SIELC Technologies

What SIELC Technologies does

SIELC Technologies is a privately held US manufacturer of liquid chromatography products, founded in 2002 and headquartered in Wheeling, Illinois. The company operates with 11-50 employees and sells globally through its own e-commerce storefront and a regional distributor network spanning the Americas, Asia, Australia, Europe, the Middle East, Africa, and Central Asia. Its product portfolio centers on proprietary mixed-mode HPLC stationary phases — including the Primesep®, Newcrom™, Obelisc™, BIST™, SHARC™, Promix™, Chromni™, and Cyralis™ column families — designed to separate complex mixtures using combinations of reverse-phase, ion-exchange, HILIC, hydrogen-bonding, and chiral interaction mechanisms that are difficult to achieve with conventional silica columns.

Complementing the column business, SIELC has built an instrument platform under the Alltesta™ brand (autosamplers, switching valves, syringe pumps, UV-Vis detectors, isocratic and gradient analyzers), the Cromite™ HPLC system, the Samplify™ automated sampling system, and HPLC.cloud software for instrument control. Patented column hardware and fittings, guard columns, and a Universal Adapter Kit complete the consumables and accessories stack. Revenue is generated primarily through hardware sales (columns, devices, accessories) with secondary professional-services revenue from custom method development and custom phase development. Customers include pharmaceutical companies (e.g., Merck & Co.), academic institutions (e.g., University of Cambridge), food and beverage testing labs, environmental testing labs, and cannabis testing labs. Pricing is quote-based and conducted in US dollars via direct online purchase or through regional distributors.

The business model is founder-owned with no disclosed external funding or institutional investors. Recent strategic activity has centered on product expansion (Cyralis chiral, Chromni universal column, Single-Ended column design, OligoMg oligonucleotide columns, Automated Swab System) and geographic distribution build-out (AGBL partnership in 2026), supported by industry recognition including Medical Tech Outlook's Top Liquid Chromatography Solution Provider 2025 award and six Lab Awards 2025 nominations.

Name

SIELC Technologies

Legal name

SIELC Technologies

Website

https://sielc.com

Company type

Private

Founded year

2002

Operating status

Operating

Headcount range

11–50 employees

Short description

SIELC Technologies manufactures proprietary HPLC columns, automated instruments, and chromatography accessories for liquid chromatography. The privately held company, founded in 2002 and based in Wheeling, Illinois, serves pharmaceutical, academic, food safety, environmental, and cannabis testing laboratories worldwide.

Ownership category

akta.pro rank

Product category

Analytical Laboratory Instruments

NAICS

Analytical Laboratory Instrument Manufacturing (334516)

SIC

Laboratory Analytical Instruments (3826), Laboratory Apparatus & Furniture (3821)

akta.pro primary industry

Analytical Instruments & Chromatography Systems (HLAGAIAA)

akta.pro secondary industry

Process Automation Instrumentation & Control (DCS, Valves, Actuators, Analyzers) (IMAHAHAM)

Keywords

• HPLC columns
• Liquid chromatography
• Mixed-mode chromatography
• Analytical instruments
• Chromatography accessories

Headquarters

HQ city

Wheeling

HQ country

United States

HQ region

North America

Offices1 record

Markets served

GTM type

B2B

Offering type

Hardware or Manufacturing

Cost components

Personnel, Technology or R&D, Supply Chain, Operations, Marketing or Sales

Revenue model

1. HPLC Columns and Chromatography Products: Sale of proprietary HPLC columns including Primesep, Newcrom, Obelisc, BIST, SHARC, and specialty columns for various chromatography applications. Available in multiple sizes from analytical to preparative scale.
2. HPLC Devices and Systems: Sale of Alltesta analyzers, Cromite HPLC systems, autosamplers, syringe pumps, UV-Vis detectors, and accessories for automated chromatography.
3. Custom Method Development Services: Custom HPLC method development services tailored for specific separations. Includes free custom method development requests for customers.
4. Custom Phase Development: Custom HPLC phases tailored for specific separations as a specialized service offering.
5. Fluidics and Accessories: Column hardware, fittings, tubing, filters, mobile phases, guard columns, and other HPLC accessories.
6. Preparative HPLC Services: Preparative HPLC service for larger-scale separations.

Pricing tiers

Go-to-market motion2 records

Distribution channels7 records

Marketing channels6 records

Core offering

SIELC Technologies designs, manufactures, and sells proprietary HPLC columns (Primesep, Newcrom, Obelisc, BIST, SHARC, Chromni, Cyralis, Lipak, Cannsep, Legacy, OligoMg) and supporting analytical devices (Alltesta automated analyzers, Cromite HPLC systems, mini autosamplers, syringe pumps, UV-Vis detectors, switching valves, Samplify sampling system). The company also offers HPLC.cloud software for instrument control, fluidic accessories (fittings, tubing, column hardware), and custom method/phase development services for pharmaceutical, academic, food safety, environmental, and cannabis testing laboratories.

Product overview

SIELC Technologies is a liquid chromatography company specializing in HPLC columns and analytical instruments. The product portfolio centers on proprietary mixed-mode chromatography columns (Primesep®, Newcrom™, Obelisc™, BIST™, SHARC™, Promix™) that combine multiple separation mechanisms for challenging applications. Supporting hardware includes the Alltesta™ line of automated analyzers and mini-devices (autosampler, syringe pumps, UV-Vis detector, switching valves), the Cromite™ HPLC System, and the Samplify™ automated sampling system. Cloud connectivity is provided through HPLC.cloud software. The portfolio also includes fluidic accessories (fittings, tubing, column hardware), guard columns, and custom phase/method development services. Recent additions include the Cyralis™ chiral column family, Chromni™ universal column, Single-Ended HPLC Column design, and the Alltesta™ Automated Swab System for security screening.

Differentiator

Problem solved

Functional benefit

Brands

• Chromni: Universal all-in-one HPLC column that eliminates the need for multiple specialized columns, performing reversed-phase, HILIC, ion-exchange, ion-exclusion, and normal phase separations.
• Single-Ended HPLC Column

Products and services

• Primesep HPLC Columns
• Newcrom HPLC Columns
• Obelisc HPLC Columns
• BIST HPLC Columns
• SHARC HPLC Columns
• Promix HPLC Columns
• Cannsep HPLC Columns
• Legacy HPLC Columns
• Solid-Core HPLC Columns
• Lipak HPLC Columns
• Chromni HPLC Column
• Cyralis Chiral HPLC Columns
• OligoMg HPLC Columns
• PVP HPLC Column
• Single-Ended HPLC Column
• Alltesta Isocratic Automated Analyzer
• Alltesta Gradient Automated Analyzer
• Cromite HPLC System
• Alltesta Mini Autosampler
• Alltesta Mini High-Pressure Switching Valve
• Alltesta Mini Liquid Handling Station (LHS)
• Alltesta Mini Syringe Pump
• Alltesta Mini LP Syringe Pump
• Alltesta Mini UV-Vis Detector
• Alltesta Power Tower
• Samplify Automated Sampling System
• Alltesta Automated Swab System
• HPLC.cloud Software
• Custom Phase Development Service
• Custom Method Development Service
• Preparative HPLC Service
• Universal Adapter Kit
• HPLC Fittings
• Guard Columns

Quantifiable outcome

• BIST™ provides separations traditionally difficult or impossible with other HPLC columns
• +3 more outcomes

Named customers2 records

Segments5 records

Ideal customer profiles5 records

Technology focussed Yes

API detail

Has API

No

API docs

API detail

Core technology

AI maturity

App detail

AI capability2 records

Feature8 records

Partnerships

One partnership is on record.

• AGBLregionalChannel Partner/ Reseller/ Distributor · 17 March 2026SIELC established distribution partnership with AGBL to support HPLC distribution and regional customer engagement across Africa, the Middle East, and Central Asia. This partnership expands SIELC's global distribution network to provide better customer service in these regions.

Scale indicators3 records

Recent moves6 records

Expansion highlights6 records

Broad incumbents

• Agilent Technologies: Dominant full-stack HPLC instrument, column, and software vendor. Competes with SIELC across columns (InfinityLab) and instruments, but at vastly larger scale with bundled solutions.
• Thermo Fisher Scientific: Major analytical instruments and chromatography consumables supplier (Thermo Scientific column and HPLC systems). Competes across columns, instruments, and software with significantly greater scale and distribution.
• Shimadzu Scientific Instruments: Major HPLC instrument and column manufacturer (Shim-pack, Nexera). Comparable as a bundled instrument-plus-columns supplier targeting pharma, environmental, and academic labs.
• Waters Corporation: Global leader in HPLC/UPLC systems, columns (Atlantis, ACQUITY), and informatics (Empower). Overlaps with SIELC's consumables and instrument product lines and competes for the same regulated lab customers.
• Bio-Rad Laboratories: Life science tools vendor with a chromatography consumables and standards portfolio. Adjacent overlap in HPLC quality-control and biopharma workflows where SIELC's mixed-mode columns are used.

Direct peers

• Phenomenex: Specialty HPLC column and consumables manufacturer (Luna, Kinetex, Gemini) with a similar product-led GTM into pharma, environmental, and food-testing labs. Directly comparable as a chromatography-focused consumables vendor serving overlapping customer segments.
• Restek Corporation: Independent specialty chromatography columns and accessories supplier serving pharma, environmental, and food safety labs. Comparable in scope, customer base, and channel model (direct + distributor) for HPLC columns and consumables.
• YMC Co., Ltd. Japanese specialty HPLC column manufacturer (YMC-Pack, Triart) focused on reversed-phase, HILIC, chiral, and bio-separations. Comparable as a global specialty column vendor with overlapping product categories to SIELC's Primesep, Newcrom, and Cyralis lines.
• Tosoh Bioscience: Specialty chromatography column and resin supplier for small-molecule and biopharma separations. Direct peer in HPLC columns, mixed-mode and ion-exchange chemistries, and similar pharma/biotech customer segments.

Emerging players

• Sepax Technologies: Specialty HPLC column manufacturer focused on mixed-mode, ion-exchange, and bio-separation chemistries. Comparable as a smaller specialty column vendor competing in similar niche separations and customer segments.

Market position

Strengths5 records

Weaknesses5 records

Competitive moat4 records

Key risks5 records

Key highlights6 records

Customer concentration

• Xx.com/sielc_tech

Revenue estimate

Valuation estimate

Number of profiles

Funding overview

Funding rounds

Investors

Funding detail is available on the Subscription and Enterprise plan.Contact sales →

M&A

Investments

M&A and investment is available on the Subscription and Enterprise plan.Contact sales →

Frequently asked questions about SIELC Technologies