Fluidinova - Engenharia de Fluidos

What Fluidinova - Engenharia de Fluidos does

Fluidinova, S.A. is a Portugal-based specialty materials manufacturer founded in 2005 that produces synthetic nano-hydroxyapatite (HAp) and tricalcium phosphate (TCP) raw materials marketed under the nanoXIM® brand. Operating from Maia, Portugal with a workforce of 1-10 employees, the company sells exclusively to professional and industrial customers across four end-markets: oral care, medical and regenerative medicine, functional food and supplements, and academic research.

The product portfolio comprises 15 SKUs organized by particle size into nanometer pastes (e.g., nanoXIM·CarePaste, HAp101/102/103, SrHAp102), micrometer powders (e.g., CarePowder, HAp202/203/602, TCP200/600), and millimeter granules (G1000, G2000). Specialized variants include strontium-substituted hydroxyapatite with radiopaque properties for injectable bone substitutes, mesoporous structures, and calcined high-purity grades. nanoXIM·CarePaste holds a singular regulatory position as the only nano-hydroxyapatite officially recognized as safe for oral care in Europe by the SCCS, and food-grade variants carry FDA GRAS (21 CFR 182.1217) and E341(iii) approval. The brand is supported by a research library of hundreds of peer-reviewed publications citing nanoXIM materials.

Fluidinova operates a sales-led B2B model through a direct e-commerce storefront gated by account registration, with tiered minimum order quantities (≤1.0 kg or ≤5.0 kg for small orders, larger volumes for bulk) and unit pricing disclosed post-login. Distribution is supported by a warehouse in Maia, Portugal. Marketing is digital-first via the company website, technical data sheets, and LinkedIn/Facebook/X/YouTube channels aimed at industrial buyers, formulators, and researchers. Capitalization includes a $1.55M founding round from ChangePartners in 2005 and a subsequent round from Portugal Ventures in April 2021.

Name

Fluidinova - Engenharia de Fluidos

Legal name

FLUIDINOVA, S.A.

Website

https://fluidinova.com

Company type

Private

Founded year

2005

Operating status

Operating

Headcount range

1–10 employees

Short description

Fluidinova, S.A. manufactures synthetic nano-hydroxyapatite and tricalcium phosphate raw materials under the nanoXIM® brand, selling exclusively to professional and industrial buyers across oral care, medical devices, functional food, and academic research segments.

Ownership category

akta.pro rank

Headquarters

HQ city

Maia

HQ country

Portugal

HQ region

Europe

Offices2 records

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Operations, Personnel, Technology or R&D, Supply Chain, Marketing or Sales

Revenue model

1. Raw Materials Sales: FLUIDINOVA manufactures and sells synthetic hydroxyapatite and tricalcium phosphate materials as raw materials under the nanoXIM® brand. Products are sold in paste, powder, and granule forms to be incorporated by professionals into various applications including oral care products, medical devices, and functional foods. The company sells directly to professionals and industrial customers with minimum order quantities (≤1.0 kg for small orders, >1.0 kg for bulk orders).

Pricing tiers

Go-to-market motion1 record

Distribution channels2 records

Marketing channels7 records

Core offering

Fluidinova manufactures and sells synthetic hydroxyapatite and tricalcium phosphate materials as raw materials under the nanoXIM® brand. Products are supplied in paste, powder, and granule forms across nano, micro, and millimeter particle sizes for professional incorporation into oral care products, medical devices, functional foods, and research applications. The company sells exclusively to professionals and industrial customers through its own e-commerce platform and direct sales channels.

Product overview

Fluidinova specializes in the manufacture of synthetic hydroxyapatite (HAp) and tricalcium phosphate (TCP) materials sold as raw materials under the nanoXIM® brand. The product portfolio is organized across three particle size categories: nanometer-sized pastes (nanoXIM•CarePaste, nanoXIM•HAp101, nanoXIM•HAp102, nanoXIM•HAp103, nanoXIM•SrHAp102, nanoXIM•FoodPaste), micrometer-sized powders (nanoXIM•CarePowder, nanoXIM•HAp202, nanoXIM•HAp203, nanoXIM•HAp602, nanoXIM•TCP200, nanoXIM•TCP600, nanoXIM•FoodPowder), and millimeter-sized granules (nanoXIM•G1000, nanoXIM•G2000). These materials serve four main market segments: oral care (dental hypersensitivity, remineralization), medical/regenerative medicine (bone substitutes, implants, 3D printing), food (functional foods and supplements), and research. The company is the nano-hydroxyapatite specialist and has been a reference in the calcium phosphates market for over 15 years.

Differentiator

Problem solved

Functional benefit

Brands

• nanoXIM: Brand under which synthetic hydroxyapatite and tricalcium phosphate materials are sold as raw materials. nanoXIM® has been a reference figure in the calcium phosphates market for over 15 years.

Products and services

• nanoXIM•CarePaste Nano-hydroxyapatite aqueous suspension with rod-shaped particles <100 nm, the only nano-HAp officially recognized as safe for oral care in Europe by the SCCS. Marketed as a fluoride alternative for toothpaste, mouthwashes, and dental care products used by oral care manufacturers.
• nanoXIM•CarePowder Micro-hydroxyapatite powder sold as a raw material for incorporation by professionals into oral care products for remineralization and hypersensitivity applications.
• nanoXIM•HAp101 Nanometer-sized nano-hydroxyapatite paste supplied as a raw material for research and medical device applications.
• nanoXIM•HAp102 Nanometer-sized nano-hydroxyapatite paste for medical device applications including regenerative medicine and bone repair.
• nanoXIM•HAp103 Synthetic nano-hydroxyapatite aqueous paste with 30.0 ± 3.0 wt% nano-HAp concentration for medical devices, including injectable bone substitutes, implants, 3D printing scaffolds, and dermal fillers.
• nanoXIM•SrHAp102 Synthetic fully strontium-substituted nano-hydroxyapatite aqueous suspension (15.0 ± 1.0 wt%) with radiopacity for injectable bone substitutes, implants, and 3D printing applications.
• nanoXIM•HAp202 Synthetic nanostructured micro-hydroxyapatite powder for medical devices with particle size (d50) of 5.0 ± 1.0 µm.
• nanoXIM•HAp203 Synthetic nanostructured micro-hydroxyapatite powder for medical devices with particle size (d50) of 10.0 ± 2.0 µm and mesoporous structure.
• nanoXIM•HAp602 Synthetic calcined micro-hydroxyapatite powder for medical devices with controlled particle size distribution (Dv(10) ≤ 5.0 µm, Dv(50) ≤ 15.0 µm, Dv(90) ≤ 25.0 µm), low surface area (1–10 m²/g), and high phase purity (≥95% HAp).
• nanoXIM•TCP200 Synthetic calcium-deficient micro-hydroxyapatite powder for medical devices with particle size (d50) of 5.0 ± 2.0 µm, spherical microparticles, high porosity, and surface area >80 m²/g; non-calcined powder ensuring minimum β-TCP purity of 95% after calcination at 1000°C.
• nanoXIM•TCP600 Synthetic micro β-tricalcium phosphate powder for medical devices with controlled particle size distribution (Dv(10) ≤ 10.0 µm, Dv(50) ≤ 20.0 µm, Dv(90) ≤ 40.0 µm), low surface area, calcined, with ≥95% β-TCP phase purity.
• nanoXIM•G1000 Synthetic millimetric spherical hydroxyapatite granules for medical devices with particle size of 0.5–1.0 mm.
• nanoXIM•G2000 Synthetic millimetric spherical hydroxyapatite granules for medical devices with particle size of 1.0–2.0 mm; features uniform shape and size, optimal defect filling capacity, good flowability and handling properties, and osteostimulative properties.
• nanoXIM•FoodPaste Synthetic nano-hydroxyapatite aqueous suspension ingredient for functional foods and supplements, containing 15.5 wt% nano-HAp with rod-shaped particles <100 nm and paraben-free formulation; used in fortified beverages and chewing gums.
• nanoXIM•FoodPowder Synthetic micro-hydroxyapatite powder ingredient for functional foods and supplements with FDA GRAS status (21 CFR 182.1217) and E number E341(iii); small-sized microparticles, high purity, biocompatible, vegan; used in supplements and chewing gums for dental hypersensitivity prevention, bone strength promotion, and bone loss prevention.

Quantifiable outcome

• nano-sized materials hold 58% market share in global hydroxyapatite market (2025)
• +2 more outcomes

Named customers4 records

Segments4 records

Ideal customer profiles4 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

Feature3 records

Scale indicators2 records

Recent moves5 records

Expansion highlights5 records

Broad incumbents

• American Elements: US-based broad specialty chemicals and advanced materials catalog supplier offering research- and industrial-grade hydroxyapatite and other calcium phosphates. Adjacent competitor in research and industrial raw-material sales.
• Bio-Rad Laboratories: Global life-science research products manufacturer supplying laboratory-grade biomaterials, reagents, and reference standards used by academic and industrial researchers — overlapping customer base for Fluidinova's research-channel sales.
• Sigma-Aldrich (Merck Life Science): Global chemicals and life-science supplier (now part of Merck KGaA) offering research-grade hydroxyapatite and tricalcium phosphate materials. Competes in the research and dental raw-material channels as a broad incumbent catalog supplier.

Direct peers

• Plasma Biotal: UK-based manufacturer of hydroxyapatite powders and plasma-sprayed coatings for medical and dental implants. Comparable as a specialist calcium-phosphate supplier with overlapping medical-device end markets.
• Berkeley Advanced Biomaterials: Direct competitor manufacturing synthetic hydroxyapatite and other calcium phosphate biomaterials for orthopedics, dental, and research applications. Highly comparable as a small specialty biomaterials manufacturer selling raw-material inputs to medical-device and academic customers.
• Tateho Chemical Industries: Japanese manufacturer of specialty calcium phosphates and ceramic powders including hydroxyapatite for industrial, dental, and electronics applications. Comparable as a niche specialty calcium-phosphate producer with similar technical-grade product positioning.
• CAM Bioceramics: Direct peer producing calcium phosphate-based bone graft substitutes and bioceramic raw materials (incl. hydroxyapatite and TCP) for orthopedic and dental OEMs. Closely comparable specialty biomaterials business with similar regulatory and customer profiles.

Emerging players

• Promethean Particles: UK-based manufacturer of nanoparticle dispersions and continuous-flow nanomaterial manufacturing, including calcium phosphates. Emerging peer at the intersection of nano-scale specialty materials production.

Market position

Strengths4 records

Weaknesses4 records

Competitive moat4 records

Key risks5 records

Key highlights6 records

Customer concentration

• Xx.com/fluidinova
• YouTubeyoutube.com/user/FluidinovaSA
• Facebookfacebook.com/hydroxyapatite.fluidinova
• LinkedInlinkedin.com/company/fluidinova---engenharia-de-fluid

Revenue estimate

Valuation estimate

Number of profiles

Funding overview

Funding rounds2 records

Investors2 records

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about Fluidinova - Engenharia de Fluidos