Strategic tierMajorTypeStrategic or Co-development Partner
Description

International consortium focused on whole-brain connectome mapping, involving LMB researchers led by Greg Jefferis.

Strategic tierMajorTypeStrategic or Co-development Partner
Description

Partner institution for the annual LMB-EPFL Graduate Life Sciences Symposium, fostering graduate-level scientific exchange.

6National Center for Tumor Diseases Dresden
Strategic tierMajorTypeStrategic or Co-development Partner
Description

Led by Professor Oliver Bruns, this institution collaborated on developing novel near-infrared fluorescent proteins for biomedical applications including cancer surgery and disease monitoring.

mrclmb.ac.uk
Recent move6 records

Each record includes

Date, Type, Title, Description, Source

Expansion highlight5 records

Each record includes

Type, Description

Peers10 records
TypeDirect peer
Description

Cambridge-based genomics research institute funded by Wellcome; directly comparable in location, scale and a major UK centre for molecular/genomic biology with active technology transfer and spin-out activity.

TypeDirect peer
Description

US non-profit research organization with deep structural biology, chemistry and immunology programmes; directly comparable in fundamental-discovery mission and technology-transfer output.

TypeDirect peer
Description

US genomic medicine and chemical biology institute with overlapping strengths in structural biology, CRISPR/functional genomics, and large-scale data platforms; a global benchmark for academic-to-commercial translation.

TypeDirect peer
Description

California-based basic-research institute working on molecular and cellular biology with a comparable small-group, high-impact-discovery model and a history of technology commercialization.

TypeDirect peer
Description

London-based biomedical discovery institute with comparable scale (~1,500+ scientists), UK government/core-funding model, and broad molecular biology remit; the closest UK peer to LMB in mission, funding profile, and translational pipeline.

TypeDirect peer
Description

US graduate-research university with Nobel-rich tradition of small-lab molecular/cell biology; comparable in scale, talent density and historical commercialization of basic discoveries.

7European Molecular Biology Laboratory (EMBL)
TypeDirect peer
Description

Intergovernmental European molecular biology research organization with structural biology, bioinformatics, and instrumentation programmes directly comparable to LMB's cryo-EM and software work.

TypeDirect peer
Description

HHMI's research campus shares LMB's model of small group-driven, technology-intensive fundamental biology (imaging, connectomics, tool-building) and is a named LMB collaboration partner.

TypeDirect peer
Description

MIT-affiliated biomedical research institute with a similar small-group structure, focus on fundamental molecular/cell biology, and an active spin-out and licensing track record.

TypeDirect peer
Description

German basic-research institute pursuing molecular cell biology with quantitative imaging and model-organism approaches; comparable in scientific scope and core-funding model.

Market position
Strengths5 records

Each record includes

Headline, Details, Source

Weaknesses5 records

Each record includes

Headline, Details, Source

Competitive moat5 records

Each record includes

Type, Details

Key risks5 records

Each record includes

Headline, Details, Source

Key highlights7 records

Each record includes

Headline, Details, Source

Customer concentration

Classification, Details

Segment2 records

Each record includes

Title, Type, Primary, Description, Pain point addressed, Use case, Source

Ideal customer profile2 records

Each record includes

Profile, Firmographic size, Sales motion, Sales cycle length, Buying structure, Purchase trigger, Buyer persona, Geography, Industry vertical, Primary use case, Description, Pain points, Evidence proof points, Target buyer

Technology focused
Yes
API detail
Has APIbool
No

Docs URL, Description

AI maturity
App detail

Has app

Feature4 records

Each record includes

Title, Differentiator, Description, Source

Core technology
Revenue estimate
Valuation estimate
Number of profiles
Profiles3 records

Each record includes

Name, Designation, Designation category, Overview, Profile commentary, Source

No data
No data
Funding overview

Funding stage, Last funding date, Total funding USD

Funding rounds

Each record includes

Round, Amount USD, Date, Pre money valuation, Total investors, Investors, News

Investors

Each record includes

Name, Type, Date of entry, Rounds participated, Website

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Each record includes

Name, Acquisition type, Announced date, Completed date, Status, Website, News

Investment

Each record includes

Name, Round, Announced date, Lead investor, Website, News

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

MRC Laboratory of Molecular Biology

Biomedical Research Serviceswww2.mrc-lmb.cam.ac.uk

MRC Laboratory of Molecular Biology firmographics

Firmographics
Name
MRC Laboratory of Molecular Biology
Legal name
MRC Laboratory of Molecular Biology
Website
https://www2.mrc-lmb.cam.ac.uk
Company type
Private
Founded year
1947
Operating status
Operating
Headcount range
5,001–10,000 employees
Ownership category
akta.pro rank

Where MRC Laboratory of Molecular Biology is headquartered

Location

Headquarters

HQ city
Cambridge
HQ country
United Kingdom
HQ region
Europe

Offices1 record

Markets served

MRC Laboratory of Molecular Biology business model

Business model
GTM type
B2B
Offering type
Services
Cost components
Personnel, Technology or R&D, Infrastructure, Operations, Others

Revenue model

  1. Core Government Funding: The LMB receives generous core-funding from the Medical Research Council (MRC), which is part of UK Research and Innovation (UKRI). This provides stable base funding for fundamental research operations.
  2. Commercialization and Licensing: Discoveries from LMB research have led to highly successful commercialisations. The Achievements page specifically mentions 'Commercial Activities' as a section, indicating active commercialization of research outputs through licensing, patents, and spin-out companies.

Go-to-market motion1 record

Distribution channels4 records

Marketing channels6 records

MRC Laboratory of Molecular Biology product offering

Product offering

Core offering

The MRC Laboratory of Molecular Biology (LMB) is a publicly funded fundamental research institute dedicated to understanding biological processes at atomic, molecular, cellular, and organismal levels. It pursues ambitious research across over 50 scientific groups using cutting-edge facilities such as cryo-electron microscopy, computational protein design, and brain connectomics. Outputs are disseminated to the global scientific community through open-access publications, open-source scientific software, training seminars, and technology commercialisation through licensing and spin-out companies.

Product overview

The MRC Laboratory of Molecular Biology (LMB) is a fundamental research institute dedicated to understanding biological processes at atomic, molecular, cellular, and organismal levels. The LMB comprises over 50 scientific groups pursuing research across multiple divisions, supported by cutting-edge scientific facilities including cryo-EM, electron microscopy, and other advanced imaging technologies. As a research institution rather than a commercial product company, LMB's offerings include published scientific research, training seminars, and the LMB Developed Software collection of research tools.

Differentiator

Problem solved

Functional benefit

Products and services

  • LMB Developed Software A collection of open-source scientific software tools developed by LMB researchers and shared with the global scientific research community, including tools such as SpineDL and SAMJ (Segment Anything Model for ImageJ/Fiji). The tools are made freely available for use in biological and biomedical research workflows.

Quantifiable outcome

  • Discoveries have led to highly successful commercialisations and medical advances that have improved human life
  • +1 more outcomes

Companies that use MRC Laboratory of Molecular Biology

Customer profile

Segments2 records

Ideal customer profiles2 records

MRC Laboratory of Molecular Biology technology and API

Technology

Technology focussed Yes

API detail

Has API
No
API docs
API detail

Core technology

AI maturity

App detail

Feature4 records

MRC Laboratory of Molecular Biology partnerships and signals

Strategic signal

Partnerships

Six partnerships are on record, tiered major.

  • University of WashingtonmajorStrategic or Co-development PartnerInternational research collaboration partner in the development of novel designer fluorescent proteins with near-infrared and short-wave infrared spectra capabilities.
  • Howard Hughes Medical InstitutemajorStrategic or Co-development PartnerCollaborating institution in the international research team developing novel fluorescent proteins using computational protein design.
  • German Cancer Research Center (DKFZ)majorStrategic or Co-development PartnerKey collaboration partner in cancer research including the National Center for Tumor Diseases Dresden for developing fluorescent proteins with applications in cancer detection during surgery.
  • FlyWire ConsortiummajorStrategic or Co-development PartnerInternational consortium focused on whole-brain connectome mapping, involving LMB researchers led by Greg Jefferis.
  • École Polytechnique Fédérale de Lausanne (EPFL)majorStrategic or Co-development PartnerPartner institution for the annual LMB-EPFL Graduate Life Sciences Symposium, fostering graduate-level scientific exchange.
  • National Center for Tumor Diseases DresdenmajorStrategic or Co-development PartnerLed by Professor Oliver Bruns, this institution collaborated on developing novel near-infrared fluorescent proteins for biomedical applications including cancer surgery and disease monitoring.

Scale indicators4 records

Recent moves6 records

Expansion highlights5 records

MRC Laboratory of Molecular Biology competitors and assessment

Company assessment

Direct peers

  • Wellcome Sanger Institute: Cambridge-based genomics research institute funded by Wellcome; directly comparable in location, scale and a major UK centre for molecular/genomic biology with active technology transfer and spin-out activity.
  • Scripps Research: US non-profit research organization with deep structural biology, chemistry and immunology programmes; directly comparable in fundamental-discovery mission and technology-transfer output.
  • Broad Institute of MIT and Harvard: US genomic medicine and chemical biology institute with overlapping strengths in structural biology, CRISPR/functional genomics, and large-scale data platforms; a global benchmark for academic-to-commercial translation.
  • Salk Institute for Biological Studies: California-based basic-research institute working on molecular and cellular biology with a comparable small-group, high-impact-discovery model and a history of technology commercialization.
  • Francis Crick Institute: London-based biomedical discovery institute with comparable scale (~1,500+ scientists), UK government/core-funding model, and broad molecular biology remit; the closest UK peer to LMB in mission, funding profile, and translational pipeline.
  • Rockefeller University: US graduate-research university with Nobel-rich tradition of small-lab molecular/cell biology; comparable in scale, talent density and historical commercialization of basic discoveries.
  • European Molecular Biology Laboratory (EMBL): Intergovernmental European molecular biology research organization with structural biology, bioinformatics, and instrumentation programmes directly comparable to LMB's cryo-EM and software work.
  • Howard Hughes Medical Institute (HHMI) Janelia Research Campus: HHMI's research campus shares LMB's model of small group-driven, technology-intensive fundamental biology (imaging, connectomics, tool-building) and is a named LMB collaboration partner.
  • Whitehead Institute for Biomedical Research: MIT-affiliated biomedical research institute with a similar small-group structure, focus on fundamental molecular/cell biology, and an active spin-out and licensing track record.
  • Max Planck Institute for Molecular Cell Biology and Genetics: German basic-research institute pursuing molecular cell biology with quantitative imaging and model-organism approaches; comparable in scientific scope and core-funding model.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat5 records

Key risks5 records

Key highlights7 records

Customer concentration

MRC Laboratory of Molecular Biology social profiles

Digital presence

MRC Laboratory of Molecular Biology financial estimates

Financial estimate

Revenue estimate

Valuation estimate

MRC Laboratory of Molecular Biology leadership team

Management profile

Number of profiles

Profiles3 records

MRC Laboratory of Molecular Biology funding detail

Funding detail

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

MRC Laboratory of Molecular Biology M&A and investment

M&A and investment

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about MRC Laboratory of Molecular Biology

What does MRC Laboratory of Molecular Biology do?

The MRC Laboratory of Molecular Biology (LMB) is a publicly funded fundamental research institute dedicated to understanding biological processes at atomic, molecular, cellular, and organismal levels. It pursues ambitious research across over 50 scientific groups using cutting-edge facilities such as cryo-electron microscopy, computational protein design, and brain connectomics. Outputs are disseminated to the global scientific community through open-access publications, open-source scientific software, training seminars, and technology commercialisation through licensing and spin-out companies.

Is MRC Laboratory of Molecular Biology a public or private company?

MRC Laboratory of Molecular Biology is a private company. It is classified as state government owned and is currently operating.

When was MRC Laboratory of Molecular Biology founded?

MRC Laboratory of Molecular Biology was founded in 1947. It employs 5,001 to 10,000 people.

Where is MRC Laboratory of Molecular Biology based?

MRC Laboratory of Molecular Biology is headquartered in Cambridge, United Kingdom, in the Europe region.

How does MRC Laboratory of Molecular Biology make money?

Two revenue lines are on record. Core Government Funding is the primary driver. The others are commercialization and Licensing.

Who are MRC Laboratory of Molecular Biology's main competitors?

Direct peers on record are Wellcome Sanger Institute, Scripps Research, Broad Institute of MIT and Harvard, Salk Institute for Biological Studies, Francis Crick Institute, Rockefeller University, European Molecular Biology Laboratory (EMBL), Howard Hughes Medical Institute (HHMI) Janelia Research Campus, Whitehead Institute for Biomedical Research and Max Planck Institute for Molecular Cell Biology and Genetics.

Does MRC Laboratory of Molecular Biology have an API?

No public API is recorded for MRC Laboratory of Molecular Biology.

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Live signals
BioWorldTRIM21 marks viruses and bacteria for degradation via autophagyTRIM21, an enzyme, recognizes antibody-coated viruses and bacteria in the cytosol and directs them to lysosomes via antibody-directed xenophagy (ADX). Scientists at the MRC Laboratory of Molecular Biology identified the genes involved in this pathway, which acts as an antimicrobial process, and reported the findings in Molecular Cell on June 4, 2026.GenengnewsNovel Intracellular Pathway Identified That Protects Against Viral and Bacterial InfectionResearchers identified a pathway called antibody-directed xenophagy (ADX) that degrades viruses and bacteria inside infected cells. The process is triggered by the protein TRIM21, which ubiquitinates antibody-coated pathogens and activates autophagy. The findings suggest potential therapeutic applications for treating infections.News-MedicalScientists discover new intracellular immune defense against infectionsScientists discovered antibody-directed xenophagy (ADX), a mechanism where cells digest bacteria and viruses that cross the cell membrane. TRIM21 flags antibody-labeled pathogens for degradation, and the pathway works in human cell lines and mouse models. Therapeutics could potentially mark pathogens to trigger ADX.AstrobiologyChemists Recreate How RNA Might Have Reproduced For The First TimeChemists at UCL and the MRC Laboratory of Molecular Biology demonstrated how RNA could replicate itself on early Earth using trinucleotide building blocks and pH-freeze-thaw cycles. The method overcame the strand-separation problem, enabling exponential replication of RNA strands, including a ribozyme fragment. The conditions could plausibly occur in geothermal environments.Cambridge IndependentAlzheimer Research Award won by MRC Laboratory of Molecular Biology scientistBenjamin Ryskeldi-Falcon of the MRC Laboratory of Molecular Biology has won the 2022 Alzheimer Research Award from the Hans and Ilse Breuer Foundation for his research on tau proteins in neurodegenerative diseases. He shares the award with Susanne Röhr from the University of Leipzig, who was recognized for healthcare research. The foundation highlighted the significance of this work in understanding disease mechanisms and developing future diagnostic tests and therapies.PhysScientists break resolution records to visualize individual atoms with single-particle cryo-EMScientists from the MRC Laboratory of Molecular Biology and Thermo Fisher Scientific have achieved atomic resolution in single-particle cryo-electron microscopy by resolving individual atoms within protein structures. By utilizing new hardware and advanced processing algorithms, the team produced a 1.22 Ångström resolution image of apoferritin, marking the highest resolution record for this technique and enabling the visualization of hydrogen atoms. This breakthrough allows for a deeper understanding of protein functions and facilitates the design of more specific drugs for treating various diseases.Cambridge IndependentRising star Dr Ben Falcon at MRC LMB explores role of tau in dementiaDr Benjamin Falcon at the MRC Laboratory of Molecular Biology has determined the distinct structures of tau filaments in Alzheimer's, Pick's disease, and chronic traumatic encephalopathy (CTE). This research identified a unique structural signature for CTE, including an extra molecule within the tau filaments that is absent in other dementias. These findings provide unifying neuropathological criteria for diagnosis and offer a pathway for developing more specific tracer compounds and treatments.AstrazenecaAstraZeneca and MRC Laboratory of Molecular Biology to launch joint research fundAstraZeneca announced a collaboration with the Medical Research Council Laboratory of Molecular Biology (MRC LMB) to launch a joint research fund for pre-clinical research projects aimed at understanding the biology of disease. AstraZeneca will contribute up to £6 million (approximately $10 million) and MRC LMB up to £3 million (approximately $5 million) over five years, with scientists from both organizations working side by side at MRC LMB facilities in Cambridge or AstraZeneca and MedImmune research sites. Projects supported by the fund will be pre-competitive, focusing on fundamental disease processes rather than specific drug development, with results intended to be published in peer-reviewed journals.